Mechanisms of exercise-induced ST-segment depression in patients without typical angina pectoris.

abstract：OBJECTIVES:Red blood cell distribution width (RDW), a measure of variation in erythrocyte volume, has been associated with several cardiovascular disorders, but the relationship with atrial fibrillation (AF) remains unclear. We investigated the association between RDW and incidence of first hospitalization due to AF in...

journal_title：Journal of internal medicine

authors： Adamsson Eryd S,Borné Y,Melander O,Persson M,Smith JG,Hedblad B,Engström G

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The bb genotype of the BsmI polymorphism of the vitamin D receptor (VDR) is more common in primary hyperparathyroidism (HPT) than in the general population in Swedish and German women. However, little is known about the association of HPT with the start codon polymorphism of the VDR (defined by FokI). OBJ...

journal_title：Journal of internal medicine

authors： Sosa M,Torres A,Martín N,Salido E,Limiñana JM,Barrios Y,De Miguel E,Betancor P

更新日期：2000-01-01 00:00:00

abstract：:The fruitless search for the cause of Crohn's disease has been conducted for more than a century. Various theories, including autoimmunity, mycobacterial infection and aberrant response to food and other ingested materials, have been abandoned for lack of robust proof. This review will provide the evidence, obtained f...

journal_title：Journal of internal medicine

authors： Segal AW

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:To assess the coexistence of hypertension and diabetes, associations with cardiovascular risk factors and the achievement of current treatment goals. DESIGN:A community-based, cross-sectional, observational study. SETTING:Hypertension and diabetes outpatient clinics in primary health care, Skara, Sweden. ...

journal_title：Journal of internal medicine

authors： Bøg-Hansen E,Lindblad U,Bengtsson K,Ranstam J,Melander A,Råstam L

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Evidence of an association between job strain and obesity is inconsistent, mostly limited to small-scale studies, and does not distinguish between categories of underweight or obesity subclasses. OBJECTIVES:To examine the association between job strain and body mass index (BMI) in a large adult population. ...

journal_title：Journal of internal medicine

authors： Nyberg ST,Heikkilä K,Fransson EI,Alfredsson L,De Bacquer D,Bjorner JB,Bonenfant S,Borritz M,Burr H,Casini A,Clays E,Dragano N,Erbel R,Geuskens GA,Goldberg M,Hooftman WE,Houtman IL,Jöckel KH,Kittel F,Knutsson A,Kos

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To describe the epidemiology, pathogenesis and clinical features of hepatocellular carcinoma (HCC) in patients with acute intermittent porphyria (AIP). DESIGN:A retrospective population-based mortality study. SUBJECTS:All inhabitants who died between 1978-1990 (2122) including 33 with AIP, in two municipali...

journal_title：Journal of internal medicine

authors： Andersson C,Bjersing L,Lithner F

更新日期：1996-10-01 00:00:00

abstract：:During the long history of development of haemoglobin (Hb)-based O2 carriers (HBOCs), many side effects of Hb molecules have become apparent. They imply the physiological importance of the cellular structure of red blood cells. Hb-vesicles (HbV) are artificial O2 carriers that encapsulate concentrated Hb solution with...

journal_title：Journal of internal medicine

authors： Sakai H,Sou K,Horinouchi H,Kobayashi K,Tsuchida E

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Although numerous multicentre studies have estimated the association between ozone exposure and mortality, there are currently no nationally representative multicentre studies of the ozone-mortality relationship in China. OBJECTIVE:To investigate the effect on total (nonaccidental) and cause-specific mortal...

journal_title：Journal of internal medicine

authors： Sun Q,Wang W,Chen C,Ban J,Xu D,Zhu P,He MZ,Li T

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To test the relationship between physical activity and physical fitness, and the relationship between these variables and the primordial risk factor blood pressure (BP). DESIGN:A cross-sectional study of all Danish pupils in the same grade at 'gymnasium' (the Danish upper secondary school). SETTING:Tests an...

journal_title：Journal of internal medicine

authors： Andersen LB

更新日期：1994-09-01 00:00:00

abstract：INTRODUCTION:Biomarkers have emerged as interesting predictors of risk in non-ST elevation acute coronary syndromes (non-ST ACS). The aim of this study was to define the utility of the combined measurement of troponin T (TnT), C-reactive protein (CRP), NT pro-brain natriuretic peptide (NT pro-BNP) and D-dimer as biomar...

journal_title：Journal of internal medicine

authors： Tello-Montoliu A,Marín F,Roldán V,Mainar L,López MT,Sogorb F,Vicente V,Lip GY

更新日期：2007-12-01 00:00:00

abstract：:Fifty consecutive patients with confirmed PCP received a high dose of cotrimoxazole for 14 d, or until development of intolerance, directly followed by reduced dose maintenance therapy. Seven individuals died during the high dose course. Twenty (47%) of the 43 survivors showed toxicity reactions that necessitated dose...

journal_title：Journal of internal medicine

authors： Eeftinck Schattenkerk JK,Lange JM,van Steenwijk RP,Danner SA

更新日期：1990-05-01 00:00:00

abstract：:A 59-year-old male patient presented with invalidating osteomalacia of 2.5 years' duration. The osteomalacia was caused by severe malabsorption due to gluten-sensitive enteropathy (GSE). There were no other signs or symptoms of GSE in this patient. Clinical presentation with monosymptomatic osteomalacia is very unusua...

journal_title：Journal of internal medicine

authors： De Boer WA,Tytgat GN

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVES:Combinations of inhaled corticosteroids (ICSs) and long-acting β2 -agonists (LABAs) are recommended for patients with moderate and severe chronic obstructive pulmonary disease (COPD). However, it is not known whether different fixed combinations are equally effective. The aim of this study was to investigate...

journal_title：Journal of internal medicine

authors： Larsson K,Janson C,Lisspers K,Jørgensen L,Stratelis G,Telg G,Ställberg B,Johansson G

更新日期：2013-06-01 00:00:00

abstract：:Serum creatine kinase (CK) is an important adjunct in the diagnosis of myocardial infarction or in monitoring for the side-effects of drugs. We report elevation of CK in patients with untreated heterozygous familial hypercholesterolaemia (FH) with no evidence of myocardial infarction. Of a group of 30 patients, 60% ha...

journal_title：Journal of internal medicine

authors： Bhatnagar D,Durrington PN,Neary R,Miller JP

更新日期：1990-11-01 00:00:00

abstract：:The introduction of biologic therapies heralded a new era in the treatment for chronic inflammatory autoimmune diseases of which rheumatoid arthritis is one of the most prevalent. From a scientific point of view, these therapies demonstrated that the targeting of individual cytokines or cell-surface markers is a very ...

journal_title：Journal of internal medicine

authors： Chatzidionysiou K,van Vollenhoven RF

更新日期：2011-06-01 00:00:00

abstract：:MicroRNAs (miRNAs) are one of a growing class of noncoding RNAs that are involved in the regulation of a wide range of metabolic processes including cellular differentiation, cell proliferation and apoptosis. The generation of miRNA is regulated in complex ways, for example by small interfering RNAs (small nucleolar a...

journal_title：Journal of internal medicine

authors： Nolte-'t Hoen EN,Van Rooij E,Bushell M,Zhang CY,Dashwood RH,James WP,Harris C,Baltimore D

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:The major aim of this study was to compare various aspects of carbohydrate, insulin, and lipoprotein metabolism, serum uric acid concentration, and blood pressure in normal subjects stratified on the basis of both plasma insulin concentration and degree of obesity. The hypothesis to be tested was that hyperin...

journal_title：Journal of internal medicine

authors： Zavaroni I,Bonini L,Fantuzzi M,Dall'Aglio E,Passeri M,Reaven GM

更新日期：1994-01-01 00:00:00

abstract：:Since 2006, the advent of increasingly larger genome-wide association studies and their meta-analyses have led to numerous, replicated findings of genetic polymorphisms associated with many diseases and traits. Early studies suggested that the identified loci generally accounted for a small fraction of the genetic var...

journal_title：Journal of internal medicine

authors： Kaprio J

更新日期：2012-11-01 00:00:00

abstract：:Although a variety of factors, inherited or environmental, can influence expression of ion channel proteins to impact on repolarization, that environment can affect genetic determinants of repolarization for intervals of varying duration is a concept that is not as generally appreciated as it should be. In the followi...

journal_title：Journal of internal medicine

authors： Rosen MR,Cohen IS

更新日期：2006-01-01 00:00:00

abstract：:Chronic nonvalvular atrial fibrillation is associated with an overall risk of thromboembolic complications of 4.5% per year. Advancing age, prior stroke or transient cerebral ischaemia, diabetes, hypertension, and impaired function of the left ventricle are known risk factors. Placebo-controlled trials have demonstrat...

journal_title：Journal of internal medicine

authors： Koefoed BG,Petersen P

更新日期：1999-04-01 00:00:00

abstract：:This review focuses on the determinants of longevity in the industrialized world, with emphasis on results from recently established data bases. Strong evidence is now available that demonstrates that in developed countries the maximum lifespan as well as the mean lifespan have increased substantially over the past ce...

journal_title：Journal of internal medicine

authors： Christensen K,Vaupel JW

更新日期：1996-12-01 00:00:00

abstract：:Cardiac troponin assays have become more sensitive over the years leading to the clinical introduction of high-sensitivity cardiac troponin assays in 2010. Their use has revolutionized the assessment of patients with chest pain in the emergency department by allowing earlier rule-in and rule-out of myocardial infarcti...

journal_title：Journal of internal medicine

authors： Holzmann MJ

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The mechanisms explaining morphological electrocardiogram (ECG) changes and increased troponin T (TnT) in acute stroke are unclear. The aims of the present study were to assess the prevalence of ECG and TnT changes in acute ischaemic stroke, to investigate whether ischaemic-like ECG changes correlate to a ri...

journal_title：Journal of internal medicine

authors： Fure B,Bruun Wyller T,Thommessen B

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the concentrations of magnesium (Mg), potassium (K) and sodium,potassium pumps (Na,K pumps) in skeletal muscle in patients with chronic obstructive lung disease (COLD) treated with or without diuretics. DESIGN:An open cross-sectional study. SETTING:COLD patients admitted to the Medical Departme...

journal_title：Journal of internal medicine

authors： Ravn HB,Dørup I

更新日期：1997-01-01 00:00:00

abstract：:Previous studies in patients with peripheral arterial disease (PAD) have shown that the prognosis is relatively good when the distal systolic ankle index (ankle systolic pressure/arm systolic pressure) is above 50% and the distal toe systolic pressure is above 40 mmHg. In 132 patients suspected of PAD in the legs we i...

journal_title：Journal of internal medicine

authors： Christensen JH,Freundlich M,Jacobsen BA,Falstie-Jensen N

更新日期：1989-08-01 00:00:00

abstract：:The effects of resuscitation on patients who died suddenly out of hospital were evaluated after the introduction of early defibrillation performed by ambulance personnel using semi-automatic defibrillators. Resuscitation attempts were initiated in 548 patients during the 1-year study period. Mean ambulance delay was 7...

journal_title：Journal of internal medicine

authors： Jakobsson J,Rehnqvist N,Nyquist O

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:The original definition of microalbuminuria (20-200 microg min-1 or 15-150 microg min-1 overnight) is based on studies of patients with diabetes, in whom microalbuminuria was associated with increased risk of chronic renal failure. In a recent report an overnight urinary albumin excretion (UAE) above only 5 ...

journal_title：Journal of internal medicine

authors： Klausen KP,Scharling H,Jensen JS

更新日期：2006-09-01 00:00:00

abstract：:Sepsis is a major clinical problem in intensive care. The mortality in septic shock is high, and predominantly due to cardiovascular collapse and multiple organ dysfunction. In sepsis high levels of circulating hyaluronan have been found, correlating to disease severity and prognosis. The reason behind the increased l...

journal_title：Journal of internal medicine

authors： Berg S

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Chronic Chlamydia pneumoniae infection is considered as a cardiovascular risk factor and antibodies are commonly analysed by the subjective microimmunofluorescence (MIF) test. We wanted to investigate the C. pneumoniae IgA- and IgG seroprevalence in young survivors of myocardial infarction and matched contro...

journal_title：Journal of internal medicine

authors： Halvorsen DS,Børvik T,Njølstad I,Gutteberg TJ,Vorland LH,Hansen JB

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:To investigate the concordance of anti-hepatitis C virus (anti-HCV) reactivity by a second-generation enzyme immunoassay (EIA-2) and by a four-antigen recombinant immunoblot assay (4-RIBA) in homosexual men, in comparison with that found in other sexually active groups and blood donors. DESIGN:Prospective s...

journal_title：Journal of internal medicine

authors： Andreu J,Abad MA,Sanchez-Quijano A,Torronteras R,Luque F,Garcia de las Heras J,Soto B,Pineda JA,Leal M,Lissen E

更新日期：1994-07-01 00:00:00