Nutritional copper deficiency does not affect sponge granuloma formation in the rat.

Abstract:

:Sponge granuloma formation was compared in copper-deficient and copper-sufficient rats following feeding of respective diets for 20, 40, or 60 d. Body weight, total blood hemoglobin, and activities of ceruloplasmin and Cu, Zn-superoxide dismutase in plasma were monitored to ascertain copper deficiency. Mean granuloma weights (mg +/- SEM) in copper-deficient and copper-sufficient groups of rats, respectively, were as follows: 37 +/- 2 and 38 +/- 2 after 20 d, 22 +/- 2 and 23 +/- 2 after 40 d, and 19 +/- 1 and 21 +/- 1 after 60 d on respective diets. Thus, nutritional copper deficiency did not have an effect on sponge granuloma formation in the rat.

journal_name

Biol Trace Elem Res

authors

Kishore V,Boutte V,Fourcade L

doi

10.1007/BF02990272

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

115-22

issue

2

eissn

0163-4984

issn

1559-0720

journal_volume

25

pub_type

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