当前位置： SCI文献检索 > ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA期刊下所有文献 > [Associated factors and descriptive analysis of healthcare-related infective endocarditis in a tertiary reference hospital].

[Associated factors and descriptive analysis of healthcare-related infective endocarditis in a tertiary reference hospital].

Abstract：

INTRODUCTION AND OBJECTIVES:The primary aim of this study was to evaluate associated factors, clinical features and prognosis of healthcare-related infective endocarditis cases compared with community-acquired and intravenous drug user-related episodes. Changes in the distribution of healthcare-related infective endocarditis were also analysed over time in our setting. METHODS:A prospective, observational, comparative study was performed. We included all the cases of infective endocarditis from January 2003 to June 2010, which were then classified into 2 groups: group 1: community-acquired and intravenous drug user origin, and group 2: nosocomial and non-nosocomial healthcare-related cases. The episodes were classified into 2 periods: period I: January/2003-June/2006 and period II: July/2006-June 2010. Univariate and multivariate analyses were performed. RESULTS:A total of 212 cases were included (group 1: 138, group 2: 74). The variables of age (risk ratio 1.026; 95%CI, 1.003 to 1.049), Charlson index (risk radio 1.242; 95%CI, 1.067 to 1.445), and previous heart surgery (risk ratio 2.522; 95%CI, 1.353 to 4.701) were independently associated with healthcare-related infective endocarditis on multivariate analysis. A non-significant increase was observed in healthcare-related cases of infective endocarditis in period II (40/104; 38.4% vs. 34/108; 31.4%). CONCLUSIONS:The recent increase in healthcare-related infective endocarditis seems to be associated with the use of invasive procedures in elderly patients with prosthetic cardiac valve, and those with a greater number of underlying diseases, especially patients with chronic renal failure on haemodialysis.

journal_name

Enferm Infecc Microbiol Clin

journal_title

Enfermedades infecciosas y microbiologia clinica

authors

Núñez Aragón R,Pedro-Botet Montoya ML,Mateu Pruñonosa L,Vallejo Camazón N,Sopena Galindo N,Casas García I,Molinos Arbós S,Sabrià Leal M

doi

10.1016/j.eimc.2012.03.014

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

15-22

issue

1

eissn

0213-005X

issn

1578-1852

pii

S0213-005X(12)00167-X

journal_volume

31

pub_type

杂志文章

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