Metalloproteinase expression by control and telomerase immortalized human endometrial endothelial cells.

abstract：AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...

journal_title：Histology and histopathology

authors： Kim SH,Lee SH,Choi YL,Wang LH,Park CK,Shin YK

更新日期：2008-12-01 00:00:00

abstract：:Cerebral cavernous malformations (CCMs) are described as vascular lesions consisting of endothelial-lined dilated vessels embedded in a connective tissue sheath without intervening parenchyma between them. Their anatomical connections with the normal blood vessels are still enigmatic and the fine three-dimensional (3-...

journal_title：Histology and histopathology

authors： Toralba S,Landemore G,Coquemont M,Plancoulaine B,Chapon F

更新日期：2014-08-01 00:00:00

abstract：:To understand the role of microtubules and microfilaments in regulating endothelial monolayer integrity and repair, and since microtubules and microfilaments show some co-alignment in endothelial cells, we tested the hypothesis that microtubules organize microfilament distribution. Disruption of microtubules with colc...

journal_title：Histology and histopathology

authors： Lee JS,Gotlieb AI

更新日期：2005-04-01 00:00:00

abstract：:Various microscopic methods have been used to analyze the morphology and molecular distribution of cells and tissues. Using conventional procedures, however, ischemic or anoxic artifacts are inevitably caused by tissue-resection or perfusion-fixation. The in vivo cryotechnique (IVCT) was developed to overcome these pr...

journal_title：Histology and histopathology

authors： Ohno N,Terada N,Saitoh S,Zhou H,Fujii Y,Ohno S

更新日期：2007-11-01 00:00:00

abstract：:We report a case of subcutaneous fat necrosis of a newborn child which appeared 9 days after birth and was cured without any complications. We propose the reclassification of the etiological factors accompanying this lesion by classifying them in a plurietiological syndrome with some basic or essential factors and oth...

journal_title：Histology and histopathology

authors： Salas Valién JS,Ribas Ariño MT,Egido Romo M,Palau Benavides MT

更新日期：1990-01-01 00:00:00

abstract：:Aurora A and Aurora B are serine-threonine kinase proteins which have both been implicated in human carcinogenesis through development of aneuploidy and chromosomal instability. The aim of the study is to assess the correlation of both markers with clinical and pathological parameters in patients with bladder cancer o...

journal_title：Histology and histopathology

authors： Bufo P,Sanguedolce F,Tortorella S,Cormio L,Carrieri G,Pannone G

更新日期：2010-11-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:GLI-similar (Glis) 1-3 proteins constitute a subfamily of the Krüppel-like zinc finger transcription factors that are closely related to the Gli family. Glis1-3 play critical roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Mutations in GLIS2 have been lin...

journal_title：Histology and histopathology

authors： Kang HS,ZeRuth G,Lichti-Kaiser K,Vasanth S,Yin Z,Kim YS,Jetten AM

更新日期：2010-11-01 00:00:00

abstract：:The terms construct or tissue equivalent refer to neotissue produced by tissue engineering techniques. The elements forming the construct are scaffolds on which cells are "recreated" to form an engineered-tissue sensitive to certain cell signals. The ability of the cells to expand and differentiate on the scaffold is ...

journal_title：Histology and histopathology

authors： Buján J,Pascual G,Corrales C,Gómez-Gil V,Rodríguez M,Bellón JM

更新日期：2005-07-01 00:00:00

abstract：:Dysadherin, a cancer associated cell membrane glycoprotein, has been reported to downregulate E-cadherin. Aberrant expression of E-cadherin has been associated with the development of metastases in patients with cancer. Even though the expression of dysadherin and E-cadherin has been studied in primary non-small cell ...

journal_title：Histology and histopathology

authors： Mitselou A,Batistatou A,Nakanishi Y,Hirohashi S,Vougiouklakis T,Charalabopoulos K

更新日期：2010-10-01 00:00:00

abstract：:Beta-catenin expression in small cell lung carcinomas (SCLC) was investigated by immunohistochemical method using antibodies against beta-catenin. 50 pre-treatment biopsies were examined and the relationship between beta-catenin expression and the patients' relevant clinical characteristics, response to chemotherapy, ...

journal_title：Histology and histopathology

authors： Rodríguez-Salas N,Palacios J,de Castro J,Moreno G,González-Barón M,Gamallo C

更新日期：2001-04-01 00:00:00

abstract：:A novel family of evolutionally conserved neuronal guidance cues, including ligands (i.e., Slit, netrin, epherin, and semaphorin) and their corresponding receptors (i.e., Robo, DCC/Unc5, Eph and plexin/ neuropilin), has been identified to play a crucial role in axon pathfinding and branching as well as neuronal cell m...

journal_title：Histology and histopathology

authors： Liao WX,Wing DA,Geng JG,Chen DB

更新日期：2010-09-01 00:00:00

abstract：:Although traditionally little attention has been paid to the interplay between neurotrophins and the cell cycle, a number of recent findings suggest an important role for these growth factors in the regulation of this aspect of the cellular physiology. In this article, we review the evidence from a number of studies t...

journal_title：Histology and histopathology

authors： López-Sánchez N,Frade JM

更新日期：2002-10-01 00:00:00

abstract：:Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. In addition, spectrins have been implicated in TGF-beta signaling. The aim of the present study was to analyze the expression and localization of beta...

journal_title：Histology and histopathology

authors： Jiang X,Gillen S,Esposito I,Giese NA,Michalski CW,Friess H,Kleeff J

更新日期：2010-12-01 00:00:00

abstract：:Anthracyclines are one of the most effective anticancer drugs ever developed, but their clinical use has been hampered by the risk of severe cardiotoxicity. In this study, we investigated whether rabbits exposed to a different cumulative dose of anthracycline suffer from immunohistochemically detectable vascular toxic...

journal_title：Histology and histopathology

authors： Nachtigal P,Sterba M,Popelová O,Večeřová L,Kudláčková Z,Jirkovský E,Geršl V

更新日期：2011-05-01 00:00:00

abstract：:The presence of synaptophysin, a presynaptic Ca2+ binding glycoprotein, has been analyzed in the cochlear nucleus complex of the adult cat using an antisynaptophysin monoclonal antibody. Synaptophysin immunoreactivity was differently distributed between regions of cochlear nuclei. Terminal boutons contacting directly ...

journal_title：Histology and histopathology

authors： Gil-Loyzaga P,Bartolomé MV,Ibáñez A

更新日期：1998-04-01 00:00:00

abstract：:The view of how astrocytes, a type of glial cells, contribute to the functioning of the central nervous system (CNS) has changed greatly in the last decade. Although glial cells outnumber neurons in the mammalian brain, it was considered for over a century that they played a subservient role to neurons. This view chan...

journal_title：Histology and histopathology

authors： Potokar M,Stenovec M,Kreft M,Gabrijel M,Zorec R

更新日期：2011-02-01 00:00:00

abstract：:In the cutaneous nerves, unmyelinated nerve fibers outnumber the myelinated ones but are scarcely analyzed, especially at autopsy. This indifference toward the pathology of unmyelinated nerve fibers may be due to the necessity of electron microscopic analyses and, more importantly, the obscurity of pathological altera...

journal_title：Histology and histopathology

authors： Kanda T

更新日期：2000-01-01 00:00:00

abstract：:A rat IgG2a monoclonal antibody against a stage-specific fetal glycoprotein with a molecular mass of 68 kDa (FGP68) was produced and applied to paraffin sections. This monoclonal antibody was used to compare the expression of FGP68 with that of both alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in 75 hepa...

journal_title：Histology and histopathology

authors： Kato M,Shinozawa T,Kato S,Terada T

更新日期：2004-07-01 00:00:00

abstract：:CD24 is known to be an important diagnostic and prognostic marker of several major cancers affecting females. We aimed to determine CD24 expression in normal, hyperplastic, and carcinomatous endometrium and its correlation with estrogen and progesterone receptor expression. A total of 271 cases including 62 normal/atr...

journal_title：Histology and histopathology

authors： Kim KH,Choi JS,Kim JM,Choi YL,Shin YK,Lee HC,Seong IO,Kim BK,Chae SW,Kim SH

更新日期：2009-03-01 00:00:00

abstract：:Autophagy and apoptosis are two important molecular mechanisms that maintain cellular homeostasis under stress conditions. Autophagy represents an intracellular mechanism responsible for turnover of organelles and long-lived proteins through a lysosome-dependent degradation pathway. Cell death signals or sustained str...

journal_title：Histology and histopathology

authors： Oral O,Akkoc Y,Bayraktar O,Gozuacik D

更新日期：2016-05-01 00:00:00

abstract：:Circadian and seasonal variations were observed in the karyometric index of pinealocytes in the cortical and medullary regions of the distal pineal body. The study involved 70 Wistar rats over a 24-hour interval (0:6, 10:00, 14:00, 18:00, 22:00, 02:00, 06:00 h) during two natural photoluminous periods, i.e. late summe...

journal_title：Histology and histopathology

authors： Cimas García C,Martínez Soriano F,Ruiz Torner A

更新日期：1992-10-01 00:00:00

abstract：:The mandible has a mixed embryological origin, and its growth is associated with the secondary cartilage of the condyle process (CP). In this area, growth depends on an array of intrinsic and extrinsic factors that influence protein metabolism. In the present study, we used an adolescent rat model to evaluate the grow...

journal_title：Histology and histopathology

authors： de Oliveira BC,de Oliveira F,Martini DT,Prisco CR,da Silva Riguetti MM,Liberti EA,de Campos Boldrini S

更新日期：2010-01-01 00:00:00

abstract：:Glomerular alterations of experimental diabetes mellitus are observed in animals submitted to a reduction in renal mass, suggesting that some mechanisms responsible for the progression of renal disease are common. The aim of this study was to investigate the effect of nephrectomy on the renal function and morphology o...

journal_title：Histology and histopathology

authors： Lopes GS,Lemos CC,Mandarim-De-Lacerda CA,Bregman R

更新日期：2004-10-01 00:00:00

abstract：:This study evidences the presence of primordial germ cells, in tissue squash preparations and sections from hematological malignancies. Primordial germ cells were identified by their morphology, the intense PAS, PAS-D reaction and presence of calcium-activated neutral proteinase. Primordial germ cells gave rise to nuc...

journal_title：Histology and histopathology

authors： Logothetou-Rella H

更新日期：1996-10-01 00:00:00

abstract：:There is now evidence that estrogens and androgens are exerting their effects in different tissues throughout the body. In order to determine the sites of action of these steroids, studies have been performed to identify at the cellular level the localization of androgen receptor (AR) and the two estrogen receptor (ER...

journal_title：Histology and histopathology

authors： Pelletier G

更新日期：2000-10-01 00:00:00

abstract：:Mesothelial cells (MC) obtained from the human omentum are a good alternative to the use of endothelial cells (EC) as a covering for vascular prostheses of polytetrafluoroethylene (PTFE), given the antithrombogenic properties and good behavior in vitro of mesothelial cells. We studied the behaviour of mesothelial cell...

journal_title：Histology and histopathology

authors： Buján J,García-Honduvilla N,Hernando A,Bellón JM

更新日期：1995-10-01 00:00:00

abstract：:We describe a new technique, decalcification by perfusion, for the softening of bony tissue. The blood circulatory system was perfused in 16 rats via a cannula through the left heart ventricle with a fixative followed by New Decalc (an acidic demineralizer) for 30-240 minutes. Perfusion decalcification for 120 minutes...

journal_title：Histology and histopathology

authors： Nilsson M,Hellström S,Albiin N

更新日期：1991-07-01 00:00:00

abstract：:Smads are signal transducers for the members of the TGF-beta superfamily. Of these Smads, Smad4 is essential for TGF-beta signaling. The purpose of this study was to elucidate Smad4 expression and localization in 65 gastric adenomas, 49 intestinal-type and 39 diffuse type of gastric adenocarcinomas (including 12 cases...

journal_title：Histology and histopathology

authors： Kim JY,Park DY,Kim GH,Choi KU,Lee CH,Huh GY,Sol MY,Song GA,Jeon TY,Kim DH,Sim MS

更新日期：2005-04-01 00:00:00

abstract：:Cocaine- and amphetamine-regulated transcript peptide (CART) is a neuromediator and/or neuromodulator in nerve structures within the gastrointestinal tract, but knowledge about its distribution, functions and co-localisation with other neuronal factors, especially in humans, is very scarce. During the present investig...

journal_title：Histology and histopathology

authors： Gonkowski S,Kamińska B,Landowski P,Całka J

更新日期：2013-07-01 00:00:00