A patient with osteomalacia as single presenting symptom of gluten-sensitive enteropathy.

abstract：OBJECTIVE:To ascertain whether carotid intraplaque haemorrhage (IH) in patients undergoing carotid artery surgery is a predictor of increased cardiac mortality over a 5.5 year follow-up. DESIGN AND SUBJECTS:Carotid artery plaques were obtained at surgery from 47 consecutive patients (41 men, six women), median age 67 ...

journal_title：Journal of internal medicine

authors： Falke P,Mätzsch T,Sternby NH,Bergqvist D,Stavenow L

更新日期：1995-08-01 00:00:00

abstract：:The link between inflammation and metabolism was apparent already early last century, but has recently been revitalized following molecular studies of atherosclerosis, obesity and insulin resistance. A growing list of nuclear receptors, pivotal players in lipid, xenobiotic and energy metabolism has been identified as ...

journal_title：Journal of internal medicine

authors： Arulampalam V

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:To examine to what extent traditional biomedical risk factors and social factors can predict, separately or jointly, first-ever stroke event, and to explore to what extent other risk factors might add to hypertension/elevated blood pressure as a stroke risk factor. DESIGN:An incident case-referent study. S...

journal_title：Journal of internal medicine

authors： Ohgren B,Weinehall L,Stegmayr B,Boman K,Hallmans G,Wall S

更新日期：2000-12-01 00:00:00

abstract：:Twenty-six consecutive patients with primary biliary cirrhosis (PBC) from northern Sweden were studied regarding the occurrence and features of Sjögren's syndrome (SS). In more than 50% of the patients the rose bengal dye test showed conjunctival and/or corneal staining. In six patients keratoconjunctivitis sicca (KCS...

journal_title：Journal of internal medicine

authors： Uddenfeldt P,Danielsson A,Forssell A,Holm M,Ostberg Y

更新日期：1991-11-01 00:00:00

abstract：:Calcium is important for bone health. It has been customary to focus on dietary calcium intake, but of central importance for the body needs in the individual patient is the actual calcium absorption. This absorption consists of an active vitamin D-mediated component and a passive diffusional component. A number of di...

journal_title：Journal of internal medicine

authors： Charles P

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVES:To investigate if an insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene associates with HLA-DR alleles previously found to be of prognostic interest in Scandinavian sarcoidosis patients. This may contribute to characteristics associated with these HLA-DR alleles, such as a ...

journal_title：Journal of internal medicine

authors： Planck A,Eklund A,Yamaguchi E,Grunewald J

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the prognostic value of exercise testing performed soon after acute myocardial infarction (AMI) in patients treated with thrombolytic therapy. DESIGN:A 1-year prospective follow-up of 185 subjects treated with thrombolytic therapy who survived AMI, and who performed exercise testing 3 weeks afte...

journal_title：Journal of internal medicine

authors： Abboud L,Hir J,Eisen I,Markiewicz W

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVES:The objective was to analyse whether a favourable change in risk factors, caused by a comprehensive risk factor modification programme, affected intima-media thickness (IMT) in the common carotid artery, and whether any such change was associated with a change in cardiovascular events during a 6-year follow-...

journal_title：Journal of internal medicine

authors： Agewall S,Fagerberg B,Berglund G,Schmidt C,Wendelhag I,Wikstrand J,Risk Factor Intervention Study Group, Sweden.

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to define the phenotype in three families with mild haemophilia A and to determine restriction fragment length polymorphisms (RFLP), which could support a hypothesis of a common progenitor of the families. DESIGN:Family survey. SETTING:Index cases were identified in and outside hos...

journal_title：Journal of internal medicine

authors： Jensson O,Stenbjerg Bernvil S,Jónsdóttir S,Ingerslev J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Splenectomy is accompanied by a life-long risk of overwhelming postsplenectomy infection (OPSI), mainly caused by polysaccharide (PS) encapsulated bacteria such as Streptococcus pneumoniae. Despite extensive prophylactic efforts the mortality and morbidity rates remain high. The present study was based on a ...

journal_title：Journal of internal medicine

authors： Landgren O,Björkholm M,Konradsen HB,Söderqvist M,Nilsson B,Gustavsson A,Axdorph U,Kalin M,Grimfors G

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVES:The serum levels of the catabolic cytokine TNF-alpha are often raised in malnourished chronic heart failure patients as well as in chronic renal failure (CRF) patients. Angiotensin-converting enzyme (ACE) inhibitors are often used in these patients and may decrease TNF-alpha and IL-1beta levels in vitro and ...

journal_title：Journal of internal medicine

authors： Stenvinkel P,Andersson P,Wang T,Lindholm B,Bergström J,Palmblad J,Heimbürger O,Cederholm T

更新日期：1999-11-01 00:00:00

abstract：:Sepsis is a major clinical problem in intensive care. The mortality in septic shock is high, and predominantly due to cardiovascular collapse and multiple organ dysfunction. In sepsis high levels of circulating hyaluronan have been found, correlating to disease severity and prognosis. The reason behind the increased l...

journal_title：Journal of internal medicine

authors： Berg S

更新日期：1997-07-01 00:00:00

abstract：:A patient with undiagnosed, long-standing coeliac disease had multiple hot spots on skeletal scintigraphy, similar to those observed in malignant disease metastatic to the skeleton. A gluten-free diet corrected the pathological laboratory values, and a repeat skeletal scintigram 15 months after the first one was norma...

journal_title：Journal of internal medicine

authors： Paul R

更新日期：1990-10-01 00:00:00

abstract：:Personalized medicine involves the selection of the safest and most effective pharmacological treatment based on the molecular characteristics of the patient. In the case of anticancer drugs, tumour cell alterations can have a great impact on drug activity and, in fact, most biomarkers predicting response originate fr...

journal_title：Journal of internal medicine

authors： Rodríguez-Antona C,Taron M

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To explore the relation between 25-hydroxyvitamin D deficiency and frailty. Frailty is a multidimensional phenotype that describes declining physical function and a vulnerability to adverse outcomes in the setting of physical stress such as illness or hospitalization. Low serum concentrations of 25-hydroxyvit...

journal_title：Journal of internal medicine

authors： Wilhelm-Leen ER,Hall YN,Deboer IH,Chertow GM

更新日期：2010-08-01 00:00:00

abstract：:Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because of recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use of new imaging technologies, advances in large-scale 'om...

journal_title：Journal of internal medicine

authors： Bergström G,Berglund G,Blomberg A,Brandberg J,Engström G,Engvall J,Eriksson M,de Faire U,Flinck A,Hansson MG,Hedblad B,Hjelmgren O,Janson C,Jernberg T,Johnsson Å,Johansson L,Lind L,Löfdahl CG,Melander O,Östgren CJ,

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To study the short-term efficacy, tolerability and safety of the treatment with gemfibrozil 600 mg twice daily or placebo in male patients with established atherosclerosis, with a lipid profile matching the 'high triglyceride-low high-density lipoprotein (HDL) cholesterol trait'. DESIGN:Double-blind randomiz...

journal_title：Journal of internal medicine

authors： Knipscheer HC,Nurmohamed MT,Van den Ende A,Plaat B,Pruijs HJ,Mulder WJ,Kastelein JJ

更新日期：1994-10-01 00:00:00

abstract：CONTEXT:The classical end-point to terminate the 72-h fast in a patient evaluated for a hypoglycaemic disorder is the occurrence of hypoglycaemic symptoms in association with a low plasma glucose level. However, neither the symptoms nor the plasma glucose level have been exactly defined. OBJECTIVE:To determine whether...

journal_title：Journal of internal medicine

authors： Wiesli P,Brändle M,Schwegler B,Lehmann R,Spinas GA,Schmid C

更新日期：2002-12-01 00:00:00

abstract：:A 61-year-old female patient, treated for hyperthyroidism with thiamazole, developed a severe maturation arrest in the granulocytic lineage and a total agranulocytosis. Subcutaneous GM-CSF was started immediately and given for 6 days. Bone marrow samples were taken before GM-CSF therapy and on days 3 and 8. An increas...

journal_title：Journal of internal medicine

authors： Björkholm M,Pisa P,Arver S,Beran M

更新日期：1992-11-01 00:00:00

abstract：:A 38-year-old Japanese woman was hospitalized for susceptibility to respiratory tract infections. Clinical examinations revealed asymptomatic primary cholestasis, abnormally elevated immunoglobulin M (IgM) and antimitochondrial antibody, being consistent with asymptomatic primary biliary cirrhosis. Three years later h...

journal_title：Journal of internal medicine

authors： Take H,Kubota K,Tamura K,Kurabayashi H,Tamura J,Shirakura T

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVES:To examine the occurrence over time of the metabolic syndrome (MetS) according to different definitions and the relation to change during follow-up in carotid artery intima-media thickness (IMT), measured by ultrasound. DESIGN:A cohort of 316, originally 58-year-old men, initially free of diabetes and cardi...

journal_title：Journal of internal medicine

authors： Wallenfeldt K,Hulthe J,Fagerberg B

更新日期：2005-07-01 00:00:00

abstract：:Although biofilms have been observed early in the history of microbial research, their impact has only recently been fully recognized. Biofilm infections, which contribute to up to 80% of human microbial infections, are associated with common human disorders, such as diabetes mellitus and poor dental hygiene, but also...

journal_title：Journal of internal medicine

authors： Bjarnsholt T,Buhlin K,Dufrêne YF,Gomelsky M,Moroni A,Ramstedt M,Rumbaugh KP,Schulte T,Sun L,Åkerlund B,Römling U

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:To assess the coexistence of hypertension and diabetes, associations with cardiovascular risk factors and the achievement of current treatment goals. DESIGN:A community-based, cross-sectional, observational study. SETTING:Hypertension and diabetes outpatient clinics in primary health care, Skara, Sweden. ...

journal_title：Journal of internal medicine

authors： Bøg-Hansen E,Lindblad U,Bengtsson K,Ranstam J,Melander A,Råstam L

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:There is growing evidence that endogenous hypertriglyceridaemia is frequently accompanied by a state of insulin resistance. The present study was performed to determine whether patients with primary endogenous hypertriglyceridaemia commonly have abnormalities in plasma concentrations and turnover rates of fre...

journal_title：Journal of internal medicine

authors： Mostaza JM,Vega GL,Snell P,Grundy SM

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:To examine whether interleukin-1 receptor antagonist (IL-1Ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (MetS) and whether its predictive power is independent of C-reactive protein (CRP), an established marker of inflammation. We further examined whether genetic vari...

journal_title：Journal of internal medicine

authors： Luotola K,Pietilä A,Zeller T,Moilanen L,Kähönen M,Nieminen MS,Kesäniemi YA,Blankenberg S,Jula A,Perola M,Salomaa V,Health 2000 and FINRISK97 Studies.

更新日期：2011-03-01 00:00:00

abstract：:The field of nanotechnology has been a significant research focus in the last thirty years. This emphasis is due to the unique optical, electrical, magnetic, chemical and biological properties of materials approximately ten thousand times smaller than the diameter of a hair strand. Researchers have developed methods t...

journal_title：Journal of internal medicine

authors： Sindhwani S,Chan WCW

更新日期：2021-01-22 00:00:00

abstract：:Primary hyperparathyroidism (HPT) has been associated with hypertension, hyperinsulinaemia, hypertriglyceridaemia and hyperuricaemia. In the present study, plasma ionized calcium (Ca2+) was studied in relation to cardiovascular risk factors in 20 subjects with mild hypertension. Plasma Ca2+ was found to be negatively ...

journal_title：Journal of internal medicine

authors： Lind L,Wengle B,Lithell H,Ljunghall S

更新日期：1992-04-01 00:00:00

abstract：:To determine the folic acid absorption characteristics of patients with human immunodeficiency virus (HIV) infection, a prospective, controlled, result-blind single-dose oral absorption study was conducted. A total of 25 subjects were fasted and given 5 mg oral folic acid; blood samples were taken at time zero and aft...

journal_title：Journal of internal medicine

authors： Revell P,O'Doherty MJ,Tang A,Savidge GF

更新日期：1991-09-01 00:00:00

abstract：:Poikilothermia syndrome is a rare cause of intrinsic thermoregulatory failure. Patients with this syndrome regulate body temperature poorly, if at all. Recently, a patient was referred to us who had clinical evidence of poikilothermia syndrome, as well as long-standing multiple sclerosis. Computerized tomography and m...

journal_title：Journal of internal medicine

authors： Kurz A,Sessler DI,Tayefeh F,Goldberger R

更新日期：1998-11-01 00:00:00

abstract：:Serum creatine kinase (CK) is an important adjunct in the diagnosis of myocardial infarction or in monitoring for the side-effects of drugs. We report elevation of CK in patients with untreated heterozygous familial hypercholesterolaemia (FH) with no evidence of myocardial infarction. Of a group of 30 patients, 60% ha...

journal_title：Journal of internal medicine

authors： Bhatnagar D,Durrington PN,Neary R,Miller JP

更新日期：1990-11-01 00:00:00