Abstract:
PURPOSE:To investigate the spectral content of intraocular pressure (IOP) pulse wave by advanced spectral signal processing of continuous IOP readings obtained by dynamic contour tonometry. PATIENTS AND METHODS:A non-interventional case-control study included 20 healthy subjects, 20 previously untreated primary open angle glaucoma patients, and 20 previously untreated normal tension glaucoma patients. The continuous IOP reading obtained by dynamic contour tonometry was submitted to Fast Fourier Transform signal analysis and further statistical data processing. RESULTS:The spectral components of the IOP pulse wave were discerned up to the fifth harmonic. Highly statistically significant difference was found between the control group and the primary open angle group, and between the primary open angle glaucoma group and the normal tension glaucoma group in the first, second and the third harmonic amplitude (p < 0.01). Glaucoma patients had significantly higher ocular pulse volume values. CONCLUSIONS:It is possible to determine spectral components of the IOP pulse wave up to the fifth harmonic by a spectral analysis of dynamic contour tonometry continuous readings. We found that high Ocular Pulse Amplitude values in primary open angle glaucoma group was associated with high harmonics amplitude, which indicates low rigidity of blood vessels.
journal_name
Curr Eye Resjournal_title
Current eye researchauthors
Božić M,Dukić ML,Stojković Mdoi
10.3109/02713683.2012.700755subject
Has Abstractpub_date
2012-11-01 00:00:00pages
1019-24issue
11eissn
0271-3683issn
1460-2202journal_volume
37pub_type
杂志文章abstract:PURPOSE:To evaluate differences of phagocytic capacities in rat retinal pigment epithelial (RPE) cells, iris pigment epithelial (IPE) cells, and basic fibroblast growth factor (bFGF) cDNA-transfected IPE (bFGF-IPE) cells in vitro. METHODS:The RPE cells and IPE cells were isolated from adult Long Evans rats' eyes. The ...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.23.3.185.5465
更新日期:2001-09-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章,随机对照试验
doi:10.3109/02713683.2013.765487
更新日期:2013-05-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713683.2018.1447674
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:To determine the relative expression of metallothionein isoforms and their differential induction by oxidative stress in cultured RPE cells and to localize the isoforms in the human chorioretinal complex. METHODS:Total RNA was isolated from cultured human retinal pigment epithelial cells using TRI-Reagent. An ...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.24.1.12.5426
更新日期:2002-01-01 00:00:00
abstract::Corneal acidosis has been shown to reduce corneal hydration control (CHC) as measured by the rate, expressed as the percent recovery per hour (PRPH), at which the thickness of the cornea decreases exponentially after an increased hydration load. Since the effect of pH on corneal function is of scientific interest and ...
journal_title:Current eye research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/02713689508999932
更新日期:1995-05-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.27.2.91.15954
更新日期:2003-08-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689309001839
更新日期:1993-07-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688208998376
更新日期:1982-01-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713683.2017.1302591
更新日期:2017-09-01 00:00:00
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journal_title:Current eye research
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更新日期:1994-11-01 00:00:00
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pub_type: 杂志文章
doi:10.3109/02713680903222779
更新日期:2009-11-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689009069929
更新日期:1990-10-01 00:00:00
abstract::Utilizing a rapid colorimetric assay that relates cell number to cytoplasmic hexosaminidase activity, we conducted drug-induced cytotoxicity experiments on human ocular fibroblasts cultured from Tenon's capsule specimens. The effects of two different agents--dimethyl sulfoxide (DMSO) or mitomycin C--on the proliferati...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689008999599
更新日期:1990-06-01 00:00:00
abstract:PURPOSE:To determine whether the usual clinical dose of intravitreal dexamethasone can attenuate intraocular inflammation and retinal necrosis in a rabbit model of fulminant Bacillus cereus endophthalmitis induced by crude exotoxins. METHODS:Thirty-six eyes from pigmented mongrel rabbits received intravitreal injectio...
journal_title:Current eye research
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doi:10.1080/02713680490516701
更新日期:2004-10-01 00:00:00
abstract::Membrane response to the various temperatures as one of the external factors was investigated in the lenses of the poikilothermal animal and the homothermal animal. The rainbow trout lens was used as the poikilothermal material and the rat lens as the homothermal material. The rainbow trout lens maintained in vitro it...
journal_title:Current eye research
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doi:10.3109/02713688509025158
更新日期:1985-04-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713683.2019.1673436
更新日期:2020-04-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689409042392
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:After corneal injury, persistent epithelial defects (PED's) may occur due to the chronic failure of the regenerating epithelium to adhere to the underlying stroma. The aim of this study was to examine the potential of epsilonaminocaproic acid (EACA) as a topical treatment for PED's. EACA inhibits the activation...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.18.2.150.5382
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To establish autologous iris pigment epithelial (IPE) cell transplantation in monkey eyes. METHODS:Autologous IPE cells from three monkeys were obtained by peripheral iridectomy, and cell culture was performed with autologous serum. The cultured cells were labeled with DiI, and transplantation was performed by...
journal_title:Current eye research
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.3109/02713681003760168
更新日期:2010-07-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713680600865052
更新日期:2006-09-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.17.3.308.5225
更新日期:1998-03-01 00:00:00
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pub_type: 杂志文章
doi:10.3109/02713688109001869
更新日期:1981-01-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713680590923276
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:Statins have been shown to reduce ocular inflammation in animal models of uveitis and to prevent development of uveitis in observational studies. There have been no experimental human studies evaluating statins' efficacy and safety in uveitis. In this study, we aimed to investigate efficacy and safety of simvas...
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pub_type: 杂志文章,随机对照试验
doi:10.1080/02713683.2017.1355468
更新日期:2017-12-01 00:00:00
abstract::Four days after corneal inoculation of mice with herpes simplex (type 1) virus (HSV), infected trigeminal ganglion cells with and without calcitonin gene-related peptide (CGRP) antigenicity were examined by electron microscopy in sections treated with colloidal gold labeled antibodies. Cells that contain CGRP were ide...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713689109020354
更新日期:1991-01-01 00:00:00
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journal_title:Current eye research
pub_type: 杂志文章
doi:10.1076/ceyr.19.2.197.5327
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:To investigate the effects of citicoline on upregulated clusterin and retinal damage induced by kainic acid (KA). METHODS:KA was injected into the vitreous of rats. Effects of systemic citicoline treatments were estimated by measuring the thickness of the various retinal layers, immunoblotting, and immunohisto...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.1080/02713680701758719
更新日期:2007-12-01 00:00:00
abstract::Hybridomas producing monoclonal antibodies to the retinal S antigen were obtained by fusion of spleen cells from a BALB/c mouse immunized with purified bovine S antigen and NS-1 myeloma cells. Six cloned hybridomas were selected and expanded as large scale cultures and as ascites in mice. The specificity of the antibo...
journal_title:Current eye research
pub_type: 杂志文章
doi:10.3109/02713688409000800
更新日期:1984-06-01 00:00:00