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Serotonin inhibition and sleep.

Abstract：

:Methysergide a clinically used blocker of serotonin receptors, was given for 48 hr to 11 normal adults, at a dose of 8 mg per 24 hr. Total REM sleep time was decreased, although total sleep time was unchanged. Stage 4 decreased and stage 3 increased, while total slow wave sleep remained constant. There was a tendency toward a decrease in the number of intact sleep cycles. The relationship of these data to published reports on p-chlorophenylalanine is discussed.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Mendelson WB,Reichman J,Othmer E

subject

Has Abstract

pub_date

1975-08-01 00:00:00

pages

459-64

issue

4

eissn

0006-3223

issn

1873-2402

journal_volume

10

pub_type

临床试验,杂志文章

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