Aqueous outflow in the beagle. II. Postnatal morphologic development of the iridocorneal angle: corneoscleral trabecular meshwork and angular aqueous plexus.

abstract：:Serum zinc and copper levels were analyzed in 26 retinitis pigmentosa patients and compared with serum zinc levels of a control group. Serum zinc levels were documented to be decreased with a mean concentration of 0.735 +/- 0.167 micrograms/ml (p less than 0.001). Serum copper levels, on the other hand, were found to ...

journal_title：Current eye research

authors： Karcioglu ZA,Stout R,Hahn HJ

更新日期：1984-08-01 00:00:00

abstract：PURPOSE:To compare the efficacy and tolerability of diclofenac and bromfenac ophthalmic solutions as adjunctive therapy after cataract surgery. MATERIALS AND METHODS:This prospective randomized controlled study included 130 patients who underwent cataract surgery. One hundred patients were randomized to receive postop...

journal_title：Current eye research

authors： Giannaccare G,Finzi A,Sebastiani S,Greco F,Versura P,Campos EC

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear production. METHODS:Patients (n = 1090) with DED of different etiologies received an extensive dry e...

journal_title：Current eye research

authors： Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Lagali N,Stojanovic A,Dartt DA,Utheim TP

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To investigate whether zeaxanthin, the predominant carotenoid pigment of the macular pigments in human retina, provides neuroprotection against retinal cell damage. METHODS:We used in vitro cultured retinal ganglion cells (RGCs), specifically RGC-5, an E1A virus-transformed rat cell line. Cell damage was induc...

journal_title：Current eye research

authors： Nakajima Y,Shimazawa M,Otsubo K,Ishibashi T,Hara H

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:The prospective study evaluated the effects of optical defocus on kinetic sensitivity using automated kinetic perimetry. MATERIALS AND METHODS:The 17 eyes of 17 healthy young participants were evaluated. All of the participants had myopia (≥ -5.00 D) and mild to no astigmatism (<1.00 D). Automated kinetic peri...

journal_title：Current eye research

authors： Hirasawa K,Shoji N

更新日期：2015-01-01 00:00:00

abstract：:Purified Pseudomonas aeruginosa elastase cleaved a 65 kDa gelatinase [inactive proenzyme form of matrix metalloproteinase (MMP-2)] from human corneal fibroblasts into a biologically active fragment with an approximate molecular mass of 58 kDa. However, purified pseudomonal alkaline protease did not cleave MMP-2 apprec...

journal_title：Current eye research

authors： Matsumoto K,Shams NB,Hanninen LA,Kenyon KR

更新日期：1992-11-01 00:00:00

abstract：:Four groups of BALB/c mice were treated locally with different concentrations (0.1-1.0%) of retinoic acid (Etretinate) ointment for a period of one to four weeks. A fifth group was treated with the ointment base only. Ia-positive dendritic cells were identified by an indirect immunofluorescence technique which was con...

journal_title：Current eye research

authors： Kremer I,Gabai U,Arbizo M,Arbizo V,Laibson PR

更新日期：1995-03-01 00:00:00

abstract：:In these experiments we characterize rabbit and bovine corneal endothelia cell cultured on microporous membrane filters (0.6cm2). Cell cultured bovine or rabbit corneal endothelial cells (subcultures 1-3) were seeded onto Millicell-HA filter inserts. Electrical resistance measured across the cultured monolayers increa...

journal_title：Current eye research

authors： Geroski DH,Hadley A

更新日期：1992-01-01 00:00:00

abstract：:Posterior vitreous detachment (PVD) and epiretinal membranes occur in a number of vitreoretinal diseases. We have developed an experimental model in which we can provide the morphologic correlation of these dynamic processes. The method provides the opportunity to study epiretinal membrane formation with the scanning ...

journal_title：Current eye research

authors： Matsumoto B,Hsu HT,Blanks JC,Ryan SJ

更新日期：1986-04-01 00:00:00

abstract：:The intraocular inflammatory reaction in a murine model of herpes simplex keratouveitis was studied using immunohistochemical techniques. 5 x 10(5) PFU of HSV-1 (Stewart strain) was applied to the abraded cornea of BALB/c mice. The subsequent development of keratouveitis was documented by sequential examination, conve...

journal_title：Current eye research

authors： Wang HM,Sheu MM,Stulting RD,Kaplan HJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:There is a clinical need for biomimetic corneas that are as effective, preferably superior, to cadaveric donor tissue. Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native matrix ultrastructure and intrinsic biological cues including growth fac...

journal_title：Current eye research

authors： Wilson SL,Sidney LE,Dunphy SE,Dua HS,Hopkinson A

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:Pseudoexfoliation (PXF) is a microfibrillopathy involving disordered elastogenesis. Abnormal extracellular matrix (ECM) production underlies the pathophysiology of PXF. The enzyme Lysyl oxidase (LOX) and its isoforms are known to cross-link the elastin and collagen. Though the etiopathogensis of PXF is not well...

journal_title：Current eye research

authors： Gayathri R,Coral K,Sharmila F,Sripriya S,Sripriya K,Manish P,Shantha B,Ronnie G,Vijaya L,Narayanasamy A

更新日期：2016-10-01 00:00:00

abstract：:Purpose/Aim: Many genes have been associated with primary open-angle glaucoma (POAG). Knowing exactly where they are expressed in the eye helps to unravel POAG pathology and to select optimal targets for intervention. We investigated whether RNA in situ hybridization (RNA-ISH) is a convenient technique to obtain detai...

journal_title：Current eye research

authors： Hubens WHG,Breddels EM,Walid Y,Ramdas WD,Webers CAB,Gorgels TGMF

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To study the efficacy and outcomes of short-term postoperative vitreoretinal tamponade with perfluorocarbon heavy liquid in patients with giant retinal tear. MATERIALS AND METHODS:The study group consisted of 13 consecutive patients (13 eyes) who presented with giant retinal tear at a tertiary medical center i...

journal_title：Current eye research

authors： Eiger-Moscovich M,Gershoni A,Axer-Siegel R,Weinberger D,Ehrlich R

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:Corneal autofluorescence is related to advanced glycation end products formed by glucose that reaches the cornea via the aqueous humour. The aim of the study was to examine the influence on autofluorescence of changes in permeability of the blood aqueous barrier. METHODS:Corneal autofluorescence was measured i...

journal_title：Current eye research

authors： Kessel L,Moldow B,van Best JA,Sander B

更新日期：2003-05-01 00:00:00

abstract：:Severe retinopathy of prematurity (ROP) occurs in the smallest and sickest of premature infants. We hypothesized that, in a rat model of oxygen induced retinopathy, abnormal neovascularization would occur more frequently in larger litters where the pups are subject to postnatal growth retardation. Four litters of newb...

journal_title：Current eye research

authors： Holmes JM,Duffner LA

更新日期：1996-04-01 00:00:00

abstract：PURPOSE/AIMS:To evaluate the prognostic factors for the best corrected visual acuity (BCVA) and central subfield macular thickness (CSMT) after vitrectomy with internal limiting membrane (ILM) peeling for diabetic macular edema. MATERIALS AND METHODS:A total of 44 eyes of 35 patients who had undergone vitrectomy with ...

journal_title：Current eye research

authors： Yamada Y,Suzuma K,Ryu M,Tsuiki E,Fujikawa A,Kitaoka T

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Choroidal neovascularization (CNV) is a major cause of vision loss in patients with age-related macular degeneration (AMD). Stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) plays a critical role in homing of bone marrow-derived cells (BMCs) to choroidal neovascularization (CNV). In this st...

journal_title：Current eye research

authors： Zhang ZX,Wang YS,Shi YY,Hou HY,Zhang C,Cai Y,Dou GR,Yao LB,Li FY

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:Matrix metalloproteinases (MMPs) are involved in posterior capsule opacification (PCO), but the mechanisms that promote MMP expression are yet to be determined. In this study, we investigated whether type I collagen, which is only detected in aged or cataractous lens capsules, affects the expression and activat...

journal_title：Current eye research

authors： Shimada A,Miyata Y,Kosano H

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the functional connectivity between the primary visual cortex and other cortical areas during rest in normal subjects and patients with comitant strabismus using functional magnetic resonance imaging (fMRI). METHODS:A prospective, observational study was conducted. Ten pati...

journal_title：Current eye research

authors： Yan X,Wang Y,Xu L,Liu Y,Song S,Ding K,Zhou Y,Jiang T,Lin X

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To determine the role of matrix metalloproteinase 9 (MMP9) in advanced glycation end-products (AGEs) induced damage to blood-retinal barrier (BRB) and the therapeutic effects of minocycline, an MMP inhibitor, against the BRB damages. METHODS:Forty-eight Sprague Dawley rats were randomly assigned to 3 groups (1...

journal_title：Current eye research

authors： Chen YD,Xu X,Xia X,Wu H,Liu K,Zheng Z,Zhu D

更新日期：2008-11-01 00:00:00

abstract：:The goal of this study was to determine the effect of extracellular matrix components on the phagocytic function of the retinal pigment epithelial (RPE) cell. Cultured human fetal RPE cells were established in culture and plated on three commercially-prepared substrates: collagen IV, fibronectin and laminin and on thr...

journal_title：Current eye research

authors： Miceli MV,Newsome DA

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Retinal ischemia and neovascularization (NV) are important components of many retinal disorders. To facilitate further investigation of retinal ischemia and neovascularization, we sought to develop a reproducible in vivo experimental model of venous occlusion by photodynamic thrombosis in rats. METHODS:After a...

journal_title：Current eye research

authors： Saito Y,Park L,Skolik SA,Alfaro DV,Chaudhry NA,Barnstable CJ,Liggett PE

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to report on the evaluation of corneal nerve fiber density and corneal sensation after accelerated corneal collagen cross-linking on keratoconus patients. METHODS:The study was performed on 30 keratoconus eyes (30 participants: 16 M, 14 F; 17-32 years old) treated with accelerated col...

journal_title：Current eye research

authors： Ozgurhan EB,Celik U,Bozkurt E,Demirok A

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:To determine retinal vessel diameter variations in response to neuronal activity induced by diffuse luminance flicker. METHODS:The diameter of retinal arteries and veins was measured in 9 normal subjects by computer analysis of fundus pictures taken in monochromatic light under normal conditions of illuminatio...

journal_title：Current eye research

authors： Formaz F,Riva CE,Geiser M

更新日期：1997-12-01 00:00:00

abstract：PURPOSE:The fibroblast growth factors (FGFs) are a family of 9 heparin binding proteins which have been proposed to play key roles in angiogenesis. Basic FGF (bFGF), acidic FGF (aFGF) and FGF5 have previously been demonstrated to be expressed in the normal retina and RPE. In this study, the expression of FGF5 was explo...

journal_title：Current eye research

authors： Kitaoka T,Morse LS,Schneeberger S,Ishigooka H,Hjelmeland LM

更新日期：1997-04-01 00:00:00

abstract：:The effect of cyclosporine (CsA) treatment in both primary and secondary Chlamydia trachomatis ocular infection in cynomolgus monkeys was studied. Following primary infection, CsA-treated animals developed severe clinical symptoms which persisted for up to 12 weeks compared to control animals which developed less seve...

journal_title：Current eye research

authors： Young E,Schachter J,Prendergast RA,Taylor HR

更新日期：1987-05-01 00:00:00

abstract：UNLABELLED:Purpose. To develop a rapid and accurate method for the quantification of reduced glutathione (GSH) and oxidized glutathione (GSSG) using micro-quantities of ocular lens. Methods. The epithelium, cortex and nucleus of the lens were separated and also the whole lens was homogenized in 3% metaphosphoric acid. ...

journal_title：Current eye research

authors： Liu S,Ansari NH,Wang C,Wang L,Srivastava SK

更新日期：1996-07-01 00:00:00

abstract：:Purpose: To investigate the cytotoxic effects of fresh black carbon (FBC) particles and ozone-oxidized BC (OBC) particles on human corneal epithelial cells (HCECs), and the role of the NLRP3 inflammasome signal pathway in the process.Methods: HCECs were treated with different doses of FBC and OBC particles, the cell i...

journal_title：Current eye research

authors： Long Q,Huang Y,Shang J,Liu Y,Chen C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To investigate glaucoma progression and its relationship with corrected and uncorrected intraocular pressure (IOP) in patients with a history of refractive corneal surgery (RCS). METHODS:Totally, 56 eyes of 56 primary open-angle glaucoma patients who had a history of RCS were included. Mean keratometry and cen...

journal_title：Current eye research

authors： Kwon J,Sung KR,Jo J,Yang SH

更新日期：2018-09-01 00:00:00