Assessment of myocardial viability in patients with myocardial infarction using twenty-four hour thallium-201 late redistribution imaging.

Abstract:

BACKGROUND:Rest thallium-201 (201Tl) myocardial perfusion imaging has been widely used for evaluation of myocardial ischemia/viability after myocardial infarction, but the ideal timing for imaging after injection to maximally estimate viability is not well established. METHODS:Thirty-six patients with myocardial infarction underwent the initial, 3 h, and 24 h redistribution imaging after intravenous injection of 148-185 MBq 201Tl. The initial and 3 h images, the initial and 24 h images, and the 3 and 24 h images were compared double-blinded. RESULTS:Out of the 184 abnormal segments based on the initial imaging, 56 (30%) segments improved by at least 1 grade on the 3 h imaging while 78 (42%) segments improved by at least 1 grade on the 24 h imaging. The 24 h late imaging detected more viable myocardium than the 3 h imaging did, with a significant difference (chi2= 5.680, p = 0.017). There were 158 abnormal segments on the 3 h imaging, with average 28% (44) segments improved by at least 1 grade on the 24 h imaging. There were 128 initial abnormal segments with no improvement on the 3 h imaging. Out of these segments, the 24 h late redistribution imaging detected additional redistribution in 26 segments, taking up 20%. CONCLUSIONS:Twenty-four hour late 201Tl imaging will demonstrated additional redistribution in patients who have incompletely reversible defects on early redistribution imaging at 3h.

journal_name

Ann Nucl Med

authors

Yang XJ,He YM,Zhang B,Wu YW,Hui J,Jiang TB,Song JP,Liu ZH,Jiang WP

doi

10.1007/BF02985586

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

23-8

issue

1

eissn

0914-7187

issn

1864-6433

journal_volume

20

pub_type

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