Abstract：
OBJECTIVE:Epidemiological and microbiological study of a salmonellosis outbreak, affecting 22 children in a nursery school in Oviedo (Spain). METHODS:Attack rates and epidemic curves were determined, and bacterial typing methods were applied. RESULTS:The outbreak was attributed to a Salmonella enterica serovar Typhimurium strain, belonging to an emergent type characterized by the presence of a hybrid virulence-resistance plasmid of 125-130 kb, named pUO-StVR2. The attack rate of confirmed cases vs. possible cases was 27.2% vs. 23.5% for the children and 0 vs. 26.5% for the staff of the affected center. The source of the infection could not be identified. Nevertheless, according to the evolution of the cases over time, the transmission route was likely to be personal contact between the staff and children, which facilitates fecal-oral dissemination. All but one of the 27 isolates analyzed (from 22 patients) showed identical features: R-profile, plasmid-profile, RAPD-type, PFGE-type; all were non-phage-typeable, with the exception of a DT104b isolate. pUO-StVR2 is probably a derivative of the virulence plasmid pSLT from the LT2 type strain that acquired an R-region complex (ACSSuT/blaOXA-catA1-strA/ B-aadA1-sul1-sul2-tet[B]), in which the blaOXA-aadA1 genes are part of the variable region of a class 1 integron. CONCLUSION:This outbreak is an example of how a Salmonella enterica serovar Typhimurium strain belonging to a type that is probably endemic in Spain can be transferred to the community and affect a susceptible population.
journal_name
Enferm Infecc Microbiol Clinjournal_title
Enfermedades infecciosas y microbiologia clinicaauthors
Bances M,Herrero A,González Y,Rodicio MR,González-Hevia MAdoi
10.1157/13106962subject
Has Abstractpub_date
2007-06-01 00:00:00pages
376-81issue
6eissn
0213-005Xissn
1578-1852pii
13106962journal_volume
25pub_type
杂志文章abstract：INTRODUCTION:Burkholderia cepacia (B. cepacia) complex is composed of 20 phylogenetically closely related bacterial species. Some species have emerged as opportunistic pathogens in immunocompromised patients and are responsible for nosocomial outbreaks. The B. cepacia complex is a recognized respiratory pathogen in pat...
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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doi：
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更新日期：1996-05-01 00:00:00
abstract：:The effectiveness of different methodologies to identify antigenemia and antibodies against HIV at the time of viral primary infection was evaluated. To this end, 6 consecutive serum samples of a patient who had had symptomatic seroconversion were assessed. The detection of antigenemia was earlier than that of antibod...
journal_title：Enfermedades infecciosas y microbiologia clinica
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doi：
更新日期：1990-08-01 00:00:00
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更新日期：2007-02-01 00:00:00
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journal_title：Enfermedades infecciosas y microbiologia clinica
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doi：
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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journal_title：Enfermedades infecciosas y microbiologia clinica
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