Abstract:
:An unusual case of tubercular granulomatous hypophysitis is reported. A sellar mass diagnosed as pituitary adenoma in MRI, showed non-caseating granulomas, glandular destruction and fibrosis in histology. Stain for acid-fast bacilli (AFB) were negative and the case was misdiagnosed as Idiopathic Granulomatous hypophysitis. The patient came back 2 weeks after trans-sphenoidal endoscopic resection with meningitis. CSF showed mixed pleocytosis. PCR for Mycobacterium tuberculosis was positive. The case is reported to highlight the need to maintain a high degree of suspicion for tuberculosis in any form of granulomatous hypophysitis, with or without caseous necrosis, in regions endemic for tuberculosis to prevent subsequent complications.
journal_name
Pituitaryjournal_title
Pituitaryauthors
Husain N,Husain M,Rao Pdoi
10.1007/s11102-007-0068-0subject
Has Abstractpub_date
2008-01-01 00:00:00pages
313-5issue
3eissn
1386-341Xissn
1573-7403journal_volume
11pub_type
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