Pituitary tuberculosis mimicking idiopathic granulomatous hypophysitis.

Abstract:

:An unusual case of tubercular granulomatous hypophysitis is reported. A sellar mass diagnosed as pituitary adenoma in MRI, showed non-caseating granulomas, glandular destruction and fibrosis in histology. Stain for acid-fast bacilli (AFB) were negative and the case was misdiagnosed as Idiopathic Granulomatous hypophysitis. The patient came back 2 weeks after trans-sphenoidal endoscopic resection with meningitis. CSF showed mixed pleocytosis. PCR for Mycobacterium tuberculosis was positive. The case is reported to highlight the need to maintain a high degree of suspicion for tuberculosis in any form of granulomatous hypophysitis, with or without caseous necrosis, in regions endemic for tuberculosis to prevent subsequent complications.

journal_name

Pituitary

journal_title

Pituitary

authors

Husain N,Husain M,Rao P

doi

10.1007/s11102-007-0068-0

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

313-5

issue

3

eissn

1386-341X

issn

1573-7403

journal_volume

11

pub_type

杂志文章
  • Aerosolisation in endonasal endoscopic pituitary surgery.

    abstract:PURPOSE:To determine the particle size, concentration, airborne duration and spread during endoscopic endonasal pituitary surgery in actual patients in a theatre setting. METHODS:This observational study recruited a convenience sample of three patients. Procedures were performed in a positive pressure operating room. ...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-021-01125-8

    authors: Dhillon RS,Nguyen LV,Rowin WA,Humphries RS,Kevin K,Ward JD,Yule A,Phan TD,Zhao YC,Wynne D,McNeill PM,Hutchins N,Scott DA

    更新日期:2021-01-19 00:00:00

  • Malignant transformation in non-functioning pituitary adenomas (pituitary carcinoma).

    abstract::Non-functioning pituitary carcinomas (NFPC) are defined as tumours of adenophyseal origin with craniospinal or systemic dissemination, with the absence of a hormonal hypersecretion syndrome. These are a histologically heterogenous group of tumours, comprising gonadotroph, null cell, "silent" tumours of corticotroph, s...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-017-0857-z

    authors: Lenders N,McCormack A

    更新日期:2018-04-01 00:00:00

  • The effect of somatostatin analogs and acromegaly on the upper gastrointestinal system.

    abstract:PURPOSE:To evaluate the effects of somatostatin analogs and disease activity status on the upper gastrointestinal system in patients with acromegaly. METHODS:One hundred eighty-one patients with acromegaly were retrospectively assessed. The demographic, biochemical, pathologic, and radiologic data of the patients were...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-020-01095-3

    authors: Sahin S,Icli TB,Durcan E,Sulu C,Ozkaya HM,Hatemi AI,Kadioglu P

    更新日期:2020-10-19 00:00:00

  • Geometric survey on magnetic resonance imaging of growth hormone producing pituitary adenoma.

    abstract::Apart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenom...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-013-0479-z

    authors: Bakhtiar Y,Hanaya R,Tokimura H,Hirano H,Oyoshi T,Fujio S,Bohara M,Arita K

    更新日期:2014-04-01 00:00:00

  • Prevalence of hematological abnormalities in patients with Sheehan's syndrome: response to replacement of glucocorticoids and thyroxine.

    abstract::Anemia and other hematological abnormalities are common in patients with Sheehan's syndrome. The response of these abnormalities to replacement of thyroxine and glucocorticoids is not clear. The aim of the present study was to document the profile of hematological abnormalities and response to treatment in patients wi...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-010-0255-2

    authors: Laway BA,Mir SA,Bashir MI,Bhat JR,Samoon J,Zargar AH

    更新日期:2011-03-01 00:00:00

  • Childhood craniopharyngioma.

    abstract::Craniopharyngiomas (CP) are partly cystic embryogenic malformations of the sellar and parasellar region. With an overall incidence of 0.5-2.0 new cases/million population/year, approximately 30-50 % of all cases represent childhood CP. Typical manifestations at diagnosis are headache, visual impairment, polyuria/polyd...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-012-0401-0

    authors: Müller HL

    更新日期:2013-03-01 00:00:00

  • Decreased insulin requirements after LAR-octreotide but not after lanreotide in an acromegalic patient.

    abstract::A diabetic acromegalic man, not cured after surgery and radiosurgery, received lanreotide i.m. with great clinical and biochemical improvement. He required NPH insulin (76 to 84 units/day) to control his diabetes mellitus. Thirty-six hours after changing to LAR-octreotide (20 mg i.m/month) he presented symptomatic hyp...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1020710800842

    authors: Webb SM,Ortega E,Rodríguez-Espinosa J,Mato ME,Corcoy R

    更新日期:2001-09-01 00:00:00

  • Management of recurrent pituitary cysts with pituitary-nasal drain.

    abstract::Pituitary cysts are usually craniopharyngiomas or remnants of Rathke's cleft. Histologically craniopharyngiomas are lined by stratified squamous epithelium whereas Rathke's cleft cysts are lined by cuboidal or columnar epithelium. The management of pituitary cysts remains difficult because of the risks associated with...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1025373715860

    authors: Dashora U,Mathias D,James A,Zammit-Maempel I,Perros P

    更新日期:2002-01-01 00:00:00

  • Moderate dose cranial radiotherapy causes central adrenal insufficiency in long-term survivors of childhood leukaemia.

    abstract::Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy. The survival rate in the Scandinavian countries is now around 85 %. ALL patients treated with cranial radiotherapy (CRT) are at risk for growth hormone deficiency (GHD), but little is known about other pituitary insufficiencies, e.g. ACTH. Ad...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0459-8

    authors: Follin C,Wiebe T,Moëll C,Erfurth EM

    更新日期:2014-02-01 00:00:00

  • Autoimmune lymphocytic hypophysitis in association with autoimmune eye disease and sequential treatment with infliximab and rituximab.

    abstract:INTRODUCTION:Autoimmune lymphocytic hypophysitis associates predominantly with other autoimmune endocrinopathies and is most commonly treated with glucocorticoids and/or decompressive pituitary surgery. Here we report a new association and treatment modality for lymphocytic hypophysitis. METHODS:A 52-year-old woman pr...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-014-0592-7

    authors: Xu C,Ricciuti A,Caturegli P,Keene CD,Kargi AY

    更新日期:2015-08-01 00:00:00

  • Management of aggressive pituitary adenomas: current treatment strategies.

    abstract::Aggressive pituitary adenomas are notoriously difficult to manage due to their size, invasiveness, speed of growth and high frequency of recurrence. Except for prolactinomas, surgery (usually transsphenoidal but sometimes transcranial) is the first-line option, but re-growth of aggressive tumors is almost inevitable a...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-008-0153-z

    authors: Buchfelder M

    更新日期:2009-01-01 00:00:00

  • Pathology of prolactinomas: any predictive value?

    abstract::Lactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas, constitute nearly 80% of functioning pituitary tumors and about 30-50% of all adenomas in the clinical practice. Lactotroph adenomas occur in the general population at a prevalence of 45/100,000, are more common in women, but also involve...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-019-00997-1

    authors: Lopes MBS

    更新日期:2020-02-01 00:00:00

  • Measurement of oxidative stress and endothelial dysfunction in patients with hypopituitarism and severe deficiency adult growth hormone deficiency.

    abstract::Patients with adult GH deficiency (AGHD) have a high cardiovascular risk and probably an alteration of the oxidative balance, although evidence is lacking. To evaluate the presence of endothelial dysfunction and oxidative stress in patients with AGHD. Biochemical parameters of oxidative stress and endothelial dysfunct...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-011-0374-4

    authors: González-Duarte D,Madrazo-Atutxa A,Soto-Moreno A,Leal-Cerro A

    更新日期:2012-12-01 00:00:00

  • Outcomes of stereotactic radiosurgery and hypofractionated stereotactic radiotherapy for refractory Cushing's disease.

    abstract:PURPOSE:Hypofractionated stereotactic radiotherapy (HSRT) for refractory Cushing's disease may offer a condensed treatment schedule for patients with large tumors abutting the optic chiasm unsuitable for stereotactic radiosurgery (SRS). To-date only four patients have been treated by HSRT in the published literature. W...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-019-00992-6

    authors: Sherry AD,Khattab MH,Xu MC,Kelly P,Anderson JL,Luo G,Utz AL,Chambless LB,Cmelak AJ,Attia A

    更新日期:2019-12-01 00:00:00

  • Inhibition of neuronal nitric oxide synthase activity does not alter vasopressin secretion in septic rats.

    abstract:BACKGROUND/PURPOSE:During the early phase of sepsis, hypotension is accompanied by increase of plasma vasopressin hormone (AVP) levels, which decline during the late phase. This hypotension is due in part to increase of nitric oxide (NO) synthesis by nitric oxide synthase (NOS) enzyme. Neuronal isoform of this enzyme (...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-017-0786-x

    authors: Coelho CH,Martins TF,Oliveira-Pelegrin GR,da Rocha MJA

    更新日期:2017-06-01 00:00:00

  • Staging and managing patients with acromegaly in clinical practice: baseline data from the SAGIT® validation study.

    abstract:PURPOSE:The SAGIT® instrument, designed to assist clinicians to stage acromegaly, assess treatment response and adapt patient management, was well received by endocrinologists in a pilot study. We report an interim analysis of baseline data from the validation phase. METHODS:The SAGIT® validation study (ClinicalTrials...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-019-00977-5

    authors: Giustina A,Bronstein MD,Chanson P,Petersenn S,Casanueva FF,Sert C,Houchard A,Melmed S

    更新日期:2019-10-01 00:00:00

  • Acromegaly in the setting of Tatton-Brown-Rahman Syndrome.

    abstract:PURPOSE:Tatton-Brown-Rahman syndrome (TBRS) is a newly defined genetic entity characterized by overgrowth and intellectual disability, resulting from germline mutations in the gene encoding DNA methyltransferase 3 alpha (DNMT3A). Affected individuals with benign and malignant tumors have been reported; to our knowledge...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-019-01019-w

    authors: Hage C,Sabini E,Alsharhan H,Fahrner JA,Beckers A,Daly A,Salvatori R

    更新日期:2020-04-01 00:00:00

  • Lanreotide extended-release aqueous-gel formulation, injected by patient, partner or healthcare provider in patients with acromegaly in the United States: 1-year data from the SODA registry.

    abstract::Lanreotide depot (LD; commercial name Somatuline(®) Depot) is an injectable, extended-release formulation of the synthetic somatostatin analog (SSA) lanreotide. In recent clinical trials, LD was found to be suitable for self or partner administration, avoiding the need to travel to a medical facility. The Somatuline(®...

    journal_title:Pituitary

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11102-012-0460-2

    authors: Salvatori R,Woodmansee WW,Molitch M,Gordon MB,Lomax KG

    更新日期:2014-02-01 00:00:00

  • Suprasellar pituitary adenomas: a 10-year experience in a single tertiary medical center and a literature review.

    abstract:BACKGROUND:Suprasellar pituitary adenomas (SPAs) are a special type of pituitary adenoma. Although dozens of SPA cases have been reported, the exact definition and the characteristics of SPA have not been exhaustively discussed before. METHODS:In a retrospective electronic medical records review, 13 patients with SPA ...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-020-01043-1

    authors: Zhu J,Wang Z,Zhang Y,Liu J,Li X,Deng K,Lu L,Yao Y

    更新日期:2020-08-01 00:00:00

  • Predictors of endoscopic transsphenoidal surgery outcome in acromegaly: patient and tumor characteristics evaluated by magnetic resonance imaging.

    abstract::The availability of various first-line treatment modalities for acromegaly and evolving surgical techniques emphasize the need for accurately defined predictors of surgical outcome. We retrospectively analysed the outcome of 30 patients with acromegaly after initial endoscopic transsphenoidal surgery in two university...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0395-7

    authors: van Bunderen CC,van Varsseveld NC,Baayen JC,van Furth WR,Aliaga ES,Hazewinkel MJ,Majoie CB,Freling NJ,Lips P,Fliers E,Bisschop PH,Drent ML

    更新日期:2013-06-01 00:00:00

  • Twelve cases of pituitary metastasis: a case series and review of the literature.

    abstract:PURPOSE:The pituitary gland is an unusual site for metastatic spread, but as patients with metastatic malignancy are living longer, it may become more prevalent. Compression of important anatomy adjacent to the sella may produce disabling symptoms and endocrine derangement, leading to significant morbidity. METHODS:An...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-018-0899-x

    authors: Castle-Kirszbaum M,Goldschlager T,Ho B,Wang YY,King J

    更新日期:2018-10-01 00:00:00

  • Minor tumour shrinkage in nonfunctioning pituitary adenomas by long-term treatment with the dopamine agonist cabergoline.

    abstract:OBJECTIVE:The purpose of this study was to define safety and efficacy of medical therapy in the treatment of nonfunctioning pituitary tumours. DESIGN:We studied thirteen patients with a clinically nonfunctioning pituitary macroadenoma for response to cabergoline treatment for 1 year. Twelve/13 patients were already op...

    journal_title:Pituitary

    pub_type: 临床试验,杂志文章

    doi:10.1023/a:1015366923810

    authors: Lohmann T,Trantakis C,Biesold M,Prothmann S,Guenzel S,Schober R,Paschke R

    更新日期:2001-08-01 00:00:00

  • Monotherapy with lanreotide depot for acromegaly: long-term clinical experience in a pituitary center.

    abstract:PURPOSE:Long-acting somatostatin analogs are one of the main classes of medical therapy used for acromegaly and most patients require ongoing treatment. Few studies have evaluated the long-term efficacy and safety of lanreotide depot beyond 2 years. The goal of this study was to provide a long-term longitudinal assessm...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-016-0724-3

    authors: Sagvand BT,Khairi S,Haghshenas A,Swearingen B,Tritos NA,Miller KK,Klibanski A,Nachtigall LB

    更新日期:2016-08-01 00:00:00

  • Acute presentation of craniopharyngioma in children and adults in a Danish national cohort.

    abstract::We aimed to study the occurrence of acute-onset symptoms at initial presentation in a national Danish cohort of patients with childhood- or adult-onset craniopharyngioma, and to investigate potential risk factors for acute presentation. Medical records of 189 consecutive patients (39 children, 150 adults) presenting w...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0451-3

    authors: Nielsen EH,Jørgensen JO,Bjerre P,Andersen M,Andersen C,Feldt-Rasmussen U,Poulsgaard L,Kristensen LØ,Astrup J,Jørgensen J,Laurberg P

    更新日期:2013-12-01 00:00:00

  • Cis-unsaturated free fatty acids block VIP-mediated GH and PRL secretion by perturbing the cAMP/protein kinase A pathway.

    abstract::Cis-unsaturated free fatty acids (FFA) like oleic acid are strong blockers of both basal and stimulated GH secretion in vivo by acting directly on the somatotroph cell. Several lines of evidence suggest that this inhibitory action is the result of a perturbation of the function of several plasma membrane integral prot...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1009962624036

    authors: Pérez FR,Camiña JP,Menéndez C,Beiras A,Casabiell X,Casanueva FF

    更新日期:1998-04-01 00:00:00

  • Effective time window in reducing pituitary adenoma size by gamma knife radiosurgery.

    abstract:OBJECTIVES:Although the effectiveness of gamma knife radiosurgery (GKRS) in controlling the size of pituitary adenomas has been well demonstrated in many studies, the time period in which significant changes in tumor size occurs has been investigated in a limited fashion. It is important to determine the therapeutic wi...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-014-0603-8

    authors: Mak HK,Lai SW,Qian W,Xu S,Tong E,Vance ML,Oldfield E,Jane J Jr,Sheehan J,Yau KK,Wintermark M

    更新日期:2015-08-01 00:00:00

  • Clinical picture and the treatment of TBI-induced hypopituitarism.

    abstract::Traumatic brain injury (TBI) is an important public health problem with an increasing incidence in the last years. Relatively few cases are fatal; most individuals will survive and, in the long-term, the sequalae of TBI will include neuroendocrine dysfunctions with a much higher frequency than previously suspected. Pa...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-019-00956-w

    authors: Caputo M,Mele C,Prodam F,Marzullo P,Aimaretti G

    更新日期:2019-06-01 00:00:00

  • Subclinical Cushing's syndrome.

    abstract::Clinically inapparent adrenal masses, or adrenal incidentalomas, are discovered inadvertently in the course of workup or treatment of unrelated disorders. Cortical adenoma is the most frequent type of adrenal incidentaloma accounting for approximately 50% of cases in surgical series and even greater shares in medical ...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-005-4024-6

    authors: Terzolo M,Reimondo G,Bovio S,Angeli A

    更新日期:2004-01-01 00:00:00

  • Gene expression profiling in human null cell pituitary adenoma tissue.

    abstract::It is estimated that up to one in five individuals develops pituitary gland tumors, despite the common occurrence of these tumors, the pathogenetic mechanisms underlying their development mainly remain unknown. We studied the gene expression in null cell adenomas compared with normal pituitary by expressed sequence ta...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-007-0008-z

    authors: Hu J,Song H,Wang X,Shen Y,Chen F,Liu Y,Li S,Wang Y,Shou X,Zhang Y,Hu R

    更新日期:2007-01-01 00:00:00

  • Can tissue biomarkers reliably predict the biological behavior of craniopharyngiomas? A comprehensive overview.

    abstract:BACKGROUND:The growing interest in the molecular and genetic alterations of craniopharyngiomas (CPs) is embodied in recent studies revealing insights into the CP tumorigenesis and identifying novel molecular pathways amenable of targeted therapies. The actual impact of this new information, however, remains inconclusiv...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-018-0890-6

    authors: Prieto R,Pascual JM

    更新日期:2018-08-01 00:00:00