Abstract:
:A serosurvey targeting Hepatitis B virus (HBV)-vaccinated children born between 1986 and 1998 was conducted in 2001 in remote Taiwanese villages where a 1993 serosurvey indicated high vaccine failure. The HBV S antigen (HBsAg) seropositive rate among vaccinees of 3-6-year-old children in 2001 was significantly lower than that of 1993 and was higher among children who had a delayed vaccination schedule and received the plasma-derived vaccine. Vaccine escape variants were more prevalent among recipients of recombinant HBV vaccine residing in Hualien. Our study highlights the importance of continued monitoring of vaccinees for incidence of HBV infection in order to refine future vaccination policy.
journal_name
Vaccinejournal_title
Vaccineauthors
Huang ML,Liao WL,Ho MSdoi
10.1016/j.vaccine.2007.06.022subject
Has Abstractpub_date
2007-08-21 00:00:00pages
6326-33issue
34eissn
0264-410Xissn
1873-2518pii
S0264-410X(07)00699-8journal_volume
25pub_type
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