Abstract:
OBJECTIVE:There is little knowledge about the tooth replacement in large mammals. The aim of this study is to investigate the tooth replacement patterns in Chinese miniature pig (Sus Scrofa). MATERIALS AND METHODS:The developmental patterns of mandibular successional and additional teeth from Chinese miniature pig before and after birth were investigated by microanatomy, immunohistochemistry, and cone beam computed tomography. RESULTS:Secondary dental lamina for successional teeth was not visible until its predecessor progressed to late bell stage. Successional teeth reached early cap stage when their predecessor began to erupt. The development patterns and speed varied between anterior and posterior successional teeth. Additional molars, derived from the free end of additional dental lamina, initiated sequentially in mandible ramus, while previous additional molar progressed into late bell stage. Proliferating cells in the permanent primordium were distributed asymmetrically. CONCLUSIONS:Our findings identify the characteristic patterns about spatiotemporal morphogenesis of successional teeth in context of their predecessor and cascade initiation of additional molars in miniature pigs. Our study provides a basis toward better understanding the mechanisms underlying diphyodont replacement in human and also assists in tooth regeneration and tooth engineering in large animal.
journal_name
Oral Disjournal_title
Oral diseasesauthors
Wang F,Xiao J,Cong W,Li A,Song T,Wei F,Xu J,Zhang C,Fan Z,Wang Sdoi
10.1111/odi.12126subject
Has Abstractpub_date
2014-05-01 00:00:00pages
367-79issue
4eissn
1354-523Xissn
1601-0825journal_volume
20pub_type
杂志文章相关文献
ORAL DISEASES文献大全abstract:OBJECTIVES:This study aimed to analyse Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) viral loads in symptomatic and asymptomatic apical periodontitis lesions, to determine levels of TNF-α, IL-1β and IL-6 in these lesions and to investigate a possible correlation between herpesviral copy numbers and levels o...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12829
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Periodontitis is a chronic inflammatory disease of the tissues supporting the teeth and is caused by subgingival plaque. Systemic increases in reactive oxygen species are involved in pathogenesis of periodontitis. This study addressed the relationship between levels of serum oxidative stress and antibodies ag...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12127
更新日期:2014-04-01 00:00:00
abstract::Salivary gland tumours represent a diverse range of tumours with many histological subtypes which occur in major and minor salivary glands. The management of these tumours is complex owing to their heterogeneity. Surgery together with radiotherapy and/or chemotherapy remains the treatment strategy for these tumours. T...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.12498
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the prevalence of oral sarcomas from geographic regions of Brazil. MATERIALS AND METHODS:A cross-sectional study was conducted on biopsies obtained from January 2007 to December 2016 at twelve Brazilian oral and maxillofacial pathology centres. Gender, age, evolution...
journal_title:Oral diseases
pub_type: 杂志文章,多中心研究
doi:10.1111/odi.13211
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Salivary glands are useful target organs for local and systemic gene therapeutics. For such applications, the regulation of transgene expression is important. Previous studies by us in murine submandibular glands showed that a rapamycin transcriptional regulation system in a single serotype 2, adeno-associat...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2009.01631.x
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:The Family with sequence similarity 5 member C (FAM5C) has been suggested to contribute in aggressive periodontitis. However, there is no data regarding its role in chronic periodontitis. The aim of this study was to evaluate the FAM5C expression in chronic periodontitis and to study association of FAM5C with...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2011.01855.x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:We examined the content of YouTube(™) videos on mouth (oral) cancer and evaluated their usefulness in promoting early detection of oral cancer. MATERIALS AND METHODS:A systematic search of YouTube(™) for videos containing information on mouth cancer was conducted using the keywords 'mouth cancer' and 'oral ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12434
更新日期:2016-04-01 00:00:00
abstract::Oral potentially malignant disorders (OPMDs) are associated with an increased risk of occurrence of cancers of the lip or oral cavity. This paper presents an updated report on the nomenclature and the classification of OPMDs, based predominantly on their clinical features, following discussions by an expert group at a...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13704
更新日期:2020-10-31 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the oral health status of chronic renal failure (CRF) patients on renal replacement therapy with a matched reference population. DESIGN:Cross-sectional study. SUBJECTS:Forty-two dentate CRF patients--aged 25-52 years old--were matched with a reference group of 808 dentat...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2005.01183.x
更新日期:2006-03-01 00:00:00
abstract::Gastroesophageal reflux disease (GERD) is a common medical condition affecting approximately 35-40% of the adult population in the western world. The role of GERD in causing extra-esophageal symptoms including laryngitis, asthma, cough, chest pain, and dental erosions is increasingly recognized with renewed interest a...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2007.01380.x
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:Clastic cells, originating from the monocyte-macrophage lineage, resorb mineralized tissues. In periapical periodontitis, alveolar bone around the tooth apex becomes resorbed; however, the roots of the teeth are often left intact by yet unknown mechanisms. Here, we examined the status of clastic cells in a...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12824
更新日期:2018-03-01 00:00:00
abstract::The deep mycoses are uncommon infections, usually acquired from the inhalation or ingestion of fungal spores, sometimes from the soil in areas of endemicity, such as in the Americas and south-east Asia, or from decaying vegetable matter. They are also seen in immunocompromised persons and, increasingly, in HIV-infecte...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.1997.tb00361.x
更新日期:1997-05-01 00:00:00
abstract:UNLABELLED:Abnormalities in the p53 gene are regarded as the most consistent genetic abnormalities detected in head and neck squamous cell carcinogenesis. Two new members of the p53 gene family, p73 at the 1p36 region and p63 at the 3q27-29 region, have recently been identified. They share considerable sequence homolog...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2003.02920.x
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:The management of the COVID-19 outbreak occurred in Lombardy (Italy) implied that non-COVID-19 health care was remodeled, limiting adequate resources in non-hospital public dental healthcare settings. This situation offered the opportunity to investigate the occupational COVID-19 risk to dental staff in publi...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13632
更新日期:2020-09-03 00:00:00
abstract:OBJECTIVE:To evaluate whether the oral functionality and the oral sensorimotor alterations are associated with oropharyngeal dysphagia in community-dwelling older persons and long-term care older residents. METHODS:An exploratory study with 265 independent older persons of the southern state of Brazil. The diagnosis o...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12809
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVES:Initial dental caries often occurs in clinic. Reduction of cariogenic bacteria and promotion of remineralization are effective ways to control them. This study was to develop bifunctional anticaries peptides with antibacterial and remineralizing properties. METHODS:We designed peptides TDH19, TNH19, and TVH...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12990
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Differences in genotype and phenotype of detoxification genes could be one reason for conflicting results in studies dealing with gene polymorphisms as susceptibility factors for tobacco associated cancer. OBJECTIVES:The objective of this study was to investigate gene polymorphisms of detoxification enzymes...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1034/j.1601-0825.2003.02866.x
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:The symptoms associated with burning mouth syndrome can be quite varied and can interfere with the every day lives of patients. Management of the condition can be challenging for clinicians. AIMS:To determine the oral health-related quality of life (OHRQOL) implications of BMS on patients over a period of t...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2010.01666.x
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To explore the type and prevalence of oral mucosal lesions among adults with primary HIV infection (PHI) compared with HIV-negative adults at high risk for HIV disease, and in relation to HIV viral load. METHODS:We conducted standardized oral examinations to identify specific oral mucosal lesions among adult...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01407.x
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:The present study was designed to investigate the effects of microRNA-21 (miR-21) on orthodontic tooth movement. METHODS:The orthodontic tooth movement model was established in C57BL/6 and miR-21-/- mice with or without implantation of activated T cells. Histological and histomorphometrical analyses were pe...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.13239
更新日期:2020-03-01 00:00:00
abstract::In order for chairside diagnostic testing to make an impact on dental therapy, practitioners require a better understanding of genetic mutations contributing to the pathophysiology of periodontal disease. Commensal and pathogenic bacterial colonization in oral cavity tissues produces a cascade of proinflammatory signa...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13030
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to investigate the prevalence of sleep bruxism in children in Japan, and its relationships with sleep-related factors and daytime problematic behavior. SUBJECTS AND METHODS:Guardians of 6023 children aged 2-12 years completed the Japanese Sleep Questionnaire. Multiple regression ...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12492
更新日期:2016-09-01 00:00:00
abstract::Apical periodontitis (AP) is a prevalent infectious and inflammatory disorder that involves inflammation of periapical tissues and the disintegration of alveolar bone. AP may eventually lead to tooth loss if not timely treated. This disease is caused by pathogenic bacteria in the necrotic pulps and root canals, thereb...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/odi.13450
更新日期:2020-06-02 00:00:00
abstract:BACKGROUND:Overexpression of fatty acid synthase (FAS), the cytosolic enzyme responsible for the conversion of dietary carbohydrates to fatty acids, has been reported in several human malignancies and pointed as a potential prognostic marker for some tumors. This study investigated whether FAS immunohistochemical expre...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2007.01395.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:An International Workshop addressed the prevalence and classification of HIV/ AIDS associated oral lesions. DESIGN:Five questions provided the framework for discussion and literature review. What is the prevalence of oral lesions in children and adults? Should the accepted classification of HIV-related oral...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1034/j.1601-0825.2002.00020.x
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the levels, molecular forms and activation degree of matrix metalloproteinase-13 (MMP-13) in the gingival crevicular fluid (GCF) of patients with periodontal diseases and to correlate these findings with periodontal clinical parameters. METHODS:Sixty one subjects pa...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/j.1601-0825.2006.01244.x
更新日期:2006-11-01 00:00:00
abstract::Oral Diseases (2011) 17, 252-257 Heme oxygenase (HO) system catabolizes heme into three products: carbon monoxide (CO), biliverdin/bilirubin and free iron, which consists of three forms identified to date: the oxidative stress-inducible protein HO-1 and the constitutive isozymes HO-2 and HO-3. HO has been involved in ...
journal_title:Oral diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1601-0825.2010.01732.x
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:Sodium lauryl sulphate (SLS) is the most commonly used detergent in dentifrices. Recent reports have suggested that it may exacerbate conditions with compromised epithelial integrity. The aim of this study was to compare the effect of an SLS-free dentifrice and an SLS-containing dentifrice on recurrent oral u...
journal_title:Oral diseases
pub_type: 临床试验,杂志文章
doi:10.1111/j.1601-0825.1999.tb00062.x
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To compare counts of Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Porphyromonas gingivalis and Fusobacterium nucleatum between crack users and non-users. MATERIALS AND METHODS:A cross-sectional study was conducted involving seventy-four crack cocaine users and eighty-one non-users matched fo...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12609
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:Orofacial clefts (OFCs) are common and etiologically complex birth defects. This study explored potential genetic differences in a pair of Japanese monozygotic (MZ) twins with different forms of OFC using whole-genome sequencing. SUBJECTS AND METHODS:One co-twin (MZ-1) presented with nonsyndromic bilateral c...
journal_title:Oral diseases
pub_type: 杂志文章
doi:10.1111/odi.12910
更新日期:2018-10-01 00:00:00