Role of fatty acids in the transition from anaerobic to aerobic metabolism in skeletal muscle during exercise.

abstract：:Cardiac hypertrophy is characterized by remodeling of the extracellular matrix (ECM). Integrins are cell-surface molecules that link the ECM to the cellular cytoskeleton where they play roles as signaling molecules and transducers of mechanical force. To clarify the possible roles of integrins in cardiac myocyte hyper...

journal_title：Cell biochemistry and function

authors： Kim DJ,Park SH,Lim CS,Chun JS,Kim JK,Song WK

更新日期：2003-03-01 00:00:00

abstract：:The aim of the present study is to evaluate the proliferation- and migration-enhancing effects of ginseng and its component, ginsenoside (Rg1) on RSC96 Schwann cells. We investigated the molecular signaling pathways, which include: (1) survival signaling, IGFs-IGFIR-Akt-Bcl2 and proliferative signaling, cell cycle fac...

journal_title：Cell biochemistry and function

authors： Lu MC,Lai TY,Hwang JM,Chen HT,Chang SH,Tsai FJ,Wang HL,Lin CC,Kuo WW,Huang CY

更新日期：2009-06-01 00:00:00

abstract：:Glioma is one of the most common brain tumors and one of the most aggressive cancers. Although extensive progress has been made regarding to the diagnosis and treatment, the mortality in glioma patients is still high. Therefore, finding new therapeutic targets to the glioma is critical to the advancement in cancer tre...

journal_title：Cell biochemistry and function

authors： Wu H,Li J,Xu D,Jv D,Meng X,Qiao P,Cui T,Shi B

更新日期：2016-10-01 00:00:00

abstract：:The subcellular distribution of newly absorbed iron in isolated mouse duodenal enterocytes was investigated by analytical subcellular fractionation using sucrose density gradient centifugation. Two major peaks of mucosal 59Fe activity were observed: one soluble and one particulate (density 1.18-1.20 g ml-1). The latte...

journal_title：Cell biochemistry and function

authors： Snape S,Simpson RJ,Peters TJ

更新日期：1990-04-01 00:00:00

abstract：:Diabetes is associated with increased reactivity of the renal vascular bed to endothelin-1 (ET-1). It has been observed that diabetes is associated with over-expression of ET(A)- and ET(B)-receptors in the rat renal cortex. However it is not known if these receptors are over-expressed in the renal artery. The objectiv...

journal_title：Cell biochemistry and function

authors： Yousif MH

更新日期：2006-09-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is the most common renal tumour in adults. Altered levels of secondary messengers, that is, intracellular calcium and cyclic AMP (cAMP), have been implicated in the pathogenesis of various malignancies. In the present study, we measured levels of intracellular calcium and cAMP in RCC. The in...

journal_title：Cell biochemistry and function

authors： Sharma U,Singh SK,Rajendra P

更新日期：2012-12-01 00:00:00

abstract：:Bone tumor incidence in women peaks at age 50-60, coinciding with the menopause. That estrogen (E2) and triiodothyronine (T3) interact in bone metabolism has been well established. However, few data on the action of these hormones are available. Our purpose was to determine the role of E2 and T3 in the expression of b...

journal_title：Cell biochemistry and function

authors： Saraiva PP,Teixeira SS,Conde SJ,Nogueira CR

更新日期：2008-01-01 00:00:00

abstract：:The activity and hormonal regulation of NAD- and NADP-linked isocitrate dehydrogenase (EC.1.1.1.41 and EC.1.1.1.42, respectively) in the brain, liver and kidney cortex of female rats of various ages was investigated. The activity of NAD-ICDH of brain was greater than extramitochondrial (-c) or intramitochondrial (-m) ...

journal_title：Cell biochemistry and function

authors： Yadav RN

更新日期：1988-07-01 00:00:00

abstract：:Cyclophilin A (Cyp A), a member of the peptidyl-prolyl isomerase (PPI) family, may function as a molecular signalling switch. Comparative proteomic studies have identified Cyp A as a potential downstream target of protein kinase B (Akt). This study confirmed that Cyp A is a downstream effector of the phosphatidylinosi...

journal_title：Cell biochemistry and function

authors： Lin ZL,Wu HJ,Chen JA,Lin KC,Hsu JH

更新日期：2015-12-01 00:00:00

abstract：:Mast cells are widely distributed in the body and affect their surrounding environment through degranulation and secretion of cytokines. Conversely, mast cells are influenced by environmental stimuli such as cyclical mechanical stretch (CMS), such as that induced by heartbeat and respiration. Peripherally distributed ...

journal_title：Cell biochemistry and function

authors： Komiyama H,Miyake K,Asai K,Mizuno K,Shimada T

更新日期：2014-01-01 00:00:00

abstract：:To determine the temporal roles of phosphatidylinositol 3-kinase (PI3-kinase) and phospholipase D (PLD) during human neutrophil activation stimulated by a chemotactic peptide, we examined the kinetics of these enzymes and related them to a neutrophil function (superoxide production). Both wortmannin and 2-(4-morpholin...

journal_title：Cell biochemistry and function

authors： Yasui K,Komiyama A

更新日期：2001-03-01 00:00:00

abstract：:Sprouty1 protein belongs to a family of receptor tyrosine kinase-mediated signaling inhibitors, whose members are usually regulated by growth factors to form a negative feedback loop. Correspondingly fluctuations of Sprouty1 mRNA in response to single growth factors have been observed. In this report, we investigate S...

journal_title：Cell biochemistry and function

authors： Kral RM,Mayer CE,Vanas V,Gsur A,Sutterlüty-Fall H

更新日期：2014-01-01 00:00:00

abstract：:Beta-glucosidase activity was evaluated in situ by means of fluorogenic probes in normal human fibroblasts and fibroblasts from homozygous carriers of the Gaucher trait. Probe internalization, targeting to lysosomes and post-cleavage probe retention were the primary concerns. Internalization and targeting were attempt...

journal_title：Cell biochemistry and function

authors： Kohen E,Kohen C,Hirschberg JG,Santus R,Grabowski G,Mangel W,Gatt S,Prince J

更新日期：1993-09-01 00:00:00

abstract：:Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by selective destruction of insulin secreting pancreatic islets beta-cells. The formation of cytokines (IL-1beta, IL-6, TNF-alpha, etc.) leads to extensive morphological damage of beta-cells, DNA fragmentation, decrease of glucos...

journal_title：Cell biochemistry and function

authors： Briede J,Stivrina M,Stoldere Dz,Vigante B,Duburs G

更新日期：2007-11-01 00:00:00

abstract：:Endothelial dysfunction is recognized as the initial detectable stage of cardiovascular disease, a serious complication of diabetes. In this study, we evaluated effects of myricetin on high glucose (HG)-elicited oxidative damage in human umbilical vein endothelial cells (HUVECs). The cells were pre-incubated with myri...

journal_title：Cell biochemistry and function

authors： Aminzadeh A,Bashiri H

更新日期：2020-01-01 00:00:00

abstract：:Development and homeostasis of multicellular organisms require interactions between neighbouring cells. We recently established an in vitro model of cell-cell interaction based on a collagen vitrigel membrane. We have now examined the role of neural cells in retinal homeostasis by coculture of human retinal pigment ep...

journal_title：Cell biochemistry and function

authors： Ko JA,Hirata J,Yamane K,Sonoda KH,Kiuchi Y

更新日期：2015-01-01 00:00:00

abstract：:The modification of myeloperoxidase and lactoperoxidase with 2-(O-methoxypolethylene glycol)-4, 6-dichloro-s-triazine, an activated polyethylene glycol (PEG1), was investigated. The modification caused a shift of the Soret band in the light absorption spectrum, from 430 nm to 418 nm in the case of myeloperoxidase (nat...

journal_title：Cell biochemistry and function

authors： Odajima T,Onishi M

更新日期：1998-06-01 00:00:00

abstract：:The p53 protein plays a critical role in suppression of tumour growth; its regulation is not fully understood. Leukaemia/lymphoma-related factor (LRF) promotes tumour cell growth. This study tests a hypothesis that LRF inhibits p53 expression in colon cancer cells. In this study, human colon cancer cell lines, LIM1215...

journal_title：Cell biochemistry and function

authors： Zhu M,Wang P,Feng F,Li MY

更新日期：2017-10-01 00:00:00

abstract：:The goal of the study was to estimate the effect of a selective V-type H+ -ATPase inhibitor bafilomycin A1 and nicotinic acid adenine dinucleotide phosphate (NAADP) on energetic processes in NK/Ly cell by directly measuring the respiration of isolated mitochondria and ATPase activities. NAADP (7 μM) increased the acti...

journal_title：Cell biochemistry and function

authors： Hreniukh V,Bychkova S,Kulachkovsky O,Babsky A

更新日期：2016-12-01 00:00:00

abstract：:The use of Nigerian bonny light crude oil (BLCO) in the treatment of gastrointestinal disorders, burns, foot ulcers and reproductive capacity is a common practice in the southern part of Nigeria. Towards understanding the mechanism and the reversibility of hepatotoxicity induced by BLCO, adult male Wistar rats were or...

journal_title：Cell biochemistry and function

authors： Adedara IA,Farombi EO

更新日期：2012-08-01 00:00:00

abstract：:Chemotherapeutic drugs that induce DNA damage have the potential to kill cancer cells, but DNA repair protects cells from damage-induced cell death. Thus, eliminating DNA repair is a potential approach to overcome cell drug resistance. In this study, we observed that the gene expression of C-terminal binding protein i...

journal_title：Cell biochemistry and function

authors： Yang L,Yang B,Wang Y,Liu T,He Z,Zhao H,Xie L,Mu H

更新日期：2019-10-01 00:00:00

abstract：:Thyroid cells fall into the type of cells functioning during continuous production of high H(2)O(2) concentrations. We studied the effect of H(2)O(2)-induced oxidative stress (0.1, 1.0 and 10.0 mM) on the activities of the key steps of iodide metabolism (uptake, oxidation and organification) in thyrocytes cultivated i...

journal_title：Cell biochemistry and function

authors： Nadolnik LI,Niatsetskaya ZV,Lupachyk SV

更新日期：2008-04-01 00:00:00

abstract：:Familial Mediterranean Fever (FMF) is an autosomal recessive hereditary disease leading mostly to renal failure and nephrotic syndrome. The ultrastructure of kidney has not been fully investigated in FMF associated renal disease. The aim of this study is to provide further evidence on the ultrastructure of kidney in p...

journal_title：Cell biochemistry and function

authors： Kiliçaslan SM,Ayvali C,Taştan H

更新日期：2007-07-01 00:00:00

abstract：:Dietary soy lecithin supplementation decreases hyperlipidemia and influences lipid metabolism. Although this product is used by diabetic patients, there are no data about the effect of soy lecithin supplementation on the immune system. The addition of phosphatidylcholine, the main component of lecithin, to a culture o...

journal_title：Cell biochemistry and function

authors： Miranda DT,Batista VG,Grando FC,Paula FM,Felício CA,Rubbo GF,Fernandes LC,Curi R,Nishiyama A

更新日期：2008-12-01 00:00:00

abstract：:We studied the effect of PTH (10-100 nM) on transductive mechanisms (adenylate cyclase activity, Ca2+ metabolism, IP3 levels) in cell cultures derived from normal and otosclerotic human bone fragments. The cultured cells were osteoblast-like but with calcitonin-receptors still present and with PTH receptors coupled wi...

journal_title：Cell biochemistry and function

authors： Fanó G,Venti-Donti G,Belia S,Paludetti G,Antonica A,Donti E,Maurizi M

更新日期：1993-12-01 00:00:00

abstract：:The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both kidney cortex and liver mitochondria. Citrinin promoted a decrease in t...

journal_title：Cell biochemistry and function

authors： Chagas GM,Oliveira MA,Campello AP,Kluppel ML

更新日期：1995-03-01 00:00:00

abstract：:Growth factors are biologically-active mediators that bind to specific receptors on target cells and regulate genes involved in cell growth, wound healing and regeneration. In the case of wound healing, a proper wound dressing is needed to cover the wound area, protect the damaged tissue, and if possible to activate c...

journal_title：Cell biochemistry and function

authors： Grdisa M,Popović M,Hrzenjak T

更新日期：2004-11-01 00:00:00

abstract：:It is generally accepted that hypertension and other vascular pathologies increase in diabetes mellitus (DM) patients as a result of the renin-angiotensin-aldosterone (RAA) system. In this study, changes in the renin-angiotensin-aldosterone (RAA) system level was determined in Streptozotocin (STZ)-injected rats. A tot...

journal_title：Cell biochemistry and function

authors： Ustündag B,Cay M,Naziroglu M,Dilsiz N,Crabbe MJ,Ilhan N

更新日期：1999-09-01 00:00:00

abstract：:Hyperglycemia induces overproduction of superoxide and it is related to diabetic complications. In this study, we analyzed the antioxidant enzymatic defense and the lipid peroxidation of rat salivary glands in six different periods of diabetic condition. Ninety-six rats were divided into 12 groups: C7/14/21/28/45/60 (...

journal_title：Cell biochemistry and function

authors： Ibuki FK,Simões A,Nogueira FN

更新日期：2010-08-01 00:00:00

abstract：:Nuclear, chromatin and microsomal fractions were isolated from hepatocytes prepared from rats injected with [32P]O4(2-) and killed subsequently at times between 1 and 48 h. Specific activities of the total phospholipids (PL) were determined for each subcellular fraction. The major points noted were the initial specifi...

journal_title：Cell biochemistry and function

authors： Viola-Magni MP,Gahan PB,Albi E,Iapoce R,Gentilucci PF

更新日期：1986-10-01 00:00:00