Quantitative comparison of fluoroquinolone therapies of experimental gram-negative bacterial keratitis.

abstract：PURPOSE:Both HSV-1 and HSV-2 express LAT during viral latency. Previous studies indicated that deletion of either LAT impairs viral reactivation from latency, but that the HSV-1 LAT confers the ability to reactivate efficiently from trigeminal ganglia onto HSV-2. We sought to determine whether the HSV-2 LAT could funct...

journal_title：Current eye research

authors： Hill J,Patel A,Bhattacharjee P,Krause P

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Modern refractive surgery and follow up relies on a knowledge of corneal thickness (CT) and shape, and the reliability of modern instrumentation providing such data is important. This study sought to determine the performance of the TOPCON SP-2000P specular microscope in measuring CT. The aims of this study wer...

journal_title：Current eye research

authors： Cho P,Cheung SW

更新日期：2000-10-01 00:00:00

abstract：PURPOSE/AIM OF THE STUDY:The aim of this study is to investigate the effect of pseudoexfoliation (PEX) and PEX-induced dry eye on central corneal thickness (CCT). MATERIALS AND METHODS:This cross-sectional study consists of total 270 eyes of 135 patients (67 females, 68 males) in total. After excluding the PEX (-) 32 ...

journal_title：Current eye research

authors： Akdemir MO,Kirgiz A,Ayar O,Kaldirim H,Mert M,Cabuk KS,Taskapili M

更新日期：2016-01-01 00:00:00

abstract：:Phosphorylated proteins of the chick lens were identified following incubation of lenses in a medium containing 32P and subsequent analysis by gel electrophoresis. The acidic variant of the vimentin and both subunits of fodrin were phosphorylated, as were the 95 Kd and 49 Kd proteins associated with the beaded-chain f...

journal_title：Current eye research

authors： Ireland M,Maisel H

更新日期：1984-07-01 00:00:00

abstract：PURPOSE:Histidine is an indispensable amino acid with an imidazole ring and it is a precursor of histamine, carnosine, and anserine. Histidine has been proposed to act as a neurotransmitter or neuromodulator in mammalian central nervous system (CNS), including retina. In this study, we report histidine-like immunoreact...

journal_title：Current eye research

authors： Kusakari Y,Nishikawa S,Ishiguro S,Tamai M

更新日期：1997-06-01 00:00:00

abstract：PURPOSE:To explore the in vitro proliferative potential of human limbal epithelial cells after 31 degrees C organ-culture storage and to investigate putative factors influencing it. METHODS:185 cultures of limbal explants were carried-out either from full-thickness explants (n = 102) or from enzymatically dissociated ...

journal_title：Current eye research

authors： Zito-Abbad E,Borderie VM,Baudrimont M,Bourcier T,Laroche L,Chapel C,Uzel JL

更新日期：2006-05-01 00:00:00

abstract：:The morphology and postnatal ontogeny of the major pathway for aqueous outflow in the canine eye has been examined. Normal canine chamber angles of the Beagle at one day, one through ten weeks, three, four and six months, and one and two years of age were used. Angle tissue was prepared and examined by standard techni...

journal_title：Current eye research

authors： Samuelson DA,Gelatt KN

更新日期：1984-06-01 00:00:00

abstract：:Purpose: To evaluate the effect of isolated oblique muscle weakening on horizontal deviation in patients with A- and V-pattern exotropia.Methods: The medical records of patients who underwent bilateral oblique muscle weakening for A- and V-pattern exotropia associated oblique muscle overaction between 2011 and 2018 we...

journal_title：Current eye research

authors： Wang X,Zhang W,Liu L

更新日期：2020-02-01 00:00:00

abstract：:Macrophages are invariably present in the intraocular membranes of patients with traumatic proliferative vitreoretinopathy (PVR). There are two sources from which these macrophages could be recruited: adjacent tissues and the systemic circulation. In the study described herein, the role of circulating white blood cell...

journal_title：Current eye research

authors： Gabrielian K,Wang HM,Lee M,Ogden TE,Ryan SJ

更新日期：1994-01-01 00:00:00

abstract：:In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid mice (c57BL/6J-Pa/Pa), and those of littermate black mice (C57BL/6J-+/Pa) were examined ultrastructurally, histochemically, and biochemically. As controls, the eyes of black and congenic albino mice (C57BL/6J +/C2J and -C2J...

journal_title：Current eye research

authors： Ito M,Hashimoto K,Organisciak DT

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:The purpose was to investigate the effect of the superoxide dismutase mimetic tempol on decreases in retinal blood flow that are found in diabetic mice. MATERIALS AND METHODS:Streptozotocin (STZ) was injected into male C57BL/6 mice to induce hyperglycemia. One week following the STZ injection, subsets of the m...

journal_title：Current eye research

authors： Yadav AS,Harris NR

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To examine the effects of calcitonin gene-related peptide (CGRP) on intraocular pressure (IOP). METHODS:IOP was periodically measured in rabbits treated with intravitreal injection (20 ael) of either: 1) CGRP (10(-4) approximately 10(-7) M) into one eye; 2) CGRP (10(-4) or 10(-6) M) into both eyes 30 min after...

journal_title：Current eye research

authors： Taniguchi T,Nakai Y,Karim Z,Gu ZB,Kawase K,Kitazawa Y

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear production. METHODS:Patients (n = 1090) with DED of different etiologies received an extensive dry e...

journal_title：Current eye research

authors： Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Lagali N,Stojanovic A,Dartt DA,Utheim TP

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of intravitreal (IV) triamcinolone acetonide (IVTA) versus subtenon (ST) triamcinolone acetonide (STTA) injection for the treatment of diabetic macular edema (DME). METHODS:Searches for randomized clinical trials published between 1 January 1950 and 15 March 2011 were conducted using ...

journal_title：Current eye research

authors： Qi HP,Bi S,Wei SQ,Cui H,Zhao JB

更新日期：2012-12-01 00:00:00

abstract：:Purpose: To evaluate the effect of methylphenidate on visual field testing in healthy adults with abnormal visual field results. Methods: This prospective, randomized, controlled interventional clinical trial comprised all patients who had abnormal visual field test results and normal eye examination and ophthalmic hi...

journal_title：Current eye research

authors： Sternfeld A,Bialer OY,Keidar D,Megiddo E,Budnik I,Stiebel-Kalish H,Livnat T

更新日期：2020-12-21 00:00:00

abstract：PURPOSE:To evaluate choroidal thickness (CT) and retinal morphological changes in eyes with neovascular age-related macular degeneration (nAMD) following ranibizumab or aflibercept intravitreal treatment. MATERIALS AND METHODS:This was a prospective, observational, comparative study where 76 eyes of 76 consecutive pat...

journal_title：Current eye research

authors： Gharbiya M,Giustolisi R,Marchiori J,Bruscolini A,Mallone F,Fameli V,Nebbioso M,Abdolrahimzadeh S

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate macular ganglion cell complex (GCC) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in patients treated with SSRIs. METHODS:The present study included 62 eyes of 31 patients who were using SSRIs and 60 eyes of 30 healthy, age- and gender-matched control subjects. All patients...

journal_title：Current eye research

authors： Guclu H,Gorgulu Y,Gurlu VP,Kose Cinar R,Ozal SA,Çaliyurt O

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Based on the relationship between keratoconus and dry eye, the aim of this study was to evaluate changes in signs and symptoms of dry eye in keratoconus patients before and after intrastromal corneal ring surgery. METHODS:Fifteen keratoconus patients were enrolled in Fundación Jiménez-Díaz of Madrid and Univer...

journal_title：Current eye research

authors： Carracedo G,Recchioni A,Alejandre-Alba N,Martin-Gil A,Batres L,Morote IJ,Pintor J

更新日期：2017-04-01 00:00:00

abstract：PURPOSE:To evaluate the length of the trabecular meshwork (TM) from the scleral spur (SS) to Schwalbe's line (SL) and assess the detectability of the SS in histopathology specimens. METHODS:This study included 158 angle images from 79 cross-sectional slides derived from eyes enucleated for melanoma. The slides were st...

journal_title：Current eye research

authors： Kasuga T,Chen YC,Bloomer MM,Hirabayashi KE,Hiratsuka Y,Murakami A,Lin SC

更新日期：2013-01-01 00:00:00

abstract：:Purpose/Aim: Many genes have been associated with primary open-angle glaucoma (POAG). Knowing exactly where they are expressed in the eye helps to unravel POAG pathology and to select optimal targets for intervention. We investigated whether RNA in situ hybridization (RNA-ISH) is a convenient technique to obtain detai...

journal_title：Current eye research

authors： Hubens WHG,Breddels EM,Walid Y,Ramdas WD,Webers CAB,Gorgels TGMF

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:This study identifies the prevalence and risk factors of sensorineural hearing loss and primary open-angle glaucoma (POAG). MATERIALS AND METHODS:Patients aged 19 years or older who had undergone both ophthalmologic examination and audiometry as part of the Korea National Health and Nutrition Examination Surve...

journal_title：Current eye research

authors： Kim JM,Lee MY,Kim JW,Lee J,Kim HJ,Cha SC,Kim NR

更新日期：2020-08-01 00:00:00

abstract：:The aim of this study was to determine whether or not alpha neoprotein formation can occur in the lens in response to a photolytic process. Alpha crystallin from young calf and aged bovine lenses was irradiated for up to 22 hours with UV light. After cortical alpha crystallin had been irradiated, it completely preserv...

journal_title：Current eye research

authors： Hibino K,Du J,Dillon J,Malinowski K

更新日期：1988-11-01 00:00:00

abstract：:The clinical impression that pre-existing diabetes exacerbates radiation injury to the retinal vasculature was studied in STZ diabetic rats. Half of 2 groups of streptozotocin (STZ)-induced diabetic rats and 1 group of normal animals had their right eyes irradiated with 1000 cGy of 90 KVP x-rays. The prevalence of ace...

journal_title：Current eye research

authors： Gardiner TA,Amoaku WM,Archer DB

更新日期：1993-11-01 00:00:00

abstract：PURPOSE:Recent studies have shown that the levels of interleukin (IL)-1beta, IL-6 and IL-8 are associated with the severity of infectious diseases. The purpose of this study was to investigate whether IL-1beta regulates the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colo...

journal_title：Current eye research

authors： Xue ML,Zhu H,Willcox M,Wakefield D,Lloyd A,Thakur A

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:This study was carried out in order to determine the most potent and novel uveitopathogenic sites of recoverin using synthetic peptides. METHODS:Several synthetic peptides containing the recoverin sequence plus adjuvants were injected into Lewis rats, and the uveitopathogenic sequence was defined, clinically, ...

journal_title：Current eye research

authors： Ohkoshi M,Abe T,Satoh N,Nakajima A,Sakuragi S

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:This study was designed to investigate whether synthetic small interference RNA (siRNA) targeting VEGF-A could inhibit mouse corneal neovascularization or not. METHODS:First, the effect of synthetic siRNA targeting VEGF-A on the expression of VEGF in human retinal pigment epithelial line ARPE-19 cells was exam...

journal_title：Current eye research

authors： Zuo L,Fan Y,Wang F,Gu Q,Xu X

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Klotho genes are expressed in limited tissues and have been found to be a pathogenic factor of age-related diseases in mammals, but their expressions and functions in human eyes are yet to be defined. This study was performed to investigate the expression of Klotho family genes in human ocular tissues and anter...

journal_title：Current eye research

authors： Zhang Y,Wang L,Wu Z,Yu X,Du X,Li X

更新日期：2017-06-01 00:00:00

abstract：:Antifibrosis agents have improved the success of glaucoma filtration surgery, although undesired side effects are not readily reversible and may present a major limitation in the use of these agents. Our purpose was to study the efficacy of cytosine arabinoside (Ara-C) as an adjunctive antimetabolite in glaucoma surge...

journal_title：Current eye research

authors： Chu JL,Shields SR,Netland PA

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:To study the effect of Na-K pump and K(ATP) channel inhibition on the diameter and the adenosine-induced vasodilation of small retinal arterioles. METHODS:Thirty isolated porcine arterioles with a diameter of approximately 70 microm were mounted in a double-barrelled pipette system placed in an organ bath, and...

journal_title：Current eye research

authors： Jeppesen P,Aalkjaer C,Bek T

更新日期：2002-07-01 00:00:00

abstract：:With Golgi impregnation, a simple amacrine cell type is described in the chick retina. The most relevant morphological feature of these retinal neurons is a single straight, radial trunk which dichotomizes tangentially in a rectilinear expansion in the 5th stratum of the inner plexiform layer (IPL). ...

journal_title：Current eye research

authors： Genis-Galvez JM,Chmielewski CE,Prada FA

更新日期：1989-02-01 00:00:00