Abstract:
PURPOSE OF REVIEW:In this review article, we address emerging evidence for the medical and surgical treatment of the hospitalized patient with ulcerative colitis. RECENT FINDINGS:Ulcerative colitis is a chronic inflammatory disease involving the colon and rectum. About one-fifth of patients will be hospitalized from ulcerative colitis, and about 20-30%, experiencing an acute flare will undergo colectomy. Because of the significant clinical consequences, patients hospitalized need prompt evaluation for potential complications, stratification of disease severity, and a multidisciplinary team approach to therapy, which involves both the gastroenterologist and surgeon. Although corticosteroids remain first-line therapy, second-line medical rescue options, primarily infliximab or cyclosporine, are considered within 3-5 days of presentation. In conjunction, an early surgical consultation to present the possibility of a staged proctocolectomy as one of the therapeutic options is equally important. SUMMARY:A coordinated multidisciplinary, individualized approach to treatment, involving the patient preferences throughout the process, is optimal in providing patient-centered effective care.
journal_name
Curr Opin Gastroenteroljournal_title
Current opinion in gastroenterologyauthors
Levy LC,Coburn ES,Choi S,Holubar SDdoi
10.1097/MOG.0000000000000637subject
Has Abstractpub_date
2020-07-01 00:00:00pages
265-276issue
4eissn
0267-1379issn
1531-7056journal_volume
36pub_type
杂志文章abstract:PURPOSE OF REVIEW:Morbid obesity is an epidemic in the United States and parts of Europe, with severe health consequences. As the number of patients undergoing bariatric surgery has increased dramatically, it is crucial for the gastroenterologist caring for these patients to have a better understanding of the procedure...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3282f094b5
更新日期:2007-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Even though recent accumulated data can help to understand fundamental molecular mechanisms of progression of cholangiocarcinoma (CCA), its incidence and mortality still keep increasing worldwide with poor prognosis. As appropriate animal disease models are critical to fill the gap between the finding...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32835d6a3e
更新日期:2013-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Human colitis-associated cancers (CAC) represent a heterogeneous group of conditions in which multiple oncogenic pathways are involved. In this article, we review the latest studies using genetic, chemical, bacterial and innate immune-mediated experimental models of CAC. RECENT FINDINGS:Using the azo...
journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000281
更新日期:2016-07-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2017-11-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200001000-00003
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize publications on juvenile primary sclerosing cholangitis (PSC) published over the past 5 years. These studies contribute to the understanding of the clinical features, diagnostic pathways, genetic aspects, treatment and outcome of this condition. RECENT FINDINGS:Sclerosing cholangitis wit...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3283388f5b
更新日期:2010-05-01 00:00:00
abstract::Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200307000-00009
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200405000-00010
更新日期:2004-05-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000229
更新日期:2016-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:PURPOSE OF REVIEW:To provide a critical review of the literature concerning the significance of mucosal healing as a predictor of future clinical and endoscopic course in patients with inflammatory bowel disease. Particular focus is given to articles published within the last year. RECENT FINDINGS:In patients with Cro...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3283455c8f
更新日期:2011-07-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000181712.81657.0a
更新日期:2005-11-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000407
更新日期:2018-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000239873.06243.00
更新日期:2006-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e328353e61e
更新日期:2012-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Morbid obesity is associated with a high prevalence of psychopathological conditions that might have an impact on postsurgery outcomes. This review summarizes recent data about psychological disorders in obese patients before and after bariatric surgery as well as the assessment and impact of these fa...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e3283422482
更新日期:2011-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance. This review briefly summarizes advances in our understanding of the pathogenesis of nonalcoholic fatty liver disease and its prevalence, natural history and treatment....
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32801421a9
更新日期:2007-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32801424f3
更新日期:2007-03-01 00:00:00
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更新日期:2018-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200409000-00008
更新日期:2004-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000050
更新日期:2014-05-01 00:00:00
abstract::Complementary and alternative medicine (CAM) is becoming increasingly utilized as a form of health care, with recent studies suggesting that over 40% of Americans use some form of CAM. This has major financial implications for the health care industry. Traditional physicians frequently are unaware of CAM use by their ...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200003000-00016
更新日期:2000-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/01.mog.0000174223.74783.1b
更新日期:2005-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200205000-00013
更新日期:2002-05-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2008-09-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000611
更新日期:2020-03-01 00:00:00
abstract::Over the past several years, the pharmacologic treatment of obesity has undergone changes in safety, efficacy, and therapeutic targeting. The prevalence of cardiac valvulopathy associated with treatment with phentermine, fenfluramine, and dexfenfluramine is now becoming clarified with the publication of longer-term st...
journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
doi:10.1097/00001574-200203000-00011
更新日期:2002-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e328352b5ef
更新日期:2012-07-01 00:00:00