Primary endoscopic therapies for obesity and metabolic diseases.

abstract：PURPOSE OF REVIEW:This review discusses the advances in the pathophysiology, diagnosis, and management of the complications of portal hypertension that have occurred in the past year. RECENT FINDINGS:The specific topics reviewed are the pathophysiology of portal hypertension (including recent findings regarding intrah...

journal_title：Current opinion in gastroenterology

authors： Garcia-Tsao G

更新日期：2004-05-01 00:00:00

abstract：:Recently, much progress has been made in the field of tumor immunology. Much of this work has focused on understanding and exploiting the innate immune response to tumor cells. A novel human receptor-ligand system that mediates natural killer (NK) and gammadelta T-cell killing of carcinoma cells has been identified, a...

journal_title：Current opinion in gastroenterology

authors： Golby SJ,Spencer J

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Significant advances in the pathophysiology, diagnosis and management of the complications of portal hypertension that have occurred in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to experimental studies aimed at modifying the factors that lead to port...

journal_title：Current opinion in gastroenterology

authors： Garcia-Tsao G

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Availability of direct acting antivirals (DAAs) that demonstrate remarkable clinical efficacy and safety has revolutionized the ability to treat chronic infection with hepatitis C virus (HCV). An equal measure of clinical success has now been achieved in persons coinfected with HCV and the HIV, a hist...

journal_title：Current opinion in gastroenterology

authors： Meissner EG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The human gut is the natural habitat for a large and dynamic bacterial community. There is a substantial body of evidence implicating the resident flora in the pathogenesis of chronic intestinal inflammation. This review discusses the possible role of a microbial imbalance in the pathophysiology of in...

journal_title：Current opinion in gastroenterology

authors： Guarner F

更新日期：2005-07-01 00:00:00

abstract：:Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural ...

journal_title：Current opinion in gastroenterology

authors： Nguyen NQ,Holloway RH

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in our understanding of lymphoid tissue development has led to an appreciation of the variety of these structures in the intestinal mucosa. This knowledge has translated into more critical analysis of the function of mucosal lymphoid tissues and may lead to manipulation of development of thes...

journal_title：Current opinion in gastroenterology

authors： Newberry RD

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Functional dyspepsia is a common disorder, most of the time of unknown etiology and with variable pathophysiology. Therapy has been and still is largely empirical. Data from recent studies provide new clues for targeted therapy based on knowledge of etiology and pathophysiologic mechanisms. RECENT FI...

journal_title：Current opinion in gastroenterology

authors： Kleibeuker JH,Thijs JC

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Eosinophilic colitis is a rare condition, with a prevalence rate in the USA of 2-3/100 000 persons (0.003%), but diagnosed in 0.1% of biopsies in those colonoscoped for diarrhoea. Secondary colonic eosinophilia is more common and associated with systemic, colonic and infectious diseases. In this revie...

journal_title：Current opinion in gastroenterology

authors： Walker MM,Potter MD,Talley NJ

更新日期：2019-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Barrett's esophagus is the premalignant condition for esophageal cancer and the diagnosis of esophageal adenocarcinoma on index endoscopy is increasing. Many advanced endoscopic techniques are available and aim to identify Barrett's esophagus-associated neoplasia earlier, thereby preventing progressio...

journal_title：Current opinion in gastroenterology

authors： Sutton RA,Sharma P

更新日期：2019-09-01 00:00:00

abstract：:Over the last year, several interesting studies have been published on the treatment of esophageal carcinoma. Surprisingly, none of them was a randomized phase III trial. The debate on the necessary extent of a potentially curative surgical resection is ongoing. After initially disappointing results, the innovative te...

journal_title：Current opinion in gastroenterology

authors： van Lanschot JJ,González González D,Richel DJ

更新日期：2001-07-01 00:00:00

abstract：:Diarrhea is a common sequela of deregulated immune pathways underlying the wide range of intestinal acute and chronic diseases. The ongoing investigation of novel immune components and susceptibility factors allows better understanding of these pathologic mechanisms and continues to advance therapeutic options. ...

journal_title：Current opinion in gastroenterology

authors： Lahav M,Chang E

更新日期：2002-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Immunoglobulin G4-associated cholangitis is a recently identified clinical entity characterized by infiltration of immunoglobulin G4 -bearing plasma cells in bile ducts and other affected tissues. This review is focused mainly on the most recent studies published during the last 2 years that have incr...

journal_title：Current opinion in gastroenterology

authors： Björnsson E

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the recent literature on endoscopic spray cryotherapy for the treatment of Barrett's esophagus and esophageal cancer. RECENT FINDINGS:Endoscopic spray cryotherapy is a relatively new ablative modality for the treatment of gastrointestinal diseases. Spray cryotherapy rapidly cools tissues...

journal_title：Current opinion in gastroenterology

authors： Greenwald BD,Dumot JA

更新日期：2011-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There have been considerable advances in our understanding of the molecular pathogenesis of enteropathogenic Escherichia coli and enterohemorrhagic E. coli infection. Given the difficulty of infecting laboratory mice with these diarrhea-causing pathogens, a growing number of studies have found the mur...

journal_title：Current opinion in gastroenterology

authors： Borenshtein D,McBee ME,Schauer DB

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Endoscopic ampullectomy has proven its safety and efficacy in multiple studies, making it the favorable option for the management of endoscopic ampullectomy. In this review, we plan to review the basic steps every endoscopist should be familiar with before undertaking endoscopic ampullectomy. RECENT ...

journal_title：Current opinion in gastroenterology

authors： Klair JS,Irani S,Kozarek R

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will summarize the most significant work that contributed to the understanding of liver fibrosis progression and resolution, which in turn has yielded new areas of therapeutic targeting. RECENT FINDINGS:Liver fibrosis is the result of an imbalance between production and dissolution of ext...

journal_title：Current opinion in gastroenterology

authors： Jiao J,Friedman SL,Aloman C

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Morbid obesity is an epidemic in the United States and parts of Europe, with severe health consequences. As the number of patients undergoing bariatric surgery has increased dramatically, it is crucial for the gastroenterologist caring for these patients to have a better understanding of the procedure...

journal_title：Current opinion in gastroenterology

authors： Lee CW,Kelly JJ,Wassef WY

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing use of small bowel endoscopy unravels ulcers in a relevant number of patients. Although often attributed to inflammatory bowel disease (IBD), these ulcers may be unspecific or caused by a variety of other diseases. This review summarizes the recent literature related to differential diagnos...

journal_title：Current opinion in gastroenterology

authors： Keuchel M,Kurniawan N,Baltes P

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Cytokines of the intestinal microenvironment largely dictate immunological responses after mucosal insults and the dominance of homeostatic or proinflammatory pathways. This review presents important recent studies on the role of specific cytokines in the pathogenesis of intestinal inflammation. RECE...

journal_title：Current opinion in gastroenterology

authors： Bamias G,Cominelli F

更新日期：2016-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Food addiction has been implicated as a putative causal factor in chronic overeating, binge eating, and obesity. The concept of food addiction has been controversial historically due to definitional and conceptual difficulties and to a lack of rigorous scientific data. RECENT FINDINGS:Support for the...

journal_title：Current opinion in gastroenterology

authors： Corsica JA,Pelchat ML

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal is to review the most recent literature about biosimilars in inflammatory bowel disease (IBD), with emphasis on controversial regulatory issues. RECENT FINDINGS:Although biosimilars have been in use in Europe since 2005, the recent approval of CT-P13 (Remsima, Inflectra), a biosimilar of the...

journal_title：Current opinion in gastroenterology

authors： Gomollón F

更新日期：2015-07-01 00:00:00

abstract：:The treatment of inflammatory bowel disease is a continually evolving area and a major focus of the current literature in gastroenterology. As further information is gained in the areas of etiology, pathophysiology, and natural history of the disease, new agents are developed, and management strategies are revised. Th...

journal_title：Current opinion in gastroenterology

authors： Nash CL,Sutherland LR

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Small bowel capsule endoscopy (SBCE) was introduced 13 years ago by Given Imaging (Yokneam, Israel). It has become one of the most important investigational tools of the small bowel. The capsule is swallowed with water after a 12 h fast, propelled via peristalsis through the gastrointestinal tract and...

journal_title：Current opinion in gastroenterology

authors： Eliakim R

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary biliary cholangitis (PBC) is a rare autoimmune liver disease that increasingly is diagnosed at early stages of disease. Although survival has improved, a majority suffers from one or more symptom complexes associated with PBC. Much remains unknown about the mechanisms, significance, or effecti...

journal_title：Current opinion in gastroenterology

authors： Kuo A,Kuo A,Bowlus CL

更新日期：2016-05-01 00:00:00

abstract：:In spite of expanding knowledge of cellular and molecular mechanisms of intestinal inflammation, the etiology and pathogenesis of inflammatory bowel disease (IBD) remain obscure. The link between the environment and IBD is still circumstantial, but definite progress is occurring in defining genetic susceptibility loci...

journal_title：Current opinion in gastroenterology

authors： Katz JA,Itoh J,Fiocchi C

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The 2009 review on small intestinal ion transport, in this series, focused on recent advances in duodenal bicarbonate secretion, the importance of scaffolding proteins and the pathophysiology of inflammation-associated diarrhea. The current review focuses on advances in ion-coupled solute transport, t...

journal_title：Current opinion in gastroenterology

authors： Venkatasubramanian J,Ao M,Rao MC

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Hyperplastic polyps, once considered to have no malignant potential, are now recognized to be part of a larger group of polyps known as serrated polyps. Serrated polyps can progress to CRC through an epigenetic pathway known as CpG Island Methylator Phenotype (CIMP), characterized by hypermethylation ...

journal_title：Current opinion in gastroenterology

authors： Lindholm CR,Anderson JC,Srivastava A

更新日期：2019-01-01 00:00:00

abstract：:Molecular-phylogenetic methods have revolutionized the analysis of complex microbial communities. Polymerase chain reaction amplification and phylogenetic analysis of small-subunit ribosomal RNA gene sequences allow microbes to be identified objectively, even in the absence of cultivation. Furthermore, the sequence in...

journal_title：Current opinion in gastroenterology

authors： Frank DN,Pace NR

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Esophageal varices and Mallory Weiss syndrome are the two major esophageal bleeding disorders. Although there have been major breakthroughs in the treatment of peptic ulcer bleeding, the management of esophageal bleeding disorders remains a challenging problem. This review focuses on studies published...

journal_title：Current opinion in gastroenterology

authors： Wu JC,Chan FK

更新日期：2004-07-01 00:00:00