Luxury perfusion phenomenon in acute herpes simplex virus encephalitis.

Abstract:

:In a patient with acute herpes simplex virus (HSV) encephalitis, positron emission tomography (PET) demonstrated increased cerebral blood flow in the affected temporal lobe accompanied by reduction in the cerebral oxygen extraction fraction and the cerebral metabolic rate of oxygen, i.e., luxury perfusion. Follow-up PET studies showed reduction in cerebral perfusion until it was more closely coupled with oxygen metabolism after the resolution of the acute inflammation. These findings support previous single photon emission computed tomographic data and provide a pathophysiological background for the occurrence of hyperperfusion in HSV encephalitis. This is an interesting example of the luxury perfusion phenomenon occurring in a disease other than cerebral ischemia.

journal_name

Ann Nucl Med

authors

Tanaka M,Uesugi M,Igeta Y,Kondo S,Sun X,Hirai S

doi

10.1007/BF03165008

subject

Has Abstract

pub_date

1995-02-01 00:00:00

pages

43-5

issue

1

eissn

0914-7187

issn

1864-6433

journal_volume

9

pub_type

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