Abstract：
:Classical descriptions of the pathology of amebiasis portray the parasite as the cause of tissue damage and destruction, and in recent years a number of amebic molecules have been identified as virulence factors. In this review we describe a series of experiments that suggest a more complex host-parasite relation, at least during the early stages of acute experimental amebic liver abscess in hamsters. The problems of extrapolating experiments in vitro to explain observations in vivo are discussed. The role of amebic cysteine proteases is examined and evidence presented to suggest that they are primarily related not to tissue damage but to amebic survival, which is required for the progression of the lesion. Inflammation is shown to be not only the major cause of tissue damage but also an absolute requirement for amebic survival in the liver, whereas complement and ischemia are not involved in the disappearance of the parasite in the absence of inflammation.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Pérez-Tamayo R,Montfort I,García AO,Ramos E,Ostria CBdoi
10.1016/j.arcmed.2005.10.007subject
Has Abstractpub_date
2006-02-01 00:00:00pages
203-9issue
2eissn
0188-4409issn
1873-5487pii
S0188-4409(05)00373-5journal_volume
37pub_type
杂志文章,评审abstract：BACKGROUND:Studies in platelet of 5-HT uptake transporters have been performed using binding assay methodology designed for ligand-receptor interactions; however, uptake transporters present requirements that may question the validity of these particular binding assays. METHODS:To explore methodologic aspects that may...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2003.03.001
更新日期：2003-09-01 00:00:00
abstract：:Thanks to the results of the multiple completed and ongoing genome sequencing projects and to the newly available recombination-based cloning techniques, it is now possible to build gene repositories with no precedent in their composition, formatting, and potential. This new type of gene repository is necessary to add...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/s0188-4409(02)00372-7
更新日期：2002-07-01 00:00:00
abstract：:In recent years, the gut microbiota has been of great interest due to its role in maintaining health and its association with the development of different diseases such as obesity and diabetes. The objective of the present review is to show the main functions of the gut microbiota, the role in the degradation of compl...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2019.09.004
更新日期：2019-07-01 00:00:00
abstract：:The intestinal microbiota comprise an important organ that plays a vital role in host digestion, development, energy maintenance, hemostasis, and immunity. Disruption of the gut microbial community due to diet, lifestyle, or antibiotic exposure increases susceptibility to chronic infection and disease. Fecal microbiot...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2017.11.006
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:The diuretic response has been shown to be a robust independent marker of cardiovascular outcomes in acute heart failure (ADHF) patients. The objectives of this clinical research, will aim are to: a) include diuresis in the formula for diuretic response (R-to-D); b) add to R-to-D the value of a pre-discharge...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2018.08.007
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) is found to play important roles in acute myocardial infarction (AMI). Ventricular arrhythmias arising from AMI are leading causes of sudden cardiac death (SCD). We sought to clarify the effect of TNF-alpha early expression on ventricular arrhythmias in rats with AMI a...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2007.10.004
更新日期：2008-04-01 00:00:00
abstract：:Hué, a city of about 300,000 inhabitants in Central Vietnam, is known as a "hot spot" for diseases caused by Entamoeba histolytica and in particular for amebic liver abscess (ALA), thus representing an excellent site for studies on the epidemiology and treatment of E. histolytica infections. Accordingly, during the la...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2005.10.001
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Interleukin-19 (IL-19) has been shown to be involved in coronary artery diseases and atherosclerosis, while its expression in myocardial infarction is poorly understood. In this study, the dynamic increase in circulating IL-19 in acute ST-segment elevation myocardial infarction (STEMI) patients was detected....
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.01.007
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Growth deficits are common in children with sickle cell disease. Few prospective studies are available and the pathophysiologic basis for the impaired growth is not clearly understood. Our objectives were to collect data on anthropomorphic measurements of children with sickle cell disease prospectively follo...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/s0188-4409(01)00360-5
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:The human multidrug-resistant gene (MDR1) encodes P-glycoprotein (Pgp), a membrane-bound efflux transporter conferring resistance to a number of natural cytotoxic drugs and potentially toxic xenobiotics. Single-nucleotide polymorphisms (SNPs) in MDR1 gene are associated with phenotypic variation in Pgp expre...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2007.02.005
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Patients suffering from hypothyroidism tend to develop diastolic hypertension. 5-Hydroxytryptamine (5-HT) is an amine that contributes to the maintenance of the blood pressure through central and peripheral 5-HT receptors. Curiously, the hypothyroidism alters the density of the 5-HT receptors in rodent brain...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.03.013
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND AND AIM:Oxalobacter formigenes is an intestinal bacterium that utilizes oxalate as the only source of energy. It has been suggested that the lack of colonization with this organism may be a risk factor for calcium oxalate urolithiasis. Because this problem was not investigated in pediatric stone formers, we ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2009.05.004
更新日期：2009-07-01 00:00:00
abstract：:Metabolic syndrome (MetS) should be considered a clinical entity when its different symptoms share a common etiology: obesity/insulin resistance as a result of a multi-organ dysfunction. The main interest in treating MetS as a clinical entity is that the addition of its components drastically increases the risk of ath...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2015.05.007
更新日期：2015-07-01 00:00:00
abstract：:Hepatitis C represents more than 35% of liver transplant candidates worldwide. Meanwhile, hepatitis B continues to be an important cause of end-stage liver disease and hepatocellular carcinoma in Asia and Africa. Recurrent viral liver disease is a significant event after liver transplantation and continues to be one o...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2006.09.003
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Bacteremia is a common serious manifestation of disease in the intensive care unit (ICU), which requires quick and accurate determinations of pathogens to select the appropriate antibiotic treatment. To overcome the shortcomings of traditional bacterial culture (BC), we have adapted next-generation ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2016.08.004
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) has been shown to improve the clinical status and survival in congestive heart failure (CHF) patients, but little is known about its influence on neurohormonal profile. METHODS:Heart failure patients treated with CRT for moderate/severe heart failure were studied with...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章
doi：10.1016/j.arcmed.2008.07.004
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:We undertook this study to analyze serum and platelet gamma-glutamyltransferase (GGT) activity and total antioxidant status (TAS) concentration during the course of pneumonia and to compare them between patients with normal platelet count and those who developed reactive thrombocytosis. METHODS:Platelet cou...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2007.01.005
更新日期：2007-05-01 00:00:00
abstract：:In Mexico, hypercholesterolemia has become a major public health problem particularly in the states of the north of the country and in Mexico City, where a prevalence of 20% has been reported. Schemes of treatment have now been reinforced by the appearance of new cholesterol reducing drugs. The objective of the study ...
journal_title：Archives of medical research
pub_type： 临床试验,杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Idiopathic ventricular tachycardia is a well described syndrome of both left and right ventricular origin. This study reports the feasibility and efficacy of catheter ablation in this entity. Fourteen patients (mean age 30 +/- 10 years of age) and six patients (mean age 51 +/- 9 years of age) underwent endocardial cat...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND AND AIMS:Further cases of novel influenza A (H1N1) outbreak are expected in the coming months. Vaccination has been proven to be essential to control a pandemic of influenza; therefore, considerable efforts and resources have been devoted to develop a vaccine against the influenza A (H1N1) virus. With the cu...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2010.01.004
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Although Leishmania virulence may be modulated by environmental and genetic factors of their mammalian hosts and sand fly vectors, molecular determinants of Leishmania sp. are the key elements. This work evidences that Leishmania amazonensis axenic amastigotes produce comparatively more NO than infective pro...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2005.07.011
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Previous studies demonstrated that (99m)Tc-labeled-ubiquicidin 29-41 ((99m)Tc-UBI 29-41) imaging is an accurate method for detection of bacterial infections. This study was conducted to evaluate the clinical use of (99m)Tc-UBI 29-41 for detection of mediastinitis after cardiac surgery. METHODS:Thirteen pati...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2008.09.002
更新日期：2008-11-01 00:00:00
abstract：AIMS:To explore the effect of salvianolic acid B (Sal B) on regulation of SIRT3/FOXO1 signaling pathway in rats with non-alcoholic steatohepatitis (NASH). METHODS:Sixty Sprague Dawley (SD) rats were randomly divided into control, model and treatment groups. After 12 weeks of successful model establishment with high fa...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2017.11.016
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND AND AIMS:The etiology of atherosclerosis is multifactorial. Genetic and environmental factors are involved in the development of atherosclerosis. Human arylamine N-acetyltransferase 2 (NAT2) is an important metabolizing enzyme that exhibits genetic polymorphisms and modifies individual response and/or toxici...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2010.03.008
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Vascular endothelial growth factor (VEGF), an important regulator of angiogenesis and vascular permeability, is involved in various steps of many malignancies. Gene polymorphisms within the gene encoding VEGF have been shown to be independently associated with an adverse outcome in various malignancies inclu...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2009.07.011
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflammatory response. METHODS:This study consisted of 136 Iranian patients with cardiovascular disease (65 MetS-affected and 71 MetS un-affected individuals) in the selengene study. Expression o...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.05.005
更新日期：2020-08-01 00:00:00
abstract：:Clinical research in Internal Medicine has provided many scientific advances during the past few years. However, the newly generated information overrides the time available to read all of the medical literature regarding advances in Internal Medicine. The goal of this review is to summarize some of the most relevant ...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Wind instrument playing requires a strenuous respiratory activity. Previous studies investigating effect of wind instrument playing on pulmonary function are equivocal. METHODS:In the present study, 34 male, non-smoker wind players in a military band were compared with 44 healthy non-smoker males by pulmona...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2005.09.015
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND AND AIMS:Intestinal microbiota and soluble dietary fiber play an important role in intestinal microecology, which is closely related to gut motility. Regulating intestinal microecology comprised of fecal microbiota transplantation (FMT) or fiber supplementation is becoming a novel therapy for functional gast...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2016.06.005
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Angiotensin converting enzyme (ACE) inhibitors and angiotensin II AT1-receptor antagonists prolong survival in experimental postischemic heart failure (CHF) in rats. The aim of this study was to investigate whether potential beneficial effects of early and long-term therapy with low doses of captopril or los...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/S0188-4409(03)00076-6
更新日期：2003-09-01 00:00:00
