当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF HEMATOLOGY期刊下所有文献 > Predictors of anxiety and depression in Egyptian thalassemic patients: a single center study.

Predictors of anxiety and depression in Egyptian thalassemic patients: a single center study.

Abstract：

:Thalassemic patients are vulnerable to emotional and behavioral problems. Each patient age group exhibits problems unique to that stage of development, and although up to 80 % of thalassemic patients are likely to have psychological disorders, e.g., anxiety and depression, predictors of these disorders remain poorly understood. The present study was designed to assess the prevalence of anxiety and depression in a sample of Egyptian thalassemic patients and to identify predictors of these psychiatric disorders. A case-control study was conducted in 218 thalassemic patients, with 244 healthy subjects as a control. All patients and control subjects were subjected to thorough evaluation of medical history and clinical examination, and examined by a psychiatrist using the clinician version of the structured clinical interview for DSM-IV (SCID-CV), hospital anxiety and depression scale and Coopersmith self-esteem inventory. Abnormal and borderline anxieties were reported by 36.7 and 20.6 % of thalassemic patients, respectively, while abnormal and borderline depressions were reported by 32.1 and 16.1 % of patients, respectively. Hospitalization, low self-esteem, diabetes mellitus and heart failure were independent predictors of anxiety. The independent predictors of depression were heart failure, hospitalization, diabetes mellitus, short stature and delayed puberty. Thalassemic patients were more vulnerable to anxiety and depression, indicating that screening and management for such psychiatric disorders should be considered in treating all such patients.

journal_name

Int J Hematol

journal_title

International journal of hematology

authors

Yahia S,El-Hadidy MA,El-Gilany AH,Anwar R,Darwish A,Mansour AK

doi

10.1007/s12185-013-1322-z

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

604-9

issue

5

eissn

0925-5710

issn

1865-3774

journal_volume

97

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF HEMATOLOGY文献大全
  • Gene therapy of X-linked severe combined immunodeficiency.

    abstract：:Severe combined immunodeficiency (SCID) conditions appear to be the best possible candidates for a gene therapy approach. Transgene expression by lymphocyte precursors should confer to these cells a selective growth advantage that gives rise to long-lived T-lymphocytes. This rationale was used as a basis for a clinica...

    journal_title：International journal of hematology

    pub_type： 杂志文章,评审

    doi：10.1007/BF02982686

    authors： Hacein-Bey-Abina S,Fischer A,Cavazzana-Calvo M

    更新日期：2002-11-01 00:00:00

  • Treatment patterns and clinical outcomes in patients with chronic immune thrombocytopenia (ITP) switched to eltrombopag or romiplostim.

    abstract：:This observational study aimed to assess real-world treatment patterns and clinical outcomes for patients with chronic immune thrombocytopenia (ITP) currently being treated with eltrombopag or romiplostim after switching from corticosteroids, rituximab, or the alternate thrombopoietin receptor agonist (TPO-RA). The st...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-014-1731-7

    authors： Kuter DJ,Macahilig C,Grotzinger KM,Poston SA,Wang PF,Dawson KL,Ward M

    更新日期：2015-03-01 00:00:00

  • JAK2 46/1 haplotype is associated with JAK2 V617F-positive myeloproliferative neoplasms in Japanese patients.

    abstract：:Myeloproliferative neoplasms (MPNs) constitute a group of phenotypically diverse chronic myeloid malignancies, characterized by clonal hematopoiesis and excessive production of terminally differentiated myeloid blood cells. The MPNs include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibro...

    journal_title：International journal of hematology

    pub_type： 临床试验,杂志文章

    doi：10.1007/s12185-013-1295-y

    authors： Tanaka M,Yujiri T,Ito S,Okayama N,Takahashi T,Shinohara K,Azuno Y,Nawata R,Hinoda Y,Tanizawa Y

    更新日期：2013-03-01 00:00:00

  • Antithrombotic effects of tetramethylpyrazine in in vivo experiments.

    abstract：:In this study, tetramethylpyrazine (TMPZ) was effective in reducing the mortality of ADP-induced acute pulmonary thromboembolism in mice when administered intravenously at doses of 40 and 80 microg/g. In addition, intravenous injection of TMPZ (10 microg/g) significantly prolonged the bleeding time by approximately 1....

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/BF02981969

    authors： Sheu JR,Hsiao G,Lee YM,Yen MH

    更新日期：2001-04-01 00:00:00

  • Efficacy and safety of a 4-factor prothrombin complex concentrate for rapid vitamin K antagonist reversal in Japanese patients presenting with major bleeding or requiring urgent surgical or invasive procedures: a prospective, open-label, single-arm phase

    abstract：:Rapid vitamin K antagonist (VKA) reversal is required in patients experiencing major bleeding or requiring urgent surgery. Four-factor prothrombin complex concentrate (4F-PCC; Beriplex®/Kcentra®) was shown in two large randomized controlled, international phase 3b trials to be an effective alternative to plasma for ur...

    journal_title：International journal of hematology

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s12185-017-2311-4

    authors： Kushimoto S,Fukuoka T,Kimura A,Toyoda K,Brainsky A,Harman A,Chung T,Yasaka M

    更新日期：2017-12-01 00:00:00

  • Results of treatment with CMA, a low intermediate regimen, in endemic Burkitt lymphomas in sub-Saharian Africa: experience of Côte d'Ivoire.

    abstract：:African Burkitt lymphomas (BL) are highly aggressive lymphomas mainly affecting children and young adults in Africa. This lymphoma was marked by its high sensitivity to chemotherapy in comparison to Sporadic Burkitt lymphoma. In this study, we evaluated the treatment response and survival of patients with CMA protocol...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-010-0591-z

    authors： Koffi GK,Tolo A,Nanho DC,N'dathz E,Kouassi MY,N'Diaye FD,Kouakou B,Meité N,Ayemou R,Sekongo M,Kouehion P,Meité M,Tea ND,Sangaré A,Sanogo I

    更新日期：2010-06-01 00:00:00

  • Calcineurin inhibitor-induced irreversible neuropathic pain after allogeneic hematopoietic stem cell transplantation.

    abstract：:The calcineurin inhibitors (CIs) cyclosporine A and tacrolimus are essential for graft-versus-host disease prophylaxis but are associated with adverse effects, including neurotoxicity. We report a case of irreversible CI-induced neuropathic pain following allogeneic hematopoietic stem cell transplantation. The patient...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1532/IJH97.05154

    authors： Fujii N,Ikeda K,Koyama M,Aoyama K,Masunari T,Kondo E,Matsuzaki T,Mizobuchi S,Hiraki A,Teshima T,Shinagawa K,Ishimaru F,Tanimoto M

    更新日期：2006-06-01 00:00:00

  • Molecular basis of beta-thalassemia minor in Taiwan.

    abstract：:The mutations producing beta-thalassemia minor in 227 Taiwanese were studied using the method of naturally and amplified created restriction sites. beta-Thalassemia minor was caused by one beta-globin gene mutation in most of the cases (225/227); only a few cases were caused by two gene mutation (2/227). The most comm...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：

    authors： Chang JG,Lin CP,Liu TC,Chiou SS,Chen PH,Lee LS,Chen TP

    更新日期：1994-06-01 00:00:00

  • Successful graft-versus-leukemia effect of second bone marrow transplantation on relapsed leukemia cutis that was refractory to intensive chemotherapy and donor lymphocyte transfusions in a patient with acute monocytic leukemia.

    abstract：:We report a patient with acute monocytic leukemia (AMoL; M5) who received a second bone marrow transplantation (BMT) with graft-versus-leukemia (GVL) effect on relapsed leukemia cutis, which had been refractory to intensive chemotherapy and donor lymphocyte transfusions (DLTs). A 21-year-old woman was diagnosed with A...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：

    authors： Ashida T,Kawanishi K,Ariyama T,Hamasaki H,Maeda Y,Tsubaki K,Kanamaru A

    更新日期：2000-06-01 00:00:00

  • Primary mediastinal large B-cell lymphoma in Japanese children and adolescents.

    abstract：:This is the first case series to describe primary mediastinal large B-cell lymphoma (PMLBL) patients in children and adolescents in Asia. We retrospectively identified 17 PMLBL patients diagnosed between 1991 and 2014; in seven of these cases, the diagnosis was confirmed by central review, representing 1.0% of all NHL...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-016-2147-3

    authors： Osumi T,Tanaka F,Mori T,Fukano R,Tsurusawa M,Oshima K,Nakazawa A,Kobayashi R

    更新日期：2017-04-01 00:00:00

  • Plasma level of lipopolysaccharide-binding protein is indicative of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation.

    abstract：:Acute graft-versus-host disease (aGVHD) is the major cause of non-relapse mortality following allogeneic hematopoietic stem cell transplantation. To date, there are no consensus specific plasma biomarkers for aGVHD. We recently identified several candidates differentially expressed in aGVHD patients. Here, we have val...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-012-1076-z

    authors： Ye H,Lv M,Zhao X,Zhao X,Huang X

    更新日期：2012-06-01 00:00:00

  • Extranodal multifocal Rosai-Dorfman disease: response to 2-chlorodeoxyadenosine treatment.

    abstract：:Rosai-Dorfman disease (RDD) or "sinus histiocytosis with massive lymphadenopathy" is a rare lymphoproliferative disorder of unknown etiology. The disease usually presents with painless lymphadenopathy with occasional extranodal involvement in various organs. We report a case of a 36-year-old man with a history of non-...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-008-0192-2

    authors： Konca C,Özkurt ZN,Deger M,Akı Z,Yağcı M

    更新日期：2009-01-01 00:00:00

  • Biology of normal and acute myeloid leukemia stem cells.

    abstract：:The substantial understanding that has been gained over the past 5 decades of the biology of blood formation is largely due to the development of functional quantitative assays for cells at all stages of differentiation, from multipotential stem cells to mature cells. The majority of studies have involved the mouse be...

    journal_title：International journal of hematology

    pub_type： 杂志文章,评审

    doi：10.1532/IJH97.05144

    authors： Dick JE,Lapidot T

    更新日期：2005-12-01 00:00:00

  • Association between OGG1 S326C CC genotype and elevated relapse risk in acute myeloid leukemia.

    abstract：:Recent studies have shown that tumors of relapsed acute myeloid leukemia (AML) present additional genetic mutations compared to the primary tumors. The base excision repair (BER) pathway corrects oxidatively damaged mutagenic bases and plays an important role in maintaining genetic stability. The purpose of the presen...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-018-2464-9

    authors： Gotoh N,Saitoh T,Takahashi N,Kasamatsu T,Minato Y,Lobna A,Oda T,Hoshino T,Sakura T,Shimizu H,Takizawa M,Handa H,Yokohama A,Tsukamoto N,Murakami H

    更新日期：2018-09-01 00:00:00

  • HHV8-positive, HIV-negative multicentric Castleman's disease: early and sustained complete remission with rituximab therapy without reactivation of Kaposi sarcoma.

    abstract：:Multicentric Castleman's disease (MCD) is a rare lymphoproliferative disorder with systemic symptoms and poor prognosis and is characterized by an abnormal proliferation of polyclonal plasmablasts in the mantle zone of B-cell follicles. The disease is found primarily in chronic HIV carriers and is usually strictly ass...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-009-0418-y

    authors： Nicoli P,Familiari U,Bosa M,Allice T,Mete F,Morotti A,Cilloni D,Saglio G,Guerrasio A

    更新日期：2009-10-01 00:00:00

  • Reversible acceleration of disease progression following cyclosporin A treatment in a patient with myelodysplastic syndrome.

    abstract：:A 38-year-old Japanese man with myelodysplastic syndrome (MDS), whose bone marrow smears demonstrated hypercellularity, was treated with oral cyclosporin A (CsA) therapy. During the course of this therapy, the numbers of peripheral blood and bone marrow blasts increased and the level of serum lactate dehydrogenase inc...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/BF02982046

    authors： Itoh M,Yago K,Shimada H,Tohyama K

    更新日期：2002-04-01 00:00:00

  • Promoter hypermethylation of the DNA-repair gene O6-methylguanine-DNA methyltransferase and p53 mutation in diffuse large B-cell lymphoma.

    abstract：:The gene for the DNA-repair enzyme O6-methylguanine-DNA methyltransferase (MGMT), which is closely related with cellular sensitivity to alkylating agents, is inactivated by promoter hypermethylation in several human cancers, including malignant lymphoma. Promoter hypermethylation of the MGMT gene is a favorable progno...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1532/IJH97.06087

    authors： Hiraga J,Kinoshita T,Ohno T,Mori N,Ohashi H,Fukami S,Noda A,Ichikawa A,Naoe T

    更新日期：2006-10-01 00:00:00

  • In vitro development of hematopoietic system from mouse embryonic stem cells: a new approach for embryonic hematopoiesis.

    abstract：:We developed an efficient differentiation induction system (OP9 system) from mouse embryonic stem (ES) cell to blood cells by coculture on a novel stromal cell line, OP9. This stromal cell line does not produce functional macrophage colony-stimulating factor (M-CSF) and presumably the deficiency of M-CSF production of...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1016/s0925-5710(96)00531-2

    authors： Nakano T

    更新日期：1996-12-01 00:00:00

  • Reduced-intensity conditioning regimen with low-dose ATG-F for unrelated bone marrow transplant is associated with lower non-relapse mortality than a regimen with low-dose TBI: a single-center retrospective analysis of 103 cases.

    abstract：:Although anti-T lymphocyte globulin-Fresenius (ATG-F) is commonly used as prophylaxis for graft-versus-host disease (GVHD), the appropriate dosage of ATG-F in the setting of a reduced-intensity conditioning (RIC) regimen has not been determined. In the present study, we retrospectively analyzed the clinical outcomes o...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-013-1449-y

    authors： Fuji S,Ueno N,Hiramoto N,Asakura Y,Yakushijin K,Kamiyama Y,Kurosawa S,Kim SW,Heike Y,Yamashita T,Fukuda T

    更新日期：2013-11-01 00:00:00

  • CD64 surface expression on neutrophils and monocytes is significantly up-regulated after stimulation with granulocyte colony-stimulating factor during CHOP chemotherapy for patients with non-Hodgkin's lymphoma.

    abstract：:The present study was performed to examine whether the expression of CD64 Fc gamma receptor type I (FcgammaRI) on both neutrophils and monocytes can be modulated by multiple daily administrations of granulocyte colony-stimulating factor (G-CSF) to patients with non-Hodgkin's lymphoma in neutropenia caused by CHOP (cyc...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/BF02983535

    authors： Kakinoki Y,Kubota H,Yamamoto Y

    更新日期：2004-01-01 00:00:00

  • Molecular analysis of the novel L243R mutation in STXBP2 reveals impairment of degranulation activity.

    abstract：:The presence of mutations in PRF1, UNC13D, STX11 and STXBP2 genes in homozygosis or compound heterozygosis results in immune deregulation. Most such cases lead to clinical manifestations of haemophagocytic lymphohistiocytosis (HLH). In the present study, we analyzed degranulation and cytotoxicity in a pediatric patien...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-019-02796-7

    authors： Viñas-Giménez L,Donadeu L,Alsina L,Rincón R,de la Campa EÁ,Esteve-Sole A,Català A,Colobran R,de la Cruz X,Sayós J,Martínez-Gallo M

    更新日期：2020-03-01 00:00:00

  • Successful unrelated bone marrow transplantation for a human immunodeficiency virus type-1-seropositive acute myelogenous leukemia patient following HAART.

    abstract：:The availability of highly active anti-retroviral therapy (HAART) has greatly improved the outcome of human immunodeficiency virus type-1 (HIV-1) infection and disease. We report here on a case of an HIV-1-seropositive patient with acute myelogenous leukemia who underwent a successful allogeneic unrelated bone marrow ...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-009-0467-2

    authors： Oka Y,Tashiro H,Mizutani-Noguchi M,Koga I,Sugao T,Shirasaki R,Miura T,Akiyama N,Kawasugi K,Fujimori S,Shirafuji N

    更新日期：2010-01-01 00:00:00

  • Systemic HD-MTX for CNS prophylaxis in high-risk DLBCL patients: a prospectively collected, single-center cohort analysis.

    abstract：:We evaluated the efficacy of systemic high-dose methotrexate (HD-MTX) for CNS prophylaxis in a prospectively recruited cohort of DLBCL patients at high risk of CNS relapse. High-risk CNS relapse was defined as the involvement of ≥ 2 extranodal sites with elevated lactate dehydrogenase (LDH); CNS international prognost...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-019-02653-7

    authors： Lee K,Yoon DH,Hong JY,Kim S,Lee K,Kang EH,Huh J,Park CS,Lee SW,Suh C

    更新日期：2019-07-01 00:00:00

  • Pediatric post-transplant diffuse large B cell lymphoma after cardiac transplantation.

    abstract：:Post-transplant lymphoproliferative disorders (PTLDs) occur in 3.5-9% of patients after pediatric cardiac transplantation. Caution is needed when treating patients with PTLD because of the risk of allograft rejection frequently caused by withdrawal of immunosuppression. In this report, we describe a 47-month-old boy w...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-008-0250-9

    authors： Kusuki S,Hashii Y,Fukushima N,Takizawa S,Tokimasa S,Kogaki S,Ohta H,Tsuda E,Nakagawa A,Ozono K

    更新日期：2009-03-01 00:00:00

  • Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 expression in hematopoietic cells.

    abstract：:Internal tandem duplication in the FLT3 gene (FLT3/ITD), which is found in patients with acute myeloid leukemia (AML), causes resistance to FLT3 inhibitors. We found that RUNX1, a transcription factor that regulates normal hematopoiesis, is up-regulated in patients with FLT3/ITD(+) AML. While RUNX1 can function as a t...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-015-1908-8

    authors： Hirade T,Abe M,Onishi C,Taketani T,Yamaguchi S,Fukuda S

    更新日期：2016-01-01 00:00:00

  • NOTCH and NF-κB interplay in chronic lymphocytic leukemia is independent of genetic lesion.

    abstract：:The NOTCH and nuclear factor kappa B (NF-κB) pathways are both constitutively activated in Chronic Lymphocytic Leukemia (CLL). We first described the NOTCH1 PEST domain mutation in a CLL subgroup, but the activation of the NOTCH pathway in NOTCH1-unmutated cases remains unexplained. Here, we investigated whether genet...

    journal_title：International journal of hematology

    pub_type： 临床试验,杂志文章

    doi：10.1007/s12185-013-1368-y

    authors： Baldoni S,Sportoletti P,Del Papa B,Aureli P,Dorillo E,Rosati E,Ciurnelli R,Marconi P,Falzetti F,Di Ianni M

    更新日期：2013-08-01 00:00:00

  • Anti-tissue factor pathway inhibitor (TFPI) therapy: a novel approach to the treatment of haemophilia.

    abstract：:Novel approaches to the treatment of haemophilia are needed due to the limitations of the current standard of care, factor replacement therapy. Aspirations include lessening the treatment burden and effectively preventing joint damage. Treating haemophilia by restoring thrombin generation may be an effective approach....

    journal_title：International journal of hematology

    pub_type： 杂志文章,评审

    doi：10.1007/s12185-018-2548-6

    authors： Chowdary P

    更新日期：2020-01-01 00:00:00

  • A 13-24 C-terminal peptide related to PF4 accelerates hematopoietic recovery of progenitor cells in vivo in mice treated with 5-fluorouracil.

    abstract：:We have recently reported that platelet factor 4 (PF4), a megakaryocyte-platelet protein, is a potent inhibitor of human and murine megakaryocytopoiesis. In addition, PF4 accelerated the recovery of the marrow precursor cells in 5-fluorouracil (5-FU) treated mice. We show in this study that a slight modification of th...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1016/s0925-5710(97)00065-0

    authors： Aïdoudi S,Lebeurier I,Amiral J,Quentin G,Caen JP,Han ZC

    更新日期：1997-12-01 00:00:00

  • Evaluation of HNA-expressing cell line-based antigen capture systems and a solid-phase system for detecting HNA-1a antibodies.

    abstract：:Granulocyte immunofluorescence and granulocyte agglutination tests are standard methods for detecting human neutrophil antigen (HNA) antibodies (Abs); however, these require a typed panel of neutrophils, which can be time-consuming to develop, and it remains difficult to determine antibody specificity in some cases. W...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/s12185-015-1751-y

    authors： Amakishi E,Irie Y,Nishizawa K,Kamada H,Nakajima F,Matsuyama N,Ishii H,Matsukura H,Yasui K,Hirayama F

    更新日期：2015-04-01 00:00:00

  • Constitutively activated Rho guanosine triphosphatases regulate the growth and morphology of hairy cell leukemia cells.

    abstract：:Hairy cell leukemia (HCL) is a rare type of chronic B-cell leukemia characterized by the hairy morphology of the leukemia cells. All of 5 HCL samples and an HCL-derived cell line, BNBH-I, showed serrated edges and hairlike projections in May-Grünwald Giemsa stain and protruding actin spikes and lamellipodia in phalloi...

    journal_title：International journal of hematology

    pub_type： 杂志文章

    doi：10.1007/BF02983784

    authors： Zhang X,Machii T,Matsumura I,Ezoe S,Kawasaki A,Tanaka H,Ueda S,Sugahara H,Shibayama H,Mizuki M,Kanakura Y

    更新日期：2003-04-01 00:00:00