One year's experience of early defibrillation in Stockholm.

abstract：OBJECTIVE:To study the impact of the cost of pharmaceuticals on physicians' decisions about drug prescription. DESIGN:A simulation protocol for the treatment of two patients, one with mild and the other with a severe form of urinary tract infection (UTI), was designed. Thirty family physicians in outpatient clinics an...

journal_title：Journal of internal medicine

authors： Hart J,Salman H,Bergman M,Neuman V,Rudniki C,Gilenberg D,Matalon A,Djaldetti M

更新日期：1997-05-01 00:00:00

abstract：:We determined whether ketoconazole prophylaxis might reduce Candida colonization and infections in adult patients with acute leukaemia. During first-remission induction therapy 50 patients were treated with 200 mg ketoconazole administered orally daily, while 57 patients received placebo in a double-blind, randomized ...

journal_title：Journal of internal medicine

authors： Palmblad J,Lönnqvist B,Carlsson B,Grimfors G,Järnmark M,Lerner R,Ljungman P,Nyström-Rosander C,Petrini B,Oberg G

更新日期：1992-04-01 00:00:00

abstract：:Pneumonia exhibits a broad range of severity, from mildly symptomatic at one end to fulminant septic shock and death at the other. Although an adequate inflammatory response is necessary for the clearance of microorganisms, excessive inflammation can lead to ongoing local and systemic damage. Because of this extended ...

journal_title：Journal of internal medicine

authors： Meijvis SC,van de Garde EM,Rijkers GT,Bos WJ

更新日期：2012-07-01 00:00:00

abstract：:The value of thorough examination of the case history as a diagnostic tool on hospitalization of patients with suspected myocardial infarction was investigated in three independent prospective studies. Use of a limited number of pain-related elements (= 'criteria'), that had already been obtained in the emergency room...

journal_title：Journal of internal medicine

authors： Jonsbu J,Rollag A,Aase O,Lippestad CT,Arnesen KE,Erikssen J,Koss A

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVE:To investigate the demographic, clinical, biochemical and genotypic features of patients with erythropoietic protoporphyria (EPP) in a Swedish cohort. DESIGN:Cross-sectional questionnaire, biochemical and genetic study. SETTING:Sweden. SUBJECTS:Fifty-one Swedish individuals known in 2008 to have EPP confir...

journal_title：Journal of internal medicine

authors： Wahlin S,Floderus Y,Stål P,Harper P

更新日期：2011-03-01 00:00:00

abstract：:Alpha-1 antitrypsin (AAT) deficiency is an under-recognized hereditary disorder associated with the premature onset of chronic obstructive pulmonary disease, liver cirrhosis in children and adults, and less frequently, relapsing panniculitis, systemic vasculitis and other inflammatory, autoimmune and neoplastic diseas...

journal_title：Journal of internal medicine

authors： de Serres F,Blanco I

更新日期：2014-10-01 00:00:00

abstract：:The past few years have witnessed a major breakthrough in the understanding of the molecular mechanisms and ultrastructural changes behind the development of proteinuria. The discovery of several proteins in the glomerular podocyte and slit diaphragm, where mutations lead to disease, has revealed the importance of thi...

journal_title：Journal of internal medicine

authors： Tryggvason K,Pettersson E

更新日期：2003-09-01 00:00:00

abstract：:Recent studies have demonstrated that replacement of C-peptide to normal physiological concentrations in insulin-dependent diabetic (IDDM) patients on a short-term basis (1-3 h) results in decreased glomerular hyperfiltration, augmented glucose utilization and improved autonomic nervous function. More prolonged admini...

journal_title：Journal of internal medicine

authors： Wahren J,Johansson BL,Wallberg-Henriksson H,Linde B,Fernqvist-Forbes E,Zierath JR

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVES:To evaluate the predictive accuracy of the scoring system Rapid Acute Physiology score (RAPS) in nonsurgical patients attending the emergency department (ED) regarding in-hospital mortality and length of stay in hospital (LOS), and to investigate whether the predictive ability of RAPS could be improved by ex...

journal_title：Journal of internal medicine

authors： Olsson T,Terent A,Lind L

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:To assess the clinical course of renal function in relation to risk factors in NIDDM patients with normo- and microalbuminuria. DESIGN:Prospective clinical study. SETTING:Outpatient diabetic clinic. SUBJECTS:Thirty-two NIDDM patients with normo- or microalbuminuria followed for (mean (range)) 5.5 (3.3-7.5...

journal_title：Journal of internal medicine

authors： Nielsen S,Schmitz A,Rehling M,Mogensen CE

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:To examine the occurrence over time of the metabolic syndrome (MetS) according to different definitions and the relation to change during follow-up in carotid artery intima-media thickness (IMT), measured by ultrasound. DESIGN:A cohort of 316, originally 58-year-old men, initially free of diabetes and cardi...

journal_title：Journal of internal medicine

authors： Wallenfeldt K,Hulthe J,Fagerberg B

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Periodontal disease is associated with cardiovascular disease (CVD) but it is unknown if periodontal disease severity is associated with asymptomatic carotid plaque. The aim of the current population-based, observational study was to investigate if signs of periodontal disease are associated with the occurre...

journal_title：Journal of internal medicine

authors： Jönsson D,Orho-Melander M,Demmer RT,Engström G,Melander O,Klinge B,Nilsson PM

更新日期：2020-03-01 00:00:00

abstract：:Hypertriglyceridaemia, as defined by fasting triglyceride levels of greater than 2.8 mmol l-1, is a prevalent dyslipoproteinaemia in our population. The underlying pathophysiological mechanisms that result in elevations of plasma triglycerides are heterogeneous and, in most cases, incompletely understood. However, in ...

journal_title：Journal of internal medicine

authors： Fojo SS,Brewer HB

更新日期：1992-06-01 00:00:00

abstract：:Cancer is a genetic disease caused by 'gain of function' mutations of oncogenes and 'loss of function' mutations of tumour suppressors and of genes involved in DNA repair mechanisms. The RET gene encodes a tyrosine kinase receptor for molecules belonging to the glial cell line-derived neurotrophic factor (GDNF) family...

journal_title：Journal of internal medicine

authors： Santoro M,Melillo RM,Carlomagno F,Visconti R,De Vita G,Salvatore G,Lupoli G,Fusco A,Vecchio G

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:Combinations of inhaled corticosteroids (ICSs) and long-acting β2 -agonists (LABAs) are recommended for patients with moderate and severe chronic obstructive pulmonary disease (COPD). However, it is not known whether different fixed combinations are equally effective. The aim of this study was to investigate...

journal_title：Journal of internal medicine

authors： Larsson K,Janson C,Lisspers K,Jørgensen L,Stratelis G,Telg G,Ställberg B,Johansson G

更新日期：2013-06-01 00:00:00

abstract：:The objective was to review the current status of meta-analysis, the process of combining the results of similar investigations, which was described in 1976. It has evolved rapidly, and thousands have already been published. Meta-analysis may be performed in a narrative form or in the preferred statistical format, whi...

journal_title：Journal of internal medicine

authors： Conn HO

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:IgA nephropathy (IgAN) is a common complex disease with a strong genetic involvement. We aimed to identify novel, rare, highly penetrant risk variants combining family-based linkage analysis with whole-exome sequencing (WES). METHODS:Linkage analysis of 16 kindreds of South Italian ancestry was performed us...

journal_title：Journal of internal medicine

authors： Cox SN,Pesce F,El-Sayed Moustafa JS,Sallustio F,Serino G,Kkoufou C,Giampetruzzi A,Ancona N,Falchi M,Schena FP,European IgAN Consortium.

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:We estimated the prevalence, incidence and risk factors of left ventricular hypertrophy (LVH) in a prospective cohort study of 26 489 participants. MATERIAL AND METHODS:The LVH was defined as Minnesota Code 310 on electrocardiogram (ECG). Everyone with this code at first visit was defined as a prevalence cas...

journal_title：Journal of internal medicine

authors： Thrainsdottir IS,Hardarson T,Thorgeirsson G,Sigvaldason H,Sigfusson N

更新日期：2003-04-01 00:00:00

abstract：:Primary hyperparathyroidism (HPT) has been associated with hypertension, hyperinsulinaemia, hypertriglyceridaemia and hyperuricaemia. In the present study, plasma ionized calcium (Ca2+) was studied in relation to cardiovascular risk factors in 20 subjects with mild hypertension. Plasma Ca2+ was found to be negatively ...

journal_title：Journal of internal medicine

authors： Lind L,Wengle B,Lithell H,Ljunghall S

更新日期：1992-04-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder that affects approximately 10% of the population. Diet triggers symptoms in the vast majority of individuals with IBS. In view of this, there has been a focus on the role of diet in IBS. The diets currently being headlined for IBS include ...

journal_title：Journal of internal medicine

authors： Rej A,Aziz I,Tornblom H,Sanders DS,Simrén M

更新日期：2019-11-01 00:00:00

abstract：:A female patient developed warfarin resistance after 2 years of satisfactory therapy. Only a third of orally administered warfarin was absorbed, the clearance of warfarin was normal. The patient was also resistant for dicoumarol, while phenandione had satisfactory effect on the prothrombin time (PT). ...

journal_title：Journal of internal medicine

authors： Talstad I,Gamst ON

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVES:To investigate if an insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene associates with HLA-DR alleles previously found to be of prognostic interest in Scandinavian sarcoidosis patients. This may contribute to characteristics associated with these HLA-DR alleles, such as a ...

journal_title：Journal of internal medicine

authors： Planck A,Eklund A,Yamaguchi E,Grunewald J

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to quantify the inter-relationship between bone mineral density and physical activity, muscle strength, and body mass composition in a group of healthy 16-20-year-old women. DESIGN:A cross-sectional study. SETTING:Reykjavik area. SUBJECTS:Two-hundred and fifty-four Icelandic Caucas...

journal_title：Journal of internal medicine

authors： Valdimarsson O,Kristinsson JO,Stefansson SO,Valdimarsson S,Sigurdsson G

更新日期：1999-05-01 00:00:00

abstract：:We describe a 48-year-old woman with recurrent severe hypoglycaemia apparently caused by a paraprotein with insulin-binding capacity. Very high fasting values were found for serum insulin (170 and > 250 mU l-1) as well as for proinsulin 125 pmol l-1 and an insulinoma was suspected. Hypoglycaemia developed after an ora...

journal_title：Journal of internal medicine

authors： Arnqvist HJ,Halban PA,Mathiesen UL,Zahnd G,von Schenck H

更新日期：1993-10-01 00:00:00

abstract：:Left ventricular filling pattern was assessed by pulsed Doppler echocardiography at rest and during handgrip exercise in 33 healthy middle-aged subjects. The peak mitral flow-velocities during the early rapid filling phase (E) and during late (atrial) filling (A) were measured and the ratio of these peak flow-velociti...

journal_title：Journal of internal medicine

authors： Airaksinen KE,Ikäheimo MJ,Huikuri HV,Koistinen MJ,Linnaluoto M,Takkunen JT

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that normoalbuminuric type 1 diabetic patients segregate into groups with normal and elevated ambulatory blood pressure. To evaluate diurnal variation of blood pressure assessed by individual or fixed night-time periods. DESIGN:Cross-sectional study. SETTING:Tertiary referral centre. ...

journal_title：Journal of internal medicine

authors： Hansen KW,Pedersen MM,Christiansen JS,Mogensen CE

更新日期：1993-08-01 00:00:00

abstract：:Six patients with acute renal failure, in five cases due to acute crescentic glomerulonephritis and in one case due to total bilateral renal cortical necrosis, were studied. All had serum erythropoietin (EPO) concentrations in the normal range, despite a relatively severe anaemia. Half-life and plasma clearance of int...

journal_title：Journal of internal medicine

authors： Thaysen JH,Nielsen OJ,Brandi L,Szpirt W

更新日期：1991-04-01 00:00:00

abstract：:We identified two cases of chronic active hepatitis with liver fibrosis induced by lipid lowering drugs of the statin and fibrate classes despite regular monitoring of transaminases. There are few reports of clinically significant hepatitis induced by these drugs and even fewer cases of fibrosis. Given the growing use...

journal_title：Journal of internal medicine

authors： Punthakee Z,Scully LJ,Guindi MM,Ooi TC

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:The clinical features of 80 patients with primary Sjögren's syndrome (PSS) were revised in order to evaluate the descriptive and analytical facilities of a newly proposed model for classification of the exocrine and nonexocrine disease manifestations in PSS. DESIGN:Retrospective, long-term (median 7.5 years...

journal_title：Journal of internal medicine

authors： Asmussen K,Andersen V,Bendixen G,Schiødt M,Oxholm P

更新日期：1996-06-01 00:00:00

abstract：:Increasing evidence suggests that paraneoplastic syndromes may be mediated by tumour-related cytokine release, although the specific factor(s) involved remain poorly defined. Colony-stimulating factors (CSF) and interleukins (IL) promote colony growth in semi-solid media and, when administered in recombinant form, inc...

journal_title：Journal of internal medicine

authors： Wetzler M,Estrov Z,Talpaz M,Markowitz A,Gutterman JU,Kurzrock R

更新日期：1993-10-01 00:00:00