Achieving a "Grand Convergence" in global health by 2035.

abstract：BACKGROUND:To evaluate the immunological impact of the 23-valent pneumococcal polysaccharide vaccine (23vPPS) at 12 months, for children who have received zero to three infant doses of seven-valent pneumococcal conjugate vaccine (PCV), on responses to a subsequent exposure to a small dose of 23vPPS (mPPS). METHODS:Fiv...

journal_title：Vaccine

authors： Russell FM,Carapetis JR,Balloch A,Licciardi PV,Jenney AW,Tikoduadua L,Waqatakirewa L,Pryor J,Nelson J,Byrnes GB,Cheung YB,Tang ML,Mulholland EK

更新日期：2010-04-26 00:00:00

abstract：:Interleukin-5 (IL-5) is a cytokine which is essential for the maturation of eosinophils in bone marrow and for their release into the blood. Eotaxin is a CC type chemokine implicated in the recruitment of eosinophils in a variety of inflammatory disorders. Since eosinophil-activity is governed by these two pathways, w...

journal_title：Vaccine

authors： Zou Y,Sonderegger I,Lipowsky G,Jennings GT,Schmitz N,Landi M,Kopf M,Bachmann MF

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

journal_title：Vaccine

authors： Tsunekuni R,Tanikawa T,Nakaya T,Saito T

更新日期：2020-01-22 00:00:00

abstract：INTRODUCTION:Clinical trial data management (DM) conducted during outbreaks like that of Ebola virus disease (EVD) in West Africa, 2014-2016, has to adapt to specific, unique circumstances. CTU Bern was asked to set up a safe data capture/management system that could be launched within a few weeks and cover two differe...

journal_title：Vaccine

authors： Hossmann S,Haynes AG,Spoerri A,Diatta ID,Aboubacar B,Egger M,Rintelen F,Trelle S

更新日期：2019-11-15 00:00:00

abstract：:Two shots of inactivated Japanese encephalitis (JE) vaccine were given to children, 139 with underlying diseases and 42 healthy, and their antibody responses were studied by the neutralization test. Before vaccination, most of the vaccinees did not have antibody against JE virus. One month after the second vaccination...

journal_title：Vaccine

authors： Yamada A,Imanishi J,Juang RF,Fukunaga T,Okuno Y,Tadano M,Fukai K,Baba K,Yabuuchi H

更新日期：1986-03-01 00:00:00

abstract：:We have compared two types of plasmids for DNA immunization against HTLV-I envelope glycoproteins. One type of plasmid contains the coding DNA of the complete envelope gene of HTLV-I under the control of the CMV promoter with (CMVenvLTR) or without (CMVenv) the tax/rex genes. The second type contains the coding DNA of...

journal_title：Vaccine

authors： Armand MA,Grange MP,Paulin D,Desgranges C

更新日期：2000-04-28 00:00:00

abstract：:The effect of sublethal gamma-ray irradiation on the protection conferred by a nasal influenza vaccine was investigated in BALB/c mice. A radiation dose of 7 Gy was selected as the sublethal dose as this caused exacerbation of the influenza but was not lethal in the mouse model. Mice were irradiated 7 days before, on ...

journal_title：Vaccine

authors： Hasegawa H,Kadowaki S,Takahashi H,Iwasaki T,Tamura S,Kurata T

更新日期：2000-05-22 00:00:00

abstract：OBJECTIVE:To assess whether recipients and non-recipients of the human papillomavirus (HPV) vaccine subsequently differ in terms of sexual risk taking behaviour. DESIGN:Cross-sectional survey. Sequential analyses constructed from self-reported age at vaccination, age at first intercourse and age at response. SETTING:...

journal_title：Vaccine

authors： Hansen BT,Kjær SK,Arnheim-Dahlström L,Liaw KL,Jensen KE,Thomsen LT,Munk C,Nygård M

更新日期：2014-09-03 00:00:00

abstract：:During a pertussis epidemic in 2011-2012 the Western Australian (WA) Department of Health implemented a 'cocooning' programme, offering free pertussis-containing vaccine (dTpa) to new parents. We assessed the impact of vaccinating parents with dTpa on the incidence of pertussis infection in newborns. Births in WA duri...

journal_title：Vaccine

authors： Carcione D,Regan AK,Tracey L,Mak DB,Gibbs R,Dowse GK,Bulsara M,Effler PV

更新日期：2015-10-13 00:00:00

abstract：:Herpes zoster, a common disease, has an important impact on the health of adults, particularly the elderly, and the health system. This study evaluated the disease burden and epidemiological characteristics of herpes zoster in Taiwan. Using herpes zoster-related ICD-9-CM codes used on Taiwan's National Health Insuranc...

journal_title：Vaccine

authors： Lin YH,Huang LM,Chang IS,Tsai FY,Lu CY,Shao PL,Chang LY,Varicella-Zoster Working Group.,Advisory Committee on Immunization Practices, Taiwan.

更新日期：2010-02-03 00:00:00

abstract：:The emergence of pneumococcal strains resistant to penicillin caused a lot of problems in the therapy of invasive diseases, and added new dimensions to the role of immunisation. In addition to the currently available 23-valent pneumococcal polysaccharide vaccine (PPV) and a new 7-valent conjugate vaccine (PCV) (Prevna...

journal_title：Vaccine

authors： Paragi M,Kolman J,Kraigher A,Cizman M,Gubina M,Ribic H,Slovenian Meningitis Study Group.

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) vaccines were first licensed as a three-dose series; a two-dose series is now recommended in some age groups and there is interest in possible one-dose vaccination. METHODS:We conducted a systematic literature review of HPV vaccine effectiveness by number of doses, including asses...

journal_title：Vaccine

authors： Markowitz LE,Drolet M,Perez N,Jit M,Brisson M

更新日期：2018-08-06 00:00:00

abstract：:Carbopol is a polyanionic carbomer gel used in man for a variety of topical applications and drug delivery purposes. Here we show that subcutaneous administration of carbopol with glycoprotein antigens elicits unusually strong specific adaptive immune responses in mice. Recombinant soluble HIV-1 envelope glycoprotein ...

journal_title：Vaccine

authors： Krashias G,Simon AK,Wegmann F,Kok WL,Ho LP,Stevens D,Skehel J,Heeney JL,Moghaddam AE,Sattentau QJ

更新日期：2010-03-16 00:00:00

abstract：:Current available influenza vaccines are safe and effective in preventing influenza. Nevertheless, there is a need for influenza vaccines with improved efficacy in the elderly. This need is underscored by both the observation that influenza has a major clinical and economic impact in the elderly and the fact that curr...

journal_title：Vaccine

authors： de Bruijn IA,Nauta J,Cramer WC,Gerez L,Palache AM

更新日期：2005-07-08 00:00:00

abstract：:The aim of the present study was to investigate the immune response to native outer membrane vesicles (NOMVs) of Neisseria lactamica with and without Bordetella pertussis (BP) as adjuvant in intranasal (i.n./i.m) immunization. N. lactamica NOMVs delivered intranasally (i.n) to BALB/c mice in a final volume of 5microl ...

journal_title：Vaccine

authors： Ito AY,Néri S,Machado MS,Tunes CF,De Gaspari EN

更新日期：2009-05-26 00:00:00

abstract：:Porcine epidemic diarrhea (PED) is an important re-emergent infectious disease and inflicts huge economic losses to the swine industry worldwide. To meet the pressing need of developing a safe and cost-efficient PED maternal vaccine, we generated three PED subunit vaccine candidates, using recombined Salmonella flagel...

journal_title：Vaccine

authors： Li Q,Peng O,Wu T,Xu Z,Huang L,Zhang Y,Xue C,Wen Z,Zhou Q,Cao Y

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:Little is known about inactivated influenza vaccine effectiveness (IVE) in preventing very severe disease, including influenza-associated intensive care unit (ICU) admissions. METHODS:The Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance (SHIVERS) project enrolled adults (age...

journal_title：Vaccine

authors： Thompson MG,Pierse N,Sue Huang Q,Prasad N,Duque J,Claire Newbern E,Baker MG,Turner N,McArthur C,SHIVERS investigation team.

更新日期：2018-09-18 00:00:00

abstract：:As companies, countries, and governments consider investments in vaccine production for routine immunization and outbreak response, understanding the complexity and cost drivers associated with vaccine production will help to inform business decisions. Leading multinational corporations have good understanding of the ...

journal_title：Vaccine

authors： Plotkin S,Robinson JM,Cunningham G,Iqbal R,Larsen S

更新日期：2017-07-24 00:00:00

abstract：:T-lymphocyte responses to influenza vaccination were measured in healthy young and older adult volunteers. All participants were vaccinated with the 1995-96 trivalent influenza vaccine. Cytokine and granzyme B levels were measured in peripheral blood mononuclear cells (PBMC) cultures after virus stimulation, prior to ...

journal_title：Vaccine

authors： McElhaney JE,Upshaw CM,Hooton JW,Lechelt KE,Meneilly GS

更新日期：1998-11-01 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:The continued use of oral polio vaccine (OPV) poses a threat to polio virus eradication. Stopping all polio vaccination in the post-certification era is no longer considered to be a practical option. Policy makers agree that OPV use must stop immediately after certification. Therefore, the pragmatic alternative is for...

journal_title：Vaccine

authors： Khan MM

更新日期：2008-04-07 00:00:00

abstract：BACKGROUND:In 1999, the American Academy of Pediatrics (AAP) and the U.S. Public Health Service (USPHS) issued a joint statement on thimerosal in vaccines, which advised clinicians to temporarily postpone the first dose of hepatitis B vaccine for infants born to hepatitis B surface antigen (HBsAg)-negative women. In 20...

journal_title：Vaccine

authors： Zhao Z,Murphy TV,Jacques-Carroll L

更新日期：2011-12-09 00:00:00

abstract：INTRODUCTION:The recent emergence of avian influenza strains has fuelled concern about pandemic preparedness since vaccines targeting these viruses are often poorly immunogenic. Weak antibody responses to vaccines have been seen across multiple platforms including plant-made VLPs. To better understand these differences...

journal_title：Vaccine

authors： Hendin HE,Pillet S,Lara AN,Wu CY,Charland N,Landry N,Ward BJ

更新日期：2017-05-02 00:00:00

abstract：:Interest in addressing antimicrobial resistance (AMR) has grown recently but little effort has been made to consider how existing and new vaccines could impact on AMR. A 2017 Chatham House meeting considered the role of vaccines and how to demonstrate their value through their impact on AMR. Ways existing vaccines hav...

journal_title：Vaccine

authors： Clift C,Salisbury DM

更新日期：2017-12-04 00:00:00

abstract：:The severe acute respiratory syndrome coronavirus nucleocapsid protein (SARS-CoV N) is one of the major targets for SARS vaccine due to its high potency in triggering immune responses. In this study, we have identified a novel HLA-A*0201 restricted epitope, N220 (LALLLLDRL), of the SARS-CoV N-protein through bioinform...

journal_title：Vaccine

authors： Cheung YK,Cheng SC,Sin FW,Chan KT,Xie Y

更新日期：2007-08-10 00:00:00

abstract：:The predominant route of HIV infection is through the sexual transmission via M cells. Most of the peptide and protein vaccines show poor transport across the epithelial barrier and are commonly administered by parenteral route. In the present study four HIV peptides from envelope (gp 41-LZ (leucine zipper), gp 41-FD ...

journal_title：Vaccine

authors： Manocha M,Pal PC,Chitralekha KT,Thomas BE,Tripathi V,Gupta SD,Paranjape R,Kulkarni S,Rao DN

更新日期：2005-12-01 00:00:00

abstract：:Polysaccharides (PSs) derived from Streptococcus pneumoniae include more than 90 serotypes and differ greatly in their immunogenicity. In addition, immunization with PSs does not induce high affinity antibody production and no memory B-cells are generated. Coupling PSs to carrier proteins has been reported to induce B...

journal_title：Vaccine

authors： Libon C,Haeuw JF,Crouzet F,Mugnier C,Bonnefoy JY,Beck A,Corvaïa N

更新日期：2002-05-22 00:00:00

abstract：:The safety and immunogenicity of a single dose of virosome-formulated hepatitis A vaccine was evaluated in healthy seronegative Thai volunteers. Immunization elicited primarily mild transient reactions which did not interfere with normal activities. All subjects possessed > 20 mIU of anti-hepatitis A virus antibody pe...

journal_title：Vaccine

authors： Poovorawan Y,Theamboonlers A,Chumdermpadetsuk S,Glück R,Cryz SJ Jr

更新日期：1995-07-01 00:00:00

abstract：:During the pandemic (H1N1) 2009 vaccination campaign, vaccine providers collected immunization data using hybrid (paper-based and electronic methods) and electronic data systems. We measured staff time in seconds spent on data collection tasks to compare system efficiencies. The sample consisted of 38 organizations ac...

journal_title：Vaccine

authors： Quach S,Hamid JS,Pereira JA,Heidebrecht CL,Foisy J,Bettinger JA,Rosella L,Crowcroft NS,Deeks SL,Quan SD,Finkelstein M,Guay M,Buckeridge DL,Sikora CA,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Res

更新日期：2011-02-24 00:00:00

abstract：:Oral administration of antigen is known to be appropriate for some vaccine purposes as well as oral tolerance induction. In the present study, oral administration of beta-lactoglobulin (BLG) loaded poly(D,L-lactide-co-glycolide) (D,L-PLG) microspheres induced tolerance was evaluated. A single feeding of 5 micrograms o...

journal_title：Vaccine

authors： Pecquet S,Leo E,Fritsché R,Pfeifer A,Couvreur P,Fattal E

更新日期：2000-01-18 00:00:00