Effect of cataract surgery with intraocular lens implant on frequency doubling perimetry.

abstract：:Purpose/Aim: The goal of this study is to reveal how age-related changes in phospholipid (PL) composition in the fiber cell plasma membranes of the human eye lens affect the cholesterol (Chol) content at which Chol bilayer domains (CBDs) and Chol crystals start to form.Materials and Methods: Saturation-recovery electr...

journal_title：Current eye research

authors： Mainali L,Pasenkiewicz-Gierula M,Subczynski WK

更新日期：2020-02-01 00:00:00

abstract：:Thrombospondins are a family of large multi-domain glycoproteins described as matricelluar proteins based on their ability to interact with a broad range of receptors, matrix molecules, growth factors or proteases, and to modulate array of cellular functions including intracellular signaling, proliferation and migrati...

journal_title：Current eye research

authors： Masli S,Sheibani N,Cursiefen C,Zieske J

更新日期：2014-08-01 00:00:00

abstract：:Intracellular binding proteins have been identified and isolated from B cells by their ability to bind to the synthetic peptide (1169-1191), the major immunodominant epitope of bovine interphotoreceptor retinoid-binding protein (IRBP) coupled to cyanogen bromide activated Sepharose 4B. After SDS-PAGE, two discrete pro...

journal_title：Current eye research

authors： Rengarajan K,de Smet MD,Chader GJ,Wiggert B

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:To investigate the spectral content of intraocular pressure (IOP) pulse wave by advanced spectral signal processing of continuous IOP readings obtained by dynamic contour tonometry. PATIENTS AND METHODS:A non-interventional case-control study included 20 healthy subjects, 20 previously untreated primary open a...

journal_title：Current eye research

authors： Božić M,Dukić ML,Stojković M

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:Purpose. To develop a rapid and accurate method for the quantification of reduced glutathione (GSH) and oxidized glutathione (GSSG) using micro-quantities of ocular lens. Methods. The epithelium, cortex and nucleus of the lens were separated and also the whole lens was homogenized in 3% metaphosphoric acid. ...

journal_title：Current eye research

authors： Liu S,Ansari NH,Wang C,Wang L,Srivastava SK

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To characterize the effects that mode of sampling and overnight eye closure have on the nature of caseinolytic activity recovered in tear fluid. METHODS:Reflex, open and closed (R, O and C) eye tear fluids were collected by microcapillary tubes or from the inferior formix by Schirmer strip. Microcapillary coll...

journal_title：Current eye research

authors： Sakata M,Sack RA,Sathe S,Holden B,Beaton AR

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:To study early signs of neuronal and glial differentiation in the human embryonic retina. MATERIALS AND METHODS:6.5-to 8-week-old human embryos were obtained from elective abortions. The neuroretinas were kept in culture as full-thickness sheets for 7-42 days. RESULTS:The control retinas consisted of a neurob...

journal_title：Current eye research

authors： Engelsberg K,Ehinger B,Ghosh F

更新日期：2008-02-01 00:00:00

abstract：PURPOSE/AIM OF THE STUDY:The aim of this study is to investigate the effect of pseudoexfoliation (PEX) and PEX-induced dry eye on central corneal thickness (CCT). MATERIALS AND METHODS:This cross-sectional study consists of total 270 eyes of 135 patients (67 females, 68 males) in total. After excluding the PEX (-) 32 ...

journal_title：Current eye research

authors： Akdemir MO,Kirgiz A,Ayar O,Kaldirim H,Mert M,Cabuk KS,Taskapili M

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Acanthamoeba keratitis is a sight-threatening corneal infection. It is known that: (i) more amoebae bind to the surface of injured corneas than to the normal corneal surface and (ii) mannose-containing glycoproteins (GPs) possess binding sites for Acanthamoeba. The present study was undertaken to determine whet...

journal_title：Current eye research

authors： Jaison PL,Cao Z,Panjwani N

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association between corneal temperature on ocular surface and stability of tear film, and define the normal reference range of corneal surface temperature in the population of Pudong New Area, Shanghai, China. METHODS:Temperature of cornea (TOC) and tear film break-up time (BUT) were measu...

journal_title：Current eye research

authors： Yang W,Zhang L

更新日期：2017-05-01 00:00:00

abstract：:Purpose: To investigate to what extent the OSDI can be utilized as a discriminative test for clinical findings. Methods: One thousand and ninety patients with dry eye disease (DED) were consecutively included and examined for osmolarity, tear film break-up time (TFBUT), ocular protection index (OPI), ocular surface st...

journal_title：Current eye research

authors： Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Hua Y,Eidet JR,Stojanovic A,Dartt DA,Utheim TP

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To examine whether transforming growth factor-beta 2 (TGF-beta 2) induces the expression of alpha-smooth muscle actin (SMA), a biochemical marker of myofibroblasts, in cultured bovine retinal pigment epithelial (RPE) cells. METHODS:Bovine RPE cells were cultured in F-12 nutrient mixture supplemented with 5% fe...

journal_title：Current eye research

authors： Kurosaka D,Muraki Y,Inoue M,Katsura H

更新日期：1996-11-01 00:00:00

abstract：:The corneal endothelium is known to contain gap junctions on its lateral borders. Here we show that the endothelial cells of the rabbit cornea are highly dye coupled. Lucifer Yellow CH introduced into a single cell through either an intracellular glass microelectrode or a patch electrode rapidly spreads into its neigh...

journal_title：Current eye research

authors： Rae JL,Lewno AW,Cooper K,Gates P

更新日期：1989-08-01 00:00:00

abstract：:The effects of light damage were studied in four inbred strains of albino rats, Fischer (F344), Lewis (L), Wistar (W), and Buffalo (BUF). Thirty-five-day-old rats (3 from each strain) were kept in cyclic light for two weeks, after which they were exposed to constant fluorescent light (180-190 foot-candles, 490-580 nm)...

journal_title：Current eye research

authors： Borges JM,Edward DP,Tso MO

更新日期：1990-08-01 00:00:00

abstract：PURPOSE:To investigate the multifocal electroretinogram (mfERG) and subjective function in early age-related maculopathy (ARM). METHODS:Seventeen subjects with early ARM with visual acuity (VA) of 6/12 or better and 20 age-matched control subjects were examined. We assessed mfERGs, high and low contrast distance VA, n...

journal_title：Current eye research

authors： Feigl B,Brown B,Lovie-Kitchin J,Swann P

更新日期：2004-10-01 00:00:00

abstract：:Bovine vitreous body and aorta contain extractable leukocyte elastase inhibitors, which were purified by gel filtration and affinity chromatography on agarose-pancreatic elastase. The purified inhibitor preparation from aorta was resolved by polyacrylamide gel electrophoresis into a main band migrating slightly faster...

journal_title：Current eye research

authors： Arsenis C,Kuettner KE,Eisenstein R

更新日期：1988-02-01 00:00:00

abstract：PURPOSE:To study retinal neovascularization (RNV) inhibition by intravitreal injections (IVs) of ranibizumab, sTie2 fusion protein (sTie2-Fc), and a combined therapy in an oxygen-induced retinopathy (OIR) model. MATERIALS AND METHODS:An OIR mouse model was used to simulate RNV in retinopathy of prematurity (ROP); and ...

journal_title：Current eye research

authors： Jiang C,Ruan L,Zhang J,Huang X

更新日期：2018-09-01 00:00:00

abstract：AIM:To test the feasibility of implanting human anterior lens capsules (HALCs) with porcine corneal endothelial cells (pCEC) in vivo in Göttingen minipigs and at the same time test the suitability of Göttingen minipig as model for endothelial keratoplasty. MATERIALS AND METHODS:Cell-carrier constructs of decellularize...

journal_title：Current eye research

authors： Telinius N,Spinozzi D,Rasic D,Dapena I,Baandrup U,Miron A,Oellerich S,Hjortdal J

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To investigate the agreement of angular locations of retinal nerve fiber layer (RNFL) defect margins in glaucomatous eyes by using red-free fundus photographs and Cirrus high-definition optical coherence tomography (OCT) RNFL deviation and thickness maps. METHODS:We examined 380 RNFL defects that showed clear ...

journal_title：Current eye research

authors： Hwang YH,Kim YY,Kim HK,Sohn YH

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Phoria is used in the diagnosis of binocular dysfunctions, such as convergence insufficiency. A common treatment for convergence insufficiency is vision therapy, yet it is controversial whether the phoria changes as a result of rehabilitation. Phoria can vary due to the duration and/or the type of prior visual ...

journal_title：Current eye research

authors： Kim EH,Alvarez TL

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:The mechanism by which prostaglandin(PG)F2 alpha increases uveoscleral outflow and lowers intraocular pressure in primates is not known. In cultured human ciliary muscle cells, PGF2 alpha induces the expression of the protooncogene c-fos which is known to induce the transcription of genes such as matrix metallo...

journal_title：Current eye research

authors： Lindsey JD,Kashiwagi K,Boyle D,Kashiwagi F,Firestein GS,Weinreb RN

更新日期：1996-08-01 00:00:00

abstract：PURPOSE/AIM:To quantitatively analyse the evolution of TUNEL-labeling, after in vivo exposure to UVB. METHODS:Altogether, 16 Sprague Dawley rats were unilaterally exposed in vivo for 15 min to close to threshold dose, 5 kJ/m(2), of ultraviolet radiation in the 300 nm wavelength region. Animals were sacrificed in group...

journal_title：Current eye research

authors： Kronschläger M,Yu Z,Talebizadeh N,Meyer LM,Hallböök F,Söderberg PG

更新日期：2013-08-01 00:00:00

abstract：:Macrophages are invariably present in the intraocular membranes of patients with traumatic proliferative vitreoretinopathy (PVR). There are two sources from which these macrophages could be recruited: adjacent tissues and the systemic circulation. In the study described herein, the role of circulating white blood cell...

journal_title：Current eye research

authors： Gabrielian K,Wang HM,Lee M,Ogden TE,Ryan SJ

更新日期：1994-01-01 00:00:00

abstract：:The effect of monensin on the cytotoxic effect of antitransferrin receptor immunotoxin (IT) was determined on cultured, human retinal pigment epithelial (hRPE) cells. Human RPE cells were treated with 0.1-10,000 ng/ml IT with and without 0.01-0.1 microM monensin, a lysosomotropic reagent that can influence IT activity...

journal_title：Current eye research

authors： Handa JT,Houston LL,Jaffe GJ

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Klotho genes are expressed in limited tissues and have been found to be a pathogenic factor of age-related diseases in mammals, but their expressions and functions in human eyes are yet to be defined. This study was performed to investigate the expression of Klotho family genes in human ocular tissues and anter...

journal_title：Current eye research

authors： Zhang Y,Wang L,Wu Z,Yu X,Du X,Li X

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Taurolidine is a broad-spectrum, non antibiotic antimicrobial agent, not previously tested against the common causes of bacterial keratitis. This study, employing an experimental rabbit model of Staphylococcus aureus keratitis, investigated the effectiveness of topical taurolidine in reducing the number of bact...

journal_title：Current eye research

authors： Oguz H,Ozbilge H,Oguz E,Gurkan T

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To investigate the effect of shaking on corneal endothelial preservation. METHODS:Thirty-six dog corneal buttons were obtained under standard eye bank procedure, after the animals had been sacrificed for cardiovascular experiments in the surgical department. They were equally divided into two groups. In Group ...

journal_title：Current eye research

authors： Wang IJ,Hu FR

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:Post-surgical macular edema is an important clinical problem resulting from breakdown of the blood-retinal barrier (BRB) after surgery. This study was designed to develop a mouse model of post-surgical BRB breakdown. METHODS:Two 25-gauge needles, one for infusion and one for aspiration, were inserted through t...

journal_title：Current eye research

authors： Liu H,Demetriades AM,Xiao WH,Campochiaro PA,Vinores SA

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To examine the efficacy of oral doxycycline treatment (as compared to oral and topical dexamethasone) for inhibiting corneal neovascularization (CNV). METHODS:Following corneal alkali burn, rats were treated daily with oral doxycycline, oral dexamethasone, or topical dexamethasone for 14 days. Control rats wer...

journal_title：Current eye research

authors： Dan L,Shi-long Y,Miao-li L,Yong-ping L,Hong-jie M,Ying Z,Xiang-gui W

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To explore the roles of interleukin (IL)-17A in alkali-induced corneal neovascularization (CRNV). METHODS:Induction of CRNV by alkali injury was performed and compared in recombinant mouse IL-17A protein or anti-mouse IL-17A neutralizing antibody (Ab)-treated mice. The expression of IL-17A, IL-17A receptor (IL...

journal_title：Current eye research

authors： Liu G,Wu H,Lu P,Zhang X

更新日期：2017-03-01 00:00:00