当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.

Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.

Abstract：

:Autophagy is the bulk degradation of cytosolic materials in lysosomes/vacuoles of eukaryotic cells. In the yeast Saccharomyces cerevisiae, 17 Atg proteins are known to be involved in autophagosome formation. Genome wide analyses have shown that Atg17 interacts with numerous proteins. Further studies on these interacting proteins may provide further insights into membrane dynamics during autophagy. Here, we identify Cis1/Atg31 as a protein that exhibits similar phenotypes to Atg17. ATG31 null cells were defective in autophagy and lost viability under starvation conditions. Localization of Atg31 to pre-autophagosomal structures (PAS) was dependent on Atg17. Coimmunoprecipitation experiments indicated that Atg31 interacts with Atg17. Together, Atg31 is a novel protein that, in concert with Atg17, is required for proper autophagosome formation.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Kabeya Y,Kawamata T,Suzuki K,Ohsumi Y

doi

10.1016/j.bbrc.2007.02.150

subject

Has Abstract

pub_date

2007-05-04 00:00:00

pages

405-10

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(07)00437-8

journal_volume

356

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Activation mechanism of HSP16.5 from Methanococcus jannaschii.

    abstract：:The small heat shock proteins are the ubiquitous proteins found in a wide range of organisms and function as molecular chaperones by binding to the folding intermediates of their substrates. Although the crystal structure of HSP16.5, a small heat shock protein from Methanococcus jannaschii, revealed that it is a hollo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)01302-0

    authors： Kim DR,Lee I,Ha SC,Kim KK

    更新日期：2003-08-08 00:00:00

  • Hydrolysis of oxidized nucleotides by the Escherichia coli Orf135 protein.

    abstract：:To examine the possibility that the Orf135 protein of Escherichia coli functions as a hydrolyzing enzyme for a damaged DNA precursor (deoxyribonucleoside 5'-triphosphate), we purified the recombinant Orf135 protein and incubated it with oxidized deoxynucleotides. Of the nucleotides tested, 2-hydroxydeoxyadenosine 5'-t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5781

    authors： Kamiya H,Murata-Kamiya N,Iida E,Harashima H

    更新日期：2001-11-02 00:00:00

  • Adrenodoxin supports reactions catalyzed by microsomal steroidogenic cytochrome P450s.

    abstract：:The interaction of adrenodoxin (Adx) and NADPH cytochrome P450 reductase (CPR) with human microsomal steroidogenic cytochrome P450s was studied. It is found that Adx, mitochondrial electron transfer protein, is able to support reactions catalyzed by human microsomal P450s: full length CYP17, truncated CYP17, and trunc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.12.047

    authors： Pechurskaya TA,Harnastai IN,Grabovec IP,Gilep AA,Usanov SA

    更新日期：2007-02-16 00:00:00

  • Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonica.

    abstract：:Sensitization to Cupressaceae pollen has become one of the most important causes of pollinosis in Western countries during winter and early spring. However, the characterization of the extracts, the allergens involved and the cross-reactivity with other pollen sources still remain poorly studied; in the case of Cupres...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.09.079

    authors： Pico de Coaña Y,Parody N,Fuertes MÁ,Carnés J,Roncarolo D,Ariano R,Sastre J,Mistrello G,Alonso C

    更新日期：2010-10-22 00:00:00

  • High-active truncated luciferase of copepod Metridia longa.

    abstract：:The technology of real-time imaging in living cells is crucial for understanding of intracellular events. For this purpose, bioluminescent reporters have been introduced as sensitive and convenient tools. Metridia luciferase (MLuc) from the copepod Metridia longa is a coelenterazine-dependent luciferase containing a n...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.11.063

    authors： Markova SV,Burakova LP,Vysotski ES

    更新日期：2012-01-06 00:00:00

  • Toxoplasma gondii exposes phosphatidylserine inducing a TGF-beta1 autocrine effect orchestrating macrophage evasion.

    abstract：:Toxoplasmosis is a worldwide disease caused by Toxoplasma gondii. Activated macrophages control T. gondii growth by nitric oxide (NO) production. However, T. gondii active invasion inhibits NO production, allowing parasite persistence. Here we show that the mechanism used by T. gondii to inhibit NO production persisti...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.09.114

    authors： Seabra SH,de Souza W,Damatta RA

    更新日期：2004-11-12 00:00:00

  • Genistein, a tyrosine kinase inhibitor, blocks the cell cycle progression but not Ca2+ influx induced by BAY K8644 in FRTL-5 cells.

    abstract：:IGF-I, when added to TSH-primed FRTL-5 cells, induces a long lasting Ca2+ influx and then DNA synthesis. Ca2+ channel agonist, BAYK 8644, is capable to mimic these effects on cell proliferation. We studied the effect of genistein, a specific tyrosine kinase inhibitor, on BAY K8644- or IGF-I- induced cell cycle progres...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1120

    authors： Takano T,Takada K,Tada H,Nishiyama S,Amino N

    更新日期：1993-02-15 00:00:00

  • Epimorphin is involved in differentiation of rat hepatic stem-like cells through cell-cell contact.

    abstract：:Epimorphin, a mesenchymal cell surface-associated molecule, is detected on hepatic stellate cells (HSCs) in the liver. Here, we show the involvement of epimorphin in differentiation of rat hepatic stem-like cells (HSLCs) through contact with HSCs. HSLCs, isolated from adult rats, cultured in stellate cell-conditioned ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.09.225

    authors： Miura K,Nagai H,Ueno Y,Goto T,Mikami K,Nakane K,Yoneyama K,Watanabe D,Terada K,Sugiyama T,Imai K,Senoo H,Watanabe S

    更新日期：2003-11-14 00:00:00

  • PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs.

    abstract：:PES1 (also known as Pescadillo), a nucleolar protein, was involved in biogenesis of ribosomal RNA. Up-regulation of PES1 has been documented in some human cancers, indicating that PES1 may play some crucial roles in tumorigenesis. In our previous study, it was found that silencing of PES1 resulted in decreased prolife...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.12.145

    authors： Xie W,Qu L,Meng L,Liu C,Wu J,Shou C

    更新日期：2013-02-15 00:00:00

  • Characterization of homo-oligomeric complexes of alpha and beta chaperonin subunits from the acidothermophilic archaeon, Sulfolobus sp. strain 7.

    abstract：:The chaperonin from the acidothermophilic archaeon, Sulfolobus sp. Strain 7, is composed of two kinds of subunits designated as Scp alpha and Scp beta. In this study, we characterized the recombinant Scp alpha and Scp beta, which were separately expressed in Escherichia coli. Both of them were able to assemble to homo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.8026

    authors： Yoshida T,Yohda M,Suzuki M,Yazaki K,Miura K,Endo I

    更新日期：1998-01-26 00:00:00

  • Treadmill running attenuates neonatal hypoxia induced adult depressive symptoms and promoted hippocampal neural stem cell differentiation via modulating AMPK-mediated mitochondrial functions.

    abstract：:Neonatal hypoxia can induce the persisting brain dysfunctions and subsequently result in the behavioral abnormalities in adulthood. Improving mitochondrial functions were suggested as the effective strategy for brain functional recovery. In this study, we tested the effects of physical exercise, a well-established way...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.12.036

    authors： Sun L,Ye R,Liang R,Xing F

    更新日期：2020-03-05 00:00:00

  • Augmentation of obese (ob) gene expression and leptin secretion in obese spontaneously hypertensive rats (obese SHR or Koletsky rats).

    abstract：:To explore the pathophysiologic roles of the obese (ob) gene product, leptin, in the development of obesity and hypertension, we examined ob gene expression and leptin secretion in obese spontaneously hypertensive rats (obese SHR or Koletsky rats) at the stage of established obesity and hypertension. Expression of the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.6145

    authors： Hiraoka J,Hosoda K,Ogawa Y,Ikeda K,Nara Y,Masuzaki H,Takaya K,Nakagawa K,Mashimo T,Sawamura M,Koletsky RJ,Yamori Y,Nakao K

    更新日期：1997-02-24 00:00:00

  • Hepatocyte growth factor increases mitochondrial mass in glioblastoma cells.

    abstract：:Hepatocyte growth factor/scatter factor (HGF) is a multifunctional growth factor that is linked to the initiation and/or progression of numerous malignancies. HGF also alters cancer cell responses to DNA damaging cytotoxic agents. Many cell responses to Met activation require alterations in metabolic activity but how ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.05.064

    authors： Xia S,Laterra J

    更新日期：2006-07-14 00:00:00

  • Eupatilin, an activator of PPARα, inhibits the development of oxazolone-induced atopic dermatitis symptoms in Balb/c mice.

    abstract：:Eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone) is the main lipophilic flavonoid obtained from the Artemisia species. Eupatilin has been reported to have anti-apoptotic, anti-oxidative and anti-inflammatory activities. Previously, we found that eupatilin increases transcriptional activity and expression of peroxis...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.01.098

    authors： Jung Y,Kim JC,Park NJ,Bong SK,Lee S,Jegal H,Jin LT,Kim SM,Kim YK,Kim SN

    更新日期：2018-02-05 00:00:00

  • The octamer motif present in the Rex-1 promoter binds Oct-1 and Oct-3 expressed by EC cells and ES cells.

    abstract：:Rex-1 is a zinc finger-containing gene that is expressed in embryonal carcinoma (EC) cells and embryonic stem (ES) cells. Upon differentiation with retinoic acid (RA), transcription of the Rex-1 gene decreases rapidly. Analysis of the 5'-flanking region of the Rex-1 gene identified a consensus motif for the octamer fa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2395

    authors： Rosfjord E,Rizzino A

    更新日期：1994-09-30 00:00:00

  • Differential expression of the transcription factor NF-kappaB during human mononuclear phagocyte differentiation to macrophages and dendritic cells.

    abstract：:An important role for the Rel/NF-kappaB family of transcription factors in the differentiation process of dendritic cells (DC) and macrophages (MAC) was recently suggested by a number of mouse knockout studies but only little information is available for defined populations of human cells. To investigate the role of i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.2083

    authors： Ammon C,Mondal K,Andreesen R,Krause SW

    更新日期：2000-02-05 00:00:00

  • 23Na NMR detects protection by glycine and alanine against hypoxic injury in the isolated perfused rat kidney.

    abstract：:Protection against hypoxic injury by supraphysiological glycine and alanine concentrations was investigated in the isolated perfused rat kidney (IPRK). 23Na NMR detects consistent increases in total renal Na in IPRK during hypoxic perfusion. Increasing the concentration of glycine and alanine to 5 mM each produced a 3...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2121

    authors： Endre ZH,Cowin GJ,Stewart-Richardson P,Cross M,Willgoss DA,Duggleby RG

    更新日期：1994-08-15 00:00:00

  • Modified sympathetic regulation in N-type calcium channel null-mouse.

    abstract：:To elucidate the physiological importance of neuronal (N)-type calcium channels in sympathetic controls, we analyzed N-type channel-deficient (NKO) mice. Immunoprecipitation analysis revealed increased interaction between beta3 (a major accessory subunit of N-type channels) and R-type channel-forming CaV2.3 in NKO mic...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.01.087

    authors： Murakami M,Ohba T,Wu TW,Fujisawa S,Suzuki T,Takahashi Y,Takahashi E,Watanabe H,Miyoshi I,Ono K,Sasano H,Ito H,Iijima T

    更新日期：2007-03-23 00:00:00

  • Fluorescence polarization study of lipids and membranes prepared from brain hemispheres of a hibernating mammal.

    abstract：:The physical behavior of total lipids, microsomes and microsomal lipids prepared from brain hemispheres of European Hamsters (Cricetus cricetus) was approached by the measure of the fluorescence polarization of the probe 1,6-diphenyl 1,3,5-hexatriene. We compare in this study the results obtained for two critical peri...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(84)91665-6

    authors： Montaudon D,Robert J,Canguilhem B

    更新日期：1984-02-29 00:00:00

  • Palmitate and inflammatory state additively induce the expression of PTP1B in muscle cells.

    abstract：:The factors responsible for up-regulation of PTP1B, a negative regulator of insulin signaling, in insulin resistance state are not well understood. We performed a series of experiments in C2C12 muscle cells to determine the role of palmitate and an inflammatory state in regulation of PTP1B. Palmitate (0.75mM) induced ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.04.118

    authors： Parvaneh L,Meshkani R,Bakhtiyari S,Mohammadtaghvaie N,Gorganifiruzjaee S,Taheripak G,Golestani A,Foruzandeh M,Larijani B,Taghikhani M

    更新日期：2010-05-28 00:00:00

  • Efficient production and purification of functional bacteriorhodopsin with a wheat-germ cell-free system and a combination of Fos-choline and CHAPS detergents.

    abstract：:Cell-free translation is one potential approach to the production of functional transmembrane proteins. We have now examined various detergents as supplements to a wheat-germ cell-free system in order to optimize the production and subsequent purification of a functional model transmembrane protein, bacteriorhodopsin....

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2010.08.119

    authors： Genji T,Nozawa A,Tozawa Y

    更新日期：2010-10-01 00:00:00

  • Adaptation to phosphate depletion in opossum kidney cells.

    abstract：:Dietary phosphate restriction produces an adaptive increase in renal tubular Na/Pi cotransport. A similar adaptation occurs during phosphate depletion in opossum kidney cells, a continuous line of cultured renal epithelial cells. We investigated the cellular changes associated with adaptation to phosphate depletion in...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.2602

    authors： Saxena S,Dansby L,Allon M

    更新日期：1995-11-02 00:00:00

  • Prediction of pi-turns in proteins using PSI-BLAST profiles and secondary structure information.

    abstract：:Due to the structural and functional importance of tight turns, some methods have been proposed to predict gamma-turns, beta-turns, and alpha-turns in proteins. In the past, studies of pi-turns were made, but not a single prediction approach has been developed so far. It will be useful to develop a method for identify...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.06.066

    authors： Wang Y,Xue ZD,Shi XH,Xu J

    更新日期：2006-09-01 00:00:00

  • Angiotensin II induces focal adhesion kinase/paxillin phosphorylation and cell migration in human umbilical vein endothelial cells.

    abstract：:In the present study, we demonstrated that Ang II provokes a transitory enhancement of focal adhesion kinase (FAK) and paxillin phosphorylation in human umbilical endothelial cells (HUVEC). Moreover, Ang II induces a time- and dose-dependent augmentation in cell migration, but does not affect HUVEC proliferation. The ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.12.110

    authors： Montiel M,de la Blanca EP,Jiménez E

    更新日期：2005-02-25 00:00:00

  • FBXW5 reduction alleviates spinal cord injury (SCI) by blocking microglia activity: A mechanism involving p38 and JNK.

    abstract：:Traumatic spinal cord injury (SCI) is a major cause of death and lifelong disability in the world. However, the pathological process of SCI has not been fully understood. F-box/WD repeat-containing protein 5 (FBXW5), a subunit of the SCF-type E3 ubiquitin ligase complex, plays an essential role in regulating various p...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.04.086

    authors： Zhao P,Chao W,Li W

    更新日期：2019-06-25 00:00:00

  • The agglutination protein AggA from Shewanella oneidensis MR-1 is a TolC-like protein and forms active channels in vitro.

    abstract：:Type I secretion systems (TISS) are associated with the virulence of Gram-negative bacteria and the secretion of pathogenic molecular determinants. The Shewanella oneidensis MR-1 outer-membrane protein AggA is part of a TISS. Recombinant AggA expressed in Escherichia coli as inclusion bodies can be efficiently refolde...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.06.044

    authors： Theunissen S,Vergauwen B,De Smet L,Van Beeumen J,Van Gelder P,Savvides SN

    更新日期：2009-08-21 00:00:00

  • High sensitivity of tubifex for ultraviolet-B.

    abstract：:Phytoplankton and zooplankton serve as major food material for primary and secondary consumers in the marine food web. Although phytoplankton are primary targets to UV radiation damaging effects, we have demonstrated that stratospheric ozone depletion will affect zooplankton to contribute to inhibition in biomass prod...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.6055

    authors： Soni AK,Joshi PC

    更新日期：1997-02-24 00:00:00

  • Activation mechanism of solubilized epidermal growth factor receptor tyrosine kinase.

    abstract：:Dimerization of epidermal growth factor receptor (EGFR) leads to the activation of its tyrosine kinase. To elucidate whether dimerization is responsible for activation of the intracellular tyrosine kinase domain or just plays a role in the stabilization of the active form, the activated status of wild-type EGFR moiety...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.6285

    authors： Ge G,Wu J,Wang Y,Lin Q

    更新日期：2002-01-25 00:00:00

  • Structural analysis of a putative SAM-dependent methyltransferase, YtqB, from Bacillus subtilis.

    abstract：:S-adenosyl-L-methionine (SAM)-dependent methyltransferases (MTases) methylate diverse biological molecules using a SAM cofactor. The ytqB gene of Bacillus subtilis encodes a putative MTase and its biological function has never been characterized. To reveal the structural features and the cofactor binding mode of YtqB,...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.03.026

    authors： Park SC,Song WS,Yoon SI

    更新日期：2014-04-18 00:00:00

  • Upstream stimulatory factors regulate the C/EBP alpha gene during differentiation of 3T3-L1 preadipocytes.

    abstract：:During adipocyte differentiation, CCAAT/enhancer-binding protein alpha (C/EBPalpha) functions as a pleiotropic transcriptional activator of numerous adipocyte genes. The promoter of the C/EBPalpha gene has an E-box upstream of C/EBP binding site. Deletion or mutation of the E-box decreases promoter activity, suggestin...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.01.008

    authors： Kim JW,Monila H,Pandey A,Lane MD

    更新日期：2007-03-09 00:00:00