Abstract:
PURPOSE OF REVIEW:To review new advances in gastric interventional endoscopy. RECENT FINDINGS:Implementation of gastric endoscopy as a therapeutic option in obesity, gastric cancer, and gastroparesis. SUMMARY:Less invasive new gastric endoscopic procedures can potentially replace currently offered laparoscopic approaches in many fields. In this article, we will review the use of endoscopic sleeve gastroplasty as a weight loss procedure, endoscopic submucosal dissection in treatment of early gastric cancer, and gastric per-oral endoscopic myotomy in treatment of refractory gastroparesis. These procedures can increase access to bariatric weigh loss procedures, provide an organ-saving curative option for early gastric cancer, and offer a new modality to improve refractory gastroparesis.
journal_name
Curr Opin Gastroenteroljournal_title
Current opinion in gastroenterologyauthors
Mahmoud M,Holzwanger E,Wassef Wdoi
10.1097/MOG.0000000000000397subject
Has Abstractpub_date
2017-11-01 00:00:00pages
461-466issue
6eissn
0267-1379issn
1531-7056journal_volume
33pub_type
杂志文章,评审abstract::This article provides an overview of advances in understanding the cellular and molecular mechanisms and regulation of intestinal absorption processes of vitamins. The vitamins covered are the water-soluble vitamins folic acid, cobalamin (vitamin B12), biotin, pantothenic acid, and thiamine (vitamin B1) and the lipid-...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-199903000-00015
更新日期:1999-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The dynamic interplay of the intestinal microbiota and host has been the focus of many studies because of its impact on the health status in human life. Recent reports on the time-resolved immune and metabolic interactions between the host and microbiota, as well as the molecular signatures that mark ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e328365d365
更新日期:2013-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Rotavirus infection is the leading cause of severe dehydrating gastroenteritis, responsible for an estimated 440,000 deaths per year in children less than 5 years of age worldwide. There was great optimism when the first rotavirus vaccine was licensed in the United States in July 1998 (rhesus rotaviru...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Significant advances in the pathophysiology, diagnosis and management of the complications of portal hypertension that have occurred in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to experimental studies aimed at modifying the factors that lead to port...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000218962.93806.9a
更新日期:2006-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000333
更新日期:2017-03-01 00:00:00
abstract::The neurohormonal control of pancreatic exocrine secretion is a complex interaction of multiple pathways involving a large number of gut hormones, neurotransmitters, and neuropeptides. Recent studies have elucidated a role for cholecystokinin in the regulation of bicarbonate and fluid secretion from pancreatic duct ce...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200209000-00003
更新日期:2002-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Irritable bowel syndrome is a common and likely a multifactorial gastrointestinal disorder in which a disturbed brain-gut axis has been thought to have a mandatory role. Recent clinical and experimental studies imply that dietary factors may be more important in the pathogenesis of irritable bowel syn...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000181712.81657.0a
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Endoscopic ampullectomy has proven its safety and efficacy in multiple studies, making it the favorable option for the management of endoscopic ampullectomy. In this review, we plan to review the basic steps every endoscopist should be familiar with before undertaking endoscopic ampullectomy. RECENT ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/MOG.0000000000000657
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Ambulatory reflux monitoring is typically performed when esophageal symptoms do not respond to usual antireflux medications, or prior to invasive antireflux therapy. Although pH-based metrics have been the standard in defining esophageal reflux burden, novel impedance parameters have been introduced i...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000441
更新日期:2018-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Eosinophilic colitis is a rare condition, with a prevalence rate in the USA of 2-3/100 000 persons (0.003%), but diagnosed in 0.1% of biopsies in those colonoscoped for diarrhoea. Secondary colonic eosinophilia is more common and associated with systemic, colonic and infectious diseases. In this revie...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000492
更新日期:2019-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance. This review briefly summarizes advances in our understanding of the pathogenesis of nonalcoholic fatty liver disease and its prevalence, natural history and treatment....
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32801421a9
更新日期:2007-03-01 00:00:00
abstract::In spite of expanding knowledge of cellular and molecular mechanisms of intestinal inflammation, the etiology and pathogenesis of inflammatory bowel disease (IBD) remain obscure. The link between the environment and IBD is still circumstantial, but definite progress is occurring in defining genetic susceptibility loci...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-199907000-00003
更新日期:1999-07-01 00:00:00
abstract:PURPOSE OF REVIEW:There is a need for novel therapies for inflammatory bowel diseases (IBDs) that are well tolerated and effective. Currently, mesenchymal stem/stromal cells (MSCs) are being investigated in clinical trials for treatment of IBD. In this review, we update the recently published studies with an emphasis o...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000327
更新日期:2017-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This review will summarize the most significant work that contributed to the understanding of liver fibrosis progression and resolution, which in turn has yielded new areas of therapeutic targeting. RECENT FINDINGS:Liver fibrosis is the result of an imbalance between production and dissolution of ext...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/mog.0b013e3283279668
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Hyperplastic polyps, once considered to have no malignant potential, are now recognized to be part of a larger group of polyps known as serrated polyps. Serrated polyps can progress to CRC through an epigenetic pathway known as CpG Island Methylator Phenotype (CIMP), characterized by hypermethylation ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000495
更新日期:2019-01-01 00:00:00
abstract:PURPOSE OF REVIEW:We critically analyze existing endoscopy-based interventions for gastroesophageal reflux disease (GERD). The focus is on the effectiveness of available procedures and to delineate goals for future research. RECENT FINDINGS:Recent evaluations of the EndoCinch system reveal poor long-term results and n...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32832ad8b4
更新日期:2009-07-01 00:00:00
abstract::The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200009000-00002
更新日期:2000-09-01 00:00:00
abstract:PURPOSE OF THIS REVIEW:In the last 2 years, several studies have been published that will change the management of patients with Barrett's esophagus. In this review, we will discuss the most relevant studies as well as future prospects in this field. RECENT FINDINGS:Long-term follow-up studies have shown that to be co...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:
更新日期:2005-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This report reviews recent animal model and human studies associated with inflammatory responses in acute and chronic pancreatitis. RECENT FINDINGS:Animal model and limited human acute and chronic pancreatitis studies unravel the dynamic nature of the inflammatory processes and the ability of the imm...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000195
更新日期:2015-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Exciting new developments and applications of imaging techniques in pancreatic diseases have emerged. This review discusses these new advances and how they are improving our ability to diagnose malignancies and inflammatory lesions, to grade severity of pancreatitis, and to stage pancreatic cancer acc...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000174223.74783.1b
更新日期:2005-09-01 00:00:00
abstract::Water-soluble vitamins are required as enzyme cofactors in a wide variety of metabolic reactions. Riboflavin, niacin, and vitamin C are essential in redox reactions; thiamine and biotin are involved in macronutrient metabolism; and folate, vitamin B12, pyridoxine, and riboflavin play important roles in the regulation ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200303000-00003
更新日期:2003-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Availability of direct acting antivirals (DAAs) that demonstrate remarkable clinical efficacy and safety has revolutionized the ability to treat chronic infection with hepatitis C virus (HCV). An equal measure of clinical success has now been achieved in persons coinfected with HCV and the HIV, a hist...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000347
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Fermentable oligosaccharides disaccharides monosaccharides and polyols (FODMAP) dietary restriction ameliorates irritable bowel syndrome (IBS) symptoms; however, not all individuals with IBS respond. Given the gut microbiome's role in carbohydrate fermentation, investigators have evaluated whether the...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000608
更新日期:2020-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The goal is to review the most recent literature about biosimilars in inflammatory bowel disease (IBD), with emphasis on controversial regulatory issues. RECENT FINDINGS:Although biosimilars have been in use in Europe since 2005, the recent approval of CT-P13 (Remsima, Inflectra), a biosimilar of the...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000184
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To examine recent advances in the techniques and technologies of endoscopic resection of early gastric cancer. RECENT FINDINGS:Endoscopic mucosal resection of early gastric cancer with no risk of lymph node metastasis has been a standard technique in Japan and is increasingly becoming accepted and re...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000239873.06243.00
更新日期:2006-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Human colitis-associated cancers (CAC) represent a heterogeneous group of conditions in which multiple oncogenic pathways are involved. In this article, we review the latest studies using genetic, chemical, bacterial and innate immune-mediated experimental models of CAC. RECENT FINDINGS:Using the azo...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e328354cc36
更新日期:2012-07-01 00:00:00
abstract::Intestinal parasites continue to be a significant health problem in both developed and developing countries. In developed countries, protozoans are more commonly the cause of gastrointestinal infections than are helminths. Some protozoan parasites have stages in which, in addition to being resistant to chemicals used ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200301000-00005
更新日期:2003-01-01 00:00:00
abstract::Highlighting this year was the National Institutes of Health (NIH) State-of-the-Science Conference on endoscopic retrograde cholangiopancreatography. The panel addressed controversies in biliary endoscopy and set the framework for future funding for clinical research endeavors. With respect to biliary endoscopy, the l...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200305000-00013
更新日期:2003-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Submucosal endoscopy with mucosal flap (SEMF), a new diagnostic and therapeutic intervention of flexible endoscopy, has been examined from the perspective of developmental laboratory work, procedural details, and results of early clinical experiences. RECENT FINDINGS:Diagnostic natural orifice transl...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e328349cf8e
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Infection caused by ingestion of human-restricted Salmonella enterica serovars Typhi and Paratyphi predominantly affects the most impoverished sections of society. In this review, we describe recent advances made in estimating the burden of illness and the important role improved diagnostic tests may ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000021
更新日期:2014-01-01 00:00:00