To resect or not to resect: a review of pancreatic cyst disease management.

Abstract:

PURPOSE OF REVIEW:With recent advances in radiographic testing, there have been increases in the incidental identification of pancreatic cysts. Determining management, specifically, which cysts can be watched versus intervened upon has significant impact on at the patient-physician level as well as globally on resource allocation and healthcare expenditures. This review focuses on the three main guidelines (Fukuoka guidelines, European consensus, and American Gastroenterological Association recommendations) for management of pancreatic cystic disease after incidental identification. RECENT FINDINGS:There are iterant revisions to each set of recommendations every few years as new data is published on the subject. This review encompasses the most up-to-date recommendations for management while also providing a framework for conceptualizing work-up for varying types of pancreatic cystic disease before and after incidental identification. SUMMARY:Pancreatic cystic disease should be approached in thoughtful clinical manner, and each cyst should be evaluated in the context of patient's health and healthcare goals. All cysts, however, should be considered malignant until proven otherwise. Applications of different diagnostic modalities like MRI and EUS with FNA can better characterize cystic lesions and assess malignant potential. Resection should always be considered in cysts with concerning features. If deferred, surveillance should be continued indefinitely. Early termination of surveillance risks future malignant progression.

authors

Harrison JM,Castillo CF

doi

10.1097/MOG.0000000000000463

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

343-348

issue

5

eissn

0267-1379

issn

1531-7056

journal_volume

34

pub_type

杂志文章,评审
  • Endoscopic management of biliary disease.

    abstract::Endoscopic management of biliary disease remains at the forefront of minimally invasive means of providing therapy, as well as contributing important diagnostic information in complex clinical scenarios. The authors review recent advances and reported trials of therapy and revisit important controversial issues. The m...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200009000-00012

    authors: Lew RJ,Kochman ML

    更新日期:2000-09-01 00:00:00

  • The assessment and management of defecatory dysfunction: a critical appraisal.

    abstract:PURPOSE OF REVIEW:To summarize the advances in diagnostic modalities and management options for defecatory dysfunction and highlight the areas in need of further research. RECENT FINDINGS:The diagnostic utility of high-resolution anorectal manometry (ARM), which has emerged as a promising tool for the diagnosis of def...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000407

    authors: Neshatian L

    更新日期:2018-01-01 00:00:00

  • Metals and the liver.

    abstract:PURPOSE OF REVIEW:Hereditary liver diseases resulting in copper and iron overload may cause significant morbidity and mortality if not diagnosed and treated early. The goal of this review is to highlight the key publications on genetics, diagnosis and management of hemochromatosis and Wilson disease over the past 18 mo...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e3283521d82

    authors: Maxwell KL,Kowdley KV

    更新日期:2012-05-01 00:00:00

  • Endoscopic management of bariatric surgical complications.

    abstract:PURPOSE OF REVIEW:Bariatric surgery is recognized as the most effective treatment against obesity as it results in significant weight reduction and a high rate of remission of obesity-related comorbidities. However, bariatric surgery is not uncommonly associated with complications and an endoscopic approach to manageme...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000202

    authors: Kumbhari V,Cai JX,Schweitzer MA

    更新日期:2015-09-01 00:00:00

  • Role of autocrine and endocrine gastrin-like peptides in colonic carcinogenesis.

    abstract::Colon carcinogenesis is a multistep process that involves deletions, mutations, and changes in expression of genes that regulate growth, differentiation, and apoptosis. Hyperproliferation can initiate dysplastic growth, resulting in accumulation of genetic defects and progression of colon cancer. Although genetic inst...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200001000-00013

    authors: Singh P,Dai B,Wu H,Owlia A

    更新日期:2000-01-01 00:00:00

  • Steroids versus dietary therapy for the treatment of eosinophilic esophagitis.

    abstract:PURPOSE OF REVIEW:Eosinophilic esophagitis (EoE) is a condition characterized by dense mucosal eosinophilia in conjunction with symptoms of esophageal dysfunction. Since both the incidence and prevalence of EoE are on the rise in both children and adults, understanding the various treatment options available is imperat...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000086

    authors: Gonsalves N

    更新日期:2014-07-01 00:00:00

  • Clinical nutrition for the gastroenterologist: the physiologic rationale for providing early nutritional therapy to the hospitalized patient.

    abstract:PURPOSE OF REVIEW:Conflicting reports in the literature have been misinterpreted by clinicians, who conclude that nutritional therapy for the hospitalized patient is of marginal value. The true benefit of such therapy is derived from the provision of early enteral nutrition. This article describes the physiologic respo...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000618

    authors: McClave SA,Omer E

    更新日期:2020-03-01 00:00:00

  • Pancreatic surgery for adenocarcinoma.

    abstract:PURPOSE OF REVIEW:Pancreatic resection remains among the most formidable and complex of abdominal surgical operations. Nonetheless, recent observations have continued to provide incremental improvement in both our evidence for treatment regimens and the technology, resulting in better outcomes. RECENT FINDINGS:Neoadju...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e3283567f2c

    authors: Warshaw AL,Lillemoe KD,Fernandez-del Castillo C

    更新日期:2012-09-01 00:00:00

  • Utility of the Citrobacter rodentium infection model in laboratory mice.

    abstract:PURPOSE OF REVIEW:There have been considerable advances in our understanding of the molecular pathogenesis of enteropathogenic Escherichia coli and enterohemorrhagic E. coli infection. Given the difficulty of infecting laboratory mice with these diarrhea-causing pathogens, a growing number of studies have found the mur...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/MOG.0b013e3282f2b0fb

    authors: Borenshtein D,McBee ME,Schauer DB

    更新日期:2008-01-01 00:00:00

  • Biliary endoscopy.

    abstract::Highlighting this year was the National Institutes of Health (NIH) State-of-the-Science Conference on endoscopic retrograde cholangiopancreatography. The panel addressed controversies in biliary endoscopy and set the framework for future funding for clinical research endeavors. With respect to biliary endoscopy, the l...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200305000-00013

    authors: Beilstein MC,Kochman ML

    更新日期:2003-05-01 00:00:00

  • Primary endoscopic therapies for obesity and metabolic diseases.

    abstract:PURPOSE OF REVIEW:Endoscopic approaches to obesity may help fulfill the unmet need of over half the US adult population who would benefit from therapy for obesity but are not receiving it. Endoluminal approaches have the potential to be more efficacious than antiobesity medications and have a lower risk-cost profile co...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000203

    authors: Kumbhari V,Oberbach A,Nimgaonkar A

    更新日期:2015-09-01 00:00:00

  • Diagnosis and evaluation of hyperbilirubinemia.

    abstract:PURPOSE OF REVIEW:Jaundice, the physical finding associated with hyperbilirubinemia, results when the liver is unable to properly metabolize or excrete bilirubin. The purpose of this review is to examine some of the most common causes of jaundice in adults, provide insight into the diagnostic evaluation of jaundice, an...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000354

    authors: Sullivan JI,Rockey DC

    更新日期:2017-05-01 00:00:00

  • Cryotherapy for Barrett's esophagus and esophageal cancer.

    abstract:PURPOSE OF REVIEW:To summarize the recent literature on endoscopic spray cryotherapy for the treatment of Barrett's esophagus and esophageal cancer. RECENT FINDINGS:Endoscopic spray cryotherapy is a relatively new ablative modality for the treatment of gastrointestinal diseases. Spray cryotherapy rapidly cools tissues...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e328347bae8

    authors: Greenwald BD,Dumot JA

    更新日期:2011-07-01 00:00:00

  • Obesity pharmacology: past, present, and future.

    abstract::Over the past several years, the pharmacologic treatment of obesity has undergone changes in safety, efficacy, and therapeutic targeting. The prevalence of cardiac valvulopathy associated with treatment with phentermine, fenfluramine, and dexfenfluramine is now becoming clarified with the publication of longer-term st...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200203000-00011

    authors: Kushner RF,Manzano H

    更新日期:2002-03-01 00:00:00

  • Pathogenesis of inflammatory bowel disease.

    abstract::In spite of expanding knowledge of cellular and molecular mechanisms of intestinal inflammation, the etiology and pathogenesis of inflammatory bowel disease (IBD) remain obscure. The link between the environment and IBD is still circumstantial, but definite progress is occurring in defining genetic susceptibility loci...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-199907000-00003

    authors: Katz JA,Itoh J,Fiocchi C

    更新日期:1999-07-01 00:00:00

  • Iron deficiency anemia: diagnosis and management.

    abstract:PURPOSE OF REVIEW:Iron deficiency anemia (IDA) still remains universally problematic worldwide. The primary focus of this review is to critique articles published over the past 18 months that describe strategies for the diagnosis and management of this prevalent condition. RECENT FINDINGS:The medical community continu...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e32831ef1cd

    authors: Clark SF

    更新日期:2009-03-01 00:00:00

  • Pouchitis: lessons for inflammatory bowel disease.

    abstract:PURPOSE OF REVIEW:One of the significant limitations to the investigation of inflammatory bowel disease (IBD) in humans is the impossibility of studying this condition from the beginning of the disease process to understand the individual contribution of the various microbiological and immunological components to its p...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e32832b36eb

    authors: Wu H,Shen B

    更新日期:2009-07-01 00:00:00

  • Biliary tract cancer.

    abstract::Advances in cellular and molecular biology of extrahepatic cholangiocarcinoma and gallbladder adenocarcinoma are providing innovative means for the diagnosis and treatment of biliary tract cancer. Similarly, refinements in noninvasive studies--including helical computed tomography, magnetic resonance cholangiopancreat...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200109000-00009

    authors: Abdalla EK,Vauthey JN

    更新日期:2001-09-01 00:00:00

  • Inherited metabolic disease.

    abstract::The elucidation of metabolic pathways and the genetic basis for diseases of the liver continues to increase our understanding of disease pathogenesis and advance treatment options. This selective review covers a wide range of subjects, from the identification of novel proteins and the importance of specific transport ...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200205000-00003

    authors: Schilsky ML

    更新日期:2002-05-01 00:00:00

  • Chronic pancreatitis.

    abstract::In the past year, numerous important papers were published on chronic pancreatitis, its causes, and its diagnosis; the cause of fibrosis; and pain in pancreatic cancer. More than 750 mutations have been described in the cystic fibrosis transmembrane regulator (CFTR) gene. Some mutations cause relatively mild reduction...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-199909000-00005

    authors: Chari ST,Dimagno EP

    更新日期:1999-09-01 00:00:00

  • Role of innate immunity in cancer.

    abstract::Recently, much progress has been made in the field of tumor immunology. Much of this work has focused on understanding and exploiting the innate immune response to tumor cells. A novel human receptor-ligand system that mediates natural killer (NK) and gammadelta T-cell killing of carcinoma cells has been identified, a...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200111000-00015

    authors: Golby SJ,Spencer J

    更新日期:2001-11-01 00:00:00

  • New clinical paradigms for treating and preventing antiplatelet gastrointestinal bleeding.

    abstract:PURPOSE OF REVIEW:To quantify antiplatelet-related gastrointestinal bleeding (GIB), characterize patients at greatest risk and summarize risk-management strategies emphasizing evolving knowledge in acute management of antiplatelet-related bleeding. RECENT FINDINGS:New paradigms for acute management of antiplatelet-rel...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000394

    authors: Abraham NS

    更新日期:2017-11-01 00:00:00

  • How soon should we start interventional feeding in the ICU?

    abstract:PURPOSE OF REVIEW:Nutrition in the critically ill patient remains a controversial topic. Most clinicians have viewed nutrition as part of patient care but not as a therapeutic intervention. Recent studies have looked at type and timing of nutrition to determine whether they affect important clinical outcomes. RECENT F...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000047

    authors: Fremont RD,Rice TW

    更新日期:2014-03-01 00:00:00

  • Pathogenesis of Helicobacter pylori infection.

    abstract::Intensive investigation into the interactions of Helicobacter pylori with the human host during the period of this review has led to several important developments in our understanding of H. pylori pathogenesis. There is direct evidence to support a central role for bacterial adhesion to host gastric epithelial Lewis ...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-199901000-00012

    authors: Wilson KT,Fantry GT

    更新日期:1999-01-01 00:00:00

  • Inflammatory bowel disease pathogenesis: what is new?

    abstract:PURPOSE OF REVIEW:Knowledge on and understanding of the pathophysiology of inflammatory bowel disease (IBD) is continuously growing. Important insights from the last years are summarized in this review. RECENT FINDINGS:Further genetic risk factors for IBD have been identified and confirmed. Novel studies analyzing the...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e328353e61e

    authors: Scharl M,Rogler G

    更新日期:2012-07-01 00:00:00

  • Portal hypertension.

    abstract:PURPOSE OF REVIEW:Significant advances in the pathophysiology, diagnosis and management of the complications of portal hypertension that have occurred in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to experimental studies aimed at modifying the factors that lead to port...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mog.0000218962.93806.9a

    authors: Garcia-Tsao G

    更新日期:2006-05-01 00:00:00

  • Signal transduction in pancreatic acinar cell physiology and pathophysiology.

    abstract::The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章

    doi:10.1097/00001574-200009000-00002

    authors: Logsdon CD

    更新日期:2000-09-01 00:00:00

  • Acute nonvariceal upper gastrointestinal bleeding.

    abstract:PURPOSE OF REVIEW:To review recent literature (2009-2010) on acute nonvariceal upper gastrointestinal hemorrhage. RECENT FINDINGS:There is a decreasing trend in the incidence and hospitalization for acute nonvariceal upper gastrointestinal hemorrhage worldwide, with significant improvement in rebleeding and mortality....

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e32833d1746

    authors: Chiu PW,Sung JJ

    更新日期:2010-09-01 00:00:00

  • Does everyone with inflammatory bowel disease need to be treated with combination therapy?

    abstract:PURPOSE OF REVIEW:This article describes the evolution of combination therapy in inflammatory bowel disease and how to determine when combination may not be necessary. RECENT FINDINGS:The combination of an immunosuppressive agent with an antibody to tumor necrosis factor has proven to be more effective than monotherap...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0000000000000281

    authors: Bernstein CN

    更新日期:2016-07-01 00:00:00

  • Detection and endoscopic therapy of early esophageal adenocarcinoma.

    abstract:PURPOSE OF REVIEW:This review summarizes recent progress on endoscopic diagnosis and treatment of esophageal high-grade intraepithelial neoplasia and early adenocarcinoma and critically analyzes the literature in the context of preexisting scientific data. RECENT FINDINGS:Narrow band imaging and computed virtual chrom...

    journal_title:Current opinion in gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1097/MOG.0b013e3282ff8b1f

    authors: Seewald S,Ang TL,Groth S,Zhong Y,Bertschinger P,Altorfer J,Thonke F,Soehendra N

    更新日期:2008-07-01 00:00:00