Hepatic fibrosis.

abstract：PURPOSE OF REVIEW:This article highlights recent advances in viral hepatitis published from December 2003 to November 2004. Studies reporting novel and clinically relevant findings were selected after a PubMed search. The aim is to provide an up-to-date summary of important developments in viral hepatitis. RECENT FIND...

journal_title：Current opinion in gastroenterology

authors： Fung SK,Lok AS

更新日期：2005-05-01 00:00:00

abstract：:The neurohormonal control of pancreatic exocrine secretion is a complex interaction of multiple pathways involving a large number of gut hormones, neurotransmitters, and neuropeptides. Recent studies have elucidated a role for cholecystokinin in the regulation of bicarbonate and fluid secretion from pancreatic duct ce...

journal_title：Current opinion in gastroenterology

authors： Nathan JD,Liddle RA

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to highlight literature published during the last year in the context of previous knowledge. RECENT FINDINGS:A number of novel techniques - high-resolution manometry, esophageal electrical impedance and intra-luminal ultrasound imaging - have improved our understanding of e...

journal_title：Current opinion in gastroenterology

authors： Dogan I,Mittal RK

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...

journal_title：Current opinion in gastroenterology

authors： Takakura WR,Tabibian JH,Bowlus CL

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Research in celiac disease is unraveling new findings at a high rate, and major advances seem to occur in all areas such as genetics, environmental factor, pathophysiology, and even prospective therapeutic implications. RECENT FINDINGS:New insight is being gained into the interplay between genetic an...

journal_title：Current opinion in gastroenterology

authors： Guandalini S,Setty M

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Noroviruses (NoVs) are the most common cause of epidemic and sporadic cases of acute gastroenteritis worldwide. This review summarizes recent NoV disease burden estimates, epidemiology findings and provides an update on virus-like particle (VLP) vaccine studies. RECENT FINDINGS:NoVs are the leading c...

journal_title：Current opinion in gastroenterology

authors： Ramani S,Atmar RL,Estes MK

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Submucosal endoscopy with mucosal flap (SEMF), a new diagnostic and therapeutic intervention of flexible endoscopy, has been examined from the perspective of developmental laboratory work, procedural details, and results of early clinical experiences. RECENT FINDINGS:Diagnostic natural orifice transl...

journal_title：Current opinion in gastroenterology

authors： Sumiyama K,Gostout CJ

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Esophageal varices and Mallory Weiss syndrome are the two major esophageal bleeding disorders. Although there have been major breakthroughs in the treatment of peptic ulcer bleeding, the management of esophageal bleeding disorders remains a challenging problem. This review focuses on studies published...

journal_title：Current opinion in gastroenterology

authors： Wu JC,Chan FK

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The past few years have seen an increase in the number of research and clinical groups around the world using high-resolution manometry (HRM) to record contractile activity in the anorectum and colon. Yet despite the uptake and growing number of publications, the clinical utility and potential advanta...

journal_title：Current opinion in gastroenterology

authors： Dinning PG,Carrington EV,Scott SM

更新日期：2016-01-01 00:00:00

abstract：:The elucidation of metabolic pathways and the genetic basis for diseases of the liver continues to increase our understanding of disease pathogenesis and advance treatment options. This selective review covers a wide range of subjects, from the identification of novel proteins and the importance of specific transport ...

journal_title：Current opinion in gastroenterology

authors： Schilsky ML

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a need for novel therapies for inflammatory bowel diseases (IBDs) that are well tolerated and effective. Currently, mesenchymal stem/stromal cells (MSCs) are being investigated in clinical trials for treatment of IBD. In this review, we update the recently published studies with an emphasis o...

journal_title：Current opinion in gastroenterology

authors： Dave M,Jaiswal P,Cominelli F

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been significant interest in gluten over the last decade, with an increase in interest of gluten-related disorders outside coeliac disease. Particularly, there has been a focus on the role of gluten in noncoeliac gluten sensitivity (NCGS) and irritable bowel syndrome (IBS). There is signific...

journal_title：Current opinion in gastroenterology

authors： Rej A,Sanders DS

更新日期：2019-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize published research on pancreatic surgery over the past year. RECENT FINDINGS:Improvements in the treatment of patients with acute gallstone pancreatitis with regards to the timing of ERCP and cholecystectomy as well as management of pancreatic pseudocysts have been reported. It is often ...

journal_title：Current opinion in gastroenterology

authors： Donahue TR,Reber HA

更新日期：2010-09-01 00:00:00

abstract：:This year's review has been divided into five sections: The first describes the natural history of drug-induced liver disease, the second discusses the issue of placebo-related increases in liver-associated enzymes, the third describes agents newly reported to cause hepatic injury, the fourth discusses new reports of ...

journal_title：Current opinion in gastroenterology

authors： Mayoral W,Lewis JH

更新日期：2000-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the advances in diagnostic modalities and management options for defecatory dysfunction and highlight the areas in need of further research. RECENT FINDINGS:The diagnostic utility of high-resolution anorectal manometry (ARM), which has emerged as a promising tool for the diagnosis of def...

journal_title：Current opinion in gastroenterology

authors： Neshatian L

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The 2009 review on small intestinal ion transport, in this series, focused on recent advances in duodenal bicarbonate secretion, the importance of scaffolding proteins and the pathophysiology of inflammation-associated diarrhea. The current review focuses on advances in ion-coupled solute transport, t...

journal_title：Current opinion in gastroenterology

authors： Venkatasubramanian J,Ao M,Rao MC

更新日期：2010-03-01 00:00:00

abstract：:Intestinal parasites continue to be a significant health problem in both developed and developing countries. In developed countries, protozoans are more commonly the cause of gastrointestinal infections than are helminths. Some protozoan parasites have stages in which, in addition to being resistant to chemicals used ...

journal_title：Current opinion in gastroenterology

authors： Harp JA

更新日期：2003-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To outline the recommended course of action when a subepithelial lesion is encountered during upper endoscopy. It will focus on the endoscopic and endosonographic features common to gastrointestinal stromal tumors, and the optimal tests performed to confirm the diagnosis of a gastrointestinal stromal ...

journal_title：Current opinion in gastroenterology

authors： Rodriguez SA,Faigel DO

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Availability of direct acting antivirals (DAAs) that demonstrate remarkable clinical efficacy and safety has revolutionized the ability to treat chronic infection with hepatitis C virus (HCV). An equal measure of clinical success has now been achieved in persons coinfected with HCV and the HIV, a hist...

journal_title：Current opinion in gastroenterology

authors： Meissner EG

更新日期：2017-05-01 00:00:00

abstract：:The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...

journal_title：Current opinion in gastroenterology

authors： Logsdon CD

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review article, we address emerging evidence for the medical and surgical treatment of the hospitalized patient with ulcerative colitis. RECENT FINDINGS:Ulcerative colitis is a chronic inflammatory disease involving the colon and rectum. About one-fifth of patients will be hospitalized from u...

journal_title：Current opinion in gastroenterology

authors： Levy LC,Coburn ES,Choi S,Holubar SD

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The gastroduodenum has multiple means by which it resists injury from intrinsic and extrinsic factors, including gastric acid, nonsteroidal anti-inflammatory drugs, and Helicobacter pylori. We review recent insights into the mechanisms by which the gastroduodenum resists injury and discuss factors con...

journal_title：Current opinion in gastroenterology

authors： Nayeb-Hashemi H,Kaunitz JD

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Immunoglobulin G4-associated cholangitis is a recently identified clinical entity characterized by infiltration of immunoglobulin G4 -bearing plasma cells in bile ducts and other affected tissues. This review is focused mainly on the most recent studies published during the last 2 years that have incr...

journal_title：Current opinion in gastroenterology

authors： Björnsson E

更新日期：2008-05-01 00:00:00

abstract：:Viral hepatitis is still one of the most common causes of acute and chronic liver disease worldwide. Major advances have been made in our knowledge of these diseases, many during the past year. Molecular biology and clinical studies have improved our understanding of the mechanisms of antiviral drugs, as well as viral...

journal_title：Current opinion in gastroenterology

authors： Regev A,Schiff ER

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic liver disease (CLD) causes significant morbidity and mortality, mainly due to complications [hepatic encephalopathy, ascites, hepatorenal syndrome (HRS) and esophageal variceal hemorrhage (EVH)]. Studies of the complications, management and outcomes in patients with CLD over the last 18 months...

journal_title：Current opinion in gastroenterology

authors： Rahimi RS,Rockey DC

更新日期：2011-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiologic imaging of the large intestine continues to evolve and expand the potential for noninvasive diagnosis. The aim of this review is to provide an update on current and emerging clinical capabilities for a variety of radiologic diagnostic imaging tools for evaluating the colon and rectum. RECE...

journal_title：Current opinion in gastroenterology

authors： Pickhardt PJ

更新日期：2010-01-01 00:00:00

abstract：:The development of small bowel transplantation has long been hindered by the immunological and infectious barriers peculiar to the small bowel. Gradual progress has been achieved during the past decade with the use of tacrolimus and the availability of better anti-infection prophylaxis. The current status of small bow...

journal_title：Current opinion in gastroenterology

authors： Prasad KR,Pollard SG

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize publications on juvenile primary sclerosing cholangitis (PSC) published over the past 5 years. These studies contribute to the understanding of the clinical features, diagnostic pathways, genetic aspects, treatment and outcome of this condition. RECENT FINDINGS:Sclerosing cholangitis wit...

journal_title：Current opinion in gastroenterology

authors： Mieli-Vergani G,Vergani D

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The 'Final Rule,' issued by the Health Resources and Service Administration in 2000, mandated that liver allocation policy should be based on disease severity and probability of death, and - among other factors - should be independent of a candidate's residence or listing. As a result, the Organ Procu...

journal_title：Current opinion in gastroenterology

authors： Kalra A,Biggins SW

更新日期：2018-05-01 00:00:00

abstract：:Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural ...

journal_title：Current opinion in gastroenterology

authors： Nguyen NQ,Holloway RH

更新日期：2003-07-01 00:00:00