Blood pressure, physical fitness and physical activity in 17-year-old Danish adolescents.

abstract：OBJECTIVES:There is currently widespread exposure to the toxic metal cadmium through the diet as well as through smoking, and it has been suggested that cadmium exposure may increase the risk of cardiovascular disease. Here we examined whether cadmium exposure is associated with prevalence and growth of atherosclerotic...

journal_title：Journal of internal medicine

authors： Fagerberg B,Bergström G,Borén J,Barregard L

更新日期：2012-12-01 00:00:00

abstract：:The International RET Mutation Consortium was first convened as part of the Fifth International Workshop on Multiple Endocrine Neoplasia, Stockholm, Sweden, in an attempt to analyse the relationship of RET mutation and disease phenotype in the autosomal dominantly inherited multiple endocrine neoplasia type 2 (MEN 2) ...

journal_title：Journal of internal medicine

authors： Mulligan LM,Marsh DJ,Robinson BG,Schuffenecker I,Zedenius J,Lips CJ,Gagel RF,Takai SI,Noll WW,Fink M

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVES:Physical activity (PA) is a preventive strategy for cardiovascular disease and for managing cardiovascular risk factors. There is little information on the effectiveness of PA for the prevention of cardiovascular outcomes once cardiovascular disease is present. Thus, we studied the relationship between PA at...

journal_title：Journal of internal medicine

authors： Fossum E,Gleim GW,Kjeldsen SE,Kizer JR,Julius S,Devereux RB,Brady WE,Hille DA,Lyle PA,Dahlöf B

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Evidence of an association between job strain and obesity is inconsistent, mostly limited to small-scale studies, and does not distinguish between categories of underweight or obesity subclasses. OBJECTIVES:To examine the association between job strain and body mass index (BMI) in a large adult population. ...

journal_title：Journal of internal medicine

authors： Nyberg ST,Heikkilä K,Fransson EI,Alfredsson L,De Bacquer D,Bjorner JB,Bonenfant S,Borritz M,Burr H,Casini A,Clays E,Dragano N,Erbel R,Geuskens GA,Goldberg M,Hooftman WE,Houtman IL,Jöckel KH,Kittel F,Knutsson A,Kos

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The UKPDS 34 showed that intensive treatment with metformin significantly reduces macrovascular end-points and mortality in individuals with newly diagnosed type 2 diabetes compared with intensive treatment with insulin or sulphonylurea derivatives, despite similar glycaemic control. How this should be expla...

journal_title：Journal of internal medicine

authors： Wulffelé MG,Kooy A,de Zeeuw D,Stehouwer CD,Gansevoort RT

更新日期：2004-07-01 00:00:00

abstract：:Here, the notion of distributive justice is explored in relation to the introduction and the application of new medical technologies within the clinical setting. The point of departure is that, in the decision making process on what is necessary and fair in patient care, participants will mobilize different ethical mo...

journal_title：Journal of internal medicine

authors： van der Kloot Meijburg HH

更新日期：1995-12-01 00:00:00

abstract：:In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates the number of erythrocytes within the circulation to provide adequate tissue oxygenation. EPO also mediates other effects directed towards optimizing oxygen delivery to tissues, e.g. modulating regional blood flow and reducing b...

journal_title：Journal of internal medicine

authors： Brines M,Cerami A

更新日期：2008-11-01 00:00:00

abstract：:A major challenge in the growing field of bioelectronic medicine is the development of tissue interface technologies promoting device integration with biological tissues. Materials based on organic bioelectronics show great promise due to a unique combination of electronic and ionic conductivity properties. In this re...

journal_title：Journal of internal medicine

authors： Löffler S,Melican K,Nilsson KPR,Richter-Dahlfors A

更新日期：2017-07-01 00:00:00

abstract：:Calcium is important for bone health. It has been customary to focus on dietary calcium intake, but of central importance for the body needs in the individual patient is the actual calcium absorption. This absorption consists of an active vitamin D-mediated component and a passive diffusional component. A number of di...

journal_title：Journal of internal medicine

authors： Charles P

更新日期：1992-02-01 00:00:00

abstract：:We observed two patients with hypercholesterolaemia and tendon xanthomas associated with apolipoprotein (apoE-7) E-7, a rare variant of the apoE isoforms. Both suffered from coronary artery disease and had undergone a coronary bypass operation. Their cholesterol levels were 268 and 310 mg dl-1, respectively. Both pati...

journal_title：Journal of internal medicine

authors： Ueyama Y,Nozaki S,Yanagi K,Hiraoka H,Nakagawa T,Sakai N,Jiao S,Yamashita S,Matsuzawa Y

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:To investigate the relationship between cardiac repolarization (QT interval duration) and intima media thickness (IMT) of the carotid arteries as surrogate measures of subclinical atherosclerosis. DESIGN:Prospective study with consecutive subjects enrolled in the SAPHIR program (Salzburg Atherosclerosis Pre...

journal_title：Journal of internal medicine

authors： Strohmer B,Pichler M,Iglseder B,Paulweber B

更新日期：2005-03-01 00:00:00

abstract：:Recent observed changes in Earth's climate, to which humans have contributed substantially, are affecting various health outcomes. These include altered distributions of some infectious disease vectors (ticks at high latitudes, malaria mosquitoes at high altitudes), and an uptrend in extreme weather events and associa...

journal_title：Journal of internal medicine

authors： McMichael AJ,Lindgren E

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to define the phenotype in three families with mild haemophilia A and to determine restriction fragment length polymorphisms (RFLP), which could support a hypothesis of a common progenitor of the families. DESIGN:Family survey. SETTING:Index cases were identified in and outside hos...

journal_title：Journal of internal medicine

authors： Jensson O,Stenbjerg Bernvil S,Jónsdóttir S,Ingerslev J

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:To clarify the mechanisms by which smoking is associated to toxic and nontoxic goitre and thyroid nodules. DESIGN:Cohort study. SETTING:Sweden. SUBJECTS:A cohort of 874,507 parous women identified through the Medical Birth Registry, with smoking behaviour assessed through self-reported information at the ...

journal_title：Journal of internal medicine

authors： Galanti MR,Granath F,Cnattingius S,Ekbom-Schnell A,Ekbom A

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:To study fasting and postmethionine-loading (increment and decrement) plasma homocysteine levels in end-stage renal disease (ESRD) patients in relation to B-vitamin status and after folic acid treatment without or with betaine. DESIGN:Plasma total homocysteine (tHcy) and methionine levels were measured in c...

journal_title：Journal of internal medicine

authors： van Guldener C,Janssen MJ,de Meer K,Donker AJ,Stehouwer CD

更新日期：1999-02-01 00:00:00

abstract：:Ebola virus disease (EVD) is a zoonotic disease that causes severe haemorrhagic fever, with high fatality rates of up to 90% in humans. Today, there is no effective treatment available. Person-to-person transmission occurs through exposure to blood or body fluids, which can threaten other household members and first-l...

journal_title：Journal of internal medicine

authors： Mirazimi A

更新日期：2015-09-01 00:00:00

abstract：:Gene mutations at the low density lipoprotein (LDL) receptor locus were screened in 210 alleles of Japanese patients with familial hypercholesterolaemia (FH). In the present study, two types of novel mutation were identified by genomic Southern blotting using human LDL receptor cDNA probes. An approximately 12 kb dele...

journal_title：Journal of internal medicine

authors： Kajinami K,Mabuchi H,Inazu A,Fujita H,Koizumi J,Takeda R,Matsue T,Kibata M

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To assess the prophylactic efficacy of aspirin and a high-dose antioxidant vitamin combination in patients with peripheral arterial disease (PAD) in terms of reduction of the risk of a first vascular event (myocardial infarction, stroke, vascular death) and critical limb ischaemia. DESIGN:Randomized, placebo...

journal_title：Journal of internal medicine

authors： Critical Leg Ischaemia Prevention Study (CLIPS) Group.,Catalano M,Born G,Peto R

更新日期：2007-03-01 00:00:00

abstract：:We describe a 57-year-old male with hypertrophic obstructive cardiomyopathy and occult blood loss. Septal alcohol ablation reduced the left ventricular outflow tract obstruction and eliminated recurrent bleeding. The case resembles Heyde's syndrome, i.e. the association between occult gastrointestinal bleeding and aor...

journal_title：Journal of internal medicine

authors： Riis Hansen P,Hassager C

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To analyse the associations between serum gamma-glutamyl transpeptidase activity (GTP) and the components of the metabolic syndrome. DESIGN:Cross-sectional, observational study of hypertensive patients and controls. SETTING:The participating subjects visited the research laboratory of the Department of Inte...

journal_title：Journal of internal medicine

authors： Rantala AO,Lilja M,Kauma H,Savolainen MJ,Reunanen A,Kesäniemi YA

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:To evaluate beneficial effects of postmenopausal hormone replacement therapy (HRT) on endothelial function, measured as intraplatelet cyclic guanosine monophosphate (cGMP, mediator of nitric oxide), cyclic adenosine monophosphate (cAMP, mediator of prostacyclin) and plasma endothelin-1 (ET-1), and on monocyt...

journal_title：Journal of internal medicine

authors： Anwaar I,Rendell M,Gottsäter A,Lindgärde F,Hulthén UL,Mattiasson I

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:To determine the possibility of very early prognostic stratification based on electrocardiograms (ECGs) at rest and/or cardiac enzyme levels after an episode of suspected unstable coronary heart disease. DESIGN AND SETTING:Men with suspected unstable angina or non-Q-wave myocardial infarction were studied i...

journal_title：Journal of internal medicine

authors： Nyman I,Areskog M,Areskog NH,Swahn E,Wallentin L

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) is the leading infectious cause of death in developed countries. Risk stratification has previously been difficult. METHODS:Markers of cardiac stress (B-type natriuretic peptide, BNP) and inflammation (C-reactive protein, white blood cell count, procalcitonin) as well as t...

journal_title：Journal of internal medicine

authors： Christ-Crain M,Breidthardt T,Stolz D,Zobrist K,Bingisser R,Miedinger D,Leuppi J,Tamm M,Mueller B,Mueller C

更新日期：2008-08-01 00:00:00

abstract：:Chances are that you have come across membrane proteins many times in your professional life: ion channels, aquaporins, G-protein-coupled receptors, drug resistance proteins. But it is also quite likely that you have never bothered to think about what the implications are of being a membrane protein, as opposed to a s...

journal_title：Journal of internal medicine

authors： von Heijne G

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:To evaluate (i) the demineralizing effect of L-thyroxine (LT4) therapy at doses mildly inhibiting serum thyroid stimulating hormone (TSH) in patients with benign nodular goitre; (ii) the efficacy of treatment on nodule size. DESIGN:Cross-sectional study comparing euthyroid women with nodular goitre treated ...

journal_title：Journal of internal medicine

authors： Baldini M,Gallazzi M,Orsatti A,Fossati S,Leonardi P,Cantalamessa L

更新日期：2002-05-01 00:00:00

abstract：:Current orthodoxy states that coronary heart disease results from the unhealthy lifestyles of westernized adults together with a contribution from genetic inheritance. This does not provide a secure basis for prevention of the disease. Geographical studies gave the first clue that the disease originates during intra-u...

journal_title：Journal of internal medicine

authors： Barker DJ

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Cigarette smoking has been identified as a major modifiable risk factor for coronary heart disease and mortality. However, findings on the relationship between smoking and atrial fibrillation (AF) have been inconsistent. Furthermore, findings from previous studies were based on self-reported smoking. OBJECT...

journal_title：Journal of internal medicine

authors： Zuo H,Nygård O,Vollset SE,Ueland PM,Ulvik A,Midttun Ø,Meyer K,Igland J,Sulo G,Tell GS

更新日期：2018-01-01 00:00:00

abstract：:Although a variety of factors, inherited or environmental, can influence expression of ion channel proteins to impact on repolarization, that environment can affect genetic determinants of repolarization for intervals of varying duration is a concept that is not as generally appreciated as it should be. In the followi...

journal_title：Journal of internal medicine

authors： Rosen MR,Cohen IS

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to estimate the prevalence of hypertrophic cardiomyopathy (HCM) in 3607 men from the Reykjavik study of 1979-81. Of these, 452 men had an abnormal (group A) and 3155 a normal electrocardiogram. An echocardiographic control group of 128 men was selected from cohorts with a normal electroca...

journal_title：Journal of internal medicine

authors： Agnarsson UT,Hardarson T,Hallgrimsson J,Sigfusson N

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:Peroxidation of lipoproteins may be of critical importance in the development of atherosclerosis. Tocopherol is considered to be the most effective lipid-soluble antioxidant. The main aim of this study was to measure the serum tocopherol concentrations in a Swedish reference population and to relate them to ...

journal_title：Journal of internal medicine

authors： Ohrvall M,Tengblad S,Vessby B

更新日期：1993-07-01 00:00:00