Dye and electrical coupling between cells of the rabbit corneal endothelium.

abstract：PURPOSE:To characterize the pupil light reflex (PLR), electroretinographic (ERG) and tonometric parameters in healthy rat eyes. METHODS:Brown Norway rats were used for experiments. The PLR was evaluated with a computerized pupillometer (n = 27), ERGs were recorded simultaneously from both eyes (n = 27) and IOP was mea...

journal_title：Current eye research

authors： Grozdanic S,Sakaguchi DS,Kwon YH,Kardon RH,Sonea IM

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to report on the evaluation of corneal nerve fiber density and corneal sensation after accelerated corneal collagen cross-linking on keratoconus patients. METHODS:The study was performed on 30 keratoconus eyes (30 participants: 16 M, 14 F; 17-32 years old) treated with accelerated col...

journal_title：Current eye research

authors： Ozgurhan EB,Celik U,Bozkurt E,Demirok A

更新日期：2015-05-01 00:00:00

abstract：:Purpose/Aim: Corneal abrasions and nonhealing corneal epithelial defects are common conditions that cause pain and sometimes are slow to heal. Histatins, a family of histidine-rich peptides, have been implicated in oral and skin epithelial wound healing, and have been shown to be effective in vitro in human corneal ep...

journal_title：Current eye research

authors： Oydanich M,Epstein SP,Gadaria-Rathod N,Guers JJ,Fernandez KB,Asbell PA

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:Pseudoexfoliation (PXF) is a microfibrillopathy involving disordered elastogenesis. Abnormal extracellular matrix (ECM) production underlies the pathophysiology of PXF. The enzyme Lysyl oxidase (LOX) and its isoforms are known to cross-link the elastin and collagen. Though the etiopathogensis of PXF is not well...

journal_title：Current eye research

authors： Gayathri R,Coral K,Sharmila F,Sripriya S,Sripriya K,Manish P,Shantha B,Ronnie G,Vijaya L,Narayanasamy A

更新日期：2016-10-01 00:00:00

abstract：:Four days after corneal inoculation of mice with herpes simplex (type 1) virus (HSV), infected trigeminal ganglion cells with and without calcitonin gene-related peptide (CGRP) antigenicity were examined by electron microscopy in sections treated with colloidal gold labeled antibodies. Cells that contain CGRP were ide...

journal_title：Current eye research

authors： LaVail JH,Meade LB,Dawson CR

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, ...

journal_title：Current eye research

authors： Shi L,Stachon T,Seitz B,Wagenpfeil S,Langenbucher A,Szentmáry N

更新日期：2018-06-01 00:00:00

abstract：:The compound 2-mercaptoacetyl-L-phenylalanyl-L-leucine (HS-Ac-Phe-Leu) is a potent and specific inhibitor of Pseudomonas aeruginosa elastase, effectively inhibiting the elastase activity both, in vitro and within the rabbit cornea. This inhibitor was therefore evaluated as an adjunct to antibiotics (gentamicin) treatm...

journal_title：Current eye research

authors： Spierer A,Kessler E

更新日期：1984-04-01 00:00:00

abstract：:Serum zinc and copper levels were analyzed in 26 retinitis pigmentosa patients and compared with serum zinc levels of a control group. Serum zinc levels were documented to be decreased with a mean concentration of 0.735 +/- 0.167 micrograms/ml (p less than 0.001). Serum copper levels, on the other hand, were found to ...

journal_title：Current eye research

authors： Karcioglu ZA,Stout R,Hahn HJ

更新日期：1984-08-01 00:00:00

abstract：:Posterior vitreous detachment (PVD) and epiretinal membranes occur in a number of vitreoretinal diseases. We have developed an experimental model in which we can provide the morphologic correlation of these dynamic processes. The method provides the opportunity to study epiretinal membrane formation with the scanning ...

journal_title：Current eye research

authors： Matsumoto B,Hsu HT,Blanks JC,Ryan SJ

更新日期：1986-04-01 00:00:00

abstract：PURPOSE:Transforming growth factor -beta2 (TGF-beta2) is a predominant isoform of TGF-betas in the eye and plasmin is a peptidase with many functions. To better understand the pathogenesis of retinal microcirculation disorders, the effects of TGF-beta2 and plasmin on cultured bovine retinal pericytes were investigated....

journal_title：Current eye research

authors： Katsura MK,Mishima HK,Minamoto A,Ishibashi F,Yamashita H

更新日期：2000-03-01 00:00:00

abstract：:The management of opportunistic infections is a significant problem in acquired immunodeficiency syndrome (AIDS) and the development of more effective chemotherapeutic agents is needed. We present the ocular manifestations of an AIDS-like disease in rhesus monkeys experimentally infected with simian immunodeficiency v...

journal_title：Current eye research

authors： Conway MD,Didier P,Fairburn B,Soike KF,Martin L,Murphey-Corb M,Meiners N,Insler MS

更新日期：1990-08-01 00:00:00

abstract：:Perturbations in capillary endothelial cell function are early events in the pathogenesis of diabetic retinopathy. We used tritiated thymidine autoradiography to study the turn-over rate of retinal capillary endothelial cells in retinovascular preparations from normal, untreated diabetic and diabetic mice treated with...

journal_title：Current eye research

authors： Cuthbertson RA,Mandel TE

更新日期：1989-07-01 00:00:00

abstract：:The effects of light damage were studied in four inbred strains of albino rats, Fischer (F344), Lewis (L), Wistar (W), and Buffalo (BUF). Thirty-five-day-old rats (3 from each strain) were kept in cyclic light for two weeks, after which they were exposed to constant fluorescent light (180-190 foot-candles, 490-580 nm)...

journal_title：Current eye research

authors： Borges JM,Edward DP,Tso MO

更新日期：1990-08-01 00:00:00

abstract：:The ocular penetration pathways of three alpha 2-adrenergic agents (p-aminoclonidine, AGN 190342, and clonidine) were investigated in rabbits both in vitro and in vivo. The corneal permeabilities of the compounds correlated positively with their octanol/water distribution coefficients. The ocular drug absorption via c...

journal_title：Current eye research

authors： Chien DS,Homsy JJ,Gluchowski C,Tang-Liu DD

更新日期：1990-11-01 00:00:00

abstract：:Goggles that degrade the retinal image produce axial enlargement of the ocular globe and large myopic refractive errors. Many authors have assumed that visual image degradation itself leads to myopia. Hodos and co-authors have shown, however, that goggled eyes in chicks are considerably warmer than normal. Such temper...

journal_title：Current eye research

authors： Shih YF,Fitzgerald ME,Norton TT,Gamlin PD,Hodos W,Reiner A

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:To explore the roles of interleukin (IL)-17A in alkali-induced corneal neovascularization (CRNV). METHODS:Induction of CRNV by alkali injury was performed and compared in recombinant mouse IL-17A protein or anti-mouse IL-17A neutralizing antibody (Ab)-treated mice. The expression of IL-17A, IL-17A receptor (IL...

journal_title：Current eye research

authors： Liu G,Wu H,Lu P,Zhang X

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:To investigate the tissue blood flow in the neuroretinal rim of the optic disk and macula after rhegmatogenous retinal detachment (RRD) surgery. METHODS:Tissue blood flow in the neuroretinal rim of the optic disk and macula was measured with the Heidelberg retina flowmeter in 53 eyes of 53 patients who had und...

journal_title：Current eye research

authors： Sato EA,Shinoda K,Kimura I,Ohtake Y,Inoue M

更新日期：2007-09-01 00:00:00

abstract：:Thyroxine-treated human lens epithelial cells, HLE B-3, were grown in either a normoxic or hyperoxic atmosphere as a first step in identifying factors related to their increased viability. Reactive oxygen species, ROS, and the apparent mitochondrial membrane potential, Delta Psi(m), were measured using fluorescent pro...

journal_title：Current eye research

authors： Huang L,Yappert MC,Jumblatt MM,Borchman D

更新日期：2008-07-01 00:00:00

abstract：:Previous attempts to prepare monoclonal antibodies (MAbs) against S-antigen, a photoreceptor cell protein involved in the visual process and a potent autoantigen for the induction of experimental autoimmune uveitis (EAU), have yielded MAbs which define only carboxyl terminal epitopes. In this study we devised alternat...

journal_title：Current eye research

authors： Donoso LA,Gregerson DS,Smith L,Robertson S,Knospe V,Vrabec T,Kalsow CM

更新日期：1990-04-01 00:00:00

abstract：PURPOSE:Endothelial cells of different vascular systems may express site-specific adhesion molecules to attract leukocyte subsets. This study describes a method to visualize and compare leukocyte-endothelial interactions in three vascular beds within the same eye in mice. METHODS:Digital in vivo fluorescence microscop...

journal_title：Current eye research

authors： Rosenbaum JT,Brischetto M,Crespo S,Bierwirth M,Oveson K,Planck SR,Becker MD

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Spectral domain optical coherence tomography (SD-OCT) in patients can deliver retinal cross-sectional images with high resolution. This may allow the evaluation of the extent of damage to the retinal pigment epithelium (RPE) and the neurosensory retina after laser treatment. This article aims to investigate ...

journal_title：Current eye research

authors： Framme C,Walter A,Prahs P,Regler R,Theisen-Kunde D,Alt C,Brinkmann R

更新日期：2009-07-01 00:00:00

abstract：:An experimental model of optic nerve ischemia was designed in the rabbit to determine early biochemical alterations, i.e.--changes of high energy phosphate metabolites (ATP and phosphocreatine)--in occlusive and peri-occlusive areas. Vascular occlusion provoked a rapid fall of ATP and phosphocreatine in the optic nerv...

journal_title：Current eye research

authors： Vériac S,Tissié G,Bonne C

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:Recent advances in technology now provide tools capable of tracking genome-wide expression changes occurring in progressive pathological processes. The present experiments were carried out to determine if acetylcholine receptor α 6 subunit (Chrna6) is a reliable retinal ganglion cell (RGC) marker in adult mouse...

journal_title：Current eye research

authors： Munguba GC,Geisert EE,Williams RW,Tapia ML,Lam DK,Bhattacharya SK,Lee RK

更新日期：2013-01-01 00:00:00

abstract：:In these experiments we characterize rabbit and bovine corneal endothelia cell cultured on microporous membrane filters (0.6cm2). Cell cultured bovine or rabbit corneal endothelial cells (subcultures 1-3) were seeded onto Millicell-HA filter inserts. Electrical resistance measured across the cultured monolayers increa...

journal_title：Current eye research

authors： Geroski DH,Hadley A

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Phagocytosis of rod outer segments (ROS) is an important function of retinal pigment epithelial (RPE) cells. Since the details of the process are not fully known, we studied effects of cytokines produced by RPE and photoreceptor cells on phagocytosis of ROS by rat RPE cells. METHODS:RPE cells were isolated and...

journal_title：Current eye research

authors： Hayashi A,Nakae K,Naka H,Ohji M,Tano Y

更新日期：1996-05-01 00:00:00

abstract：PURPOSE:To compare objective optical quality, ocular scattering and aberrations of eyes implanted with an aspheric monofocal intraocular lens (IOL) or an aspheric apodized diffractive multifocal IOL three months after surgery. METHODS:Prospective consecutive nonrandomized comparative cohort study. A total of 80 eyes f...

journal_title：Current eye research

authors： Liao X,Lin J,Tian J,Wen B,Tan Q,Lan C

更新日期：2018-06-01 00:00:00

abstract：:A model for endothelial transport is updated to include recent evidence. We discuss electrolyte movements based on a Na+-K+ ATPase, a Na+-H+ exchanger, a Na+-HCO3 coupler, a Cl- -HCO-3 exchanger, a K+-Cl-coupler, and K+ and anion channels. We discuss near-isotonic transport of fluid on the basis of recent findings of ...

journal_title：Current eye research

authors： Fischbarg J,Hernandez J,Liebovitch LS,Koniarek JP

更新日期：1985-04-01 00:00:00

abstract：:We studied the effects of a forskolin suspension on intraocular pressure (IOP) in normal albino and pigmented rabbits and in alpha-chymotrypsin induced ocular hypertensive rabbits. Experimental-induced ocular hypertensive rabbits were produced by injecting of alpha-chymotrypsin (167 units) into the posterior chamber o...

journal_title：Current eye research

authors： Shibata T,Mishima H,Kurokawa T

更新日期：1988-07-01 00:00:00

abstract：:Purpose: Dual wavelength retinal oximetry allows the quantification of oxygen saturation in the larger retinal vessels. However, the technique might be refined further by identifying factors that are responsible for the different oxygen saturations in first order arterioles from the same eye shortly after their branch...

journal_title：Current eye research

authors： Jeppesen SK,Bek T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:Anterior ischemic optic neuropathy (AION) is the most common cause of non-glaucomatous optic nerve head (ONH) injury among older adults. AION results from a sudden ischemic insult to the proximal portion of the optic nerve, typically leading to visual impairment. Here, we present an experimental model of photod...

journal_title：Current eye research

authors： Mantopoulos D,Bouzika P,Tsakris A,Pawlyk BS,Sandberg MA,Miller JW,Rizzo Iii JF,Vavvas DG,Cestari DM

更新日期：2016-11-01 00:00:00