Human lactoferrin proteolytic activity: analysis of the cleaved region in the IgA protease of Haemophilus influenzae.

abstract：:Inactivated porcine parvovirus (PPV) vaccines are available commercially and widely used in the breeding herds. However, inactivated PPV vaccines have deficiencies in induction of specific cellular immune response. Transfer factor (TF) is a material that obtained from the leukocytes, and is a novel immune-stimulatory ...

journal_title：Vaccine

authors： Wang RN,Wang YB,Geng JW,Guo DH,Liu F,Chen HY,Zhang HY,Cui BA,Wei ZY

更新日期：2012-07-27 00:00:00

abstract：:The efficacy of a licensed human anthrax vaccine (Anthrax Vaccine Adsorbed (AVA)) was tested in guinea pigs, rabbits, and rhesus macaques against spore challenge by Bacillus anthracis isolates of diverse geographical origin. Initially, groups of Hartley guinea pigs were vaccinated at 0 and 4 weeks with AVA, then chall...

journal_title：Vaccine

authors： Fellows PF,Linscott MK,Ivins BE,Pitt ML,Rossi CA,Gibbs PH,Friedlander AM

更新日期：2001-04-30 00:00:00

abstract：:A reassortant virus possessing RNA segment 7, which codes for the M1 and M2 proteins, of the avian influenza A/Mallard/New York/6750/78 (H2N2) virus and the other seven RNA segments of the human influenza A/Udorn/307/72 (H3N2) virus had been shown previously to be markedly restricted in replication in the respiratory ...

journal_title：Vaccine

authors： Murphy BR,Buckler-White AJ,London WT,Snyder MH

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Public concern about an unsubstantiated link between MMR vaccine and autism stemmed from a 1998 paper by Dr Andrew Wakefield and colleagues, and the substantial media coverage which that work attracted. Though the Wakefield paper is now discredited and an MMR-autism link has never been demonst...

journal_title：Vaccine

authors： Brown KF,Long SJ,Ramsay M,Hudson MJ,Green J,Vincent CA,Kroll JS,Fraser G,Sevdalis N

更新日期：2012-02-27 00:00:00

abstract：:Ten prospective clinical trials conducted in elderly and high-risk adults have failed to show that pneumococcal vaccine prevents pneumococcal bacteraemia and all pneumonia. Several of these trials focused on unrepresentative populations and most had serious methodological problems. Few adequately considered sample siz...

journal_title：Vaccine

authors： Fedson DS,Liss C

更新日期：2004-02-25 00:00:00

abstract：:Capsular polysaccharides are important virulence factors of Streptococcus pneumoniae. The polysaccharide has been used as a component of vaccines against pneumococcal diseases either as plain polysaccharide or better conjugated to a protein. The last one is the vaccine of choice to target child protection. The immune ...

journal_title：Vaccine

authors： Chang J,Serrano Y,Garrido R,Rodríguez LM,Pedroso J,Cardoso F,Valdés Y,García D,Fernández-Santana V,Verez-Bencomo V

更新日期：2012-11-19 00:00:00

abstract：:Age related deterioration in the function of the immune system has been recognised in many species. The clinical presentations of such immune dysfunction are an age-related increased susceptibility to certain infections, and an increased incidence of autoimmune disease and certain cancers. Laboratory investigations re...

journal_title：Vaccine

authors： Aspinall R,Andrew D

更新日期：2000-02-25 00:00:00

abstract：OBJECTIVE:Implementing national-level vaccination programs involves long-term investment, which can be a significant financial burden, particularly in resource-limited settings. Although many studies have assessed the economic impacts of providing vaccinations, evidence on the positive and negative implications of huma...

journal_title：Vaccine

authors： Chootipongchaivat S,Chantarastapornchit V,Kulpeng W,Ceria JA,Tolentino NI,Teerawattananon Y

更新日期：2016-09-14 00:00:00

abstract：:In this study, West Nile virus (WNV) envelope (rE) protein and its domain III (rDIII) were efficiently expressed in a cost-effective system based on insect larvae as non-fermentative living biofactories. Mice immunized with the partially purified rE or rDIII elicited high antibodies titers that neutralized viral infec...

journal_title：Vaccine

authors： Alonso-Padilla J,de Oya NJ,Blázquez AB,Escribano-Romero E,Escribano JM,Saiz JC

更新日期：2011-02-17 00:00:00

abstract：:In this review, published peer-reviewed preclinical studies using prime-boost tuberculosis (TB) vaccine regimens in animal challenge models for tuberculosis have been evaluated. These studies have been divided into groups that describe prime-boost vaccine combinations that performed better than, equivalent to, or wors...

journal_title：Vaccine

authors： Brennan MJ,Clagett B,Fitzgerald H,Chen V,Williams A,Izzo AA,Barker LF

更新日期：2012-04-16 00:00:00

abstract：:Rotavirus causes approximately 450,000 deaths annually among children less than 5 years of age worldwide, almost half of which occur in Africa. After the recent completion of successful trials of 2 new rotavirus vaccines, the World Health Organization has recommended these vaccines for all children worldwide. Because ...

journal_title：Vaccine

authors： Steele AD,Patel M,Cunliffe NA,Bresee JS,Borgstein E,Parashar UD

更新日期：2012-04-27 00:00:00

abstract：:During the pandemic (H1N1) 2009 vaccination campaign, vaccine providers collected immunization data using hybrid (paper-based and electronic methods) and electronic data systems. We measured staff time in seconds spent on data collection tasks to compare system efficiencies. The sample consisted of 38 organizations ac...

journal_title：Vaccine

authors： Quach S,Hamid JS,Pereira JA,Heidebrecht CL,Foisy J,Bettinger JA,Rosella L,Crowcroft NS,Deeks SL,Quan SD,Finkelstein M,Guay M,Buckeridge DL,Sikora CA,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Res

更新日期：2011-02-24 00:00:00

abstract：:Induction of broad HIV-1 neutralizing antibodies should be a major goal of an effective HIV-1 vaccine. However, B cells are severely damaged during HIV-1 infection with loss of memory B cells and decline of serological memory. The molecular events leading to B cell damage must be further characterized with the aim of ...

journal_title：Vaccine

authors： Cagigi A,Nilsson A,De Milito A,Chiodi F

更新日期：2008-06-06 00:00:00

abstract：:ErbB-2 is associated with several solid tumours of which breast cancer is the commonest cancer in women worldwide. Though anti-ErbB-2 antibody appears to play a significant role in prevention and therapy, naturally occurring anti-ErbB-2 antibody associated with the cleaved ectodomain of overexpressed ErbB-2 self antig...

journal_title：Vaccine

authors： Mukhopadhyay A,Dyring C,Stott DI

更新日期：2014-02-12 00:00:00

abstract：:We assessed the tetanus immunity of the general Dutch population and of religious groups refusing vaccination by means of population-based study to evaluate the effect of tetanus vaccination. More than 95% of those born after the introduction of routine vaccination had tetanus antitoxin levels above the minimum protec...

journal_title：Vaccine

authors： de Melker HE,van den Hof S,Berbers GA,Nagelkerke NJ,Rümke HC,Conyn-van Spaendonck MA

更新日期：1999-08-20 00:00:00

abstract：BACKGROUND:It is known that antineoplastic treatment may induce secondary immunodeficiency, but studies after childhood sarcoma are rare. Since 1998, the Late Effects Surveillance System (LESS) of the German Society for Paediatric Oncology and Haematology (GPOH) prospectively registers late effects in soft tissue-, ost...

journal_title：Vaccine

authors： Paulides M,Stöhr W,Laws HJ,Graf N,Lakomek M,Berthold F,Schmitt K,Niggli F,Jürgens H,Bielack S,Koscielniak E,Klingebiel T,Langer T

更新日期：2011-02-11 00:00:00

abstract：:Immunological memory induced by nasal immunization with adjuvant-combined influenza vaccine was analyzed in different ages and strains of mice. The memory activities were assessed by secondary nasal-wash IgA and serum IgG antibody (Ab) responses and protection against challenge infection with a lethal dose of influenz...

journal_title：Vaccine

authors： Asanuma H,Fujihashi K,Miyakoshi T,Yoshikawa T,Fujita-Yamaguchi Y,Kojima N,Nakata M,Suzuki Y,Tamura S,Kurata T,Sata T

更新日期：2007-09-28 00:00:00

abstract：:As a recently launched novel vaccine used as one of the vaccines for the final eradication of polios worldwide, complete data on the consistency and immunogenicity characteristics of the inactivated poliomyelitis vaccine made from the Sabin strain (sIPV) and its safety in large-scale populations are required to suppor...

journal_title：Vaccine

authors： Jiang R,Liu X,Sun X,Wang J,Huang Z,Li C,Li Z,Zhou J,Pu Y,Ying Z,Yin Q,Zhao Z,Zhang L,Lei J,Bao W,Jiang Y,Dou Y,Li J,Yang H,Cai W,Deng Y,Che Y,Shi L,Sun M

更新日期：2021-01-21 00:00:00

abstract：:A DNA vaccine codifying the mycobacterial hsp65 can prevent infection with Mycobacterium tuberculosis in a prophylactic setting and also therapeutically reduce the number of bacteria in infected mice. The protective mechanism is thought to be related to Th1-mediated events that result in bacterial killing. To determin...

journal_title：Vaccine

authors： Lima KM,dos Santos SA,Santos RR,Brandão IT,Rodrigues JM Jr,Silva CL

更新日期：2003-12-08 00:00:00

abstract：BACKGROUND:Alternative methods for influenza vaccine production are needed to ensure adequate supplies. METHODS:Healthy adults 50-64 years were assigned randomly to receive one intramuscular injection of trivalent recombinant hemagglutinin (rHA) or U.S. licensed trivalent inactivated vaccine (TIV) containing H1, H3 an...

journal_title：Vaccine

authors： Baxter R,Patriarca PA,Ensor K,Izikson R,Goldenthal KL,Cox MM

更新日期：2011-03-09 00:00:00

abstract：:An effective malaria vaccine remains a global health priority. Recombinant adenoviruses are a promising vaccine platform, and Plasmodium falciparum apical membrane antigen 1 (AMA1) and merozoite surface protein 1-42 (MSP1(42)) are leading blood stage vaccine candidates. We evaluated the importance of surface antigen l...

journal_title：Vaccine

authors： Bruder JT,Stefaniak ME,Patterson NB,Chen P,Konovalova S,Limbach K,Campo JJ,Ettyreddy D,Li S,Dubovsky F,Richie TL,King CR,Long CA,Doolan DL

更新日期：2010-04-19 00:00:00

abstract：:As a step in the development of an oral vaccine against ETEC, we evaluated the safety and immunogenicity of CS6, a polymeric protein commonly found on the surface of ETEC. Formulations included 1 and 5mg doses of CS6, either encapsulated in biodegradable polymer poly(D, L)-lactide-co-glycolide (PLG), or as free protei...

journal_title：Vaccine

authors： Katz DE,DeLorimier AJ,Wolf MK,Hall ER,Cassels FJ,van Hamont JE,Newcomer RL,Davachi MA,Taylor DN,McQueen CE

更新日期：2003-01-17 00:00:00

abstract：:Recipients of renal transplants were vaccinated with 20 ng hepatitis B surface antigen aluminium-adsorbed vaccine in order to gauge their resistance to hepatitis B infection, to which these patients are at high risk. The patients were given three 40 micrograms doses of the vaccine over a period of six months and their...

journal_title：Vaccine

authors： Feuerhake A,Muller R,Lauchart W,Pichlmayr R,Schmidt FW

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Theories of health behavior change are being inadequately adopted to understand the reasons behind low influenza vaccination rates among healthcare workers (HCWs). The Theory of Planned Behavior (TPB) is being used to predict intention-behavior relationship while the Health Belief Model (HBM) is being employ...

journal_title：Vaccine

authors： Alhalaseh L,Fayoumi H,Khalil B

更新日期：2020-10-27 00:00:00

abstract：:In this article, we review three mechanisms that contribute to sustaining serum antibody levels: (i) long-lived plasma cells; (ii) persisting or cross-reactive antigen, and (iii) polyclonal activation of all memory B cells. We also present a quantitative analysis of the secondary immune response that reveals the relat...

journal_title：Vaccine

authors： Traggiai E,Puzone R,Lanzavecchia A

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Although guidelines for prophylactic human papillomavirus (HPV) vaccination recommend two doses for girls ages 9-14 years, several studies have demonstrated similar protection with one dose. Our objective was to evaluate the long-term health and economic impacts of routine one-dose HPV vaccination compared t...

journal_title：Vaccine

authors： Burger EA,Campos NG,Sy S,Regan C,Kim JJ

更新日期：2018-08-06 00:00:00

abstract：:Through the specific and tight interaction between streptavidin and biotin, a novel platform was developed to allow for rapid (less than 2h), efficient and durable display of streptavidin-tagged bioactive GM-CSF on the surface of biotinylated B16.F10 tumor cells. This technology involved biotinylation of the cell memb...

journal_title：Vaccine

authors： Gao J,Huang S,Li M,Luo R,Wang X,Takashima A

更新日期：2006-06-19 00:00:00

abstract：:Two live recombinant vaccines (Flc9 and Flc11) against classical swine fever (CSF) were evaluated for their capacity to reduce transmission of virulent CSF virus (CSFV) among vaccinated pigs. In Flc9 the 5' terminal half of the E2 gene of the C-strain, a CSFV vaccine strain, was exchanged with the homologous gene of t...

journal_title：Vaccine

authors： de Smit AJ,Bouma A,van Gennip HG,de Kluijver EP,Moormann RJ

更新日期：2001-01-08 00:00:00

abstract：:The PEDVAC study is the first trial designed to analyze safety and immunogenicity of a therapeutic vaccination with a multiclade multigene HIV DNA vaccine (HIVIS) in infected children. Twenty HIV-1 vertically infected children (6-16 years of age), on stable antiretroviral treatment for at least 6 months with HIV-1 RNA...

journal_title：Vaccine

authors： Palma P,Romiti ML,Li Pira G,Montesano C,Mora N,Aquilani A,Santilli V,Tchidjou HK,Ivaldi F,Giovannelli L,Pontrelli G,Borra G,Blomberg P,Gudmundsdotter L,Bråve A,Montano M,Bernardi S,Manca F,Wahren B,Rossi P

更新日期：2011-09-09 00:00:00

abstract：:Haemagglutinin (HA), a mixture of haemagglutinin and neuraminidase (HA + NA), and matrix (M) protein were isolated from the influenza A virus and covalently coupled to a synthetic polyelectrolyte (P). A single injection into mice of the resultant conjugates (virogates) brought about efficient stimulation of the primar...

journal_title：Vaccine

authors： Petrov RV,Khaitov RM,Zhdanov VM,Sinyakov MS,Norimov ASh,Nekrasov AV,Podchernyaeva RYa,Kharitonenkov IG,Shchipanova MV

更新日期：1985-12-01 00:00:00