Abstract:
:A 29-year-old woman presented to the emergency department with exhaustion, fatigue, and abdominal pain. She reported having received a diagnosis of bulimia nervosa 10 years before. On examination, she had a marked pallor and was severely malnourished. Laboratory analysis revealed a dramatically low hemoglobin level of 1.7 g/dL (ref: 11.5-15.8 g/dL). Serum iron was quantified as 1.4 micromol/L (ref: 7-26 micromol/L), ferritin as 5 ng/mL (ref: 10-120 ng/mL), and the level of serum transferrin as 212 mg/dL (ref: 200-360 mg/dL). A duodenal biopsy revealed villous atrophy in the mucosal layer indicative for celiac disease. This diagnosis was confirmed by serum levels of endomysial antibodies, tissue transglutaminase antibody, and antigliadin antibodies. The newly diagnosed gluten-sensitive enteropathy is likely to be in part responsible for the severe symptoms reported. The extent of hemoglobin decline in combination with an astonishing lack of critical symptoms seen in this patient is a rarity. We conclude that anorectic patients with severe anemia and malnutrition should be evaluated for the presence of additional somatic conditions.
journal_name
Int J Hematoljournal_title
International journal of hematologyauthors
Jost PJ,Stengel SM,Huber W,Sarbia M,Peschel C,Duyster Jdoi
10.1532/IJH97.E0505subject
Has Abstractpub_date
2005-11-01 00:00:00pages
310-1issue
4eissn
0925-5710issn
1865-3774pii
42QK8EUNH5WRTPABjournal_volume
82pub_type
杂志文章abstract::While anti-cancer chemotherapy has improved the survival of patients with hematologic malignancies, it has also exposed such patients to the risk of life-threatening infection due to neutropenia. In intensive chemotherapy for leukemia, invasive aspergillosis resulting in death is infrequently observed. In such cases, ...
journal_title:International journal of hematology
pub_type: 杂志文章
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journal_title:International journal of hematology
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journal_title:International journal of hematology
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journal_title:International journal of hematology
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journal_title:International journal of hematology
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pub_type: 杂志文章,meta分析,评审
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更新日期:2010-11-01 00:00:00
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journal_title:International journal of hematology
pub_type: 杂志文章,多中心研究
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更新日期:2006-12-01 00:00:00
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journal_title:International journal of hematology
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pub_type: 临床试验,杂志文章
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journal_title:International journal of hematology
pub_type: 杂志文章
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journal_title:International journal of hematology
pub_type: 杂志文章
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journal_title:International journal of hematology
pub_type: 杂志文章,评审
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