The enantioselective participation of (S)- and (R)-diaminovaleric acids in the formation of delta-aminolevulinic acid in cyanobacteria.

abstract：:The Mr approximately equal to 90,000 heat shock protein, hsp90, readily interacts with the glucocorticoid receptor to form the 9 S, non-DNA-binding receptor complex. This receptor is stabilized in cytosolic preparations by sodium molybdate. In analogy, sodium molybdate stabilizes a 9 S form of the dioxin receptor. Pol...

journal_title：Biochemical and biophysical research communications

authors： Denis M,Cuthill S,Wikström AC,Poellinger L,Gustafsson JA

更新日期：1988-09-15 00:00:00

abstract：:A major problem in the treatment of type 1 diabetes mellitus is the limited availability of alternative sources of insulin-producing cells for islet transplantation. In this study, we investigated the effect of bone morphogenetic protein 4 (BMP-4) treatments of gnotobiotic porcine skin-derived stem cells (gSDSCs) on t...

journal_title：Biochemical and biophysical research communications

authors： Yang JH,Lee SH,Heo YT,Uhm SJ,Lee HT

更新日期：2010-07-09 00:00:00

abstract：:The (45)Ca(2+) influx into right-side-out resealed ghosts (RG) prepared from human red blood cells (RBC) was measured. The (45)Ca(2+) equilibration occurred with t(1/2)=2.5 min and the steady-state was reached after 17 min with the level of 22+/-2 micromol/L(packed cells) at 37 degrees C. The rate of the influx was 97...

journal_title：Biochemical and biophysical research communications

authors： Hudec R,Lakatos B,Orlický J,Varecka L

更新日期：2004-12-24 00:00:00

abstract：:Rapidly activating Kv4 voltage-gated ion channels are found in heart, brain, and diverse other tissues including colon and uterus. Kv4.3 can co-assemble with KChIP ancillary subunits, which modify kinetic behavior. We examined the affinity and use dependence of nifedipine block on Kv4.3 and its modulation by KChIP2b. ...

journal_title：Biochemical and biophysical research communications

authors： Bett GC,Morales MJ,Strauss HC,Rasmusson RL

更新日期：2006-02-24 00:00:00

abstract：:A 13 kb rat Cu/ZnSOD genomic clone has been purified from a rat liver genomic library and completely characterized by restriction mapping, detailed sequencing and Southern blot analysis. This gene spans approximately 6 kb and contains five exons and four introns. Comparison of rat, mouse, and human Cu/ZnSOD genes reve...

journal_title：Biochemical and biophysical research communications

authors： Hsu JL,Visner GA,Burr IA,Nick HS

更新日期：1992-07-31 00:00:00

abstract：:The ability of tissue plasminogen activator (tPA) to induce human umbilical vein endothelial (HUVE) cell migration was studied using an in vitro, serum-free wound assay system. At pharmacological doses, tPA stimulated HUVE cell migration dose-dependently. Treatment of cells with epsilon amino caproic acid (EACA) to de...

journal_title：Biochemical and biophysical research communications

authors： Inyang AL,Tobelem G

更新日期：1990-09-28 00:00:00

abstract：:Phosphorylation influences DNA binding and transactivator capabilities of multiple transcription factors. In this study, we demonstrate that the POU-domain transcription factor, Oct-3, can be phosphorylated in vivo. In addition, we show that in COS-1 cells Oct-3 is phosphorylated exclusively on serine residues. Lastly...

journal_title：Biochemical and biophysical research communications

authors： Rosfjord E,Scholtz B,Lewis R,Rizzino A

更新日期：1995-07-26 00:00:00

abstract：:The carcinogenic function of arachidonate lipoxygenase12 (Alox12) has been reported in various cancers. However, little is known on the role of Alox12 in lung cancer. Here, we demonstrate that Alox12 is upregulated and contributes to biological activities of lung cancer through multiple mechanisms. We found that Alox1...

journal_title：Biochemical and biophysical research communications

authors： Chen J,Tong W,Liao M,Chen D

更新日期：2020-04-16 00:00:00

abstract：:We initiated the present work as part of an effort to identify and characterize genes from the EST2-HMG14 region from human chromosome 21 potentially responsible for some of the Down syndrome (DS) features. Genomic sample sequencing with cosmid clone A1047 located in the ETS2-HMG14 region of chromosome 21 has led to t...

journal_title：Biochemical and biophysical research communications

authors： Vidal-Taboada JM,Sanz S,Egeo A,Scartezzini P,Oliva R

更新日期：1998-09-29 00:00:00

abstract：:A procedure is described for preparation of homogeneous inositol monophosphate phosphatase (EC 3.1.3.25) from beef brain in less than 2 days with an overall recovery of 15-25%. This enzyme, an essential part of the inositol phospholipid cycle in brain, is a proposed site of action of lithium ions in manic-depressive d...

journal_title：Biochemical and biophysical research communications

authors： Meek JL,Rice TJ,Anton E

更新日期：1988-10-14 00:00:00

abstract：:The tenascin-R (TN-R) gene encodes a multidomain extracellular matrix glycoprotein belonging to the tenascin family. It is detectable mainly in oligodendrocytes and neuronal subpopulations of the central nervous system. In this report, we describe the structure of the 5'-region of the mouse TN-R gene and characterise ...

journal_title：Biochemical and biophysical research communications

authors： Putthoff P,Akyüz N,Kutsche M,Zardi L,Borgmeyer U,Schachner M

更新日期：2003-09-05 00:00:00

abstract：:Alanine racemase (Alr) is a pyridoxal-5'-phosphate-dependent (PLP) enzyme that catalyzes a reversible racemization between the enantiomers of alanine. d-Alanine is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan, and its inhibition is lethal to prokaryotes, which makes it an attra...

journal_title：Biochemical and biophysical research communications

authors： Dong H,Hu T,He G,Lu D,Qi J,Dou Y,Long W,He X,Ju J,Su D

更新日期：2018-02-26 00:00:00

abstract：:Activation of the epidermal growth factor receptor (EGF-R) tyrosine kinase was investigated in membrane preparations as well as intact A431 cells, using anti-EGF-R antibodies directed against extra- and intracellular receptor domains. In vitro assay conditions were mimicked on whole cells by a mild detergent treatment...

journal_title：Biochemical and biophysical research communications

authors： Spaargaren M,Defize LH,de Laat SW,Boonstra J

更新日期：1990-09-14 00:00:00

abstract：:We investigated the contributions of dietary fat and dietary carbohydrate to the development of fatty liver induced by western diet (WD). Compared with WD-fed wild type (WT) mice, livers of WD-fed ChREBP(-/-) mice showed lipid droplets of varying sizes around the hepatic lobules, while hepatic triglyceride and cholest...

journal_title：Biochemical and biophysical research communications

authors： Wu W,Tsuchida H,Kato T,Niwa H,Horikawa Y,Takeda J,Iizuka K

更新日期：2015-06-12 00:00:00

abstract：:A type II DNA topoisomerase has been partially purified from calf thymus mitochondria by a combination of differential centrifugation and column chromatography. The mitochondrial enzyme was inhibited by amsacrine (m-AMSA) slightly at 0.5 microM, significantly at 5.0 microM, and completely at 50 microM. A similar profi...

journal_title：Biochemical and biophysical research communications

authors： Lin JH,Castora FJ

更新日期：1991-04-30 00:00:00

abstract：:RNF8 is a nuclear protein having an N-terminal forkhead-associated (FHA) domain and a C-terminal RING-finger (RF) domain. Depletion of RNF8 caused cell growth inhibition and cell cycle arrest at not only S but also G2/M phases. In addition, cell death was frequently observed in RNF8-depleted cells. Analyses of time-la...

journal_title：Biochemical and biophysical research communications

authors： Yoshioka T,Kimura M,Saio M,Era S,Okano Y

更新日期：2011-06-24 00:00:00

abstract：:During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylger...

journal_title：Biochemical and biophysical research communications

authors： Bruscalupi G,Castellano F,Sacco S,Trentalance A

更新日期：1994-05-16 00:00:00

abstract：:Subcellular distribution of a novel annexin, annexin XI, was examined in rat tissues. As we have previously reported, annexin XI mainly localizes in nuclei of 3Y1, the rat embryonic fibroblast cell line; however, immunoperoxidase staining was not particularly nuclear in most of the tissues examined in adult rats. Nucl...

journal_title：Biochemical and biophysical research communications

authors： Mamiya N,Iino S,Mizutani A,Kobayashi S,Hidaka H

更新日期：1994-07-15 00:00:00

abstract：:SecB, a molecular chaperone in Escherichia coli, binds a subset of precursor proteins that are exported across the plasma membrane via the Sec pathway. Previous studies showed that SecB bound directly to the mature region rather than to the signal sequence of the precursor protein. To determine the binding pattern of ...

journal_title：Biochemical and biophysical research communications

authors： Tang Y,Pan X,Tai PC,Sui SF

更新日期：2010-03-19 00:00:00

abstract：:Androgen receptor (AR) recognizes and binds to 15-bp palindromic androgen response element (ARE) sequences with high affinity in vitro, which consist of two hexameric half-sites arranged as inverted repeats with a 3-bp spacer. Although a few near-consensus ARE sequences have been actually identified in the transcripti...

journal_title：Biochemical and biophysical research communications

authors： Horie-Inoue K,Bono H,Okazaki Y,Inoue S

更新日期：2004-12-24 00:00:00

abstract：:Hand-foot skin reaction (HFSR) is a common side effect of multiple tyrosine kinase inhibitors (mTKIs). HFSR can necessitate dose reductions or interruption of therapy owing to its negative effect on the quality of life. Therefore, effective use of mTKIs requires measures to prevent HFSR. We evaluated the effect of pro...

journal_title：Biochemical and biophysical research communications

authors： Shichiri H,Yamamoto K,Tokura M,Ishida T,Uda A,Bito T,Nishigori C,Nakagawa T,Hirano T,Yano I,Hirai M

更新日期：2017-04-01 00:00:00

abstract：:Cellular prion protein, PrP(C), is essential for the development of prion diseases where it is considered to be a substrate for the formation of the disease-associated conformer, PrP(Sc). In sheep, PrP(C) is abundant in neuronal tissue and is also found at lower concentrations in a range of non-neuronal tissues, inclu...

journal_title：Biochemical and biophysical research communications

authors： Maddison BC,Whitelam GC,Gough KC

更新日期：2007-02-02 00:00:00

abstract：:A voltage-activated proton current in human cardiac fibroblasts, measured using the whole-cell recording configuration of the patch-clamp technique, is reported. Increasing the pH of the bathing solution shifted the current activation threshold to more negative potentials and increased both the current amplitude and i...

journal_title：Biochemical and biophysical research communications

authors： El Chemaly A,Guinamard R,Demion M,Fares N,Jebara V,Faivre JF,Bois P

更新日期：2006-02-10 00:00:00

abstract：:The EPR spectra of the spin labels attached to loops L11 and L12 of kinesin were resolved into slow (rotational correlation time, tau=10-45 ns) and fast (tau=2 ns) components. The fraction of the slow component increased considerably when kinesin was complexed with a microtubule (MT). On MT binding and in the presence...

journal_title：Biochemical and biophysical research communications

authors： Yamada MD,Maruta S,Yasuda S,Kondo K,Maeda H,Arata T

更新日期：2007-12-21 00:00:00

abstract：:Pancreatic islets of Langerhans were perifused with Krebs-bicarbonate solution containing glucose (5 and 10 mM). The perifusate was spiked with tetradeuterated hepoxilin A3 and was extracted and analysed by gas chromatography-mass spectrometry using NICI detection. Evidence is presented showing the presence of hepoxil...

journal_title：Biochemical and biophysical research communications

authors： Pace-Asciak CR,Martin JM,Corey EJ,Su WG

更新日期：1985-04-30 00:00:00

abstract：:Despite the fact that the phosphorylation-mediated regulation of L-type Ca channels is viewed as a model of ion channel regulation, much remains to be learned about the protein phosphorylation and dephosphorylation reactions that underlie the regulation of the channels. The channel isoform most well studied biochemica...

journal_title：Biochemical and biophysical research communications

authors： Zhao XL,Gutierrez LM,Chang CF,Hosey MM

更新日期：1994-01-14 00:00:00

abstract：:The human amyloid beta protein is a major component of brain amyloid found in patients with Alzheimer's disease. As an initial step to understand the biological function of its precursor protein, we have isolated cDNA for the mouse homolog of the human beta protein precursor. Comparison of the predicted amino acid seq...

journal_title：Biochemical and biophysical research communications

authors： Yamada T,Sasaki H,Furuya H,Miyata T,Goto I,Sakaki Y

更新日期：1987-12-16 00:00:00

abstract：:How rod-shaped bacteria form and maintain their shape is an important question in bacterial cell biology. Results from fluorescent light microscopy have led many to believe that the actin homolog MreB and a number of other proteins form long helical filaments along the inner membrane of the cell. Here we show using el...

journal_title：Biochemical and biophysical research communications

authors： Swulius MT,Chen S,Jane Ding H,Li Z,Briegel A,Pilhofer M,Tocheva EI,Lybarger SR,Johnson TL,Sandkvist M,Jensen GJ

更新日期：2011-04-22 00:00:00

abstract：:Binding of phorbol-12,13-dibutyrate (PDBu), a tumor promoter, to quiescent Swiss 3T3 cells increased the number of hexose carriers, resulting in stimulation of membrane transport of 3-O-methylglucose (3MeGlu) in a Ca2+-dependent fashion. Extracellular Ca2+ was necessary to initiate the binding of PDBu to its receptor,...

journal_title：Biochemical and biophysical research communications

authors： Kitagawa K,Nishino H,Iwashima A

更新日期：1985-04-16 00:00:00

abstract：:Neuropathic pain is triggered by damage to or as a result of the dysfunction of the somatosensory nervous system. Gene expression profiling using DNA microarray and real-time PCR have emerged as powerful tools for the elucidation of pain-specific pathways and identification of candidate biomarkers and therapeutic targ...

journal_title：Biochemical and biophysical research communications

authors： Wan G,Yang K,Lim Q',Zhou L,He BP,Wong HK,Too HP

更新日期：2010-10-01 00:00:00