Gastroesophageal reflux disease.

abstract：PURPOSE OF REVIEW:To consider observations suggesting that the bacterial protein flagellin, the primary structural component of flagella, plays a major role in mediating gut inflammation associated with infection by enteric pathogens and in inflammatory bowel disease. RECENT FINDINGS:Biochemical dissection of an in-vi...

journal_title：Current opinion in gastroenterology

authors： Gewirtz AT

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Endoscopic approaches to obesity may help fulfill the unmet need of over half the US adult population who would benefit from therapy for obesity but are not receiving it. Endoluminal approaches have the potential to be more efficacious than antiobesity medications and have a lower risk-cost profile co...

journal_title：Current opinion in gastroenterology

authors： Kumbhari V,Oberbach A,Nimgaonkar A

更新日期：2015-09-01 00:00:00

abstract：:Highlighting this year was the National Institutes of Health (NIH) State-of-the-Science Conference on endoscopic retrograde cholangiopancreatography. The panel addressed controversies in biliary endoscopy and set the framework for future funding for clinical research endeavors. With respect to biliary endoscopy, the l...

journal_title：Current opinion in gastroenterology

authors： Beilstein MC,Kochman ML

更新日期：2003-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the recent literature on endoscopic spray cryotherapy for the treatment of Barrett's esophagus and esophageal cancer. RECENT FINDINGS:Endoscopic spray cryotherapy is a relatively new ablative modality for the treatment of gastrointestinal diseases. Spray cryotherapy rapidly cools tissues...

journal_title：Current opinion in gastroenterology

authors： Greenwald BD,Dumot JA

更新日期：2011-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Enteral nutrition is now the preferred route of nutritional support in malnourished and ICU patients. Studies providing evidence of its efficacy, techniques of administration, and outcome are appearing daily in the literature. This review presents the most important publications in this area and criti...

journal_title：Current opinion in gastroenterology

authors： Jeejeebhoy KN

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Exciting new developments and applications of imaging techniques in pancreatic diseases have emerged. This review discusses these new advances and how they are improving our ability to diagnose malignancies and inflammatory lesions, to grade severity of pancreatitis, and to stage pancreatic cancer acc...

journal_title：Current opinion in gastroenterology

authors： Kwon RS,Brugge WR

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will assess recent clinical and mechanistic data examining glutamine's ability to reduce morbidity and mortality in critical illness. RECENT FINDINGS:Updated metaanalysis data reveal a significant benefit of glutamine supplementation on mortality, length of stay, and infectious morbidity ...

journal_title：Current opinion in gastroenterology

authors： Wischmeyer PE

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:There have been considerable advances in our understanding of the molecular pathogenesis of enteropathogenic Escherichia coli and enterohemorrhagic E. coli infection. Given the difficulty of infecting laboratory mice with these diarrhea-causing pathogens, a growing number of studies have found the mur...

journal_title：Current opinion in gastroenterology

authors： Borenshtein D,McBee ME,Schauer DB

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Over the past 15 years, great strides have been made in the nonsurgical management of malignant large bowel obstruction. Progress continues, particularly in the area of self-expanding metal stents. The purpose of this review is to assess the available endoscopic techniques for colonic decompression an...

journal_title：Current opinion in gastroenterology

authors： Dekovich AA

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Irritable bowel syndrome is a common and likely a multifactorial gastrointestinal disorder in which a disturbed brain-gut axis has been thought to have a mandatory role. Recent clinical and experimental studies imply that dietary factors may be more important in the pathogenesis of irritable bowel syn...

journal_title：Current opinion in gastroenterology

authors： Kalliomäki MA

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Autoimmune hepatitis (AIH) is a chronic disease characterized by a lymphocyte infiltrate in the liver. For decades, nonspecific immunosuppression has been used to limit chronic liver inflammation. The high risk of relapse, the treatments side effects, and the significant number of refractory patients ...

journal_title：Current opinion in gastroenterology

authors： Cardon A,Conchon S,Renand A

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Historically, surgical treatment of choledochal cyst consisted of cyst enterostomy. However, incomplete cyst excision can result in recurrent symptoms and malignant transformation within the cyst remnant. Accordingly, management of choledochal cyst now includes complete cyst excision whenever possible...

journal_title：Current opinion in gastroenterology

authors： Ronnekleiv-Kelly SM,Soares KC,Ejaz A,Pawlik TM

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Nod-like receptors (NLRs) are intracellular innate immune sensors of microbes and danger signals that control multiple aspects of inflammatory responses. We review the evidence that highlights the critical importance of NLRs in the host response to intestinal pathogens. Moreover, we discuss the potent...

journal_title：Current opinion in gastroenterology

authors： Robertson SJ,Girardin SE

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The most relevant studies concerning the diagnosis of esophageal varices, primary and secondary prophylaxis and treatment of variceal bleeding published in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to studies on the noninvasive or minimally invasive ...

journal_title：Current opinion in gastroenterology

authors： de Franchis R,Dell'Era A

更新日期：2007-07-01 00:00:00

abstract：:Intestinal parasites continue to be a significant health problem in both developed and developing countries. In developed countries, protozoans are more commonly the cause of gastrointestinal infections than are helminths. Some protozoan parasites have stages in which, in addition to being resistant to chemicals used ...

journal_title：Current opinion in gastroenterology

authors： Harp JA

更新日期：2003-01-01 00:00:00

abstract：:Interesting advances occurred recently in nutrient absorption. Kinetics of triacylglycerol appearance in endoplasmic reticulum, Golgi apparatus, and lymph support the hypothesis that endoplasmic reticulum-to-Golgi transport is rate-limiting for lipid absorption. Apolipoprotein B does not appear necessary for initial f...

journal_title：Current opinion in gastroenterology

authors： Nutting DF,Kumar NS,St Hilaire RJ,Mansbach CM 2nd

更新日期：1999-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The remarkable resistance of the mucosal lining the upper gastrointestinal tract to concentrated gastric acid remains one of the biggest unsolved mysteries of upper gastrointestinal physiology. Even with the discovery of the involvement of Helicobacter pylori in gastroduodenal injury, the mechanism by...

journal_title：Current opinion in gastroenterology

authors： Bi LC,Kaunitz JD

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to review recently published studies presenting novel and relevant information on small intestinal motility. RECENT FINDINGS:The reviewed studies covered a variety of topics with several themes emerging. The presentation and causes of chronic intestinal dysmotility continue...

journal_title：Current opinion in gastroenterology

authors： Bratten JR,Jones MP

更新日期：2007-03-01 00:00:00

abstract：:This article provides an overview of advances in understanding the cellular and molecular mechanisms and regulation of intestinal absorption processes of vitamins. The vitamins covered are the water-soluble vitamins folic acid, cobalamin (vitamin B12), biotin, pantothenic acid, and thiamine (vitamin B1) and the lipid-...

journal_title：Current opinion in gastroenterology

authors： Said HM,Kumar C

更新日期：1999-03-01 00:00:00

abstract：:Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural ...

journal_title：Current opinion in gastroenterology

authors： Nguyen NQ,Holloway RH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Fermentable oligosaccharides disaccharides monosaccharides and polyols (FODMAP) dietary restriction ameliorates irritable bowel syndrome (IBS) symptoms; however, not all individuals with IBS respond. Given the gut microbiome's role in carbohydrate fermentation, investigators have evaluated whether the...

journal_title：Current opinion in gastroenterology

authors： Chumpitazi BP

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Taking advantage of their rapid growth and capacity for continuous genetic adaptation, prokaryotes have colonized all possible ecological environments on earth, including the body surfaces of eukaryotes and their gastrointestinal tract. The mammalian gut contains a complex community of 10 bacteria wit...

journal_title：Current opinion in gastroenterology

authors： Gaboriau-Routhiau V,Lécuyer E,Cerf-Bensussan N

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic liver disease (CLD) causes significant morbidity and mortality, mainly due to complications [hepatic encephalopathy, ascites, hepatorenal syndrome (HRS) and esophageal variceal hemorrhage (EVH)]. Studies of the complications, management and outcomes in patients with CLD over the last 18 months...

journal_title：Current opinion in gastroenterology

authors： Rahimi RS,Rockey DC

更新日期：2011-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Inflammatory bowel disease commonly affects women during the childbearing years, and young couples are often concerned about the potential effects of inflammatory bowel disease on fertility, pregnancy, and the fetus. This review will critically consider advances over the past 2 years in our knowledge ...

journal_title：Current opinion in gastroenterology

authors： Katz JA

更新日期：2004-07-01 00:00:00

abstract：:Colon carcinogenesis is a multistep process that involves deletions, mutations, and changes in expression of genes that regulate growth, differentiation, and apoptosis. Hyperproliferation can initiate dysplastic growth, resulting in accumulation of genetic defects and progression of colon cancer. Although genetic inst...

journal_title：Current opinion in gastroenterology

authors： Singh P,Dai B,Wu H,Owlia A

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In both Crohn's disease and ulcerative colitis, the tissue damage results from an inappropriate or exaggerated immune response to antigens of the gut microflora. This review summarizes current knowledge regarding the role of immune-inflammatory mediators in the pathogenesis of inflammatory bowel disea...

journal_title：Current opinion in gastroenterology

authors： Monteleone G,Fina D,Caruso R,Pallone F

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance. This review briefly summarizes advances in our understanding of the pathogenesis of nonalcoholic fatty liver disease and its prevalence, natural history and treatment....

journal_title：Current opinion in gastroenterology

authors： Neuschwander-Tetri BA

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Catheter-related bloodstream infections (CRBSIs) account for a major source of morbidity in children with intestinal failure. Many of these patients require long-term central venous access, placing them at significant risk for these infections. The purpose of this review is to highlight the most curre...

journal_title：Current opinion in gastroenterology

authors： Piper HG,Wales PW

更新日期：2013-01-01 00:00:00

abstract：:The treatment of inflammatory bowel disease is a continually evolving area and a major focus of the current literature in gastroenterology. As further information is gained in the areas of etiology, pathophysiology, and natural history of the disease, new agents are developed, and management strategies are revised. Th...

journal_title：Current opinion in gastroenterology

authors： Nash CL,Sutherland LR

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this study is to provide an overview of the role of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in inflammatory bowel disease (IBD). RECENT FINDINGS:Human genetic studies have identified several UPR-related genes and autophagy-related genes as IBD risk loc...

journal_title：Current opinion in gastroenterology

authors： Hosomi S,Kaser A,Blumberg RS

更新日期：2015-01-01 00:00:00