"Let there be bile"--understanding hepatic injury in cholestasis.

abstract：OBJECTIVES:Although rare, carcinoid tumor of the appendix is the most common neoplasm of the gastrointestinal tract in children and adolescents. It is usually an incidental finding after a laparotomy for appendectomy, with a frequency of 2 to 5 cases per 1000 appendectomies. The experience with 14 cases of carcinoid re...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dall'Igna P,Ferrari A,Luzzatto C,Bisogno G,Casanova M,Alaggio R,Terenziani M,Cecchetto G

更新日期：2005-02-01 00:00:00

abstract：:In cholestatic diseases, the absorption of fat-soluble compounds, including vitamin K1(20), is low and periodic administration of vitamin K1(20) is often necessary. Due to the low absorption of vitamin K1(20) from the Konakion formulation, late hemorrhagic disease of the newborn also occurs especially after oral vitam...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Amédée-Manesme O,Lambert WE,Alagille D,De Leenheer AP

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND AIM:Baclofen, a γ-aminobutyric acid receptor agonist, has been shown to reduce the episodes of gastroesophageal reflux (GER) by reducing the incidence of transient lower esophageal sphincter relaxations. Although baclofen has been shown to reduce reflux symptoms in adults, data in pediatric patients are ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vadlamudi NB,Hitch MC,Dimmitt RA,Thame KA

更新日期：2013-12-01 00:00:00

abstract：AIM AND OBJECTIVE:: Chronic models of inflammatory bowel disease are lacking in preadult rodents. The primary goal of our study was to develop a chronic model of hapten-induced intestinal inflammation and fibrosis in young rats. Second, we aimed to determine the profiles of key Th-1, Th-2, and Th-17 proinflammatory and...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fitzpatrick LR,Meirelles K,Small JS,Puleo FJ,Koltun WA,Cooney RN

更新日期：2010-03-01 00:00:00

abstract：:Lactoferrin is an iron-binding protein present in high concentrations in human milk. The efficacy of supplementing iron bound to lactoferrin to iron-deficient and iron-sufficient young mice was evaluated in comparison with supplementation of iron as iron chloride. Mice fed a nonsupplemented milk diet (approximately 1 ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fransson GB,Keen CL,Lönnerdal B

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:There are few studies of Helicobacter pylori reinfection in childhood. In the current study the reinfection rate of H. pylori and ulcer recurrence were investigated during a follow-up period of 12 months or more in children who had undergone eradication therapy. METHODS:Twenty-seven patients aged 5 to 16 ye...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kato S,Abukawa D,Furuyama N,Iinuma K

更新日期：1998-11-01 00:00:00

abstract：:Pancreatic pseudocyst is a know complication of acute pancreatitis and pancreatic trauma. The treatment of pancreatitis remains a challenge and the pancreatic pseudocyst is often approached surgically. Lately, the use of somatostatin and its long-acting analogue octreotide have proved useful in the treatment of pancre...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bosman-Vermeeren JM,Veereman-Wauters G,Broos P,Eggermont E

更新日期：1996-11-01 00:00:00

abstract：:Pseudomembranous colitis secondary to C. difficile and its toxin(s) is a well-recognized disease in children and usually responds to treatment with oral vancomycin. There are well-documented reports of relapse in adults after initial successful treatment with vancomycin. This report documents relapse in a child who de...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Holmes R,Byrne WJ

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVE:By reviewing the literature, lessons learned and experience regarding the nutrition-related health problems of preschool children, draw conclusions and make recommendations on education and nutrition policies for young children. RESULTS:The most common causes of under-5 mortality in low-income countries have...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Darnton-Hill I,Kennedy E,Cogill B,Hossain SM

更新日期：2006-12-01 00:00:00

abstract：:During two treatment periods (4 weeks each), serum immunoreactive trypsin (IRT), immunoreactive human lipase in stool (IRL), and chymotrypsin (CT) activity in stool were determined in 16 cystic fibrosis patients and compared with fecal fat excretion (72-h sampling). Fecal fat estimation revealed mild to severe steator...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Regele S,Henker J,Münch R,Barbier Y,Stern M

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:In traditional access endoscopy (TAE), patients are booked for endoscopy following a gastroenterology clinic assessment. In contrast, open access endoscopy (OAE) patients are seen for the first time on the day of the procedure, providing same day procedural consent. Controversy exists over the use of OAE in ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Isaac DM,Persad R,Huynh HQ,Shirton L,Turner JM

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:Gliadin proteins play a key role in the pathogenesis of celiac disease; however, as a screen for celiac disease, anti-gliadin antibody testing has been replaced by the more sensitive and specific serological assays for transglutaminase autoantibodies (TGAA). A new generation of anti-gliadin antibody assays...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Liu E,Li M,Emery L,Taki I,Barriga K,Tiberti C,Eisenbarth GS,Rewers MJ,Hoffenberg EJ

更新日期：2007-09-01 00:00:00

abstract：:We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patien...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Schoepfer AM,Vavricka S,Safroneeva E,Fournier N,Manser C,Frei P,Deltenre P,Rogler G,Straumann A,Ezri J,Nydegger A,Braegger C

更新日期：2017-02-01 00:00:00

abstract：:Acute hydrops of the gallbladder is a well-recognized complication of Kawasaki syndrome. We report a case of a child with this syndrome whose gallbladder hydrops slowly resolved after intravenous gamma-globulin therapy. However, he continued to experience postprandial right upper quadrant abdominal pain. Hepatobiliary...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bishop WP,Kao SC

更新日期：1991-10-01 00:00:00

abstract：:We describe a premature infant with cholestatic liver disease and protease inhibitor MS phenotype. This infant demonstrated an abnormally low serum alpha 1-antitrypsin concentration. Liver histologic studies revealed diastase-resistant, periodic acid-Schiff-positive globules inside hepatocytes. Immunoperoxidase staini...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gourley MF,Gourley GR,Gilbert EF,Odell GB

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the efficacy and safety of cyproheptadine (CY) use in infants and young children with poor growth treated at our multidisciplinary pediatric feeding program, and to describe changes in their weight and feeding behaviors. METHODS:A retrospective chart review of children tre...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sant'Anna AM,Hammes PS,Porporino M,Martel C,Zygmuntowicz C,Ramsay M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In the last 10 years, there have been an increasing number of case reports concerning gastrointestinal injury related to magnet ingestions; however, the magnitude of the problem remains to be clearly defined. The aim of the study was to examine the epidemiology of magnet ingestion-related emerg...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Abbas MI,Oliva-Hemker M,Choi J,Lustik M,Gilger MA,Noel RA,Schwarz K,Nylund CM

更新日期：2013-07-01 00:00:00

abstract：:The effect of protein-calorie malnutrition during gestation on the brain amino acids of rat pups was studied following nutritional recovery during lactation. The brain amino acids of rat pups born to dam rats malnourished during gestation were studied after these rat pups received proper nutrition during lactation. Pr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Trindade CE,de Nóbrega FJ,Tonete SS,Sartor ME,Curi PR

更新日期：1984-11-01 00:00:00

abstract：:Histologic assessment as well as information about the disaccharidase activity of the small intestinal mucosa can be useful in the management of patients with small intestinal mucosal damage. In an effort to determine whether the degree of small intestinal mucosal damage would be reflected in a corresponding reduction...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shulman RJ,Langston C,Lifschitz CH

更新日期：1991-01-01 00:00:00

abstract：:Quality training in pediatric gastroenterology, hepatology, and nutrition is essential for the future of our specialty from advancing the science through research to providing clinical care for children with gastrointestinal, hepatic and nutritional disorders. As educational theory has developed, both the American Boa...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sauer CG,Robson J,Turmelle YP,Cerezo CS,Loomes KM,Huang JS,Quiros-Tejeira RE,Benkov KJ,Narkewicz MR,Leichtner A,Weinstein T

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The efficacy of a 1-week "triple therapy" in children with Helicobacter pylori gastritis and recurrent abdominal pain was studied. The effect of treatment was also studied in correlation to recurrent abdominal pain. METHODS:Thirty-two children with recurrent abdominal pain were investigated with H. pylori s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Casswall TH,Alfvén G,Drapinski M,Bergström M,Dahlström KA

更新日期：1998-10-01 00:00:00

abstract：:Membrane distribution in human milk was investigated. Milk samples from six women taken at intervals throughout 9 months of lactation were fractionated into fat globules, skim milk, fluff, and cells. These fractions and the intact milks were analyzed for protein, total lipid, and membrane material as revealed by phosp...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Huston GE,Patton S

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to examine the effects of early and high intravenous (IV) amino acid (AA) supplementation on growth, health, and neurodevelopment of extremely-low-birth-weight (ELBW) infants throughout their first 2 years of life. METHODS:Infants were prospectively randomized in a double-mas...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Blanco CL,Gong AK,Schoolfield J,Green BK,Daniels W,Liechty EA,Ramamurthy R

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Although perianal complications of Crohn disease (CD) are commonly encountered in clinical practice, the epidemiology of perianal CD among populations of children is poorly understood. We sought to characterize the prevalence of perianal disease in a large and diverse population of pediatric patients with CD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Adler J,Dong S,Eder SJ,Dombkowski KJ,ImproveCareNow Pediatric IBD Learning Health System.

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:There is increasing interest in measuring mucosal inflammation in Crohn disease (CD), but there are minimal data correlating the Pediatric Crohn's Disease Activity Index (PCDAI) versions (PCDAI, weighted Pediatric Crohn's Disease Activity Index [wPCDAI], abbreviated Pediatric Crohn's Disease Activity Index...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Turner D,Levine A,Walters TD,Focht G,Otley A,López VN,Koletzko S,Baldassano R,Mack D,Hyams J,Griffiths AM

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The response of serum transaminase levels to penicillamine and zinc treatment in Wilson's disease is poorly understood. The aim of this multicenter retrospective study was to evaluate transaminase levels after penicillamine and zinc treatment in children with Wilson's disease. PATIENTS AND METHODS:One hundr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Iorio R,D'Ambrosi M,Marcellini M,Barbera C,Maggiore G,Zancan L,Giacchino R,Vajro P,Marazzi MG,Francavilla R,Michielutti F,Resti M,Frediani T,Pastore M,Mazzarella G,Fusco G,Cirillo F,Vegnente A,Hepatology Committee of

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:Oxidative stress has been implicated in the development of nonalcoholic fatty liver disease (NAFLD) and progression to the more severe form, nonalcoholic steatohepatitis (NASH), in children. We aimed to study the clinical correlation between bilirubin, a potent endogenous antioxidant with cytoprotective prop...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Puri K,Nobili V,Melville K,Corte CD,Sartorelli MR,Lopez R,Feldstein AE,Alkhouri N

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Familial intrahepatic cholestasis 1 (FIC1) deficiency is caused by a mutation in the ATP8B1 gene. Partial external biliary diversion (PEBD) is pursued to improve pruritus and arrest disease progression. Our aim is to describe clinical variability after PEBD in FIC1 disease. METHODS:We performed a single-cen...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Squires JE,Celik N,Morris A,Soltys K,Mazariegos G,Shneider B,Squires RH

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Electrolyte-free polyethylene glycol powder (PEG-3350) has been widely used for colonoscopy preparation (prep); however, limited safety data on electrolyte changes exists with 1-day prep regimens. The primary aim of this study was to determine the proportion of patients with significant serum chemistry abnor...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sahn B,Chen-Lim ML,Ciavardone D,Farace L,Jannelli F,Nieberle M,Ely E,Zhang X,Kelsen J,Puma A,Mamula P

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Senna laxatives are used worldwide. However, their misuse can lead to chronic mucosal inflammation with the accumulation of pigment-laden leukocytes and may cause colon cells to undergo apoptosis. This study explores the mechanisms by which rhein, an active component of senna, acts on a human intestinal cell...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Raimondi F,Santoro P,Maiuri L,Londei M,Annunziata S,Ciccimarra F,Rubino A

更新日期：2002-05-01 00:00:00