Single photon emission computed tomography with Tc-99m-dimercaptosuccinic acid in patients with upper urinary tract infection and/or vesicoureteral reflux.


:By means of Tc-99m dimercaptosuccinic acid (DMSA) scintigraphy, an established method for assessing renal cortical damage, we evaluated the pick-up rate for renal defects (scars) by single photon computed tomography (SPECT) and planar images of 10 normal volunteers, and 58 patients (70 scintigrams) with upper urinary tract infections, most of whom had a history of vesicoureteral reflux (VUR). The positive study rate for renal defects depended on the severity of VUR. The overall positive rates for renal cortical defects obtained by DMSA SPECT imaging and DMSA planar imaging were 60% and 43%, respectively, and the difference between these was significant (p less than 0.005). The mean absolute individual renal uptake (/injected dose) at 2 hours post-injection was decreased in kidneys with defects detected by SPECT alone. The positive study rate for intravenous urography (IVU) depended on the grade of VUR and was 15% overall. DMSA SPECT imaging detects renal cortical defects at greater frequency than previously achieved.


Ann Nucl Med


Itoh K,Asano Y,Tsukamoto E,Kato C,Nakada K,Nagao K,Furudate M,Gotoh T,Nonomura K,Koyanagi T




Has Abstract,Author List Incomplete


1991-03-01 00:00:00












  • Coincidental visualization of an atypical bronchial carcinoid on Tc-99m-sestamibi scan in Kallmann's syndrome.

    abstract::We report a case of an atypical bronchial carcinoid showing sestamibi uptake. A 27-year-old man with Kallmann's syndrome and hyperparathyroidism had parathyroid scintigraphy with 99mTc-sestamibi. A focal uptake was observed on the right perihilar region, and this right perihilar mass was demonstrated on computed tomog...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Yapar Z,Kibar M,Sükan A,Paydaş S,Zeren H,Inal M

    更新日期:2002-02-01 00:00:00

  • Evaluation of pleural lesions after pleurodesis with OK-432 by fluorodeoxyglucose-positron emission tomography/CT.

    abstract:OBJECTIVE:This study aimed to determine changes in FDG-PET/CT after pleurodesis with OK-432 and to investigate differences in the changes between non-malignant and malignant lesions. METHODS:Study participants were 17 patients with a history of malignant chest disease who underwent FDG-PET/CT after pleurodesis using O...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Nishimori M,Yoshimatsu R,Iwasa H,Miyatake K,Nitta N,Anayama T,Yamagami T

    更新日期:2020-10-01 00:00:00

  • CT-based SPECT attenuation correction and assessment of infarct size: results from a cardiac phantom study.

    abstract:RATIONALE:Myocardial perfusion SPECT is a commonly performed, well established, clinically useful procedure for the management of patients with coronary artery disease. However, the attenuation of photons from myocardium impacts the quantification of infarct sizes. CT-Attenuation Correction (AC) potentially resolves th...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Kroiss AS,Nekolla SG,Dobrozemsky G,Grubinger T,Shulkin BL,Schwaiger M

    更新日期:2017-12-01 00:00:00

  • Quantifying regional cerebral blood flow with N-isopropyl-p[123I]iodoamphetamine by ring-type single-photon emission computed tomography: validity of a method to estimate early reference value by means of regional brain time-activity curve.

    abstract::A more accurate quantitative method for the measurement of regional cerebral blood flow (rCBF) with the microsphere model and N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) and ring-type single-photon emission computed tomography (SPECT) was developed. Continuous withdrawal of arterial blood was carried out for 5 minu...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Takahashi N

    更新日期:1994-11-01 00:00:00

  • Assessment of human effective absorbed dose of 67 Ga-ECC based on biodistribution rat data.

    abstract:OBJECTIVE:In a diagnostic context, determination of absorbed dose is required before the introduction of a new radiopharmaceutical to the market to obtain marketing authorization from the relevant agencies. In this work, the absorbed dose of [67 Ga]-ethylenecysteamine cysteine [(67 Ga)ECC] to human organs was determine...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Shanehsazzadeh S,Yousefnia H,Lahooti A,Zolghadri S,Jalilian AR,Afarideh H

    更新日期:2015-02-01 00:00:00

  • High metabolic tumor volume and total lesion glycolysis are associated with lateral lymph node metastasis in patients with incidentally detected thyroid carcinoma.

    abstract:OBJECTIVE:The objective of this study was to investigate whether total lesion glycolysis (TLG) and metabolic tumor volume (MTV) measured by ¹⁸F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) could predict the aggressiveness and lymph node metastasis (LNM) in patients with incid...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Kim BH,Kim SJ,Kim K,Kim H,Kim SJ,Kim WJ,Jeon YK,Kim SS,Kim YK,Kim IJ

    更新日期:2015-10-01 00:00:00

  • Gallium-67 scintigraphic findings in a patient with breast lymphoma complicated with Sjögren syndrome.

    abstract::We report here a patient with mucosa associated lymphoid tissue (MALT)-lymphoma of the breast complicated with Sjögren syndrome. It is speculated that Ga-67 could accumulate not only in lymphoma lesions but also in benign lymphoproliferative locations of Sjögren syndrome. Gallium-67 scintigraphy might be useful for th...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Yoshimura M,Koizumi K,Satani K,Kakizaki D,Kawanishi Y,Ohyashiki K,Abe K

    更新日期:2000-06-01 00:00:00

  • Evaluation of 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography in gastric carcinoma: relation to histological subtypes, depth of tumor invasion, and glucose transporter-1 expression.

    abstract:OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Yamada A,Oguchi K,Fukushima M,Imai Y,Kadoya M

    更新日期:2006-11-01 00:00:00

  • High detection sensitivity and reliable morphological correlation of PET with a silicon photomultiplier for primary tongue squamous cell carcinoma.

    abstract:OBJECTIVE:A positron emission tomography (PET) scanner using a silicon photomultiplier (SiPM PET) in place of a photomultiplier tube significantly improves the spatial and time resolution. It may also improve the evaluation of smaller lesions compared to conventional (non-SiPM) PET scanners. We compared the maximum sta...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Kojima I,Takanami K,Ogawa T,Sakamoto M,Nagai H,Miyashita H,Iikubo M

    更新日期:2020-09-01 00:00:00

  • Cold tuberculous abscess identified by FDG PET.

    abstract::We report FDG PET of two cases of cold abscess due to Mycobacterium tuberculosis. Case 1 had colon cancer; FDG PET showed high FDG uptake in the colon lesion and low uptake in the inguinal lesion. The latter was a tuberculous cold abscess confirmed by CT/MRI and biopsy. Case 2 received radiotherapy for lung cancer and...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Yago Y,Yukihiro M,Kuroki H,Katsuragawa Y,Kubota K

    更新日期:2005-09-01 00:00:00

  • Can (18)F-FDG-PET/CT be generally recommended in patients with differentiated thyroid carcinoma and elevated thyroglobulin levels but negative I-131 whole body scan?

    abstract:BACKGROUND:Exact localization of recurrent iodine-negative thyroid cancer is mandatory, since surgery is the only curative therapy option in patients with iodine-negative tumor tissue. The aim of this study was to evaluate the impact of (18)F-FDG-PET/CT as a routine diagnostic tool on clinical management in patients wi...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Bannas P,Derlin T,Groth M,Apostolova I,Adam G,Mester J,Klutmann S

    更新日期:2012-01-01 00:00:00

  • Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT.

    abstract::18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevate...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Chen CJ,Yao WJ,Chou CY,Chiu NT,Lee BF,Wu PS

    更新日期:2008-07-01 00:00:00

  • Uptake and washout of I-123-MIBG in neuronal and non-neuronal sites in rat hearts: relationship to renal clearance.

    abstract::We investigated the uptake and washout of I-123-metaiodobenzylguanidine (MIBG) in neuronal (both intra- and extravesicular) and non-neuronal sites in the heart and its relationship to renal clearance. Acute renal failure was induced in rats by ligating the renal vessels, and the findings were compared with those of sh...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Arbab AS,Koizumi K,Araki T

    更新日期:1996-05-01 00:00:00

  • Bone metabolic markers as gauges of metastasis to bone: a review.

    abstract::Currently, imaging techniques are the leading methods used to diagnose of metastasis to bone. However, these techniques are expensive, expose patients to toxic and radioactive compounds, and monitor response to treatment poorly; these drawbacks have prompted the search for alternative screening methods. Therefore, bon...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审


    authors: Koizumi M,Ogata E

    更新日期:2002-05-01 00:00:00

  • Novel algorithm for quantitative assessment of left ventricular dyssynchrony with ECG-gated myocardial perfusion SPECT: useful technique for management of cardiac resynchronization therapy.

    abstract:OBJECTIVES:Cardiac resynchronization therapy (CRT) is the established treatment for patients with chronic and severe heart failure, and it has been reported that the presence of left ventricular (LV) dyssynchrony is one of the most important factors which predict positive response of this therapy. In the present study,...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章


    authors: Kiso K,Imoto A,Nishimura Y,Kanzaki H,Noda T,Kamakura S,Ishida Y

    更新日期:2011-12-01 00:00:00

  • Early and delayed Tc-99m-tetrofosmin myocardial SPECT in patients with left bundle branch block.

    abstract:UNLABELLED:To determine the utility of the myocardial tracer Tc-99m-tetrofosmin in the examination of patients with left bundle branch block (LBBB) and to investigate Tc-99m-tetrofosmin uptake and retention in the myocardium, early and delayed Tc-99m-tetrofosmin SPECT was performed in 10 patients having LBBB without co...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Sugihara H,Kinoshita N,Adachi Y,Taniguchi Y,Ohtsuki K,Azuma A,Adachi H,Ushijima Y,Nakagawa M,Maeda T

    更新日期:1998-10-01 00:00:00

  • Inferior mesenteric varix demonstrated by 99mTc-red blood cell gastrointestinal bleeding study.

    abstract::Reported here is a case of an inferior mesenteric varix demonstrated by 99mTc-red blood cell (RBC) scintigraphy performed for gastrointestinal bleeding in a 47-year-old man. It was shaped like a question mark ranging from the left upper abdomen to the pelvis. This is the first report of scintigraphic recognition of an...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Yoshikai T,Yokomizo Y,Iwashita I,Okada Y,Koga H,Kudo S

    更新日期:1997-05-01 00:00:00

  • Comparison between single photon emission computed tomography with computed tomography and planar scintigraphy in sentinel node biopsy in breast cancer patients.

    abstract:OBJECTIVE:Radio-guided sentinel node (SN) biopsy is a standard method used in the treatment of early breast cancer. Single photon emission computed tomography with computed tomography (SPECT/CT) has been commonly used for SN detection. SPECT/CT adds precise anatomical information of SN sites, and it is reported that mo...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Koizumi M,Koyama M

    更新日期:2019-03-01 00:00:00

  • Prospective evaluation of solitary thyroid nodule on 18F-FDG PET/CT and high-resolution ultrasonography.

    abstract:PURPOSE:The utility of 18F-FDG PET/CT in the assessment of thyroid nodules is unclear as there are several conflicting reports on the usefulness of SUV as an indicator to distinguish benign from malignant thyroid lesions. This study incorporated an additional parameter, namely dual time point imaging, to determine the ...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章


    authors: D'Souza MM,Marwaha RK,Sharma R,Jaimini A,Thomas S,Singh D,Jain M,Bhalla PJ,Tripathi M,Tiwari A,Mishra A,Mondal A,Tripathi RP

    更新日期:2010-06-01 00:00:00

  • Efficacy of conventional whole-body ¹⁸F-FDG PET/CT in the incidental findings of parotid masses.

    abstract:OBJECTIVE:The objective of this study was to evaluate the incidence of incidental parotid masses with conventional whole-body ¹⁸F-deoxyglucose (FDG) PET/CT and assess the ability of PET/CT to characterize these unexpected parotid lesions. METHODS:Fifty eight incidental findings of parotid masses with routine FDG PET/C...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Wang HC,Zuo CT,Hua FC,Huang ZM,Tan HB,Zhao J,Guan YH

    更新日期:2010-10-01 00:00:00

  • Occult myofibroblastic sarcoma detected on FDG-PET performed for cancer screening.

    abstract::We present a rare case of occult low-grade myofibroblastic sarcoma (LGMFS) detected by marked 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) uptake on positron emission tomography (PET). A 46-year-old woman presented with abnormal FDG uptake in her back when FDG-PET was performed for cancer screening. The maximum stan...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Morii T,Mochizuki K,Sano H,Fujino T,Harasawa A,Satomi K

    更新日期:2008-11-01 00:00:00

  • Static and moving phantom studies for radiation treatment planning in a positron emission tomography and computed tomography (PET/CT) system.

    abstract:OBJECTIVE:To determine an appropriate threshold value for delineation of the target in positron emission tomography (PET) and to investigate whether PET can delineate an internal target volume (ITV), a series of phantom studies were performed. METHODS:An ellipse phantom (background) was filled with 1028 Bq/ml of [(18)...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Okubo M,Nishimura Y,Nakamatsu K,Okumura M,Shibata T,Kanamori S,Hanaoka K,Hosono M

    更新日期:2008-08-01 00:00:00

  • Comparison of (99m)Tc-labeled PR81 and its F(ab')₂ fragments as radioimmunoscintigraphy agents for breast cancer imaging.

    abstract:OBJECTIVE:We digested anti-MUC1 monoclonal antibody PR81 to produce F(ab')₂ fragments. A comparison was performed between the two radiolabeled PR81 and F(ab')₂ fragments for breast tumor imaging in a mouse model. METHODS:The optimum conditions for pepsin digestion of PR81 were investigated in terms of enzymes: antibod...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Salouti M,Babaei MH,Rajabi H,Foroutan H,Rasaee MJ,Rajabi AB,Mohammadnejad J,Shafiee M,Mazidi M,Daha FJ

    更新日期:2011-02-01 00:00:00

  • The search for consistency in the manufacture of PET radiopharmaceuticals.

    abstract::Nuclear Medicine is the specialty of medical imaging, which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and therapeutic applications. During recent years, research efforts in this discipline have concentrated on the decay characteristics of particular radionuclides a...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审


    authors: Finn RD

    更新日期:1999-12-01 00:00:00

  • Prognostic implications of 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) PET/CT in patients with glioma.

    abstract:OBJECTIVE:The potential of positron emission tomography/computed tomography using 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM PET/CT), which was originally developed as a hypoxic tracer, to predict therapeutic resistance and prognosis has been reported in various cancers. Our purpose was to investigate pr...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章


    authors: Toriihara A,Ohtake M,Tateishi K,Hino-Shishikura A,Yoneyama T,Kitazume Y,Inoue T,Kawahara N,Tateishi U

    更新日期:2018-05-01 00:00:00

  • Computer-aided diagnosis system for bone scintigrams from Japanese patients: importance of training database.

    abstract:AIM:Computer-aided diagnosis (CAD) software for bone scintigrams have recently been introduced as a clinical quality assurance tool. The purpose of this study was to compare the diagnostic accuracy of two CAD systems, one based on a European and one on a Japanese training database, in a group of bone scans from Japanes...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Horikoshi H,Kikuchi A,Onoguchi M,Sjöstrand K,Edenbrandt L

    更新日期:2012-10-01 00:00:00

  • PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging.

    abstract::Physiological functions (e.g., cerebral blood flow, glucose metabolism, and neuroreceptor binding) can be investigated as parameters estimated by kinetic modeling using dynamic positron emission tomography (PET) images. Imaging of these physiological parameters, called parametric imaging, can locate the regional distr...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审


    authors: Shidahara M,Ikoma Y,Kershaw J,Kimura Y,Naganawa M,Watabe H

    更新日期:2007-09-01 00:00:00

  • Assessment of collimators in radium-223 imaging with channelized Hotelling observer: a simulation study.

    abstract:OBJECTIVE:Radium-223 (223Ra) is used in unsealed radionuclide therapy for metastatic bone tumors. The aim of this study is to apply a computational model observer to 223Ra planar images, and to assess the performance of collimators in 223Ra imaging. METHODS:The 223Ra planar images were created via an in-house Monte Ca...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Takahashi A,Baba S,Sasaki M

    更新日期:2018-12-01 00:00:00

  • Lesion detectability of a gamma camera based coincidence system with FDG in patients with malignant tumors: a comparison with dedicated positron emission tomography.

    abstract:OBJECTIVE:The aim of this study was to investigate the lesion detectability of a gamma camera based coincidence detector system (c-PET system) in comparison to the dedicated PET system (d-PET system), and thereby clarify the feasibility of the clinical application of this system and also describe any factors influencin...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章


    authors: Koga H,Sasaki M,Kuwabara Y,Nakagawa M,Hayashi K,Kaneko K,Chen T,Honda H

    更新日期:2004-04-01 00:00:00

  • Optimal ROI setting on the anatomically normalized I-123 FP-CIT images using high-resolution SPECT.

    abstract:OBJECTIVE:The aim of this study is to establish the optimal regions of interest (ROIs) in anatomically normalized I-123 FP-CIT SPECT images for the quantification of dopamine transporter binding. METHODS:The subjects comprised 16 normal controls and 14 Parkinsonian patients. All of the normal control subjects underwen...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章


    authors: Nonokuma M,Kuwabara Y,Hida K,Tani T,Takano K,Yoshimitsu K

    更新日期:2016-11-01 00:00:00