Abstract：
BACKGROUND:Fecal colonization by multiresistant bacteria can be a source of nosocomial infections. The aim of this work was to study fecal colonization by Klebsiella pneumoniae in neonatal intensive care unit (NICU) patients and investigate the resistance profiles of the strains. METHODS:From May to October 2001, 11 stool specimens were collected from each patient hospitalized in the NICU during this period (425 specimens). Antimicrobial susceptibility was determined in K. pneumoniae isolates, and 30 strains resistant to third-generation cephalosporins were tested by polymerase chain reaction (PCR) to detect the blaCTX-M-2 gene. RESULTS:K. pneumoniae grew in the 66% of the samples. Extended-spectrum b-lactamases (ESBL) were detected in 82.5% of these strains (ESBL-K. pneumoniae), 54.3% of all the strains studied. Among the neonates colonized by ESBL-K. pneumoniae (56% of patients), significant differences in colonization rates were observed according to gestational age, but not according to the mode of delivery or sex. ESBL-K. pneumoniae strains showed a high frequency of gentamicin resistance (97.3%) and amikacin resistance (71.4%). Nevertheless, they were all susceptible to cefoxitin and imipenem, and more than 90% were also susceptible to ciprofloxacin and piperacillin-tazobactam. In all the cefotaxime-resistant strains, an amplicon consistent with a CTX-M-type beta -lactamase was found by PCR. CONCLUSION:A high percentage of NICU patients were colonized with ESBL-K. pneumoniae strains belonging to the CTX-M family, with elevated rates of aminoglycoside resistance. Gestational age was the only variable associated with significant differences in colonization rates.
journal_name
Enferm Infecc Microbiol Clinjournal_title
Enfermedades infecciosas y microbiologia clinicaauthors
Desimoni MC,Esquivel GP,Merino LAdoi
10.1157/13067617subject
Has Abstractpub_date
2004-11-01 00:00:00pages
507-11issue
9eissn
0213-005Xissn
1578-1852pii
13067617journal_volume
22pub_type
杂志文章abstract：:Chronic hepatitis B continues to be a serious problem worldwide. Because a high viral load is associated with greater progression to cirrhosis and hepatocarcinoma in these patients, new drugs that achieve rapid, potent and lasting suppression of viral replication must be sought. Entecavir is a new, highly potent antiv...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/s0213-005x(08)76518-2
更新日期：2008-05-01 00:00:00
abstract：:We analyze the experience in serologic diagnosis of Lyme's borreliosis. From a total of 551 patients studied from 1987 to 1989, we further evaluate 80 cases with erythema chronicum migrans or a clinical diagnosis of Lyme's disease and positive serological tests. The techniques used were IFI, ELISA1 (Whittaker Bioprodu...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:Atazanavir (ATV) is an HIV protease inhibitor (IP) with a high in vitro activity against HIV-1, that demonstrates a high additive activity in the presence of other antiretrovirals and a synergic activity with other PI. Oral absorption is greater than 68%, maximum concentration (C(max)) being reached approximately 2 to...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/S0213-005X(08)76613-8
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Several recent studies have shown that the combination of ddI plus TDF can produce an unexpected drop in CD4 cell counts, even after correcting the ddI dose. OBJECTIVE:Comparative study of the immunological effectiveness of various once-daily NRTI backbones (ddI plus TDF, ddI plus 3TC or TDF plus 3TC) in an...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1157/13091779
更新日期：2006-08-01 00:00:00
abstract：BACKGROUND:There is little information regarding peripheral facial palsy (PFP) as a complication of varicella. We describe 2 adults who developed varicella-related PFP, in 1 case as a part of Guillain-Barré syndrome (GBS), and review all reported cases of this condition. METHODS:MEDLINE search. RESULTS:A total of 10 ...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/j.eimc.2009.09.009
更新日期：2010-10-01 00:00:00
abstract：:This review offers succinct, precise, and complete information based on the available data concerning new anaerobic bacterial species involved in infectious diseases in humans. All hitherto undescribed species, those not previously implicated in clinical conditions, those with confirmed implication in human disease th...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/j.eimc.2008.09.015
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Diarrhea associated with Clostridium difficile is a health care problem of growing importance in the last few years specially in the hospital environment. The epidemiologic data and factors associated with this disease have not, to date, been sufficiently studied in Spain. METHODS:The cases of diarrhea asso...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:Streptococcus agalactiae is a well-recognized pathogen in the obstetric population and is a cause of invasive infection in adults with underlying diseases. Nevertheless, the role of S. agalactiae in urinary tract infections in the adult non-pregnant population treated in outpatient health care centers has ...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/s0213-005x(04)73040-2
更新日期：2004-02-01 00:00:00
abstract：:The pathogenesis of arteriosclerosis in HIV-infected patients is complex. Both patient-related cardiovascular risk factors (CVRF) established for the general population and those related to highly-active antiretroviral therapy (HAART) and HIV infection per se are involved. Some traditional CVRF are more frequent in HI...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/S0213-005X(09)73440-8
更新日期：2009-09-01 00:00:00
abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly common cause of hospital acquired pneumonia (HAP) and the second most frequently isolated pathogen from patients who die from HAP. High-risk units for MRSA colonization such as intensive care (ICU's) are the most affected. Multiple risk factors for ...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1157/13091219
更新日期：2005-12-01 00:00:00
abstract：INTRODUCTION:St. Louis encephalitis virus (SLEV) is a re-emerging arbovirus in South America, with reported cases in humans in Argentina and Brazil. This fact indicates that there is an urgent need to increase the current knowledge about this virus in order to control and prevent future cases. Exhaustive epidemiologica...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1157/13114389
更新日期：2008-01-01 00:00:00
abstract：:The evolution of antimicrobial susceptibility of Bacteroides fragilis over a five year period is described. We have studied 30 selected strains isolated each year at the University Hospital of Sevilla (total: 150 strains). We did not find any resistant strain to chloramphenicol, metronidazole or imipenem. Resistance t...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：INTRODUCTION:The increase in infections due to dermatophytes in recent years led us to study the effectiveness of new antifungal formulations against these microorganisms. METHODS:The in vitro activity of a new antifungal agent, voriconazole, was compared with three other antifungal agents, itraconazole, fluconazole a...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/s0213-005x(03)72992-9
更新日期：2003-11-01 00:00:00
abstract：:The results of the study of 117 outbreaks of food poisoning in the Basque Autonomous Community during 1984-1986 are reported. In 76% of these outbreaks the causative agent could be isolated. Bacteria of the genus Salmonella accounted for 86.5% of the outbreaks with a known etiology, S. enteritidis being the most commo...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：
更新日期：1989-12-01 00:00:00
abstract：OBJECTIVE:To update antiretroviral recommendations in antiretroviral therapy (ART) in HIV-infected children and adolescents. METHODS:Theses guidelines have been formulated by a panel of members of the Plan Nacional sobre el SIDA (PNS) and the Asociacion Espanola de Pediatria (AEP) by reviewing the current available ev...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 共识发展会议,杂志文章,评审
doi：10.1157/13074970
更新日期：2005-05-01 00:00:00
abstract：:The anaerobic bacteria resistance to antibiotics is increasing, and even has appeared against the most active of those, like metronidazol and carbapenems. This fact forces to make and periodical sensibility tests -at least in the most aggressive and virulent species, in cases that they are isolated from life locations...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/S0213-005X(14)70146-6
更新日期：2014-02-01 00:00:00
abstract：:An outbreak of S.Typhimurium occurred in several towns and cities in the province of Castellon (Spain) between 23 February and 27 May 2011. On April 5, the microbiology laboratory of a hospital in Castellon alerted the health authorities to the increase in S.Typhimurium isolated in fecal culture of children with gastr...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2015.11.016
更新日期：2016-11-01 00:00:00
abstract：:The development of an antimicrobial stewardship program (ASP) requires institutional support. However, obtaining sufficient institutional support is often a complex task that requires convincing the hospital's managers of the benefits of these programs. Additionally, in the design and implementation of an ASP, antimic...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/S0213-005X(13)70133-2
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:We describe the cases of endocarditis caused by Actinobacillus actinomycetemcomitans (EAA) observed at our hospital. PATIENTS AND METHODS:We revised clinical records and microbiological documents from patients admitted at our hospital, with A. actinomycetemcomitans in blood cultures occurred from 1972-1998....
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy of three culture media to detect vaginal and rectal colonization by group B streptococci (GBS) in pregnant women. METHODS:We processed 1334 samples from 861 pregnant women: in 388 patients only vaginal swab was cultured (Group A) and in 473 vaginal and rectal swabs were cultured (Grou...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/s0213-005x(03)72961-9
更新日期：2003-08-01 00:00:00
abstract：:New drugs will soon be incorporated into the echinocandin class of antifungals. The first to be released on to the market will be anidulafungin. The pharmacokinetic characteristics of this drug clearly distinguish it from the only representative of this family of antifungal agents available to date: caspofungin. Speci...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/s0213-005x(08)76588-1
更新日期：2008-12-01 00:00:00
abstract：INTRODUCTION:Nosocomial fungal infections have increased significantly in the last decade. Candida detection in clinical specimens can mean either colonization or an infection which can be local (muguet) or invasive. Knowledge of the species helps in choosing the best treatment. The aims of this study were to determine...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2012.09.011
更新日期：2013-06-01 00:00:00
abstract：:Monotherapy with LPV/r maintains blocked viral replication when used as a simplification strategy from antiretroviral therapy with a boosted protease inhibitor and two nucleoside analogs in patients with an undetectable viral load for at least 6 months. This simplification strategy can be recommended to patients in th...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/s0213-005x(08)76606-0
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:It has been established that the genomic background of Mycobacterium tuberculosis may influence disease progression, in particular for the Beijing family and the Latin American and Mediterranean (LAM)/RDRio strains. The purpose of this study was to evaluate the prevalence of the LAM/RDRio genotype in cases o...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2020.07.003
更新日期：2020-08-24 00:00:00
abstract：INTRODUCTION:Invasive pneumococcal disease (IPD) typically presents as bacterial pneumonia, meningitis or primary bacteraemia. However, Streptococcus pneumoniae can produce infection at any level of the body (endocarditis, arthritis, spontaneous bacterial peritonitis, etc.), which is also known as unusual IPD (uIPD). T...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2017.05.003
更新日期：2018-05-01 00:00:00
abstract：:The disadvantages of the long-term administration of antiretroviral therapy as well as the huge number of affected persons have placed the cure of HIV as a primary goal of Public Health. HIV may persist in the organism by at least four mechanisms: a latently infected cellular reservoir, the persistent replication of H...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：10.1016/j.eimc.2018.01.007
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:HIV infection and parenteral drug abuse (PDA) are frequently associated conditions. Both are at increased risk of developing specific types of Candida infections. Localized CNS infection is an exceptional finding. METHODS:We report two cases of meningitis in PDA due to Candida albicans--one of them HIV posi...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章,评审
doi：
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Enteroviruses (EV) are the main aetiological agents of aseptic meningitis in children and a common cause of febrile illnesses in young infants in summer. A rapid diagnosis is essential to rule out other conditions. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay performed in cerebros...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2012.07.007
更新日期：2013-02-01 00:00:00
abstract：INTRODUCTION:Zika virus is mainly transmitted through the bites of infected Aedes mosquitoes, although mother-to-child and sexual transmission have also been described. The presence of Zika virus in semen after infection seems to be not uncommon, but the duration of viral persistence has not been well-determined. METH...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2016.10.009
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Vaccination against rotavirus has led to a significant decline of the disease. The aim of the present work is to evaluate the clinical and epidemiological features of the viral acute gastroenteritis (AGE) in an area with high immunization coverage against rotavirus. METHOD:A prospective microbiological ev...
journal_title：Enfermedades infecciosas y microbiologia clinica
pub_type： 杂志文章
doi：10.1016/j.eimc.2013.09.008
更新日期：2014-04-01 00:00:00
