[Microbiological parameters of clinical interest in pulmonary infection in cystic fibrosis].

Abstract:

BACKGROUND:A 5-year study in patients with cystic fibrosis was carried out in order to gain a better understanding of the microbiological factors influencing clinical status and evolution. METHODS:Fifty-two patients were evaluated (mean age 16.6 years, range 0-36) during a 5 years-period (July 1988- July 1992). The clinical score of Shwachman and pulmonary function were evaluated at the beginning and at the end of the study period. Quantitative bacterial cultures were performed every 3 weeks recording the different colonical morphotypes of Pseudomonas aeruginosa. RESULTS:Beside the expected results regarding the prevalence of P. aeruginosa (80.7%) and Staphylococcus aureus (65.5%), a low rate of chronic infection with Burkholderia cepacia (1.9%) and high with S. maltophilia (9.6%) was found and it is worth noting the presence of Salmonella spp. in 3 patients. Microbial colonization followed the classical age-related sequence with 53.8% of patients older than 10 colonized with mucoid strains of P. aeruginosa. Colonization with mucoid Pseudomonas, increase in sputum bacterial counts and high diversity in colonizing morphotypes were parameters related with reduced clinical scores. CONCLUSIONS:The sequential study of the bacterial colonization in cystic fibrosis is important to follow the prognosis and evolution of the disease, and therefore, to choose the most effective therapy.

authors

Ballestero S,Escobar H,Suárez L,Baquero F

subject

Has Abstract

pub_date

1996-04-01 00:00:00

pages

245-9

issue

4

eissn

0213-005X

issn

1578-1852

journal_volume

14

pub_type

杂志文章
  • Microbiological diagnosis of infections caused by the genus Mycobacterium.

    abstract::Mycobacterial culture has a high sensitivity and is the test of choice for the microbiological diagnosis of tuberculosis and nontuberculous mycobacterial infections. However, the results of this culture require at least 2-3 weeks to obtain positivity. Staining is rapid and can be used as a complementary study, althoug...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2017.11.009

    authors: Samper S,González-Martin J

    更新日期:2018-02-01 00:00:00

  • Present epidemiology of tuberculosis. Prevention and control programs.

    abstract::Tuberculosis (TB) has affected humanity since the beginning of the recorded time and is associated with poverty, malnutrition, overcrowding, and immunosuppression. Since Koch discovered the infectious nature of the disease in 1882, knowledge about its history and physiopathology has advanced, but it continues to be a ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0213-005X(11)70011-8

    authors: Orcau À,Caylà JA,Martínez JA

    更新日期:2011-03-01 00:00:00

  • [Type 1 fimbriae and P fimbriae in E. coli producing chronic prostatitis].

    abstract::The fimbriated adhesines constitute a factor of virulence of E. coli in the urinary tract infections. The presence of type 1 fimbriae and fimbriae P was evaluated in 23 E. coli strains isolated with patients with chronic bacterial prostatitis. For the diagnosis of prostatitis the Stamey test was used. The detection of...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Andreu A,Fernández F,Banus JM

    更新日期:1989-03-01 00:00:00

  • [Role of the hospital environment and equipment in the transmission of nosocomial infections].

    abstract::The hospital environment is both a reservoir and source of infection for the hospital patient. Several areas around the patient should be considered: air, toilet water coming into contact with the patient, staff and medical devices, food, surfaces, and instruments contacting the patient's skin and mucosa, and sterile ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2013.10.004

    authors: López-Cerero L

    更新日期:2014-08-01 00:00:00

  • RDRioMycobacterium tuberculosis strains associated with isoniazid resistance in Northern Mexico.

    abstract:BACKGROUND:It has been established that the genomic background of Mycobacterium tuberculosis may influence disease progression, in particular for the Beijing family and the Latin American and Mediterranean (LAM)/RDRio strains. The purpose of this study was to evaluate the prevalence of the LAM/RDRio genotype in cases o...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2020.07.003

    authors: Bocanegra-García V,Cortez-de-la-Fuente LJ,Nakamura-López Y,González GM,Rivera G,Palma-Nicolás JP

    更新日期:2020-08-24 00:00:00

  • [Staphylococcus aureus nasal colonization in medical students: importance in nosocomial transmission].

    abstract:BACKGROUND:Staphylococcus aureus is the main pathogen causing nosocomial infections. Health professionals, including medical students, could be a source of transmission. The aims of the study were to determine the rate of nasal carriage of S.aureus susceptible and resistant to methicillin (MRSA) and evaluate the knowle...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2012.12.005

    authors: López-Aguilera S,Goñi-Yeste Mdel M,Barrado L,González-Rodríguez-Salinas MC,Otero JR,Chaves F

    更新日期:2013-10-01 00:00:00

  • [Association between genotype screening results obtained by PFGE and PCR for hypervariable regions of the mecA gene in methicillin-resistant Staphylococcus aureus].

    abstract:INTRODUCTION:The emergence of methicillin-resistant Staphylococcus aureus (MRSA) has become a major epidemiological problem worldwide. METHODS:We determined the degree of association between the genotype screening results obtained by pulse-field gel electrophoresis (PFGE) and polymerase chain reaction (PCR) for 7 hype...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2008.08.001

    authors: Medina G,Otth C,Araya P,Hormazabal JC,Fernández J,Maldonado A,Fernández H,Otth L,Wilson M

    更新日期:2009-04-01 00:00:00

  • [Subacute endocarditis caused by Actinobacillus actinomycetemcomitans].

    abstract:BACKGROUND:We describe the cases of endocarditis caused by Actinobacillus actinomycetemcomitans (EAA) observed at our hospital. PATIENTS AND METHODS:We revised clinical records and microbiological documents from patients admitted at our hospital, with A. actinomycetemcomitans in blood cultures occurred from 1972-1998....

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Belloch SL,Salavert M,Lacruz J,López-Aldeguer J,Pérez-Bellés C

    更新日期:2000-10-01 00:00:00

  • Using mobile applications and websites for the diagnosis of COVID-19 in Spain.

    abstract:INTRODUCTION:New tools are needed for early evaluation of patients who could be infected by COVID-19 during this pandemic. M-Health (apps) could be a solution in this setting to evaluate a COVID-19 diagnosis. The aim of this study was to describe which COVID-19s apps are available in Spain. METHODS:We made a review of...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2020.08.002

    authors: Guisado-Clavero M,Ares-Blanco S,Ben Abdellah LD

    更新日期:2020-09-09 00:00:00

  • [Evaluation of the bone marrow in patients with brucellosis. Clinico-pathological correlation].

    abstract::In the present study the 60 patients with brucellosis and evaluation of bone marrow aspirate seen at the Hospital Base Cayetano Heredia from 1980 to 1986 were included. Iron deficiency was found in the bone marrow in 34.5% of patients, 31% in males and 36% in females. No correlation was found between iron deficiency a...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: García P,Yrivarren JL,Argumans C,Crosby E,Carrillo C,Gotuzzo E

    更新日期:1990-01-01 00:00:00

  • Current situation in the development of a preventive HIV vaccine.

    abstract::The uncontrolled progression of the AIDS epidemic has made the development of an efficacious human immunodeficiency virus (HIV) vaccine a major objective of scientific research. No effective preventive vaccine against HIV is currently available and sterilizing immunity has not yet been achieved in animal models. This ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Alcamí J,Joseph Munné J,Muñoz-Fernández MA,Esteban M

    更新日期:2005-07-01 00:00:00

  • Experience in the use of dalbavancin in diabetic foot infection.

    abstract:OBJECTIVE:To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital. METHODS:A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hos...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2020.11.013

    authors: Navarro-Jiménez G,Fuentes-Santos C,Moreno-Núñez L,Alfayate-García J,Campelo-Gutierrez C,Sanz-Márquez S,Pérez-Fernández E,Velasco-Arribas M,Hervás-Gómez R,Martín-Segarra O,Losa-García JE

    更新日期:2021-01-12 00:00:00

  • Persistence of a ST6 clone of Enterococcus faecalis genotype vanB2 in two Hospitals in Aragon (Spain).

    abstract:INTRODUCTION:In order to study the evolution of the outbreak that occurred between 2009 and 2010 in 3 hospitals in Zaragoza, all vancomycin-resistant clinical Enterococcus faecalis isolates identified between 2011 and 2013 at these hospitals were characterised. METHODS:Molecular characterisation of the isolates and an...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.eimc.2016.02.020

    authors: Alonso CA,Rezusta A,Seral C,Ferrer I,Castillo FJ,Torres C

    更新日期:2017-11-01 00:00:00

  • [Epidemiology and clinical features of Streptococcus pyogenes bacteremia in Cartagena (Murcia, Spain)].

    abstract:INTRODUCTION:A gradual increase in severe cases due to Streptococcus pyogenes or Streptococcus beta-hemolytic group A (SGA), has been detected in the last few decades. METHODS:Retrospective study of bacteremia due to S.pyogenes detected between January 2009 and January 2013 in Cartagena. The annual incidence for sever...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2013.01.010

    authors: Jimeno-Almazán A,Viqueira-Gonzalez M,Alcalde Mdel M,Alcaraz-Vidal B,Vera-Méndez F

    更新日期:2013-08-01 00:00:00

  • Antibiotic resistance patterns of Acinetobacter calcoaceticus-A. baumannii complex species from Colombian hospitals.

    abstract:INTRODUCTION:Only automated phenotypic methods are currently used in Colombian hospitals for identifying isolates of the Acinetobacter calcoaceticus-A. baumannii complex (ACB). The phenotypical similarities in these species mean that they cannot be differentiated by manual or automated methods, thereby leading to their...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2012.07.013

    authors: Reguero MT,Medina OE,Hernández MA,Flórez DV,Valenzuela EM,Mantilla JR

    更新日期:2013-03-01 00:00:00

  • Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions.

    abstract:INTRODUCTION:the duration adequacy of antibiotic regimens is one of the key points of Antimicrobial Stewardship Programs (ASP) given the relationship between the risk of resistance and days of exposure to antimicrobials. METHODS:monitoring activities of intravenous antibiotics longer than 7 days at Hospital Infantil V...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2020.02.015

    authors: Melendo S,Fernández-Polo A,Castellnou Asens I,Mendoza-Palomar N,Barnés-Mayolas M,Soler-Palacín P,Grupo PROA-NEN.,Miembros del Grupo PROA-NEN.

    更新日期:2020-03-27 00:00:00

  • [Primary care doctors attitudes and practices in the diagnosis of HIV infection].

    abstract:OBJECTIVE:To explore the attitudes and practices of Primary Health Care professionals in the diagnosis of HIV infection according to current protocols and the degree of acceptance of simplified HIV testing (without a separate written consent and without asking about risk practices). MATERIAL AND METHODS:An observation...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2011.02.014

    authors: Busto MJ,García San Miguel L,Castelao ME,Bermúdez E

    更新日期:2011-08-01 00:00:00

  • [Q fever in Gran Canaria: 40 new cases].

    abstract:INTRODUCTION:The aim of this study was to describe the clinical and epidemiologic features of Q fever in the southern area of the island of Gran Canaria (Spain). METHODS:We conducted a retrospective analysis of the clinical and epidemiological data of the cases of Q fever diagnosed by the Microbiology Laboratory of th...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/s0213-005x(03)72869-9

    authors: Bolaños M,Santana OE,Pérez-Arellano JL,Angel-Moreno A,Moreno G,Burgazzoli JL,Martín-Sánchez AM

    更新日期:2003-01-01 00:00:00

  • [Glycopeptide-resistant Enterococcus faecium. Analysis of the resistance genotype, virulence and genetic lines].

    abstract:OBJECTIVE:The objective of this study was to analyse the genotypic characteristics of all Enterococcus isolates with acquired vancomycin resistance (VRE) recovered in the Hospital Clinic (Barcelona, Spain) in a period of three years and two months. METHODS:All VRE isolated in the referred Hospital in the period Januar...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2012.05.010

    authors: López M,Alvarez-Martínez MJ,Marco F,Torres C

    更新日期:2013-01-01 00:00:00

  • [Prevalence of hepatitis virus infection markers in HIV-infected patients in Southern Spain].

    abstract:OBJECTIVES:To determine: (a) The prevalence of active infection by the hepatitis C virus (HCV) and hepatitis B virus (HBV) in HIV-infected patients, as well as previous exposure to hepatitis A virus (HAV), HBV and HCV. (b) The proportion of patients who have been vaccinated against HAV and/or HBV. (c) The HCV genotype ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2011.12.008

    authors: Cifuentes C,Mira JA,Vargas J,Neukam K,Escassi C,García-Rey S,Gilabert I,González-Monclova M,Bernal S,Pineda JA

    更新日期:2012-10-01 00:00:00

  • [Colonization by Streptococcus group B in full term pregnancy and newborns in a community in Venezuela].

    abstract:BACKGROUND:The aim of this study was to define the incidence of cervico-vaginal colonization by group B Streptococcus (SGB) in full term pregnancy as well as vertical and horizontal transmission in newborns attended in two public hospitals in Valencia, Venezuela. METHODS:An study cervico-vaginal exudates from 171 full...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Riera L,Benavides G,Morillo N

    更新日期:1993-06-01 00:00:00

  • [Microbiological profile of acute viral gastroenteritis attended in a paediatric department of an area with high vaccine cover against rotavirus].

    abstract:INTRODUCTION:Vaccination against rotavirus has led to a significant decline of the disease. The aim of the present work is to evaluate the clinical and epidemiological features of the viral acute gastroenteritis (AGE) in an area with high immunization coverage against rotavirus. METHOD:A prospective microbiological ev...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2013.09.008

    authors: García-Magán C,de Castro-López MJ,Llovo-Taboada J,Curros-Novo C,Puente-Puig M,Sánchez-Fauquier A,Martinón-Torres F

    更新日期:2014-04-01 00:00:00

  • [General concepts and study methods in pharmacogenetics].

    abstract::Pharmacogenetics, the study of how individual genetic profiles influence the response to drugs, is an important topic. Results from pharmacogenetics studies in various clinical settings may lead to personalized medicine. Herein, we present the most important concepts of this discipline, as well as currently-used study...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/s0213-005x(08)76506-6

    authors: Lubomirov R,Telenti A,Rotger M

    更新日期:2008-05-01 00:00:00

  • [HIV infection and other sexually-transmitted infections among immigrants in Barcelona].

    abstract:BACKGROUND:Immigration is a recent phenomenon in Spain. Certain subgroups of the immigrant population may be vulnerable to acquiring sexually transmitted infections (STI). MATERIAL AND METHODS:Descriptive study of the seroprevalenceof certain STI (HIV, hepatitis B and syphilis) and the general characteristicsn of pers...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/s0213-005x(02)72777-8

    authors: Vall Mayans M,Arellano E,Armengol P,Escribà JM,Loureiro E,Saladié P,Sanz B,Saravanya M,Vall M,Villena MJ

    更新日期:2002-04-01 00:00:00

  • Update on bacteraemia in oncology and hematology.

    abstract::The present article is an update of the literature on bacteraemia in onco-hematologic patients. A multidisciplinary group of Spanish physicians with an interest in this field selected the most important papers published recently. Papers from the fields of basic science, epidemiology, causative microorganisms and clini...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0213-005X(11)70036-2

    authors: Fortún J,Sanz MÁ,Madero L,López J,de la Torre J,Jarque I,Vallejo C

    更新日期:2011-03-01 00:00:00

  • [Antibiotic ointments and methicillin-resistant Staphylococcus aureus with a reservoir in a healthcare worker in a tertiary hospital].

    abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) has become an important hospital-acquired pathogen, with transfer of the organism from a carrier or infected patient to uninfected patients by the hands or clothing of staff as the main mode of transmission. METHODS:Investigation of a cluster of new cases o...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2012.10.002

    authors: Molina-Cabrillana J,Del Rosario-Quintana C,Tosco-Núñez T,Dorta-Hung E,Quori A,Martín-Sánchez AM

    更新日期:2013-10-01 00:00:00

  • Streptococcus suis spondylodiscitis: 2 new cases and a literature review.

    abstract:INTRODUCTION:Streptococcus suis (S. suis) infection is poorly described zoonosis in our country, which is related with exposure to pigs or their meat. The most common clinical presentation is meningitis, while spinés involvement is rare. METHODS:We report 2 cases of S. suis infection and perform a systematic review of...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2020.08.005

    authors: Romay-Lema EM,Ventura-Valcárcel P,Iñiguez-Vázquez I,García-Pais MJ,García-Garrote F,Rabuñal-Rey R,Alonso MP,Corredoira-Sánchez J

    更新日期:2020-10-14 00:00:00

  • [Comparative study of three culture media for detecting group B Streptococcus colonization in pregnant women].

    abstract:OBJECTIVE:To compare the efficacy of three culture media to detect vaginal and rectal colonization by group B streptococci (GBS) in pregnant women. METHODS:We processed 1334 samples from 861 pregnant women: in 388 patients only vaginal swab was cultured (Group A) and in 473 vaginal and rectal swabs were cultured (Grou...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/s0213-005x(03)72961-9

    authors: Bosch-Mestres J,Martín-Fernández RM,Jiménez de Anta-Losada MT

    更新日期:2003-08-01 00:00:00

  • Time to positivity of blood cultures in patients with bloodstream infections: A useful prognostic tool.

    abstract:OBJECTIVE:The time to positivity (TTP) of blood cultures in patients with bloodstream infections (BSIs) has been considered to be a possible prognostic tool for some bacterial species. However, notable differences have been found between sampling designs and statistical methods in published studies to date, which makes...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2016.10.003

    authors: Martín-Gutiérrez G,Martín-Pérez C,Gutiérrez-Pizarraya A,Lepe JA,Cisneros JM,Aznar J

    更新日期:2017-12-01 00:00:00

  • Reliable detection of St. Louis encephalitis virus by RT-nested PCR.

    abstract:INTRODUCTION:St. Louis encephalitis virus (SLEV) is a re-emerging arbovirus in South America, with reported cases in humans in Argentina and Brazil. This fact indicates that there is an urgent need to increase the current knowledge about this virus in order to control and prevent future cases. Exhaustive epidemiologica...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1157/13114389

    authors: Ré V,Spinsanti L,Farías A,Díaz A,Vázquez A,Aguilar J,Tenorio A,Contigiani M

    更新日期:2008-01-01 00:00:00