Abstract:
:Apart from the radiologic features regarding size and invasiveness, we had noticed some differences in morphology among types of pituitary adenomas. We conducted this study to verify the differences in radiologic morphology between growth hormone producing pituitary adenomas (GHoma) and nonfunctioning pituitary adenomas (NFoma). Pre-surgical magnetic resonance images (MRIs) were assessed in 50 cases of GHoma and 50 cases of NFoma. Geometric parameters on MRI were set in accordance with sellar anatomy. Intensity of T1-weighted image was not different between the two groups, but hypo-intensity of T2-weighted image was more frequently seen in GHoma. Predominant inferior extension of tumor was seen mostly in GHoma (88 vs. 38%). Extension of the tumor to the superior compartment of cavernous sinus was more frequent in NFoma. Pituitary gland was generally located superior to GHoma and postero-superior to NFoma. Growth characteristics of pituitary adenoma were confirmed to differ between GHoma and NFoma.
journal_name
Pituitaryjournal_title
Pituitaryauthors
Bakhtiar Y,Hanaya R,Tokimura H,Hirano H,Oyoshi T,Fujio S,Bohara M,Arita Kdoi
10.1007/s11102-013-0479-zsubject
Has Abstractpub_date
2014-04-01 00:00:00pages
142-9issue
2eissn
1386-341Xissn
1573-7403journal_volume
17pub_type
杂志文章相关文献
Pituitary文献大全abstract:CONTEXT:Outcome of acromegaly surgery is assessed by IGF-1 and glucose-suppressed GH, but whether the latter provides additional clinically relevant information when IGF-1 is normal is unclear. The role of GH suppression testing after surgery requires clarification. METHODS:We studied 97 acromegaly patients with norma...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-020-01094-4
更新日期:2020-10-30 00:00:00
abstract::Aggressive pituitary adenomas are notoriously difficult to manage due to their size, invasiveness, speed of growth and high frequency of recurrence. Except for prolactinomas, surgery (usually transsphenoidal but sometimes transcranial) is the first-line option, but re-growth of aggressive tumors is almost inevitable a...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-008-0153-z
更新日期:2009-01-01 00:00:00
abstract::Adipsic diabetes insipidus (ADI) is a rare condition in which thirst, an essential clinical feature for the prevention of hypernatraemic dehydration, is absent. We report the first case of adipsic diabetes insipidus to occur following surgery for a pituitary macroprolactinoma, with loss of both osmoregulated and baror...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-006-8280-x
更新日期:2006-01-01 00:00:00
abstract::Published data on the effects of androgen deficiency and testosterone administration on body composition in men and women are reviewed. In experimental paradigms, androgen deprivation decreases lean body mass and increases fat mass in men, and physiologic replacement reverses these abnormalities. The anabolic effects ...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-008-0121-7
更新日期:2009-01-01 00:00:00
abstract::Lactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas, constitute nearly 80% of functioning pituitary tumors and about 30-50% of all adenomas in the clinical practice. Lactotroph adenomas occur in the general population at a prevalence of 45/100,000, are more common in women, but also involve...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-019-00997-1
更新日期:2020-02-01 00:00:00
abstract::Silent growth hormone adenomas (SGHA) are a rare entity of non-functioning pituitary neuroendocrine tumors. Diagnosis is invariably made post-operatively of a tumor immunopositive for GH (and Pit-1 in selected cases) but without clinical acromegaly. Mainly young females are affected, and tumors are often uncovered by ...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-017-0858-y
更新日期:2018-04-01 00:00:00
abstract::The dexamethasone (DXM) test has been widely used for diagnosing Cushing's disease (CD). The purpose of this paper is to review its diagnostic merit based on calculation of data extracted from earlier publications. Studies presenting individual values for patients with CD and normal subjects were identified through Pu...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-013-0509-x
更新日期:2014-08-01 00:00:00
abstract::Cushing's disease, i.e., pituitary ACTH-secreting adenoma causing excess glucocorticoid secretion, is a rare disease with significant mortality and morbidity. Timely diagnosis and appropriate treatment can alter the course of the disease and are therefore mandatory. First step of the diagnostic work-up is the endogeno...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-006-0407-6
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Autoimmune lymphocytic hypophysitis associates predominantly with other autoimmune endocrinopathies and is most commonly treated with glucocorticoids and/or decompressive pituitary surgery. Here we report a new association and treatment modality for lymphocytic hypophysitis. METHODS:A 52-year-old woman pr...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-014-0592-7
更新日期:2015-08-01 00:00:00
abstract::We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide. As a child, he had suffered a traumatic injury to his liver requiring the surgical repair of a laceration. This is the first reported case of hepatolithiasis...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1023/a:1012880113759
更新日期:2000-12-01 00:00:00
abstract::An unusual case of tubercular granulomatous hypophysitis is reported. A sellar mass diagnosed as pituitary adenoma in MRI, showed non-caseating granulomas, glandular destruction and fibrosis in histology. Stain for acid-fast bacilli (AFB) were negative and the case was misdiagnosed as Idiopathic Granulomatous hypophys...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-007-0068-0
更新日期:2008-01-01 00:00:00
abstract::Acromegaly is associated with serious morbidity and mortality, if not well controlled. Approved somatostatin receptor ligands (SRLs) are a mainstay of medical therapy and exhibit preferential affinity for somatostatin receptor (SSTR) subtype 2. Our objective was to assess whether characteristic features of individual ...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-012-0445-1
更新日期:2013-12-01 00:00:00
abstract:INTRODUCTION:In order to perform trans-sphenoidal endoscopic pituitary surgery safely and efficiently it is important to identify anatomical and pituitary disease features on the pre-operative CT and MRI scans; thereby minimising the risk to surrounding structures and optimising outcomes. We aim to create a checklist t...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-017-0787-9
更新日期:2017-08-01 00:00:00
abstract::We report the case of a B-cell type pituitary lymphoma in a 65 year-old male immunocompetent patient who presented with hypogonadotropic hypogonadism and central hypothyroidism and subsequently developed pulmonary lymphoma. Only three cases of pituitary lymphoma have been previously reported, one in a patient with acq...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1023/a:1009969417380
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:To evaluate the effects of somatostatin analogs and disease activity status on the upper gastrointestinal system in patients with acromegaly. METHODS:One hundred eighty-one patients with acromegaly were retrospectively assessed. The demographic, biochemical, pathologic, and radiologic data of the patients were...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-020-01095-3
更新日期:2020-10-19 00:00:00
abstract::Symptomatic cerebral vasospasm (CVS) after transsphenoidal surgery (TSS) is very rare compared with vasospasm resulting from aneurysmal subarachnoid hemorrhage (SAH). Fewer than six cases documented by cerebral angiography have been reported. We evaluated the records of 15 patients in whom SAH developed after TSS. The...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-012-0415-7
更新日期:2013-06-01 00:00:00
abstract::A 54-years-old woman diagnosed of myotonic dystrophy (MyD) with past medical history of massive postpartum haemorrhage at age 28 and panhypopituitarism was studied. BMI and body composition were determined and we determined baseline serum IGF-I, IGFBP3, insulin and leptin levels and after the IGF-I generation test per...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1023/a:1009984505312
更新日期:1999-01-01 00:00:00
abstract::Patients with adult GH deficiency (AGHD) have a high cardiovascular risk and probably an alteration of the oxidative balance, although evidence is lacking. To evaluate the presence of endothelial dysfunction and oxidative stress in patients with AGHD. Biochemical parameters of oxidative stress and endothelial dysfunct...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-011-0374-4
更新日期:2012-12-01 00:00:00
abstract::We evaluated the efficacy of Gamma knife stereotactic radiosurgery (GKSR) as an adjunctive management modality for patients with drug resistant or intolerant cavernous sinus invasive prolactinomas. Twenty-two patients with cavernous sinus invasive prolactinoma underwent GKSR between 1994 and 2009. Thirteen patients we...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-012-0376-x
更新日期:2013-03-01 00:00:00
abstract::Craniopharyngiomas (CP) are partly cystic embryogenic malformations of the sellar and parasellar region. With an overall incidence of 0.5-2.0 new cases/million population/year, approximately 30-50 % of all cases represent childhood CP. Typical manifestations at diagnosis are headache, visual impairment, polyuria/polyd...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-012-0401-0
更新日期:2013-03-01 00:00:00
abstract::Leptin is a key mediator in the maintenance of neuroendocrine homeostasis. The aim of this study was to determine the changes in serum leptin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), nitric oxide (NO) levels in patients with hyperprolactinemia. The study consists of 16 consecutive patients with ...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-008-0140-4
更新日期:2009-01-01 00:00:00
abstract::In this case report we describe a 38 year-old-female with galactorrhea several months after the birth of an anencephalic child. She had hyperpolactemia and imaging of the pituitary gland revealed a midline defect and a nasopharyngeal mass compatible with a meningo-(hypophyso-) encephalocele and possibly an ectopic ter...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-011-0320-5
更新日期:2012-12-01 00:00:00
abstract::The modern views on the anatomical and physiological interactions between the hypothalamus, pituitary and thyroid gland have emerged only in the last fifty years, although their historical roots may be found in a number of ancient and still not widely known ideas and observations. The regulation of energy body stores ...
journal_title:Pituitary
pub_type: 历史文章,杂志文章
doi:10.1023/a:1009953723963
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to define safety and efficacy of medical therapy in the treatment of nonfunctioning pituitary tumours. DESIGN:We studied thirteen patients with a clinically nonfunctioning pituitary macroadenoma for response to cabergoline treatment for 1 year. Twelve/13 patients were already op...
journal_title:Pituitary
pub_type: 临床试验,杂志文章
doi:10.1023/a:1015366923810
更新日期:2001-08-01 00:00:00
abstract::The role of pituitary radiotherapy (RT) in the management of clinically non-functioning pituitary tumors (NFTs) remains controversial. Observational studies suggest that RT is effective in preventing the regrowth of NFT remnants following initial surgical debulking. However, not all tumor remnants will regrow in the a...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1023/b:pitu.0000004801.95086.e2
更新日期:2003-09-01 00:00:00
abstract:INTRODUCTION:Cushing's syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality. MATERIALS AND METHODS:This review summarizes the main manifestations of Cushing's syndrome (active or in remission) with particu...
journal_title:Pituitary
pub_type: 杂志文章,评审
doi:10.1007/s11102-014-0631-4
更新日期:2015-04-01 00:00:00
abstract::The availability of various first-line treatment modalities for acromegaly and evolving surgical techniques emphasize the need for accurately defined predictors of surgical outcome. We retrospectively analysed the outcome of 30 patients with acromegaly after initial endoscopic transsphenoidal surgery in two university...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-012-0395-7
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:Thyrotropin-secreting pituitary adenoma is a rare disorder and was recently classified as an aggressive tumor in the World Health Organization guidelines. The number of available studies on cosecreting thyrotropin/growth hormone pituitary adenoma is especially limited. METHODS:A single-center retrospective ana...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-020-01064-w
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Granular cell tumors of the neurohypophysis are rare, solitary lesions, mostly presenting in the adult age. They rarely grow to a sufficient size to cause mass effect related symptoms and they may be found in most cases incidentally at autopsy. Because of their rarity as of now they have been described only as ...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-016-0704-7
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Severe fluctuations in plasma sodium concentration and plasma osmolarity, including central diabetes insipidus (CDI), may have significant influence on postoperative morbidity and mortality after pediatric brain tumor surgery.The aim of this study was to describe the frequency, severity and neurological consequ...
journal_title:Pituitary
pub_type: 杂志文章
doi:10.1007/s11102-018-0886-2
更新日期:2018-08-01 00:00:00