Role of autocrine and endocrine gastrin-like peptides in colonic carcinogenesis.

abstract：PURPOSE OF REVIEW:Radiologic imaging of the large intestine continues to evolve and expand the potential for noninvasive diagnosis. The aim of this review is to provide an update on current and emerging clinical capabilities for a variety of radiologic diagnostic imaging tools for evaluating the colon and rectum. RECE...

journal_title：Current opinion in gastroenterology

authors： Pickhardt PJ

更新日期：2010-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal is to review the most recent literature about biosimilars in inflammatory bowel disease (IBD), with emphasis on controversial regulatory issues. RECENT FINDINGS:Although biosimilars have been in use in Europe since 2005, the recent approval of CT-P13 (Remsima, Inflectra), a biosimilar of the...

journal_title：Current opinion in gastroenterology

authors： Gomollón F

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The 'precision medicine' refers to the generation of identification and classification criteria for advanced taxonomy of patients, exploiting advanced models to infer optimized clinical decisions for each disease phenotype. RECENT FINDINGS:The current article reviews new advances in the past 18 month...

journal_title：Current opinion in gastroenterology

authors： Putignani L,Gasbarrini A,Dallapiccola B

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a need for novel therapies for inflammatory bowel diseases (IBDs) that are well tolerated and effective. Currently, mesenchymal stem/stromal cells (MSCs) are being investigated in clinical trials for treatment of IBD. In this review, we update the recently published studies with an emphasis o...

journal_title：Current opinion in gastroenterology

authors： Dave M,Jaiswal P,Cominelli F

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This report reviews recent animal model and human studies associated with inflammatory responses in acute and chronic pancreatitis. RECENT FINDINGS:Animal model and limited human acute and chronic pancreatitis studies unravel the dynamic nature of the inflammatory processes and the ability of the imm...

journal_title：Current opinion in gastroenterology

authors： Habtezion A

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Small bowel capsule endoscopy (SBCE) was introduced 13 years ago by Given Imaging (Yokneam, Israel). It has become one of the most important investigational tools of the small bowel. The capsule is swallowed with water after a 12 h fast, propelled via peristalsis through the gastrointestinal tract and...

journal_title：Current opinion in gastroenterology

authors： Eliakim R

更新日期：2013-03-01 00:00:00

abstract：:The treatment of inflammatory bowel disease is a continually evolving area and a major focus of the current literature in gastroenterology. As further information is gained in the areas of etiology, pathophysiology, and natural history of the disease, new agents are developed, and management strategies are revised. Th...

journal_title：Current opinion in gastroenterology

authors： Nash CL,Sutherland LR

更新日期：2001-07-01 00:00:00

abstract：:The neurohormonal control of pancreatic exocrine secretion is a complex interaction of multiple pathways involving a large number of gut hormones, neurotransmitters, and neuropeptides. Recent studies have elucidated a role for cholecystokinin in the regulation of bicarbonate and fluid secretion from pancreatic duct ce...

journal_title：Current opinion in gastroenterology

authors： Nathan JD,Liddle RA

更新日期：2002-09-01 00:00:00

abstract：:The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...

journal_title：Current opinion in gastroenterology

authors： Logsdon CD

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In both Crohn's disease and ulcerative colitis, the tissue damage results from an inappropriate or exaggerated immune response to antigens of the gut microflora. This review summarizes current knowledge regarding the role of immune-inflammatory mediators in the pathogenesis of inflammatory bowel disea...

journal_title：Current opinion in gastroenterology

authors： Monteleone G,Fina D,Caruso R,Pallone F

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...

journal_title：Current opinion in gastroenterology

authors： Takakura WR,Tabibian JH,Bowlus CL

更新日期：2017-03-01 00:00:00

abstract：:Endoscopic management of biliary disease remains at the forefront of minimally invasive means of providing therapy, as well as contributing important diagnostic information in complex clinical scenarios. The authors review recent advances and reported trials of therapy and revisit important controversial issues. The m...

journal_title：Current opinion in gastroenterology

authors： Lew RJ,Kochman ML

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Endoscopic ampullectomy has proven its safety and efficacy in multiple studies, making it the favorable option for the management of endoscopic ampullectomy. In this review, we plan to review the basic steps every endoscopist should be familiar with before undertaking endoscopic ampullectomy. RECENT ...

journal_title：Current opinion in gastroenterology

authors： Klair JS,Irani S,Kozarek R

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Food addiction has been implicated as a putative causal factor in chronic overeating, binge eating, and obesity. The concept of food addiction has been controversial historically due to definitional and conceptual difficulties and to a lack of rigorous scientific data. RECENT FINDINGS:Support for the...

journal_title：Current opinion in gastroenterology

authors： Corsica JA,Pelchat ML

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Endoscopic approaches to obesity may help fulfill the unmet need of over half the US adult population who would benefit from therapy for obesity but are not receiving it. Endoluminal approaches have the potential to be more efficacious than antiobesity medications and have a lower risk-cost profile co...

journal_title：Current opinion in gastroenterology

authors： Kumbhari V,Oberbach A,Nimgaonkar A

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight the increasing evidence supporting the concept that microRNAs (miRNAs) are involved in the cause and pathogenesis of cholestatic liver disorders. RECENT FINDINGS:miRNAs play a key role in maintaining bile acid homeostasis and modulating pathological processes associated to liver cholesta...

journal_title：Current opinion in gastroenterology

authors： Marin JJ,Bujanda L,Banales JM

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonalcoholic fatty liver disease and its subset nonalcoholic steatohepatitis represent the liver manifestations of insulin resistance. This review briefly summarizes advances in our understanding of the pathogenesis of nonalcoholic fatty liver disease and its prevalence, natural history and treatment....

journal_title：Current opinion in gastroenterology

authors： Neuschwander-Tetri BA

更新日期：2007-03-01 00:00:00

abstract：:Intensive investigation into the interactions of Helicobacter pylori with the human host during the period of this review has led to several important developments in our understanding of H. pylori pathogenesis. There is direct evidence to support a central role for bacterial adhesion to host gastric epithelial Lewis ...

journal_title：Current opinion in gastroenterology

authors： Wilson KT,Fantry GT

更新日期：1999-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Knowledge on and understanding of the pathophysiology of inflammatory bowel disease (IBD) is continuously growing. Important insights from the last years are summarized in this review. RECENT FINDINGS:Further genetic risk factors for IBD have been identified and confirmed. Novel studies analyzing the...

journal_title：Current opinion in gastroenterology

authors： Scharl M,Rogler G

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The composition of activated adipose tissue with adipocytes secreting a broad spectrum of immune-modulatory adipokines next to adipose tissue-derived stromal cells and professional immune effector cells in the visceral fat creates a complex network of inflammatory processes shaping local immune respon...

journal_title：Current opinion in gastroenterology

authors： Paeschke A,Erben U,Kredel LI,Kühl AA,Siegmund B

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To examine recent advances in the techniques and technologies of endoscopic resection of early gastric cancer. RECENT FINDINGS:Endoscopic mucosal resection of early gastric cancer with no risk of lymph node metastasis has been a standard technique in Japan and is increasingly becoming accepted and re...

journal_title：Current opinion in gastroenterology

authors： Gotoda T

更新日期：2006-09-01 00:00:00

abstract：:Recently, much progress has been made in the field of tumor immunology. Much of this work has focused on understanding and exploiting the innate immune response to tumor cells. A novel human receptor-ligand system that mediates natural killer (NK) and gammadelta T-cell killing of carcinoma cells has been identified, a...

journal_title：Current opinion in gastroenterology

authors： Golby SJ,Spencer J

更新日期：2001-11-01 00:00:00

abstract：:This year's review has been divided into five sections: The first describes the natural history of drug-induced liver disease, the second discusses the issue of placebo-related increases in liver-associated enzymes, the third describes agents newly reported to cause hepatic injury, the fourth discusses new reports of ...

journal_title：Current opinion in gastroenterology

authors： Mayoral W,Lewis JH

更新日期：2000-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Jaundice, the physical finding associated with hyperbilirubinemia, results when the liver is unable to properly metabolize or excrete bilirubin. The purpose of this review is to examine some of the most common causes of jaundice in adults, provide insight into the diagnostic evaluation of jaundice, an...

journal_title：Current opinion in gastroenterology

authors： Sullivan JI,Rockey DC

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF THIS REVIEW:In the last 2 years, several studies have been published that will change the management of patients with Barrett's esophagus. In this review, we will discuss the most relevant studies as well as future prospects in this field. RECENT FINDINGS:Long-term follow-up studies have shown that to be co...

journal_title：Current opinion in gastroenterology

authors： Bergman JJ

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the advances in diagnostic modalities and management options for defecatory dysfunction and highlight the areas in need of further research. RECENT FINDINGS:The diagnostic utility of high-resolution anorectal manometry (ARM), which has emerged as a promising tool for the diagnosis of def...

journal_title：Current opinion in gastroenterology

authors： Neshatian L

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The molecular biology revolution has led to a significant improvement in our understanding of biological and physiological processes. Such expansion of knowledge has also covered the field of intestinal absorption of water-soluble vitamins and is the subject of this review. RECENT FINDINGS:Impressive...

journal_title：Current opinion in gastroenterology

authors： Said HM,Mohammed ZM

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Catheter-related bloodstream infections (CRBSIs) account for a major source of morbidity in children with intestinal failure. Many of these patients require long-term central venous access, placing them at significant risk for these infections. The purpose of this review is to highlight the most curre...

journal_title：Current opinion in gastroenterology

authors： Piper HG,Wales PW

更新日期：2013-01-01 00:00:00

abstract：:Gastric adenocarcinoma is the most common malignancy of the upper gastrointestinal tract. During the past two decades it has migrated toward the gastroesophageal junction. Gastroesophageal reflux and obesity may play a role. Recent research suggests that a number of biologic and molecular differences exist in patients...

journal_title：Current opinion in gastroenterology

authors： Yao JC,Ajani JA

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Morbid obesity is an epidemic in the United States and parts of Europe, with severe health consequences. As the number of patients undergoing bariatric surgery has increased dramatically, it is crucial for the gastroenterologist caring for these patients to have a better understanding of the procedure...

journal_title：Current opinion in gastroenterology

authors： Lee CW,Kelly JJ,Wassef WY

更新日期：2007-11-01 00:00:00