Chest pain of esophageal origin.

abstract：PURPOSE OF REVIEW:Autoimmune hepatitis (AIH) is a chronic disease characterized by a lymphocyte infiltrate in the liver. For decades, nonspecific immunosuppression has been used to limit chronic liver inflammation. The high risk of relapse, the treatments side effects, and the significant number of refractory patients ...

journal_title：Current opinion in gastroenterology

authors： Cardon A,Conchon S,Renand A

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Eosinophilic colitis is a rare condition, with a prevalence rate in the USA of 2-3/100 000 persons (0.003%), but diagnosed in 0.1% of biopsies in those colonoscoped for diarrhoea. Secondary colonic eosinophilia is more common and associated with systemic, colonic and infectious diseases. In this revie...

journal_title：Current opinion in gastroenterology

authors： Walker MM,Potter MD,Talley NJ

更新日期：2019-01-01 00:00:00

abstract：:Highlighting this year was the National Institutes of Health (NIH) State-of-the-Science Conference on endoscopic retrograde cholangiopancreatography. The panel addressed controversies in biliary endoscopy and set the framework for future funding for clinical research endeavors. With respect to biliary endoscopy, the l...

journal_title：Current opinion in gastroenterology

authors： Beilstein MC,Kochman ML

更新日期：2003-05-01 00:00:00

abstract：:Endoscopic management of biliary disease remains at the forefront of minimally invasive means of providing therapy, as well as contributing important diagnostic information in complex clinical scenarios. The authors review recent advances and reported trials of therapy and revisit important controversial issues. The m...

journal_title：Current opinion in gastroenterology

authors： Lew RJ,Kochman ML

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will summarize the most significant work that contributed to the understanding of liver fibrosis progression and resolution, which in turn has yielded new areas of therapeutic targeting. RECENT FINDINGS:Liver fibrosis is the result of an imbalance between production and dissolution of ext...

journal_title：Current opinion in gastroenterology

authors： Jiao J,Friedman SL,Aloman C

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize recent advances in defining the clinical features, pathophysiology, natural history, and treatment of nonalcoholic fatty liver disease. RECENT FINDINGS:Nonalcoholic fatty liver disease is present in approximately 30% of the US population. A histologic gradin...

journal_title：Current opinion in gastroenterology

authors： Greenfield V,Cheung O,Sanyal AJ

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary sclerosing cholangitis (PSC) is a rare, idiopathic biliary disease often with an insidious onset, variable disease course, and premature death related to benign and malignant PSC-related sequelae. This review aims to discuss the epidemiology, clinical variants, and natural history of PSC, inco...

journal_title：Current opinion in gastroenterology

authors： Takakura WR,Tabibian JH,Bowlus CL

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Availability of direct acting antivirals (DAAs) that demonstrate remarkable clinical efficacy and safety has revolutionized the ability to treat chronic infection with hepatitis C virus (HCV). An equal measure of clinical success has now been achieved in persons coinfected with HCV and the HIV, a hist...

journal_title：Current opinion in gastroenterology

authors： Meissner EG

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Noroviruses (NoVs) are the most common cause of epidemic and sporadic cases of acute gastroenteritis worldwide. This review summarizes recent NoV disease burden estimates, epidemiology findings and provides an update on virus-like particle (VLP) vaccine studies. RECENT FINDINGS:NoVs are the leading c...

journal_title：Current opinion in gastroenterology

authors： Ramani S,Atmar RL,Estes MK

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Fermentable oligosaccharides disaccharides monosaccharides and polyols (FODMAP) dietary restriction ameliorates irritable bowel syndrome (IBS) symptoms; however, not all individuals with IBS respond. Given the gut microbiome's role in carbohydrate fermentation, investigators have evaluated whether the...

journal_title：Current opinion in gastroenterology

authors： Chumpitazi BP

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Nutrition in the critically ill patient remains a controversial topic. Most clinicians have viewed nutrition as part of patient care but not as a therapeutic intervention. Recent studies have looked at type and timing of nutrition to determine whether they affect important clinical outcomes. RECENT F...

journal_title：Current opinion in gastroenterology

authors： Fremont RD,Rice TW

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update of the advantages of new-generation molecular diagnostics as regards acute diarrhea, and to evaluate how they can help clinicians and researchers diagnose this condition. RECENT FINDINGS:Thanks to real-time polymerase chain reaction techniques, many enteropathogens can now be ide...

journal_title：Current opinion in gastroenterology

authors： Guarino A,Giannattasio A

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review evidence relating to the strength of associations that have appeared in largely observational studies, between high-dose or long-term use of proton pump inhibitor drugs and certain possibly attributable side-effects, which emerge from studies confounded by other variables. In retrospective s...

journal_title：Current opinion in gastroenterology

authors： McCarthy DM

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Morbid obesity is associated with a high prevalence of psychopathological conditions that might have an impact on postsurgery outcomes. This review summarizes recent data about psychological disorders in obese patients before and after bariatric surgery as well as the assessment and impact of these fa...

journal_title：Current opinion in gastroenterology

authors： Pataky Z,Carrard I,Golay A

更新日期：2011-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The workup of chronic unexplained diarrhea can be equally frustrating for care providers and patients. It carries a physical, financial, and social toll. In this review we provide a sensible approach to evaluating and managing chronic diarrhea. RECENT FINDINGS:Bile acid diarrhea is becoming increasin...

journal_title：Current opinion in gastroenterology

authors： Dosanjh G,Pardi DS

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapy for inflammatory bowel diseases (IBD) has changed dramatically in recent years with a wider use of immunomodulators and the introduction of antitumor necrosis factor (anti-TNF) agents. This article reviews the existing data on the long-term efficacy of biologics, that is, anti-TNF agents, for ...

journal_title：Current opinion in gastroenterology

authors： Sokol H,Seksik P,Cosnes J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Pancreatic resection remains among the most formidable and complex of abdominal surgical operations. Nonetheless, recent observations have continued to provide incremental improvement in both our evidence for treatment regimens and the technology, resulting in better outcomes. RECENT FINDINGS:Neoadju...

journal_title：Current opinion in gastroenterology

authors： Warshaw AL,Lillemoe KD,Fernandez-del Castillo C

更新日期：2012-09-01 00:00:00

abstract：:Toxic effects in the upper gastrointestinal tract, primarily complicated gastric and intestinal ulcers, are the most common undesirable effects of the nonsteroidal anti-inflammatory drugs. During the last several years, there have been several advances, both in the laboratory and clinically, toward reducing nonsteroid...

journal_title：Current opinion in gastroenterology

authors： Cryer B

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Inflammatory bowel disease commonly affects women during the childbearing years, and young couples are often concerned about the potential effects of inflammatory bowel disease on fertility, pregnancy, and the fetus. This review will critically consider advances over the past 2 years in our knowledge ...

journal_title：Current opinion in gastroenterology

authors： Katz JA

更新日期：2004-07-01 00:00:00

abstract：:Recently, much progress has been made in the field of tumor immunology. Much of this work has focused on understanding and exploiting the innate immune response to tumor cells. A novel human receptor-ligand system that mediates natural killer (NK) and gammadelta T-cell killing of carcinoma cells has been identified, a...

journal_title：Current opinion in gastroenterology

authors： Golby SJ,Spencer J

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Increasing antimicrobial resistance in Salmonella Typhi is a serious public health concern, especially in industrializing countries. Here we review recent clinical and laboratory data concerning the evolution of antimicrobial resistance, with particular reference to the emergence resistance against fl...

journal_title：Current opinion in gastroenterology

authors： Karkey A,Thwaites GE,Baker S

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article highlights recent advances in viral hepatitis published from December 2003 to November 2004. Studies reporting novel and clinically relevant findings were selected after a PubMed search. The aim is to provide an up-to-date summary of important developments in viral hepatitis. RECENT FIND...

journal_title：Current opinion in gastroenterology

authors： Fung SK,Lok AS

更新日期：2005-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Hereditary liver diseases resulting in copper and iron overload may cause significant morbidity and mortality if not diagnosed and treated early. The goal of this review is to highlight the key publications on genetics, diagnosis and management of hemochromatosis and Wilson disease over the past 18 mo...

journal_title：Current opinion in gastroenterology

authors： Maxwell KL,Kowdley KV

更新日期：2012-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Submucosal endoscopy with mucosal flap (SEMF), a new diagnostic and therapeutic intervention of flexible endoscopy, has been examined from the perspective of developmental laboratory work, procedural details, and results of early clinical experiences. RECENT FINDINGS:Diagnostic natural orifice transl...

journal_title：Current opinion in gastroenterology

authors： Sumiyama K,Gostout CJ

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The composition of activated adipose tissue with adipocytes secreting a broad spectrum of immune-modulatory adipokines next to adipose tissue-derived stromal cells and professional immune effector cells in the visceral fat creates a complex network of inflammatory processes shaping local immune respon...

journal_title：Current opinion in gastroenterology

authors： Paeschke A,Erben U,Kredel LI,Kühl AA,Siegmund B

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent literature (2009-2010) on acute nonvariceal upper gastrointestinal hemorrhage. RECENT FINDINGS:There is a decreasing trend in the incidence and hospitalization for acute nonvariceal upper gastrointestinal hemorrhage worldwide, with significant improvement in rebleeding and mortality....

journal_title：Current opinion in gastroenterology

authors： Chiu PW,Sung JJ

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This focused, narrative review summarizes human clinical trial data for direct-acting antimicrobials in development for the treatment of gastrointestinal infections that were published in the past 18 months (1 January 2019 to 30 June 2020). RECENT FINDINGS:Antimicrobial agents for Clostridioides diff...

journal_title：Current opinion in gastroenterology

authors： Carlson TJ,Gonzales-Luna AJ,Garey KW

更新日期：2021-01-01 00:00:00

abstract：:The pancreatic acinar cell is a valuable cell model for understanding how activation of plasma membrane receptors generates signals that propagate, amplify, diversify, and integrate to control cellular function. A primary signaling system involves the activation of heterotrimeric G proteins that stimulate phospholipas...

journal_title：Current opinion in gastroenterology

authors： Logsdon CD

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To consider observations suggesting that the bacterial protein flagellin, the primary structural component of flagella, plays a major role in mediating gut inflammation associated with infection by enteric pathogens and in inflammatory bowel disease. RECENT FINDINGS:Biochemical dissection of an in-vi...

journal_title：Current opinion in gastroenterology

authors： Gewirtz AT

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The 2009 review on small intestinal ion transport, in this series, focused on recent advances in duodenal bicarbonate secretion, the importance of scaffolding proteins and the pathophysiology of inflammation-associated diarrhea. The current review focuses on advances in ion-coupled solute transport, t...

journal_title：Current opinion in gastroenterology

authors： Venkatasubramanian J,Ao M,Rao MC

更新日期：2010-03-01 00:00:00