Primary systemic amyloidosis presenting as extensive cutaneous ulceration.

abstract：BACKGROUND:Intralesional Candida antigen has been used as immunotherapy to treat refractory warts in the immunocompetent pediatric and adult populations but has not been reported in individuals with human immunodeficiency virus (HIV). PURPOSE:To examine if Candida antigen resulted in clearance of medically refractory,...

journal_title：Journal of cutaneous medicine and surgery

authors： Wong A,Crawford RI

更新日期：2013-09-01 00:00:00

abstract：:Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semi...

journal_title：Journal of cutaneous medicine and surgery

authors： García-de-la-Fuente MR,Santacana M,Vilardell F,Pujol RM,Gari E,Casanova JM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

journal_title：Journal of cutaneous medicine and surgery

authors： Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

更新日期：2018-11-01 00:00:00

abstract：:Psoriasis is a T-cell mediated skin disease that affects approximately 2% of the population worldwide. Despite the prevalence of the disease and long-standing efforts to develop strategies to treat it, there is a need for safe and effective therapies to treat psoriasis, particularly the more severe forms. Biological a...

journal_title：Journal of cutaneous medicine and surgery

authors： Langley RG,Ho V,Lynde C,Papp KA,Poulin Y,Shear N,Toole J,Zip C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Sjögren syndrome (SS) is a chronic autoimmune inflammatory disease that involves primarily the exocrine glands, resulting in their functional impairment. SS typically presents as dry eyes (xerophthalmia) and dry mouth (xerostomia). This process can manifest either as the independent phenomenon of primary SS ...

journal_title：Journal of cutaneous medicine and surgery

authors： Kittridge A,Routhouska SB,Korman NJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:In 1997, it was reported that a PTEN gene deletion, a common genetic mutation in Cowden's disease (CD), was identified in a patient with Bannayan-Riley-Ruvacalba (BRR), suggesting that the two diseases were allelic. However, the clinical overlap between the two diseases has largely remained unclear. OBJECTI...

journal_title：Journal of cutaneous medicine and surgery

authors： Blum RR,Rahimizadeh A,Kardon N,Lebwohl M,Wei H

更新日期：2001-05-01 00:00:00

abstract：:A renaissance is taking place in the field of wound healing. Interest in wounds has probably never been so great, and a number of key therapeutic advances in the last 2 or 3 years are only an indication of more progress to come. In large part, we are benefitting from decades of basic research that has provided the kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Falanga V

更新日期：1998-12-01 00:00:00

abstract：:The duration of response to treatment with alefacept has been assessed in patients with moderate to severe chronic plaque psoriasis who responded to alefacept therapy in phase 2 and phase 3 clinical studies. In a phase 2 trial, duration of response was based on time to retreatment with alefacept. In two phase 3 studie...

journal_title：Journal of cutaneous medicine and surgery

authors： Krueger GG

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Whereas several literature reviews have discussed the role of excipients in drug-related reactions, no article has focused specifically on those found in oral dermatologic medications. METHODS:The Compendium of Pharmaceuticals and Specialties (CPS) was used to reference the inert ingredients found in oral d...

journal_title：Journal of cutaneous medicine and surgery

authors： Noiles K,Vender R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Cutaneous reactions to drugs are among the most common clinical manifestations of adverse drug events (ADEs); however, data on outpatient cutaneous adverse drug events (CADEs) are limited. PURPOSE:To provide national estimates of outpatient CADEs and determine their most frequent causes. METHODS:Outpatient...

journal_title：Journal of cutaneous medicine and surgery

authors： Koelblinger P,Dabade TS,Gustafson CJ,Davis SA,Yentzer BA,Kiracofe EA,Feldman SR

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Mast cells stimulate inflammation and itch sensation in the skin by releasing various mediators when they are activated. Stress exacerbates some skin diseases. We have reported that inhalation of certain odorants modulates immune reactions in the skin. OBJECTIVE:The possible usage of odorants in the regulat...

journal_title：Journal of cutaneous medicine and surgery

authors： Hosoi J,Tanida M,Tsuchiya T

更新日期：2003-07-01 00:00:00

abstract：:The primary goal of treatment for external genital warts (EGWs) is to eradicate visible lesions and address symptoms that may accompany them, but it does not address the underlying virus. Left untreated, warts may grow, remain the same, or spontaneously regress as a result of being cleared by the immune system. Howeve...

journal_title：Journal of cutaneous medicine and surgery

authors： Vender R,Bourcier M,Bhatia N,Lynde C

更新日期：2013-12-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Sun-induced malignancies (basal cell and squamous cell carcinomas) are common in oculocutaneous albinism, however, the incidence of malignant melanoma is a topic of controversy. OBJECTIVE:We have reviewed the literature and report a case of a woman with oculocutaneous albinism with an amelanotic melanoma of...

journal_title：Journal of cutaneous medicine and surgery

authors： Streutker CJ,McCready D,Jimbow K,From L

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration. OBJECTIVE:To review the mechanisms of action, efficacy and safety data, and practical recommendations for ingenol mebutate. METHODS:The PubMed and clinicaltrials.gov databases were searche...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Paquet M

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by massive infection with human papillomaviruses (HPVs) and development of skin cancer. Myelodysplastic syndromes (MDSs) are a group of chronic conditions that involve dysplastic hematopoiesis, peripheral blood cytopenias, and a high...

journal_title：Journal of cutaneous medicine and surgery

authors： Oliveira WR,Ferreira GN,Rady PL,Festa C,Tyring SK

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan C,Min ZS,Xue Y,Zhu WY

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:It has been postulated that periodic acid-Schiff staining of basement membrane can predict direct immunofluorescence patterns seen in epidermolysis bullosa acquisita and bullous pemphigoid. It has also been suggested that the type of inflammatory infiltrate or presence of fraying of basal keratinocytes may d...

journal_title：Journal of cutaneous medicine and surgery

authors： Gardner KM,Crawford RI

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Pustular psoriasis is an uncommon form of psoriasis that often affects areas of the hands and feet. It typically manifests as small pustules that develop within erythematous areas of the palms and soles. Infliximab, a tumor necrosis factor inhibitor, can be used to treat pustular psoriasis. Infliximab can al...

journal_title：Journal of cutaneous medicine and surgery

authors： English PL,Vender R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:We present a case of strongyloidiasis presenting as larva currens 38 years after potential exposure in a country with what is typically thought of as low epidemiologic risk. CONCLUSION:This case highlights several important features of strongyloidiasis, including its varied epidemiology, long incubation per...

journal_title：Journal of cutaneous medicine and surgery

authors： Showler A,Boggild AK

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Laser epilation is now used widely as a clinical alternative to electrolysis for the removal of unwanted hair. All of the laser systems presently being used produce a reliable temporary hair loss by inducing telogen. Most of the published studies use follow-up periods of 6 months or less after the last treat...

journal_title：Journal of cutaneous medicine and surgery

authors： Laughlin SA,Dudley DK

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Efalizumab is a recombinant humanized IgG1-kappa isotype monoclonal antibody that binds to CD11a, inhibiting T-cell activation. It has been approved for the treatment of moderate to severe plaque psoriasis. Efalizumab has been associated with the development of skin eruptions during the administration period...

journal_title：Journal of cutaneous medicine and surgery

authors： Rallis E,Verros C,Karanikola E,Valaskatzi A,Papaconstantis M

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Cutaneous T-cell lymphoma is a rare subtype of posttransplantation lymphoproliferative disease, with only 29 cases reported in the literature to date, the majority of which are post-renal transplantation. Only a few were reported after pancreas, heart, and bone marrow transplantation. There have been no repo...

journal_title：Journal of cutaneous medicine and surgery

authors： Al Ajroush N,Rafique Sheikh K,Kadry R,Almutawa A,Alfadley A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Omalizumab is a third-line treatment for chronic spontaneous urticaria (CSU). Studies investigating the use of higher doses of omalizumab in patients unresponsive to regular doses are limited. OBJECTIVES:This study aims to investigate the effectiveness and safety of omalizumab 450 mg in CSU. METHODS:A retr...

journal_title：Journal of cutaneous medicine and surgery

authors： Salman A,Comert E

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administr...

journal_title：Journal of cutaneous medicine and surgery

authors： Wilson JK,Phelps KC,Feldman SR

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. OBJECTIVE:This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. CONCLUSION:Urbach s...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Giant basal cell carcinomas (GBCC) can demonstrate very malignant behavior and pose a surgical challenge. OBJECTIVE:To present a surgical technique utilizing Mohs and the resection of narrow bands of tissue to excise a GBCC that created a large facial defect of 5 cm × 2 cm. METHODS:A unique combination of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Nolan K,Henry M,Shohet M,Elahi E,Marmur E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The self-inflicted dermatoses such as acne excorieé and neurotic excoriations are often chronic, recurring, and resistant to standard dermatologic therapies. OBJECTIVE:We present a 28-year-old woman with longstanding acne excorieé, whose acne started at age 14 years and was followed by acne excorieé at age ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta MA,Gupta AK

更新日期：2001-01-01 00:00:00