Effect of plantain on therapeutic drug monitoring of digoxin and thirteen other common drugs.

abstract：:Circulating insulin-like growth factor-1 (IGF-1) is increasingly being used as a screening test and in ongoing monitoring of treated acromegaly. We here present three cases of women (two of whom were on the oestrogen containing contraceptive pill at the time of presentation) who had normal circulating IGF-1 and no ove...

journal_title：Annals of clinical biochemistry

authors： Kalavalapalli S,Reid H,Kane J,Buckler H,Trainer P,Heald AH

更新日期：2007-01-01 00:00:00

abstract：:We examined the reactivity of human serum albumin-bound bilirubin and its photoisomers as substrates for a direct bilirubin assay using bilirubin oxidase. The reduction of (EZ)-cyclobilirubin reached 100% 5 min after addition of the enzyme at any pH tested (3.5-7.4) in 0.1 mol/L phosphate buffer, whereas the reduction...

journal_title：Annals of clinical biochemistry

authors： Itoh S,Kusaka T,Imai T,Isobe K,Onishi S

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:To date, the difference in microRNA expression profiles in tears of dry eye patients and healthy people has not been reported. In current study, we evaluated the significance of microRNAs and transforming growth factor beta2 (TGF-β2) in distinguishing dry eye. METHODS:A total of 138 patients with dry eye fr...

journal_title：Annals of clinical biochemistry

authors： Wang Q,Xie X,Li H,Hao S

更新日期：2020-11-01 00:00:00

abstract：:It is crucially important to detect subarachnoid haemorrhage (SAH) in all patients in whom it has occurred to select patients for angiography and preventative surgery. A computerized tomography (CT) scan is positive in up to 98% of patients with SAH presenting within 12 h, but is positive in only 50% of those presenti...

journal_title：Annals of clinical biochemistry

authors： Cruickshank A,Auld P,Beetham R,Burrows G,Egner W,Holbrook I,Keir G,Lewis E,Patel D,Watson I,White P,UK NEQAS Specialist Advisory Group for External Quality Assurance of CSF Proteins and Biochemistry.

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The pneumatic tube system (PTS) has been implicated in inducing haemolysis. It is not known whether certain sample types are more susceptible to haemolysis than others. We assessed the level of haemolysis in commonly used sample types in the clinical biochemistry department when transported through the PTS. ...

journal_title：Annals of clinical biochemistry

authors： Sodi R,Darn SM,Stott A

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Patients with Crigler-Najjar syndrome, type I (CNS-I) have an inherited absence of hepatocellular bilirubin uridine diphosphate-glucuronosyltransferase activity, which results in severe unconjugated hyperbilirubinaemia, often causing kernicterus and death in infancy or childhood. METHODS:Our patient is a 19...

journal_title：Annals of clinical biochemistry

authors： Ihara H,Shino Y,Hashizume N,Shimizu N,Aoki T,Yoshida M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumours are slow growing tumours known to secrete a variety of vasoactive peptides which give rise to symptoms of the carcinoid syndrome. The diagnosis and monitoring of patients with neuroendocrine tumours is undertaken in many centres using 24 h urinary measurement of 5-hydroxyindoleacetic a...

journal_title：Annals of clinical biochemistry

authors： Adaway JE,Dobson R,Walsh J,Cuthbertson DJ,Monaghan PJ,Trainer PJ,Valle JW,Keevil BG

更新日期：2016-09-01 00:00:00

abstract：:The last 10 years have witnessed radical changes in the definition and diagnosis of the acute coronary syndrome (ACS), including myocardial infarction, as a result of the introduction of sensitive and specific markers of myocardial damage, the cardiac troponins. One barrier to the universal acceptance of these markers...

journal_title：Annals of clinical biochemistry

authors： Lamb EJ,Webb MC,Abbas NA

更新日期：2004-01-01 00:00:00

abstract：:A high-pressure liquid chromatography procedure for the measurement of free catecholamines in urine is described. 'On-line' sample preparation using a cartesian robot combined with the ASTED process ensures minimal operator intervention and reduced costs. ...

journal_title：Annals of clinical biochemistry

authors： Green B,Cooper JD,Turnell DC

更新日期：1989-07-01 00:00:00

abstract：:Erythrocuprein (superoxide dismutase) has recently been shown to have an enzymic function towards superoxide anions. The discovery of superoxide dismutase, its mode of action, and estimation are reviewed along with a brief introduction to oxygen activation and free-radical chemistry. The formation, activity, and destr...

journal_title：Annals of clinical biochemistry

authors： Gutteridge JM

更新日期：1976-05-01 00:00:00

abstract：:The diagnostic usefulness of fasting total serum bile acids (SBA/F) in the detection of liver diseases and assessment of different aspects of hepatic function alteration was evaluated in 61 healthy subjects and 186 patients with liver disease. The value of SBA/F was compared with other routine tests. In 49 healthy sub...

journal_title：Annals of clinical biochemistry

authors： Cravetto C,Molino G,Biondi AM,Cavanna A,Avagnina P,Frediani S

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Placental growth factor (PlGF) and soluble-fms-like tyrosine kinase 1 (sFlt-1) are biomarkers of placental function used to aid the diagnosis and prediction of pregnancy complications. This work verified the analytical performance of both biomarkers and provides preliminary diagnostic accuracy data to identi...

journal_title：Annals of clinical biochemistry

authors： Armstrong-Buisseret LK,Haslam S,James T,Bradshaw L,Heazell AE

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:To assess the accuracy and precision of the Roche Performa and Medisense Optium Xceed (5 and 10 s reading) blood glucose meters. METHODS:Capillary blood samples were taken from 100 patients attending a diabetes centre and blood glucose measured on Roche Performa (n = 4) and Medisense Optium Xceed 5 s (n = 2...

journal_title：Annals of clinical biochemistry

authors： Florkowski C,Budgen C,Kendall D,Lunt H,Moore MP

更新日期：2009-07-01 00:00:00

abstract：:The content of cytoplasmic 17 beta oestradiol and progesterone receptors in human uterine leiomyoma and normal myometrium in the Negroid population was determined. Eighteen women of reproductive age, at various stages of the menstrual cycle, were included in the study. The serum oestrogen and progesterone concentratio...

journal_title：Annals of clinical biochemistry

authors： Sadan O,van Iddekinge B,van Gelderen CJ,Savage N,Becker PJ,van der Walt LA,Robinson M

更新日期：1987-05-01 00:00:00

abstract：:Hereditary renal hypouricaemia (HRH) is a genetic disorder commonly associated with exercise-induced acute kidney injury (AKI). We report the case of a 19-year-old man who was admitted to hospital with exercise-induced AKI and who was subsequently shown to have HRH. We believe this to be the first description of a cas...

journal_title：Annals of clinical biochemistry

authors： Chakraborty S,Sural S

更新日期：2013-05-01 00:00:00

abstract：:Antibodies to glutamic acid decarboxylase (GAD) are a useful autoimmune marker for type 1 diabetes mellitus in Caucasians. We examined antibodies to GAD and their relationships with clinical features and pancreatic beta cell function in 140 young Chinese diabetic patients. Over an 18-month period beginning in 1995, 14...

journal_title：Annals of clinical biochemistry

authors： Ko GT,Chan JC,Yeung VT,Chow CC,Li JK,Lau MS,Mackay IR,Rowley MJ,Zimmet P,Cockram CS

更新日期：1998-11-01 00:00:00

abstract：:Parenteral nutrition is a well-established technique for feeding patients with intestinal failure and other conditions which render enteral feeding impossible. Biochemical tests are required in the initial assessment of these patients, for monitoring their response to treatment and for the detection and management of ...

journal_title：Annals of clinical biochemistry

authors： Marshall WJ,Mitchell PE

更新日期：1987-07-01 00:00:00

abstract：:The hypoglycaemia caused by non-islet cell tumours is often associated with an increase in plasma insulin-like activity. In many cases there is a relative if not always absolute increase in plasma insulin-like growth factor II (IGF-II). Growth hormone (GH) secretion is almost invariably depressed as is the plasma insu...

journal_title：Annals of clinical biochemistry

authors： Teale JD,Blum WF,Marks V

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND METHODS:We report a case of insulinoma in which the diagnosis was very challenging as some of the biochemical data were consistently equivocal. In order to assess the relative reliability of the analytical tests, retrospective biochemical data on 45 other cases of histologically confirmed insulinoma were...

journal_title：Annals of clinical biochemistry

authors： Chammas NK,Teale JD,Quin JD

更新日期：2003-11-01 00:00:00

abstract：:The development and evaluation in routine clinical practice of a simple, rapid, high-throughput, immunoradiometric assay (IRMA) for alpha-foetoprotein (AFP) in serum and amniotic fluid is described. The assay uses readily available reagents; a radioiodinated mouse monoclonal antibody produced by the authors and the im...

journal_title：Annals of clinical biochemistry

authors： Stevenson JD,Chapman RS,Perry B,Logue FC

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:We evaluated the recently released chemiluminescence assay for 25-hydroxy vitamin D (25-OHD) on the Immunodiagnostic Systems iSYS (IDS-iSYS) automated analyser. METHODS:The IDS-iSYS comparison was performed using patient samples previously measured for 25-OHD by a validated liquid chromatography-tandem mass...

journal_title：Annals of clinical biochemistry

authors： Cluse ZN,Fudge AN,Whiting MJ,McWhinney B,Parkinson I,O'Loughlin PD

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:It is important to explain target proteins for the understanding of the pathogenesis of vitreoretinal diseases. In a previous study, we identified more than 100 proteins including seven angiogenic-modulated factors in vitreous humours (VHs). Although there have been many reports of expressed protein profiles...

journal_title：Annals of clinical biochemistry

authors： Mukai N,Nakanishi T,Shimizu A,Takubo T,Ikeda T

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:To know whether metformin improves postprandial hyperglycaemia, we examined the effect of metformin on the glycated albumin (GA) to glycated haemoglobin (HbA1c) ratio (GA/HbA1c ratio) in patients with newly diagnosed type 2 diabetes. METHODS:Metformin and lifestyle interventions were initiated in 18 patient...

journal_title：Annals of clinical biochemistry

authors： Sumitani S,Morita S,Deguchi R,Hirai K,Mukai K,Utsu Y,Miki S,Sato B,Nakamura H,Kasayama S,Koga M

更新日期：2015-01-01 00:00:00

abstract：:Measurement of urinary free cortisol using the Bayer Automated Chemiluminescent System (ACS:180 PLUS) was evaluated and compared with an in-house extraction radioimmunoassay (RIA). Inter-assay coefficients of variation were acceptable, being respectively 5.3%, 4.8% and 3.8% at 141, 406 and 942 nmol/L (n=20) for the AC...

journal_title：Annals of clinical biochemistry

authors： Kennedy DM,Selby C,Lawson N

更新日期：2000-07-01 00:00:00

abstract：:Background Measured (MO) and calculated osmotic concentrations (CO) and the osmotic gap (OG) are commonly used in the investigation of electrolyte and volume disturbances as well as in cases of suspected volatile ingestion. Methods We compared 38 published formulae for CO with MO on a large data-set ( n = 9466) and ad...

journal_title：Annals of clinical biochemistry

authors： Wilgen U,Pretorius CJ,Ungerer JP

更新日期：2018-01-01 00:00:00

abstract：:The estimation of oestrogen in aqueous solutions and pregnancy urines using an automated procedure is affected by the presence of certain ions, and by dilution. These effects have been studied by calculating regression equations from the values obtained with urines to which ions have been added with and without urine ...

journal_title：Annals of clinical biochemistry

authors： Simkins A,Worth HG

更新日期：1976-01-01 00:00:00

abstract：:γ-glutamyltransferase plays a key role in the synthesis and metabolism of extracellular glutathione, a major antioxidant in several defence mechanisms in the body. γ-glutamyltransferase is affected by environmental and genetic factors, and is raised when there is depletion of glutathione. Hence, it is a marker of oxid...

journal_title：Annals of clinical biochemistry

authors： Bulusu S,Sharma M

更新日期：2016-05-01 00:00:00

abstract：:Background Detection of alcohol consumption in clients undergoing treatment for alcohol dependence can be difficult. The ethanol metabolites ethyl glucuronide and ethyl sulphate are detectable for longer in urine than either breath ethanol or urine ethanol. Our aim was to develop a liquid chromatography-tandem mass sp...

journal_title：Annals of clinical biochemistry

authors： Armer JM,Allcock RL

更新日期：2017-01-01 00:00:00

abstract：:The effect of progestins on intracellular corticosteroid-binding globulin (CBG) mRNA expression in an endometrial cancer cell line (Ishikawa) was examined in an attempt to understand the biological effects of high-dose progestins in the treatment of well-differentiated uterine endometrial cancers. Oestradiol-17 beta (...

journal_title：Annals of clinical biochemistry

authors： Misao R,Nakanishi Y,Fujimoto J,Tamaya T

更新日期：1998-09-01 00:00:00

abstract：:Background After adrenalectomy, urinary fractionated metanephrine concentrations are expected to be reduced. However, there are few studies suggesting cut-offs for adrenalectomy patients. Methods Urinary metanephrine and normetanephrine concentrations in adrenalectomy patients and two controls were compared and hormon...

journal_title：Annals of clinical biochemistry

authors： Cho YY,Kim YN,Kim JH,Jeong BC,Lee SY,Kim JH

更新日期：2017-01-01 00:00:00