Abstract:
PURPOSE OF REVIEW:The aim of this article is to highlight literature published during the last year in the context of previous knowledge. RECENT FINDINGS:A number of novel techniques - high-resolution manometry, esophageal electrical impedance and intra-luminal ultrasound imaging - have improved our understanding of esophageal function in health and disease. Several studies address the function of longitudinal muscle layer of the esophagus in normal subjects and patients with motor disorders of the esophagus. Esophageal electrical impedance recordings reveal abnormal transit in patients with diffuse esophageal spasm, achalasia and patients with normal manometry. Loss of the mammalian Sprouty2 gene leads to enteric neuronal hyperplasia and esophageal achalasia. Several studies showed excellent long-term results of medical and surgical treatment of achalasia of the esophagus. For the first time, mechanisms of gastroesophageal reflux in critically ill mechanically ventilated patients are reported. Novel pharmacologic strategies in the treatment of reflux disease are highlighted. SUMMARY:Several novel techniques, perfected during recent years, have improved our understanding of esophageal function and dysfunction. A number of important observations, reviewed here, provide important insight into the pathogenesis of esophageal motor disorders and treatment of gastroesophageal reflux disease.
journal_name
Curr Opin Gastroenteroljournal_title
Current opinion in gastroenterologyauthors
Dogan I,Mittal RKdoi
10.1097/01.mog.0000231818.64138.8asubject
Has Abstractpub_date
2006-07-01 00:00:00pages
417-22issue
4eissn
0267-1379issn
1531-7056pii
00001574-200607000-00016journal_volume
22pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:To provide a critical review of the literature concerning the significance of mucosal healing as a predictor of future clinical and endoscopic course in patients with inflammatory bowel disease. Particular focus is given to articles published within the last year. RECENT FINDINGS:In patients with Cro...
journal_title:Current opinion in gastroenterology
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abstract:PURPOSE OF REVIEW:To summarize publications on juvenile primary sclerosing cholangitis (PSC) published over the past 5 years. These studies contribute to the understanding of the clinical features, diagnostic pathways, genetic aspects, treatment and outcome of this condition. RECENT FINDINGS:Sclerosing cholangitis wit...
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abstract:PURPOSE OF REVIEW:Human colitis-associated cancers (CAC) represent a heterogeneous group of conditions in which multiple oncogenic pathways are involved. In this article, we review the latest studies using genetic, chemical, bacterial and innate immune-mediated experimental models of CAC. RECENT FINDINGS:Using the azo...
journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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abstract:PURPOSE OF REVIEW:Radiologic imaging of the large intestine continues to evolve and expand the potential for noninvasive diagnosis. The aim of this review is to provide an update on current and emerging clinical capabilities for a variety of radiologic diagnostic imaging tools for evaluating the colon and rectum. RECE...
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0b013e32834ddab9
更新日期:2012-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
doi:10.1097/MOG.0000000000000021
更新日期:2014-01-01 00:00:00
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journal_title:Current opinion in gastroenterology
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更新日期:2010-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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更新日期:2011-05-01 00:00:00
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章,评审
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更新日期:2019-03-01 00:00:00
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
pub_type: 杂志文章
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journal_title:Current opinion in gastroenterology
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journal_title:Current opinion in gastroenterology
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更新日期:2014-11-01 00:00:00
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journal_title:Current opinion in gastroenterology
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pub_type: 杂志文章,收录出版
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journal_title:Current opinion in gastroenterology
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更新日期:2013-01-01 00:00:00