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Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines.

Abstract：

:The adjuvant effect of Quil A on the primary antibody response of mice to pneumococcal capsular polysaccharide conjugates was examined. Quil A increased the anti-capsular polysaccharide antibody titres, the protection against Streptococcus pneumoniae, and the opsonic capacity of the antibodies as measured in a newly developed in vitro phagocytosis assay, using the mouse macrophage cell line J774.

journal_name

Vaccine

journal_title

Vaccine

authors

DeVelasco EA,Dekker HA,Antal P,Jalink KP,van Strijp JA,Verheul AF,Verhoef J,Snippe H

doi

10.1016/0264-410x(94)90151-1

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

1419-22

issue

15

eissn

0264-410X

issn

1873-2518

pii

0264-410X(94)90151-1

journal_volume

12

pub_type

杂志文章

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