The intestinal flora in inflammatory bowel disease: normal or abnormal?

abstract：PURPOSE OF REVIEW:The aim of this article is to review recently published studies presenting novel and relevant information on small intestinal motility. RECENT FINDINGS:The reviewed studies covered a variety of topics with several themes emerging. The presentation and causes of chronic intestinal dysmotility continue...

journal_title：Current opinion in gastroenterology

authors： Bratten JR,Jones MP

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been significant interest in gluten over the last decade, with an increase in interest of gluten-related disorders outside coeliac disease. Particularly, there has been a focus on the role of gluten in noncoeliac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS). There is signific...

journal_title：Current opinion in gastroenterology

authors： Rej A,Sanders DS

更新日期：2019-05-01 00:00:00

abstract：:Endoscopic management of biliary disease remains at the forefront of minimally invasive means of providing therapy, as well as contributing important diagnostic information in complex clinical scenarios. The authors review recent advances and reported trials of therapy and revisit important controversial issues. The m...

journal_title：Current opinion in gastroenterology

authors： Lew RJ,Kochman ML

更新日期：2000-09-01 00:00:00

abstract：:Gastric adenocarcinoma is the most common malignancy of the upper gastrointestinal tract. During the past two decades it has migrated toward the gastroesophageal junction. Gastroesophageal reflux and obesity may play a role. Recent research suggests that a number of biologic and molecular differences exist in patients...

journal_title：Current opinion in gastroenterology

authors： Yao JC,Ajani JA

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To critically appraise evidence on probiotic use for prevention and treatment of diarrhea in children and adults. RECENT FINDINGS:Several randomized controlled trials and meta-analyses suggested that probiotics are effective in primary and secondary prevention of gastroenteritis and its treatment. Se...

journal_title：Current opinion in gastroenterology

authors： Guarino A,Lo Vecchio A,Canani RB

更新日期：2009-01-01 00:00:00

abstract：:Molecular-phylogenetic methods have revolutionized the analysis of complex microbial communities. Polymerase chain reaction amplification and phylogenetic analysis of small-subunit ribosomal RNA gene sequences allow microbes to be identified objectively, even in the absence of cultivation. Furthermore, the sequence in...

journal_title：Current opinion in gastroenterology

authors： Frank DN,Pace NR

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:One of the significant limitations to the investigation of inflammatory bowel disease (IBD) in humans is the impossibility of studying this condition from the beginning of the disease process to understand the individual contribution of the various microbiological and immunological components to its p...

journal_title：Current opinion in gastroenterology

authors： Wu H,Shen B

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review new advances in gastric interventional endoscopy. RECENT FINDINGS:Implementation of gastric endoscopy as a therapeutic option in obesity, gastric cancer, and gastroparesis. SUMMARY:Less invasive new gastric endoscopic procedures can potentially replace currently offered laparoscopic approa...

journal_title：Current opinion in gastroenterology

authors： Mahmoud M,Holzwanger E,Wassef W

更新日期：2017-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This article highlights recent advances in viral hepatitis published from December 2003 to November 2004. Studies reporting novel and clinically relevant findings were selected after a PubMed search. The aim is to provide an up-to-date summary of important developments in viral hepatitis. RECENT FIND...

journal_title：Current opinion in gastroenterology

authors： Fung SK,Lok AS

更新日期：2005-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The most relevant studies concerning the diagnosis of esophageal varices, primary and secondary prophylaxis and treatment of variceal bleeding published in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to studies on the noninvasive or minimally invasive ...

journal_title：Current opinion in gastroenterology

authors： de Franchis R,Dell'Era A

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to highlight literature published during the last year in the context of previous knowledge. RECENT FINDINGS:A number of novel techniques - high-resolution manometry, esophageal electrical impedance and intra-luminal ultrasound imaging - have improved our understanding of e...

journal_title：Current opinion in gastroenterology

authors： Dogan I,Mittal RK

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To consider observations suggesting that the bacterial protein flagellin, the primary structural component of flagella, plays a major role in mediating gut inflammation associated with infection by enteric pathogens and in inflammatory bowel disease. RECENT FINDINGS:Biochemical dissection of an in-vi...

journal_title：Current opinion in gastroenterology

authors： Gewirtz AT

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent advances and novel insights into the mechanistic events that may link commensal microbiota and host innate immunity in the pathophysiology of intestinal inflammation and neoplasia. Unanswered questions are discussed and future perspectives in the field are highlighted. R...

journal_title：Current opinion in gastroenterology

authors： Cario E

更新日期：2013-01-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) affects many patients and has a negative effect on quality of life. Along with the increasing prevalence of GERD is an increase in GERD-related complications, including Barrett esophagus and esophageal adenocarcinoma. The past year has yielded new insights into the pathophysiolog...

journal_title：Current opinion in gastroenterology

authors： Sifrim D,Zerbib F

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent advances in the techniques and technologies of endoscopic resection of early gastric cancer. RECENT FINDINGS:Endoscopic mucosal resection of early gastric cancer with no risk of lymph node metastasis has been a standard technique in Japan and is increasingly becoming accepted and re...

journal_title：Current opinion in gastroenterology

authors： Gotoda T

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The composition of activated adipose tissue with adipocytes secreting a broad spectrum of immune-modulatory adipokines next to adipose tissue-derived stromal cells and professional immune effector cells in the visceral fat creates a complex network of inflammatory processes shaping local immune respon...

journal_title：Current opinion in gastroenterology

authors： Paeschke A,Erben U,Kredel LI,Kühl AA,Siegmund B

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:We critically analyze existing endoscopy-based interventions for gastroesophageal reflux disease (GERD). The focus is on the effectiveness of available procedures and to delineate goals for future research. RECENT FINDINGS:Recent evaluations of the EndoCinch system reveal poor long-term results and n...

journal_title：Current opinion in gastroenterology

authors： Jafri SM,Arora G,Triadafilopoulos G

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic mechanisms. RECENT FI...

journal_title：Current opinion in gastroenterology

authors： Kleibeuker JH,Thijs JC

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The introduction of novel molecular imaging modalities that can not only define disease states on the basis of structural changes and morphology, but also allow in-vivo visualization and characterization of molecular and biochemical alterations on a cellular level add a new dimension to our current di...

journal_title：Current opinion in gastroenterology

authors： Atreya R,Neurath MF

更新日期：2014-11-01 00:00:00

abstract：:Traditional anatomic pathology studies and molecular investigations both contributed to the breadth of current information in the field of liver pathology this year. Techniques such as reverse transcription polymerase chain reaction can identify recurrence of hepatitis C virus infection in the liver as early as 5 days...

journal_title：Current opinion in gastroenterology

authors： Lefkowitch JH

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Endoscopic approaches to obesity may help fulfill the unmet need of over half the US adult population who would benefit from therapy for obesity but are not receiving it. Endoluminal approaches have the potential to be more efficacious than antiobesity medications and have a lower risk-cost profile co...

journal_title：Current opinion in gastroenterology

authors： Kumbhari V,Oberbach A,Nimgaonkar A

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Availability of direct acting antivirals (DAAs) that demonstrate remarkable clinical efficacy and safety has revolutionized the ability to treat chronic infection with hepatitis C virus (HCV). An equal measure of clinical success has now been achieved in persons coinfected with HCV and the HIV, a hist...

journal_title：Current opinion in gastroenterology

authors： Meissner EG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Catheter-related bloodstream infections (CRBSIs) account for a major source of morbidity in children with intestinal failure. Many of these patients require long-term central venous access, placing them at significant risk for these infections. The purpose of this review is to highlight the most curre...

journal_title：Current opinion in gastroenterology

authors： Piper HG,Wales PW

更新日期：2013-01-01 00:00:00

abstract：:A part of living in a new and exciting era for the biologic sciences and medicine, novel high throughput tools allow exploration of the human genome in an unprecedented manner. This "information revolution" is fueled by the study of genome-wide expression profiles for complex biologic and pathophysiologic conditions u...

journal_title：Current opinion in gastroenterology

authors： Fernandez-Zapico ME,Callahan G,Delgado S,Urrutia R

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance. This review briefly summarizes advances in our understanding of the pathogenesis of nonalcoholic fatty liver disease and its prevalence, natural history and treatment....

journal_title：Current opinion in gastroenterology

authors： Neuschwander-Tetri BA

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent progress on endoscopic diagnosis and treatment of esophageal high-grade intraepithelial neoplasia and early adenocarcinoma and critically analyzes the literature in the context of preexisting scientific data. RECENT FINDINGS:Narrow band imaging and computed virtual chrom...

journal_title：Current opinion in gastroenterology

authors： Seewald S,Ang TL,Groth S,Zhong Y,Bertschinger P,Altorfer J,Thonke F,Soehendra N

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this brief review is to provide an up-to-date view of the role played by α-smooth muscle actin-positive cancer-associated fibroblastic cells in promoting intrahepatic cholangiocarcinoma progression. RECENT FINDINGS:An increase in α-smooth muscle actin-positive cancer-associated fibroblasti...

journal_title：Current opinion in gastroenterology

authors： Sirica AE,Campbell DJ,Dumur CI

更新日期：2011-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To review important manuscripts published over the previous 2 years relative to sphincter of Oddi dysfunction (SOD). RECENT FINDINGS:The long-term outcomes of the Evaluating Predictors and Interventions of SOD (EPISOD) trial further substantiated results from the initial EPISOD study, reinforcing tha...

journal_title：Current opinion in gastroenterology

authors： Hyun JJ,Kozarek RA

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...

journal_title：Current opinion in gastroenterology

authors： Takakura WR,Tabibian JH,Bowlus CL

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary biliary cholangitis (PBC) is a rare autoimmune liver disease that increasingly is diagnosed at early stages of disease. Although survival has improved, a majority suffers from one or more symptom complexes associated with PBC. Much remains unknown about the mechanisms, significance, or effecti...

journal_title：Current opinion in gastroenterology

authors： Kuo A,Kuo A,Bowlus CL

更新日期：2016-05-01 00:00:00