Quantitative analysis of myocardial ischemia by technetium-99m sestamibi exercise scintigraphy: a new method for change rate mapping.

Abstract:

:In order to quantitatively assess the extent and severity of myocardial ischemia by Tc-99m sestamibi exercise myocardial scintigraphy, we developed a new method of change rate (CR) mapping and examined its efficiency. CR was calculated to divide the counts per pixel in the stress polar map by that in the rest polar map at each corresponding pixel. The CR map showed the CR values at each pixel. To correct the differences between the stress and rest images for the dose of Tc-99m sestamibi administered, the mean counts per pixel in the stress polar map and the rest map were adjusted to the same level. Regarding the regions in which the CR value was less than 1 as ischemia, we compared the abilities of the CR map and the polar map to detect coronary artery stenosis in 5 patients with angina pectoris. The sensitivity for coronary artery stenosis was 80% in the CR map, and 40% in the polar map. The specificity for both was 75%. We concluded that the CR map was effective in assessing the extent and severity of myocardial ischemia in Tc-99m sestamibi exercise myocardial scintigraphy.

journal_name

Ann Nucl Med

authors

Nakata S,Higashino H,Kuwahara T,Tanada S,Hamamoto K

doi

10.1007/BF03165306

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

349-53

issue

4

eissn

0914-7187

issn

1864-6433

journal_volume

11

pub_type

杂志文章
  • The RECIST criteria compared to conventional response evaluation after peptide receptor radionuclide therapy in patients with neuroendocrine neoplasms.

    abstract:OBJECTIVE:The Response Evaluation Criteria In Solid Tumors (RECIST) is the most used radiological method for evaluating response after peptide receptor radionuclide therapy (PRRT) in patients with neuroendocrine tumors. This method may give too positive estimates of response in slow growing tumors as it allows a substa...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1316-2

    authors: Løitegård T,Berntzen DT,Thiis-Evensen E

    更新日期:2019-03-01 00:00:00

  • Evaluation of diagnostic abilities of Ga-SPECT for head and neck lesions.

    abstract:OBJECTIVE:Single-photon emission computed tomography (SPECT) using gallium (Ga) has been frequently used for diagnosing head and neck tumors in patients. Although the usefulness of Ga-SPECT is well known, the degree of the increase in diagnostic ability with Ga-SPECT for head and neck tumors has not been reported. We c...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0116-x

    authors: Kotani J,Kawabe J,Higashiyama S,Kawamura E,Oe A,Hayashi T,Kurooka H,Tsumoto C,Kusuki M,Yamane H,Shiomi S

    更新日期:2008-05-01 00:00:00

  • Prognosis of hypertrophic cardiomyopathy: assessment by 123I-BMIPP (beta-methyl-p-(123I)iodophenyl pentadecanoic acid) myocardial single photon emission computed tomography.

    abstract::123I-BMIPP (beta-methyl-iodophenyl pentadecanoic acid) has shown unique properties for potential use in assessing myocardial metabolism. Previous basic and clinical studies demonstrated that the disturbances of myocardial metabolism precede the occurrence of myocardial perfusion abnormalities by using 201Tl in hypertr...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03165056

    authors: Nishimura T,Nagata S,Uehara T,Morozumi T,Ishida Y,Nakata T,Iimura O,Kurata C,Wakabayashi Y,Sugihara H,Otsuki K,Wada T,Koga Y

    更新日期:1996-02-01 00:00:00

  • Evaluation of the protective effect of verapamil on reperfusion injury by 111In anticardiac myosin antibody in canine myocardial infarction.

    abstract::We quantitated the protective effect of verapamil on reperfusion injury in canine myocardial infarct using 111In-anticardiac myosin antibody and correlated to the electronmicroscopic findings. Experimental myocardial infarction was performed by one hour occlusion of the anterior descending coronary artery and followed...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164623

    authors: Chung JK,Lim SM,Lee MC,Koh CS,Lee M,Seo JW

    更新日期:1991-09-01 00:00:00

  • Comparative evaluation of scintigraphy and upper gastrointestinal tract endoscopy for detection of duodenogastric reflux.

    abstract::Duodenogastric reflux, the reflux of duodenal bile into stomach, when suspected clinically requires an objective evaluation for proper management. In this study hepatobiliary scintigraphy in 91 patients of different clinical conditions was evaluated for presence of duodenogastric reflux. Upper gastrointestinal endosco...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF03164995

    authors: Mittal BR,Ibrarullah M,Agarwal DK,Maini A,Ali W,Sikora SS,Das BK

    更新日期:1994-08-01 00:00:00

  • Usefulness of 67Ga SPECT and integrated low-dose CT scanning (SPECT/CT) in the diagnosis of cardiac sarcoidosis.

    abstract:OBJECTIVE:We performed 67Gallium (Ga) single-photon emission computed tomography (SPECT) with integrated low-dose computed tomography (CT) for the interpretation of myocardial outline to investigate the value of co-registered fusion imaging using a hybrid system (SPECT/CT) in patients with cardiac sarcoidosis. METHODS...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0064-5

    authors: Momose M,Kadoya M,Koshikawa M,Matsushita T,Yamada A

    更新日期:2007-12-01 00:00:00

  • Assessment of myocardial viability in patients with myocardial infarction using twenty-four hour thallium-201 late redistribution imaging.

    abstract:BACKGROUND:Rest thallium-201 (201Tl) myocardial perfusion imaging has been widely used for evaluation of myocardial ischemia/viability after myocardial infarction, but the ideal timing for imaging after injection to maximally estimate viability is not well established. METHODS:Thirty-six patients with myocardial infar...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985586

    authors: Yang XJ,He YM,Zhang B,Wu YW,Hui J,Jiang TB,Song JP,Liu ZH,Jiang WP

    更新日期:2006-01-01 00:00:00

  • Tumor thrombus in the inferior vena cava from colon cancer detected by 18F-FDG-PET.

    abstract::We present a case of inferior vena cava (IVC) tumor thrombus detected by fluorine- 18 fluorodeoxyglucose positron emission tomography (18F-FDG-PET). A man underwent operations for the treatment of sigmoid colon cancer at the age of 63. Because tumor markers [carcinoembryonic antigen (CEA) and CA19-9] were increased at...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0003-5

    authors: Kaida H,Ishibashi M,Kurata S,Uchida M,Hayabuchi N

    更新日期:2007-06-01 00:00:00

  • Quantification evaluation of 99mTc-MDP concentration in the lumbar spine with SPECT/CT: compare with bone mineral density.

    abstract:BACKGROUND:Despite recent technological advances allowing for quantitative single-photon emission computed tomography (SPECT), quantitative SPECT has not been widely used in the clinical practice of osteoporosis. The aim of this study is to evaluate the feasibility of quantitative bone SPECT/CT for measuring lumbar sta...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-019-01425-x

    authors: Huang K,Feng Y,Liu D,Liang W,Li L

    更新日期:2020-02-01 00:00:00

  • The role of 13N-ammonia in the differential diagnosis of gliomas and brain inflammatory lesions.

    abstract:OBJECTIVE:To investigate the utility of 13N-ammonia PET/CT imaging in the differential diagnosis of gliomas and brain inflammations. METHODS:13N-ammonia PET/CT imaging data of 77 patients with gliomas and 34 patients with brain inflammations were retrospectively analyzed. No patients received any treatment before 13N-...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1308-2

    authors: Yi C,Shi X,Zhang X,Luo G,Zhang B,Zhang X

    更新日期:2019-01-01 00:00:00

  • Correction of scattered photons in Tc-99m imaging by means of a photopeak dual-energy window acquisition.

    abstract::We are proposing a new method for correcting of scattered photons in technetium-99m (99mTc) imaging by means of photopeak dual-energy window acquisition. This method consists of the simultaneous acquisition of two images and estimation of a scatter image included in the symmetric energy window (SW) image by the differ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03178307

    authors: Kojima A,Tsuji A,Takaki Y,Tomiguchi S,Hara M,Matsumoto M,Takahashi M

    更新日期:1992-08-01 00:00:00

  • Evaluation of 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography in gastric carcinoma: relation to histological subtypes, depth of tumor invasion, and glucose transporter-1 expression.

    abstract:OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02984657

    authors: Yamada A,Oguchi K,Fukushima M,Imai Y,Kadoya M

    更新日期:2006-11-01 00:00:00

  • Comparison of exercise-rest-reinjection Tl-201 imaging and rest sublingual isosorbide dinitrate Tc-99m MIBI imaging for the assessment of myocardial viability.

    abstract:PURPOSE:Nitrate administration has been proposed to enhance the detection of myocardial viability when performing myocardial perfusion imaging. In this study, we aimed to compare Tl-201 exercise-rest-reinjection protocol with rest isosorbide dinitrate (ISDN)-Tc99m MIBI study in the same population examined for the myoc...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12149-009-0256-2

    authors: Günel SE,Akgun A

    更新日期:2009-07-01 00:00:00

  • Lesion detectability of a gamma camera based coincidence system with FDG in patients with malignant tumors: a comparison with dedicated positron emission tomography.

    abstract:OBJECTIVE:The aim of this study was to investigate the lesion detectability of a gamma camera based coincidence detector system (c-PET system) in comparison to the dedicated PET system (d-PET system), and thereby clarify the feasibility of the clinical application of this system and also describe any factors influencin...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985103

    authors: Koga H,Sasaki M,Kuwabara Y,Nakagawa M,Hayashi K,Kaneko K,Chen T,Honda H

    更新日期:2004-04-01 00:00:00

  • (99m)Tc-DTPA dynamic SPECT and CT volumetry for measuring split renal function in live kidney donors.

    abstract:OBJECTIVES:Split renal function (SRF) estimated from the posterior view of (99m)Tc-diethylenetriaminepentaacetic acid planar scintigraphy (DTPA/P) is not sufficiently accurate even after correction for kidney depth by computed tomography (CT). To obtain more accurate SRF using (99m)Tc-DTPA, dynamic SPECT method was car...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-010-0349-y

    authors: Miyazaki C,Harada H,Shuke N,Okizaki A,Miura M,Hirano T

    更新日期:2010-04-01 00:00:00

  • Fluorine-18-fluorodeoxyglucose positron emission tomography for assessment of patients with unresectable recurrent or metastatic lung cancers after CT-guided radiofrequency ablation: preliminary results.

    abstract:OBJECTIVES:We compared the diagnostic value of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) with that of computed tomography (CT) following radiofrequency ablation (RFA) of inoperable recurrent or metastatic cancers in the lung. METHODS:Twelve patients (9 males and 3 females; 5 had recurrent l...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985623

    authors: Okuma T,Okamura T,Matsuoka T,Yamamoto A,Oyama Y,Toyoshima M,Koyama K,Inoue K,Nakamura K,Inoue Y

    更新日期:2006-02-01 00:00:00

  • Luxury perfusion phenomenon in acute herpes simplex virus encephalitis.

    abstract::In a patient with acute herpes simplex virus (HSV) encephalitis, positron emission tomography (PET) demonstrated increased cerebral blood flow in the affected temporal lobe accompanied by reduction in the cerebral oxygen extraction fraction and the cerebral metabolic rate of oxygen, i.e., luxury perfusion. Follow-up P...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03165008

    authors: Tanaka M,Uesugi M,Igeta Y,Kondo S,Sun X,Hirai S

    更新日期:1995-02-01 00:00:00

  • Internal radiotherapy techniques using radiolanthanide praseodymium-142: a review of production routes, brachytherapy, unsealed source therapy.

    abstract::Radionuclides of rare earth elements are gaining importance as emerging therapeutic agents in nuclear medicine. β(-)-particle emitter 142Pr [T (1/2) = 19.12 h, E(-)β = 2.162 MeV (96.3%), Eγ = 1575 keV (3.7%)] is one of the praseodymium-141 (100% abundant) radioisotopes. Production routes and therapy aspects of 142Pr w...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-011-0505-z

    authors: Bakht MK,Sadeghi M

    更新日期:2011-10-01 00:00:00

  • Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT.

    abstract::18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevate...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-008-0139-y

    authors: Chen CJ,Yao WJ,Chou CY,Chiu NT,Lee BF,Wu PS

    更新日期:2008-07-01 00:00:00

  • Metallic artifacts caused by dental metal prostheses on PET images: a PET/CT phantom study using different PET/CT scanners.

    abstract:OBJECTIVE:The objective of this study was to investigate the effects of computed tomography (CT) artifacts caused by dental metal prostheses on positron emission tomography (PET) images. METHODS:A dental arch cast was fixed in a cylindrical water-bath phantom. A spherical phantom positioned in the vicinity of the dent...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-009-0254-4

    authors: Shimamoto H,Kakimoto N,Fujino K,Hamada S,Shimosegawa E,Murakami S,Furukawa S,Hatazawa J

    更新日期:2009-07-01 00:00:00

  • Quantifying regional cerebral blood flow with N-isopropyl-p[123I]iodoamphetamine by ring-type single-photon emission computed tomography: validity of a method to estimate early reference value by means of regional brain time-activity curve.

    abstract::A more accurate quantitative method for the measurement of regional cerebral blood flow (rCBF) with the microsphere model and N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) and ring-type single-photon emission computed tomography (SPECT) was developed. Continuous withdrawal of arterial blood was carried out for 5 minu...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03165028

    authors: Takahashi N

    更新日期:1994-11-01 00:00:00

  • A large renal pelvic diverticulum, presenting incomplete excretion during tc-99m MAG-3 scintigraphy and tracer accumulation on tc-99m DMSA scintigraphy; a case report.

    abstract::This case report illustrates the dynamic and static renal scintigraphic images of a patient with an unusual large diverticulum of the renal pelvis. The initial diagnosis by intravenous pyelography (IVP) and ultrasonographic (US) examination was a renal pelvic diverticulum of the left kidney, and the patient was referr...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02985963

    authors: Turgut B,Erselcan T,Ozdemir S,Hasbek Z,Tosun HB,Topaktas S

    更新日期:2004-12-01 00:00:00

  • Performance of beta- and high-energy gamma probes for the detection of cancer tissue in experimental surgical resection beds.

    abstract:OBJECTIVE:While high-energy gamma and beta probes have gained considerable attention due to their ability to detect cancerous lesions using (18)F-FDG in humans intraoperatively, it is unknown whether the sensitivity of such probes would allow the detection of remaining tumor tissue in the resection bed after removal of...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-011-0492-0

    authors: Garcia-Parra R,Clinthorne N,Wang L,Picchio M,Piert M

    更新日期:2011-08-01 00:00:00

  • Choline PET/CT for imaging prostate cancer: an update.

    abstract::Whole-body positron emission tomography/computed tomography (PET/CT) with [(11)C]- and [(18)F]-labeled choline derivates has emerged as a promising molecular imaging modality for the evaluation of prostate cancer. (11)C- and (18)F-choline PET/CT are used successfully for restaging prostate cancer in patients with bioc...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-013-0731-7

    authors: Kitajima K,Murphy RC,Nathan MA

    更新日期:2013-08-01 00:00:00

  • False-positive and true-negative hilar and mediastinal lymph nodes on FDG-PET--radiological-pathological correlation.

    abstract:OBJECTIVE:To compare histological findings of FDG-PET false-positive and true-negative hilar and mediastinal lymph nodes. METHODS:Sixty-seven lymphnode areas in 11 patients who were diagnosed to have N3 lymph nodes by FDG-PET and underwent surgery were histologically examined, and the histopathological findings in fal...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985610

    authors: Shiraki N,Hara M,Ogino H,Shibamoto Y,Iida A,Tamaki T,Murase T,Eimoto T

    更新日期:2004-02-01 00:00:00

  • Prediction of all-cause death using (11)C-hydroxyephedrine positron emission tomography in Japanese patients with left ventricular dysfunction.

    abstract:OBJECTIVES:The aim of this study was to determine whether (11)C-hydroxyephedrine ((11)C-HED) can predict adverse events including all-cause death in Japanese patients with left ventricular (LV) dysfunction. BACKGROUND:Although (11)C-HED PET has been used to assess cardiac sympathetic innervation in various disease con...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-016-1081-z

    authors: Fujita W,Matsunari I,Aoki H,Nekolla SG,Kajinami K

    更新日期:2016-08-01 00:00:00

  • Radioactive synthesis of tau PET imaging agent 18F-AV-1451 and its role in monitoring the progression of Alzheimer's disease and supporting differential diagnosis.

    abstract::Alzheimer's disease (AD) is on the rise all over the world, and brings with it great challenges to medical care and heavy burdens to family and society. Accurate diagnosis and differential diagnosis are of great importance. Tau positron emission tomography (PET) might offer novel insights and be of great assistance in...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-020-01566-4

    authors: Zhang W,Xu S,Yu H,Li X,Jin Z,Li Y,He Z

    更新日期:2021-01-18 00:00:00

  • The utility of FDG-PET/CT as an effective tool for detecting recurrent colorectal cancer regardless of serum CEA levels.

    abstract:PURPOSE:Tumor recurrence of colorectal cancers (CRC) is generally followed up by analyses of the serum carcinoembryonic antigen (CEA) levels. However, recent evidence suggests that tumor recurrence can also be visualized by 18F-fluoro-deoxyglucose emission tomography/computed tomography (FDG-PET/CT) in patients with no...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-012-0609-0

    authors: Sanli Y,Kuyumcu S,Ozkan ZG,Kilic L,Balik E,Turkmen C,Has D,Isik G,Asoglu O,Kapran Y,Adalet I

    更新日期:2012-08-01 00:00:00

  • Assessment of absolute Tc-99m tetrofosmin retention in the myocardium as an index of myocardial blood flow and coronary flow reserve by gated-SPECT/CT: a feasibility study.

    abstract:OBJECTIVE:Estimation of myocardial blood flow (MBF) and coronary flow reserve (CFR) by SPECT myocardial perfusion imaging (MPI) remains challenging. Our aim was to approximate MBF and CFR by quantifying the absolute Tc-99m tetrofosmin retention in the myocardium via gated-SPECT/CT MPI. METHODS:Tracer retention was cal...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12149-015-0982-6

    authors: Apostolopoulos DJ,Kaspiri A,Spyridonidis T,Patsouras N,Savvopoulos CA,Davlouros P,Vassilakos PJ,Alexopoulos D

    更新日期:2015-08-01 00:00:00

  • Discontinuation of metformin to prevent metformin-induced high colonic FDG uptake: is 48 h sufficient?

    abstract:OBJECTIVE:In this retrospective, single-center observational study, we investigated whether discontinuing metformin for at least 48 h prevents metformin-induced [18F]fluorodeoxyglucose (FDG) uptake in all segments of the colon. METHODS:Patients with type 2 diabetes who were using metformin before undergoing an FDG PET...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-020-01509-z

    authors: Schreuder N,Klarenbeek H,Vendel BN,Jager PL,Kosterink JGW,van Puijenbroek EP

    更新日期:2020-11-01 00:00:00