Collared silicone punctal plugs compared to intracanalicular plugs for the treatment of dry eye.

Abstract:

AIM:To compare collared silicone punctal plugs to intracanalicular SmartPlugs for the treatment of moderate to severe dry eye. MATERIALS AND METHODS:In this prospective, randomized, single blind, clinical study, 30 patients (60 eyes) who had been diagnosed with moderate to severe dry eye syndrome were enrolled. Study group I (n = 30 eyes) received collared silicone punctal plugs and group II (n = 30 eyes) received intracanalicular SmartPlugs. Data for the Schirmer I test, tear break-up time, vital staining, subjective symptoms and frequency of artificial tear application were recorded at baseline and 3 months after punctal occlusion. RESULTS:There was no statistical significant difference for these values between group I and II. CONCLUSIONS:Although published data show free flow with irrigation and probing after SmartPlug insertion, the clinical effect in the treatment of dry eye appears to be the equally well to collared silicone punctal plugs. It seems likely that difference of design and localization between the treatment groups were of minor importance concerning impeding of natural and supplemental moisture.

journal_name

Curr Eye Res

journal_title

Current eye research

authors

Rabensteiner DF,Boldin I,Klein A,Horwath-Winter J

doi

10.3109/02713683.2013.765487

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

521-5

issue

5

eissn

0271-3683

issn

1460-2202

journal_volume

38

pub_type

杂志文章,随机对照试验
  • Relationship between Aquaporin-1 Protein Expression and Choroidal Thickness during the Recovery of Form-deprivation Myopia in Guinea Pigs.

    abstract::Purpose: The purpose of this study was to investigate the relationship between aquaporin-1 (AQP-1) protein expression in the choroid and choroid thickness (CT) during the recovery of form-deprivation (FD) myopia in guinea pigs.Materials and Methods: Seventy-two guinea pigs were randomly assigned to the normal control ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2019.1689275

    authors: Chen W,Zhang H,Zhang Y,Wang Q,Wang Y,Li ZW

    更新日期:2020-06-01 00:00:00

  • Optical effects of UV-A and UV-B radiation on the cultured bovine lens.

    abstract::The effects of repeated exposures to UV-A (335 nm) and UV-B (305 nm) radiation on the crystalline lens were studied by treating cultured bovine lenses daily or weekly. The effects of irradiation on lens optical quality were monitored using an automated scanning laser system that records both relative transmittance and...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689409167301

    authors: Stuart DD,Cullen AP,Sivak JG,Doughty MJ

    更新日期:1994-05-01 00:00:00

  • Transforming growth factor-beta stimulates collagen and fibronectin synthesis by human corneal stromal fibroblasts in vitro.

    abstract::The effects of transforming growth factor-beta (TGF beta) and epidermal growth factor (EGF) on the synthesis of collagen and fibronectin, and on the proliferation of human corneal stromal fibroblasts in vitro, were evaluated. Human corneal stromal fibroblasts in culture were incubated for 48 hours with TGF beta or EGF...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689308995765

    authors: Ohji M,SundarRaj N,Thoft RA

    更新日期:1993-08-01 00:00:00

  • Interleukin (IL)-17A Promotes Angiogenesis in an Experimental Corneal Neovascularization Model.

    abstract:PURPOSE:To explore the roles of interleukin (IL)-17A in alkali-induced corneal neovascularization (CRNV). METHODS:Induction of CRNV by alkali injury was performed and compared in recombinant mouse IL-17A protein or anti-mouse IL-17A neutralizing antibody (Ab)-treated mice. The expression of IL-17A, IL-17A receptor (IL...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2016.1196705

    authors: Liu G,Wu H,Lu P,Zhang X

    更新日期:2017-03-01 00:00:00

  • Characterization of active and passive Na+ and K+ transport in normal rat lens by the short-circuiting technique.

    abstract::An initial characterization of the lenticular ionic permeabilities of the isolated Sprague-Dawley rat lens utilizing short-circuiting techniques was carried out to provide the basis for further studies of mechanisms underlying cataractogenesis associated with salt-sensitive genetic hypertension in the rat. Both active...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689209000070

    authors: Estapé ES,Rodríguez-Sargent C,Candia OA

    更新日期:1992-02-01 00:00:00

  • Ultrastructural and acid phosphatase histochemical analysis of developmental lens abnormalities in rats with X-ray-induced cataract mutation.

    abstract::Lenses from normal Wistar rats and those from a Wistar strain with X-ray-induced cataract mutation were examined electron microscopically for morphological characterization and acid phosphatase (AcPase) localization. Ocular anlages of 11 through 18 days of gestation were included in the study. A late-separating or per...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688409003064

    authors: Anderson JW,Gorthy WC

    更新日期:1984-04-01 00:00:00

  • Association of changes in intracellular cyclic AMP with changes in phagocytosis in cultured rat pigment epithelium.

    abstract::Papavarine, cholera toxin, and isoproterenol each elevated cyclic AMP in cultured rat retinal pigment epithelium and reduced the phagocytosis of isolated rod outer segments (38-66% of controls) during a 4 hour incubation. In addition, cultured pigment epithelium was preincubated with 25 mM exogenous cyclic AMP for two...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688608995161

    authors: Edwards RB,Flaherty PM

    更新日期:1986-01-01 00:00:00

  • Apoptosis and cell proliferation in proliferative retinal disorders: PCNA, Ki-67, caspase-3, and PARP expression.

    abstract:PURPOSE:To assess the incidence of cell proliferation and apoptosis in epiretinal membranes from eyes with proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy (PDR), and macular pucker (MP) and to further investigate the potential involvement of key executors of apoptosis. METHODS:Epiretinal memb...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680590956306

    authors: Zhang X,Barile G,Chang S,Hays A,Pachydaki S,Schiff W,Sparrow J

    更新日期:2005-05-01 00:00:00

  • Unoprostone isopropyl rescues retinal progenitor cells from apoptosis in vitro.

    abstract:PURPOSE:Unoprostone isopropyl is an ocular hypotensive that was originally produced as a prostaglandin F2alpha analogue and is eventually recognized as a synthetic docosanoid. The compound is recently suggested to have potent neuroprotective ability in the retina. The purpose of this study is to test whether and how th...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680490889465

    authors: Mukuno H,Nakamura M,Kanamori A,Nagai A,Negi A,Seigel G

    更新日期:2004-12-01 00:00:00

  • Steroid inhibition of limbal blood and lymphatic vascular cell growth.

    abstract::Steroids are widely used in the prevention of corneal neovascularization in a wide range of natural and experimental situations. However, no information is available on their effect on the growth of the individual limbal blood vascular cells or of lymphatic cells involved in corneal neovascularization. In addition, tr...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689508999908

    authors: Boneham GC,Collin HB

    更新日期:1995-01-01 00:00:00

  • In Vivo Efficacy of Histatin-1 in a Rabbit Animal Model.

    abstract::Purpose/Aim: Corneal abrasions and nonhealing corneal epithelial defects are common conditions that cause pain and sometimes are slow to heal. Histatins, a family of histidine-rich peptides, have been implicated in oral and skin epithelial wound healing, and have been shown to be effective in vitro in human corneal ep...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1490772

    authors: Oydanich M,Epstein SP,Gadaria-Rathod N,Guers JJ,Fernandez KB,Asbell PA

    更新日期:2018-10-01 00:00:00

  • Quantitative comparison of fluoroquinolone therapies of experimental gram-negative bacterial keratitis.

    abstract:PURPOSE:To determine the effectiveness of topically applied fluoroquinolones for experimental Pseudomonas or Serratia keratitis. METHODS:Bacteria were injected intrastromally (10(3) colony forming units [CFU]). From 16 to 22 hours post-infection (PI), a single topical drop of moxifloxacin (Vigamox, 0.545%), levofloxac...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.28.5.337.28676

    authors: Thibodeaux BA,Dajcs JJ,Caballero AR,Marquart ME,Girgis DO,O'Callaghan RJ

    更新日期:2004-05-01 00:00:00

  • Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients.

    abstract::Purpose: To investigate to what extent the OSDI can be utilized as a discriminative test for clinical findings. Methods: One thousand and ninety patients with dry eye disease (DED) were consecutively included and examined for osmolarity, tear film break-up time (TFBUT), ocular protection index (OPI), ocular surface st...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2019.1604972

    authors: Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Hua Y,Eidet JR,Stojanovic A,Dartt DA,Utheim TP

    更新日期:2019-09-01 00:00:00

  • Visual and Refractive Outcomes with a New Topography-integrated Wavefront-guided Lasik Procedure.

    abstract:PURPOSE:To evaluate the clinical outcomes of laser in situ keratomileusis (LASIK) using a new approach for the calculation of the ablation profile based on wavefront vertexing from pupil plane to corneal. METHODS:One hundred eyes of 50 patients (age, 21-41 years) with low and moderate myopia were enrolled in this pros...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2020.1822418

    authors: Uceda-Montañés A,Rogers M,Piñero DP

    更新日期:2020-09-16 00:00:00

  • Post-ischemia ERG recovery is influenced by temperature.

    abstract::In experimental work on retinal ischemia and its medical management, we have been disturbed by the large variations in the electroetinogram (ERG) recovery of rabbit eyes subjected to similar degrees of ischemia. We investigated whether body temperature might be one of the critical factors. We studied pigmented Dutch r...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689508999918

    authors: Nayak MS,Marmor MF

    更新日期:1995-02-01 00:00:00

  • Lipid synthesis in the bovine lens.

    abstract::Lipid synthesis was investigated in bovine lens in organ culture for 9 hours using 14C acetate as a precursor. The greatest incorporation occurred in phospholipid fraction with phosphatidyl choline being the major phospholipid labeled. Considerable activity was incorporated in the free fatty acid fraction, cholesterol...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688709034889

    authors: Albers-Jackson B,Nga Do A

    更新日期:1987-09-01 00:00:00

  • C5a receptor-mediated production of IL-8 by the human retinal pigment epithelial cell line, ARPE-19.

    abstract:PURPOSE:C5a anaphylatoxin is a potent inflammatory mediator that acts on polymorphonuclear cells (PMN) and monocytes via C5a receptors (C5aR). It mediates chemotaxis of both cell types and stimulates cytokine release from the latter. To investigate whether C5a can act on retinal pigment epithelial (RPE) cells, we exami...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.23.5.320.5437

    authors: Fukuoka Y,Medof EM

    更新日期:2001-11-01 00:00:00

  • Efficacy of the Inverted Internal Limiting Membrane Flap Technique with Perfluorocarbon Liquid-Mediated Selective Staining for Large Macular Hole Repair.

    abstract:PURPOSE:The aim of the present study was to evaluate the efficacy of the inverted internal limiting membrane (ILM) flap technique that involved the use of a perfluorocarbon liquid (PFCL) bubble for the selective prevention of indocyanine green (ICG) staining of the parts of the inverted flap in contact with the retinal...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1524014

    authors: Ra H,Lee WK

    更新日期:2019-01-01 00:00:00

  • Using an in vitro model of lipid deposition to assess the efficiency of hydrogen peroxide solutions to remove lipid from various contact lens materials.

    abstract:PURPOSE:To test the ability of two commercially available hydrogen peroxide disinfection solutions, one containing a surfactant and one without, to remove lipid from various contact lens materials using in vitro radiochemical experiments. METHODS:Etafilcon A, senofilcon A and balafilcon A contact lens materials were i...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2012.682636

    authors: Lorentz H,Heynen M,Tran H,Jones L

    更新日期:2012-09-01 00:00:00

  • Protein kinase C-mediated regulation of matrix metalloproteinase and tissue inhibitor of metalloproteinase production in a human retinal müller cells.

    abstract:PURPOSE:Matrix metalloproteinases (MMPs) play an important role in the degradation of extracellular matrix (ECM) proteins in the retina. Breakdown of ECM proteins results in neovascularization and tractional retinal detachment, which eventually lead to the symptoms of proliferative diabetic retinopathy. Müller cells ar...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2012.682635

    authors: Miyata Y,Kase M,Sugita Y,Shimada A,Nagase T,Katsura Y,Kosano H

    更新日期:2012-09-01 00:00:00

  • Matrix metalloproteinases and metalloproteinase inhibitors in human interphotoreceptor matrix and vitreous.

    abstract:PURPOSE:We wished to establish which matrix metalloproteinases (MMPs) and metalloproteinase inhibitors (TIMPs) were present in human interphotoreceptor matrix (IPM) and vitreous. METHODS:IPM and vitreous were obtained from postmortem human eyebank eyes. Western immunoblots were probed with antibodies against human MMP...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.17.2.132.5610

    authors: Plantner JJ,Smine A,Quinn TA

    更新日期:1998-02-01 00:00:00

  • Rose bengal induced corneal swelling: relation to inciting wavelength.

    abstract::Cornea endothelial cells sensitized with rose bengal and exposed to light demonstrated a wavelength dependent alteration in physiological response. Corneas exposed to 549 millimicron swelled at rates similar to controls exposed to identical energy levels of incandescent light. Corneas exposed to 451, 500, 612, and 651...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688109019990

    authors: Hull DS,Csukas S,Green K

    更新日期:1981-01-01 00:00:00

  • Matricellular Proteins Play a Potential Role in Acute Primary Angle Closure.

    abstract:PURPOSE:To quantify levels of matricellular proteins in aqueous humor samples from acute primary angle closure (APAC) and non-glaucomatous cataract eyes and investigate their correlation with intraocular pressure (IOP) fluctuation. MATERIALS AND METHODS:Aqueous humor samples were collected from 63 eyes including 29 cu...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1449222

    authors: Wang J,Fu M,Liu K,Wang N,Zhang Z,Zhou M,Xu X

    更新日期:2018-06-01 00:00:00

  • Meibomian gland dropout in patients with dry eye disease in China.

    abstract:PURPOSE:To examine the morphological changes in the meibomian glands of eyes of patients with dry eye disease using the non-contact infrared meibography system and to assess their relationship with meibomian dropout, signs, and tear-film function. METHODS:Subjects included 264 randomly selected patients (528 eyes) suf...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2014.891748

    authors: Feng Y,Gao Z,Feng K,Qu H,Hong J

    更新日期:2014-10-01 00:00:00

  • Phototoxicity of chlorpromazine on retinal pigment epithelial cells.

    abstract::As it is known that chlorpromazine (CPZ) can bind to melanins as well as cause ocular phototoxicity, we investigated the cytotoxic effects of UV-visible irradiation of melanotic and amelanotic retinal pigment epithelial (RPE) cells in the presence of CPZ. At low concentrations (5 micrograms/ml) of CPZ a photosensitiza...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688809047014

    authors: Persad S,Menon IA,Basu PK,Carre F

    更新日期:1988-01-01 00:00:00

  • The combined effect of diabetes and ionising radiation on the retinal vasculature of the rat.

    abstract::The clinical impression that pre-existing diabetes exacerbates radiation injury to the retinal vasculature was studied in STZ diabetic rats. Half of 2 groups of streptozotocin (STZ)-induced diabetic rats and 1 group of normal animals had their right eyes irradiated with 1000 cGy of 90 KVP x-rays. The prevalence of ace...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689309029227

    authors: Gardiner TA,Amoaku WM,Archer DB

    更新日期:1993-11-01 00:00:00

  • Formation of cholesterol Bilayer Domains Precedes Formation of Cholesterol Crystals in Membranes Made of the Major Phospholipids of Human Eye Lens Fiber Cell Plasma Membranes.

    abstract::Purpose/Aim: The goal of this study is to reveal how age-related changes in phospholipid (PL) composition in the fiber cell plasma membranes of the human eye lens affect the cholesterol (Chol) content at which Chol bilayer domains (CBDs) and Chol crystals start to form.Materials and Methods: Saturation-recovery electr...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2019.1662058

    authors: Mainali L,Pasenkiewicz-Gierula M,Subczynski WK

    更新日期:2020-02-01 00:00:00

  • Variability of retinal steepness at the posterior pole in children 7-15 years of age.

    abstract:PURPOSE:Considerable evidence suggests that both axial and peripheral refraction play important roles in eye growth control. The large variability in peripheral refraction seen in adults and children indicates that the peripheral retina is exposed to a wide range of refractive errors. The current lack of appropriate me...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.27.2.61.15454

    authors: Schmid GF

    更新日期:2003-07-01 00:00:00

  • Sodium/potassium ATPase in normal and cataractous human lenses.

    abstract::Na/K ATPase activity has been determined in normal and cataractous human lenses using labeled ATP as a substrate. The enzyme is distributed throughout the lens with approximately 1/3 of the total activity in the capsule-epithelium and 1/2 of the activity in the cortex. Furthermore, the activity of Na/K ATPase decrease...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688209000778

    authors: Kobatashi S,Roy D,Spector A

    更新日期:1982-01-01 00:00:00

  • Efficacy of Purtscher's Retinopathy Treatments: A Systematic Review.

    abstract:OBJECTIVE:The aim of this review is to evaluate the efficacy of available Purtscher's Retinopathy treatments. MATERIALS AND METHODS:In order to collect single-case reports, electronic searches were conducted in several databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, SinoMed...

    journal_title:Current eye research

    pub_type: 杂志文章,评审

    doi:10.1080/02713683.2016.1255335

    authors: Xia D,Chen X,Zhou Q,Xiao S,Yu Y,Wang Y,Du G,Huang H,Zhang W,Chen Y

    更新日期:2017-06-01 00:00:00