Skin manifestations of outpatient adverse drug events in the United States: a national analysis.

abstract：OBJECTIVE:To better understand cutaneous photosensitivity reactions, a review of its etiologic factors, clinical characteristics, pathogenesis, and treatment modalities was undertaken. METHODS:Articles discussing the above aspects of phototoxic and photoallergic reactions were used to demonstrate what is currently kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Lankerani L,Baron ED

更新日期：2004-11-01 00:00:00

abstract：:The duration of response to treatment with alefacept has been assessed in patients with moderate to severe chronic plaque psoriasis who responded to alefacept therapy in phase 2 and phase 3 clinical studies. In a phase 2 trial, duration of response was based on time to retreatment with alefacept. In two phase 3 studie...

journal_title：Journal of cutaneous medicine and surgery

authors： Krueger GG

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:It has been demonstrated that hypertrophic scar fibroblasts (HSFs) overexpress collagen messenger ribonucleic acid (mRNA) and protein, especially alpha1 collagen. Antisense nucleic acids are effective in inhibiting harmful or uncontrolled gene expression, suggesting that antisense ribonucleic acid (RNA) can ...

journal_title：Journal of cutaneous medicine and surgery

authors： Ju-Lin X,Shao-Hai Q,Tian-Zeng L,Chao-Quan L,Hou-Dong L,Ying-Bin X,Xu-Sheng L,Bin S,Hui-Zhen L,Yong H

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This is a somewhat rare case of a 19-year-old African American female with multiple cutaneous granular cell tumors. Granular cell tumors are of neural origin, except in rare cases, and are considered benign, with a low incidence of malignancy. The clinical presentation varies greatly, but these...

journal_title：Journal of cutaneous medicine and surgery

authors： Henry M,Perry A

更新日期：2011-11-01 00:00:00

abstract：:We report a case of an 17-year-old male with a drug reaction in the spectrum of Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), triggered by carbamazepine, who was succesfully treated with the combination of dexamethasone, cyclosporine, and etanercept. This triple therapy halted and prevented skin epi...

journal_title：Journal of cutaneous medicine and surgery

authors： Coulombe J,Belzile E,Duhamel A,Rault P,Buteau C,DeBruycker JJ,Bussières JF

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Hand dermatitis (HD) is one of the most common skin conditions; however, it is not a homogeneous disease entity. The severity of HD may range from very mild cases to severe chronic forms, which may result in prolonged disability and, occasionally, refractory HD. Chronic hand dermatitis (CHD) is associated wi...

journal_title：Journal of cutaneous medicine and surgery

authors： Lynde C,Guenther L,Diepgen TL,Sasseville D,Poulin Y,Gulliver W,Agner T,Barber K,Bissonnette R,Ho V,Shear NH,Toole J

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Apligraf is a bioengineered skin product composed of neonatal fibroblasts and keratinocytes. The FDA has approved Apligraf for the treatment of chronic venous ulcers and diabetic ulcers. OBJECTIVE:We review the development of bioengineered skin, examine the cellular activities of various growth factors that...

journal_title：Journal of cutaneous medicine and surgery

authors： Shen JT,Falanga V

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Ear keloids continue to be a therapeutic challenge. OBJECTIVE:To evaluate the clinical success of a modified "oyster splint technique." METHODS:Ten patients with an ear keloid agreed to receive the compression therapy. After surgical removal, a compressive device made of acrylic resin was applied on top of...

journal_title：Journal of cutaneous medicine and surgery

authors： Hassel JC,Löser C,Koenen W,Kreuter A,Hassel AJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE), a rare acquired elastolytic disorder, occurs in postmenopausal, elderly women and is characterized by soft, white-yellow papules that localize on the neck and supraclavicular regions and often coalesce into cobblestone plaques. It has no s...

journal_title：Journal of cutaneous medicine and surgery

authors： Valbuena V,Assaad D,Yeung J

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Laser epilation is now used widely as a clinical alternative to electrolysis for the removal of unwanted hair. All of the laser systems presently being used produce a reliable temporary hair loss by inducing telogen. Most of the published studies use follow-up periods of 6 months or less after the last treat...

journal_title：Journal of cutaneous medicine and surgery

authors： Laughlin SA,Dudley DK

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Efalizumab is a recombinant humanized IgG1-kappa isotype monoclonal antibody that binds to CD11a, inhibiting T-cell activation. It has been approved for the treatment of moderate to severe plaque psoriasis. Efalizumab has been associated with the development of skin eruptions during the administration period...

journal_title：Journal of cutaneous medicine and surgery

authors： Rallis E,Verros C,Karanikola E,Valaskatzi A,Papaconstantis M

更新日期：2009-03-01 00:00:00

abstract：:The primary goal of treatment for external genital warts (EGWs) is to eradicate visible lesions and address symptoms that may accompany them, but it does not address the underlying virus. Left untreated, warts may grow, remain the same, or spontaneously regress as a result of being cleared by the immune system. Howeve...

journal_title：Journal of cutaneous medicine and surgery

authors： Vender R,Bourcier M,Bhatia N,Lynde C

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Sjögren syndrome (SS) is a chronic autoimmune inflammatory disease that involves primarily the exocrine glands, resulting in their functional impairment. SS typically presents as dry eyes (xerophthalmia) and dry mouth (xerostomia). This process can manifest either as the independent phenomenon of primary SS ...

journal_title：Journal of cutaneous medicine and surgery

authors： Kittridge A,Routhouska SB,Korman NJ

更新日期：2011-01-01 00:00:00

abstract：:Actinic keratosis (AK), located on sun-exposed areas of the skin, is an increasing global health burden. Multiple ablative and topical treatment options are available to manage this disease; however, topical treatment options are receiving significant interest because AK is commonly associated with areas of substantia...

journal_title：Journal of cutaneous medicine and surgery

authors： Jorizzo JL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma is a rare, aggressive, malignant cutaneous tumor of the elderly or immunosuppressed individuals that usually appears on sun-exposed areas of the body. Its pathogenesis is still debated, and, currently, no standardized treatment exists. OBJECTIVE:To provide a current updated review of t...

journal_title：Journal of cutaneous medicine and surgery

authors： Zampetti A,Feliciani C,Massi G,Tulli A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The onychodystrophies associated with Sézary syndrome (SzS) have rarely been described in the literature. We performed a retrospective analysis of SzS patients at a single institution and compared our data with previous publications. OBJECTIVES:The objectives of this study were to identify and describe the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Damasco FM,Geskin LJ,Akilov OE

更新日期：2019-07-01 00:00:00

abstract：:This document is a concise, current, and practical guide for dermatologists and other health care providers managing adult patients with moderate-to-severe atopic dermatitis (AD). The recommendations made here are based on a consensus of specialists with extensive experience managing patients with AD. Topics reviewed ...

journal_title：Journal of cutaneous medicine and surgery

authors： Hong CH,Gooderham MJ,Albrecht L,Bissonnette R,Dhadwal G,Gniadecki R,Grewal P,Kirchhof MG,Landells I,Lansang P,Lynde CW,Papp KA,Poulin Y,Sussman G,Turchin I,Wiseman M,Yeung J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:All kinds of bees, wasps, and hornets are members of the hymenoptera order. Local hypersensitivity reactions after bee stings are very common and well studied. However, tissue necroses following untreated bee stings are extremely rare and they are not well documented. OBJECTIVE:Two extremely rare cases of e...

journal_title：Journal of cutaneous medicine and surgery

authors： Koçer U,Ozer Tiftikcioğlu Y,Mete Aksoy H,Karaaslan O

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Cryptococcosis is an opportunistic infection caused by the encapsulated yeast Cryptococcus neoformans. This ubiquitous organism has emerged as a frequent finding in immunosuppressed patients, especially those with underlying malignancies, organ transplants, and the acquired immune deficiency syndrome (AIDS)....

journal_title：Journal of cutaneous medicine and surgery

authors： Ingleton R,Koestenblatt E,Don P,Levy H,Szaniawski W,Weinberg JM

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Biologics have transformed the management of moderate to severe psoriasis. The persistency of biologics lacks real-world data. OBJECTIVES:To quantify drug survival of infliximab (IFX), adalimumab (ADA), etanercept (ETA), and ustekinumab (UST) and to identify potential factors affecting drug survival. METHO...

journal_title：Journal of cutaneous medicine and surgery

authors： Verma L,Mayba JN,Gooderham MJ,Verma A,Papp KA

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Pyodermatitis-pyostomatitis vegetans (PDPSV) is a rare inflammatory disorder of the skin and oral mucosa that is commonly associated with inflammatory bowel disease (IBD). Ocular involvement is uncommon. OBJECTIVE:Given the association with IBD, it is important for dermatologists to be aware of the varying ...

journal_title：Journal of cutaneous medicine and surgery

authors： Dupuis EC,Haber RM,Robertson LH

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

journal_title：Journal of cutaneous medicine and surgery

authors： Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

更新日期：2018-11-01 00:00:00

abstract：:We describe a family with supernumerary nipples and kidney and urinary tract malformations. The proband is a 59-year-old man with a supernumerary nipple and recently identified hypoplastic kidney, bladder diverticulum, and hypotonic bladder. His mother also has a supernumerary nipple and a recently identified hypoplas...

journal_title：Journal of cutaneous medicine and surgery

authors： Brown J,Schwartz RA

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Fewer dermatologists than other clinical specialists are entering and being retained as physicians in the Canadian medical workforce. Studies suggest that dermatologist numbers may influence skin disease outcomes. No study has questioned whether the number of clinical dermatologists can influence academic pr...

journal_title：Journal of cutaneous medicine and surgery

authors： Canzi Lanzini R,Fallen RS,Wismer J,Lima HC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:A patient with concurrent Raynaud disease presented for hyperhidrosis of the axillae and palms. After a positive response to botulinum toxin type A (BoNTA) for axillary hyperhidrosis, she returned requesting palmar treatment. OBJECTIVES:Our goal was to investigate the effect of BoNTA on Raynaud disease in c...

journal_title：Journal of cutaneous medicine and surgery

authors： Kossintseva I,Barankin B

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administr...

journal_title：Journal of cutaneous medicine and surgery

authors： Wilson JK,Phelps KC,Feldman SR

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Forty-nine years ago the first complete and authoritative English text on the physiology and biochemistry of the skin was published by Stephen Rothman, an early basic researcher in dermatology. OBJECTIVE:The purpose of the article is to learn more about Stephen Rothman and his 1954 text, to learn more about...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：2004-09-01 00:00:00