Abstract:
:Gastric adenocarcinoma is the most common malignancy of the upper gastrointestinal tract. During the past two decades it has migrated toward the gastroesophageal junction. Gastroesophageal reflux and obesity may play a role. Recent research suggests that a number of biologic and molecular differences exist in patients with gastric cancer. Further investigation in these areas may help in predicting outcome and directing therapy. Gastric cancer is not a curable condition when metastases are present. However, postoperative chemotherapy plus chemoradiotherapy, in the Intergroup trial 0116, prolonged the overall and disease-free survival rates of patients after a curative (R0) resection. It should be considered the new standard of care in patients with gastric cancer who have undergone curative resection with stage Ib-IV disease. Preoperative therapy strategies may increase the likelihood of R0 resection and remain an area of active investigation. Finally, development of more active agents is needed for the treatment of metastatic tumors.
journal_name
Curr Opin Gastroenteroljournal_title
Current opinion in gastroenterologyauthors
Yao JC,Ajani JAdoi
10.1097/00001574-200011000-00009subject
Has Abstractpub_date
2000-11-01 00:00:00pages
516-21issue
6eissn
0267-1379issn
1531-7056pii
00001574-200011000-00009journal_volume
16pub_type
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3283422482
更新日期:2011-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200001000-00003
更新日期:2000-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200207000-00009
更新日期:2002-07-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200411000-00007
更新日期:2004-11-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200311000-00003
更新日期:2003-11-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200409000-00008
更新日期:2004-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/MOG.0b013e3282f2b0fb
更新日期:2008-01-01 00:00:00
abstract::Advances in cellular and molecular biology of extrahepatic cholangiocarcinoma and gallbladder adenocarcinoma are providing innovative means for the diagnosis and treatment of biliary tract cancer. Similarly, refinements in noninvasive studies--including helical computed tomography, magnetic resonance cholangiopancreat...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200109000-00009
更新日期:2001-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200001000-00013
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2005-01-01 00:00:00
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更新日期:2015-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3283460c7d
更新日期:2011-05-01 00:00:00