Iron deficiency anemia: diagnosis and management.

abstract：PURPOSE OF REVIEW:Jaundice, the physical finding associated with hyperbilirubinemia, results when the liver is unable to properly metabolize or excrete bilirubin. The purpose of this review is to examine some of the most common causes of jaundice in adults, provide insight into the diagnostic evaluation of jaundice, an...

journal_title：Current opinion in gastroenterology

authors： Sullivan JI,Rockey DC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent progress on endoscopic diagnosis and treatment of esophageal high-grade intraepithelial neoplasia and early adenocarcinoma and critically analyzes the literature in the context of preexisting scientific data. RECENT FINDINGS:Narrow band imaging and computed virtual chrom...

journal_title：Current opinion in gastroenterology

authors： Seewald S,Ang TL,Groth S,Zhong Y,Bertschinger P,Altorfer J,Thonke F,Soehendra N

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The introduction of novel molecular imaging modalities that can not only define disease states on the basis of structural changes and morphology, but also allow in-vivo visualization and characterization of molecular and biochemical alterations on a cellular level add a new dimension to our current di...

journal_title：Current opinion in gastroenterology

authors： Atreya R,Neurath MF

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To present the clinical, endoscopic, and histologic features of eosinophilic esophagitis (EoE), review the current diagnostic guidelines for EoE, and present an approach for diagnosis of EoE. It will also highlight selected techniques that are under development that may be useful in the future for dia...

journal_title：Current opinion in gastroenterology

authors： Dellon ES

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To outline the recommended course of action when a subepithelial lesion is encountered during upper endoscopy. It will focus on the endoscopic and endosonographic features common to gastrointestinal stromal tumors, and the optimal tests performed to confirm the diagnosis of a gastrointestinal stromal ...

journal_title：Current opinion in gastroenterology

authors： Rodriguez SA,Faigel DO

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Enteral nutrition is now the preferred route of nutritional support in malnourished and ICU patients. Studies providing evidence of its efficacy, techniques of administration, and outcome are appearing daily in the literature. This review presents the most important publications in this area and criti...

journal_title：Current opinion in gastroenterology

authors： Jeejeebhoy KN

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapy for inflammatory bowel diseases (IBD) has changed dramatically in recent years with a wider use of immunomodulators and the introduction of antitumor necrosis factor (anti-TNF) agents. This article reviews the existing data on the long-term efficacy of biologics, that is, anti-TNF agents, for ...

journal_title：Current opinion in gastroenterology

authors： Sokol H,Seksik P,Cosnes J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the advances in diagnostic modalities and management options for defecatory dysfunction and highlight the areas in need of further research. RECENT FINDINGS:The diagnostic utility of high-resolution anorectal manometry (ARM), which has emerged as a promising tool for the diagnosis of def...

journal_title：Current opinion in gastroenterology

authors： Neshatian L

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Prevention of colorectal cancer relies on the detection and removal of colorectal neoplasia. Recent advances in mucosal imaging and inspection techniques have increased the detection of small and diminutive colorectal polyps with unknown clinical impact. The ability to accurately predict whether a pol...

journal_title：Current opinion in gastroenterology

authors： Coe SG,Wallace MB

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review evidence relating to the strength of associations that have appeared in largely observational studies, between high-dose or long-term use of proton pump inhibitor drugs and certain possibly attributable side-effects, which emerge from studies confounded by other variables. In retrospective s...

journal_title：Current opinion in gastroenterology

authors： McCarthy DM

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Noroviruses (NoVs) are the most common cause of epidemic and sporadic cases of acute gastroenteritis worldwide. This review summarizes recent NoV disease burden estimates, epidemiology findings and provides an update on virus-like particle (VLP) vaccine studies. RECENT FINDINGS:NoVs are the leading c...

journal_title：Current opinion in gastroenterology

authors： Ramani S,Atmar RL,Estes MK

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Alcohol consumption is increasing globally, as are complications of alcohol-related liver disease, including the most severe manifestation, alcoholic hepatitis. Despite the increased prevalence, many patients hospitalized with alcoholic hepatitis are either not diagnosed or inadequately treated leadin...

journal_title：Current opinion in gastroenterology

authors： Aday AW,Mitchell MC,Casey LC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing antimicrobial resistance in Salmonella Typhi is a serious public health concern, especially in industrializing countries. Here we review recent clinical and laboratory data concerning the evolution of antimicrobial resistance, with particular reference to the emergence resistance against fl...

journal_title：Current opinion in gastroenterology

authors： Karkey A,Thwaites GE,Baker S

更新日期：2018-01-01 00:00:00

abstract：:A part of living in a new and exciting era for the biologic sciences and medicine, novel high throughput tools allow exploration of the human genome in an unprecedented manner. This "information revolution" is fueled by the study of genome-wide expression profiles for complex biologic and pathophysiologic conditions u...

journal_title：Current opinion in gastroenterology

authors： Fernandez-Zapico ME,Callahan G,Delgado S,Urrutia R

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing use of small bowel endoscopy unravels ulcers in a relevant number of patients. Although often attributed to inflammatory bowel disease (IBD), these ulcers may be unspecific or caused by a variety of other diseases. This review summarizes the recent literature related to differential diagnos...

journal_title：Current opinion in gastroenterology

authors： Keuchel M,Kurniawan N,Baltes P

更新日期：2019-05-01 00:00:00

abstract：:Over the past several years, the pharmacologic treatment of obesity has undergone changes in safety, efficacy, and therapeutic targeting. The prevalence of cardiac valvulopathy associated with treatment with phentermine, fenfluramine, and dexfenfluramine is now becoming clarified with the publication of longer-term st...

journal_title：Current opinion in gastroenterology

authors： Kushner RF,Manzano H

更新日期：2002-03-01 00:00:00

abstract：:The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...

journal_title：Current opinion in gastroenterology

authors： Logsdon CD

更新日期：2000-09-01 00:00:00

abstract：:The development of small bowel transplantation has long been hindered by the immunological and infectious barriers peculiar to the small bowel. Gradual progress has been achieved during the past decade with the use of tacrolimus and the availability of better anti-infection prophylaxis. The current status of small bow...

journal_title：Current opinion in gastroenterology

authors： Prasad KR,Pollard SG

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Even though recent accumulated data can help to understand fundamental molecular mechanisms of progression of cholangiocarcinoma (CCA), its incidence and mortality still keep increasing worldwide with poor prognosis. As appropriate animal disease models are critical to fill the gap between the finding...

journal_title：Current opinion in gastroenterology

authors： Ko KS,Peng J,Yang H

更新日期：2013-05-01 00:00:00

abstract：:In the past year, numerous important papers were published on chronic pancreatitis, its causes, and its diagnosis; the cause of fibrosis; and pain in pancreatic cancer. More than 750 mutations have been described in the cystic fibrosis transmembrane regulator (CFTR) gene. Some mutations cause relatively mild reduction...

journal_title：Current opinion in gastroenterology

authors： Chari ST,Dimagno EP

更新日期：1999-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The human gut is the natural habitat for a large and dynamic bacterial community. There is a substantial body of evidence implicating the resident flora in the pathogenesis of chronic intestinal inflammation. This review discusses the possible role of a microbial imbalance in the pathophysiology of in...

journal_title：Current opinion in gastroenterology

authors： Guarner F

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review new advances in gastric interventional endoscopy. RECENT FINDINGS:Implementation of gastric endoscopy as a therapeutic option in obesity, gastric cancer, and gastroparesis. SUMMARY:Less invasive new gastric endoscopic procedures can potentially replace currently offered laparoscopic approa...

journal_title：Current opinion in gastroenterology

authors： Mahmoud M,Holzwanger E,Wassef W

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF THIS REVIEW:In the last 2 years, several studies have been published that will change the management of patients with Barrett's esophagus. In this review, we will discuss the most relevant studies as well as future prospects in this field. RECENT FINDINGS:Long-term follow-up studies have shown that to be co...

journal_title：Current opinion in gastroenterology

authors： Bergman JJ

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...

journal_title：Current opinion in gastroenterology

authors： Takakura WR,Tabibian JH,Bowlus CL

更新日期：2017-03-01 00:00:00

abstract：:Intensive investigation into the interactions of Helicobacter pylori with the human host during the period of this review has led to several important developments in our understanding of H. pylori pathogenesis. There is direct evidence to support a central role for bacterial adhesion to host gastric epithelial Lewis ...

journal_title：Current opinion in gastroenterology

authors： Wilson KT,Fantry GT

更新日期：1999-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a need for novel therapies for inflammatory bowel diseases (IBDs) that are well tolerated and effective. Currently, mesenchymal stem/stromal cells (MSCs) are being investigated in clinical trials for treatment of IBD. In this review, we update the recently published studies with an emphasis o...

journal_title：Current opinion in gastroenterology

authors： Dave M,Jaiswal P,Cominelli F

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Barrett's esophagus is the premalignant condition for esophageal cancer and the diagnosis of esophageal adenocarcinoma on index endoscopy is increasing. Many advanced endoscopic techniques are available and aim to identify Barrett's esophagus-associated neoplasia earlier, thereby preventing progressio...

journal_title：Current opinion in gastroenterology

authors： Sutton RA,Sharma P

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Intestinal fibrosis is a potentially serious complication of inflammatory bowel disease and its pathophysiology is still unclear. This review will discuss recent developments relating to sources of fibroblasts in intestinal inflammation, mediators that modulate fibroblast activation and function, as w...

journal_title：Current opinion in gastroenterology

authors： Rieder F,Fiocchi C

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to provide an overview of the role of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in inflammatory bowel disease (IBD). RECENT FINDINGS:Human genetic studies have identified several UPR-related genes and autophagy-related genes as IBD risk loc...

journal_title：Current opinion in gastroenterology

authors： Hosomi S,Kaser A,Blumberg RS

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In both Crohn's disease and ulcerative colitis, the tissue damage results from an inappropriate or exaggerated immune response to antigens of the gut microflora. This review summarizes current knowledge regarding the role of immune-inflammatory mediators in the pathogenesis of inflammatory bowel disea...

journal_title：Current opinion in gastroenterology

authors： Monteleone G,Fina D,Caruso R,Pallone F

更新日期：2006-07-01 00:00:00